Abstract: The present invention relates to methods for culturing human retinal progenitor cells under low oxygen conditions to allow the cells to retain the ability to differentiate into photoreceptors following transplantation. The described methods provide cells that can treat a number of ocular diseases, including retinitis pigmentosa and age-related macular degeneration.

Abstract: A classification computing system provides adaptable taxonomies to facilitate user navigation of complex information systems. The classification computer includes a memory and a processor. The processor is configured to receive a collection of file indices from the information server. The processor is configured to apply a taxonomical classification algorithm to the collection to generate a collection of classified file indices. The classified file is associated with at least one taxonomical classification. The processor is further configured to apply a flow algorithm to the collection to generate at least one flow path used to provide a user access to a first subset of taxonomical classifications and restricts access to at least a second subset of taxonomical classifications. The flow path is responsive to user input parameters. The processor is configured to receive a user input parameter. The processor is additionally configured to provide the flow path to the user computing device.

Abstract: System and method are provided where parcels or packages are associated or grouped, into logical group or logical containerization of parcels or packages, without need for physical container, such that parcels or packages can be tracked as a group, for example with a unique group ID. Logical group may be tracked within specified logical zone on conveyor, transported, sorted and/or otherwise processed as unique logical group without need to be contained in physical container. System and method for automated sortation can accumulate set number or set volume of packages, and then process the accumulated set number or volume of packages.

Abstract: Disclosed herein is a fluid supply system that can provide fluid to a jetting assembly at a constant pressure or at pressures within a desired range of pressures. In an example, the fluid can be ink, and the jetting assembly can be a print head configured for dispensing the ink.

Abstract: A device for growing microorganisms. The device can include a self-supporting, water-proof substrate having an inner-facing surface and an outer-facing surface; a cover sheet having an inner-facing surface and an outer-facing surface, the cover sheet adhered to at least a portion of the substrate; a microstructured surface on the inner-facing surface of the coversheet, wherein the microstructured surface comprises a plurality of microstructures; a substantially dry, gelling agent and a substantially dry, microbial growth nutrient composition disposed on the microstructured surface of the microstructured film or on a portion of the inner-facing surface of the substrate.

Abstract: A server rack is cabled to obviate the need for top-of-rack switches. Switches and severs are connected through de-mateable connection interfaces at distribution modules disposed along the raceway above the server cabinets. The distribution modules may have externally accessible ports, internally accessible ports, and/or payout spools for the switch cables and/or the server cables.

Abstract: A tire change tool comprising a generally circular and planar faceplate having a hub side and a user side, the hub side and user side being generally parallel; an upper elbow flexibly connected to the faceplate by an interface; an arm connected to the upper elbow at a first end, and connected to a lower elbow at a lower end; and a footplate flexibly connected to the lower end of the arm by the lower elbow, wherein the faceplate and the interface comprise co-aligned apertures, the co-aligned apertures having an axis perpendicular to the plane of the faceplate. A length adjustment mechanism may be incorporated into the arm and adapted to permit the arm's length to be changed. The arm may include an upper section and a lower section adjustable connected by an adjustment mechanism adapted to permit the arm's length to be changed.

Abstract: An energy storage system comprising at least one energy storage module adapted to supply electrical energy to a hybrid vehicle. The energy storage module comprises an enclosure, at least one battery array located within the enclosure, and an energy storage controller module located within the enclosure and electrically connected to the battery array. The energy storage module further comprises a compliant tipped thermistor which may be installed within a flexible clip. The thermistor is positioned to monitor the temperature of one or more of the batteries within the energy storage system.

Abstract: System and method are provided where parcels or packages are associated or grouped, into logical group or logical containerization of parcels or packages, without need for physical container, such that parcels or packages can be tracked as a group, for example with a unique group ID. Logical group may be tracked within specified logical zone on conveyor, transported, sorted and/or otherwise processed as unique logical group without need to be contained in physical container. System and method for automated sortation can accumulate set number or set volume of packages, and then process the accumulated set number or volume of packages, including automatically closing a container filled with the packages.

Abstract: The current disclosure provides methods for reprogramming mammalian somatic cells by regulating the expression of endogenous cellular genes. Cellular reprogramming of somatic cells can be induced by activating the transcription of embryonic stem cell-associated genes (e.g., oct3/4) and suppressing the transcription of somatic cell-specific and/or cell death-associated genes. The endogenous transcription machinery can be modulated using synthetic transcription factors (activators and suppressors), to allow for faster, and more efficient nuclear reprogramming under conditions amenable for clinical and commercial applications. The current disclosure further provides cells obtained from such methods, along with therapeutic methods for using such cells for the treatment of diseases amendable to stem cell therapy, as well as kits for such uses.

Abstract: Systems and methods for nitric oxide (NO) generation systems are provided. In some embodiments, an NO generation system comprises at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas. The electrodes have elongated surfaces such that a plasma produced is carried by the flow of the reactant gas and glides along the elongated surfaces from a first end towards a second end of the electrode pair. A controller is configured to regulate the amount of NO in the product gas by the at least one pair of electrodes using one or more parameters as an input to the controller. The one or more parameters include information from a plurality of sensors configured to collect information relating to at least one of the reactant gas, the product gas, and a medical gas into which the product gas flows.

Abstract: Described herein is a multilayer article comprising: a. a polymer substrate comprising an abstractable atom; and b. a hydrogel coating thereon wherein the hydrogel coating has a water content of at least 10 wt % and is covalently bonded to the polymer substrate, and wherein the hydrogel coating is derived from an aqueous composition having a pH less than 9.5, the aqueous composition comprising: (a) a hydrophilic monomer selected from at least one of (meth)acrylate or (meth)acrylamide; (b) at least 0.1 wt % of a water-swellable clay; (c) a first initiator, wherein the first initiator is water-soluble and is a Type I photoinitiator; and (d) a second initiator, wherein the initiator is water-soluble and is a Type II photoinitiator; and (e) an acid.

Abstract: A method of depositing a nanoscale-thin film onto a substrate is disclosed. The method generally comprises depositing a layer of a solid or gaseous state functionalizing molecule onto or adjacent to the first surface of the substrate and exposing the first surface to a source of ionizing radiation, thereby functionalizing the first surface of the substrate. Once the layer of functionalizing molecule is removed, a nanoscale-thin film is then deposited onto the functionalized first surface of the substrate.

Abstract: A method of making a liquid laundry detergent formulation is provided, comprising: providing a liquid carrier; providing a cleaning surfactant; and selecting a cleaning booster of Formula (I) wherein x is 3 to 10; wherein y is 5 to 20; wherein z is 5 to 30; wherein x + y + z ? 18; wherein x ? z; wherein each R is a C7-9 alkyl group, wherein ? 75 wt% of the R groups are branched; wherein the selected cleaning booster of Formula (I) is selected based its cleaning boosting properties; providing the selected cleaning booster of Formula (I); and combining the liquid carrier, the cleaning surfactant and the selected cleaning booster of Formula (I) to provide the liquid laundry detergent formulation.

Abstract: Embodiments are directed towards a use of a supported gas-phase biphenylphenol polymerization catalyst to make a polymer via a gas-phase polymerization process, wherein the supported gas-phase biphenylphenol polymerization catalyst is made from a gas-phase biphenylphenol polymerization precatalyst of Formula I.

Abstract: A method of depositing a nanoscale-thin film onto a substrate is disclosed. The method generally comprises depositing a layer of a solid or gaseous state functionalizing molecule onto or adjacent to the first surface of the substrate and exposing the first surface to a source of ionizing radiation, thereby functionalizing the first surface of the substrate. Once the layer of functionalizing molecule is removed, a nanoscale-thin film is then deposited onto the functionalized first surface of the substrate.

Abstract: A liquid laundry detergent formulation is provided, comprising: a liquid carrier; a cleaning surfactant; and a cleaning booster, wherein the cleaning booster is of Formula (I) wherein x is 3 to 10; wherein y is 5 to 20; wherein z is 5 to 30; wherein x+y+z?18; wherein x?z; wherein each R is a C7-9 alkyl group and wherein ?75 wt % of the R groups are branched.

Abstract: Progenitor cells were isolated, purified and expanded using a microfluidic based cell sorting approach. The methods were successfully in purifying cone progenitor cells (CPCs) defined based on a proliferative population expressing cone arrestin and Red/Green (R/G) opsin at greater than 80% using a two multistage approach.

Abstract: The invention is directed to the characterization of an optical channel, such as an optical fiber, in an optical network. The method includes calibrating a transmitter by measuring its transmitter and dispersion eye closure (TDEC, in the case of non-return to zero optical (NRZ) optical systems or transmitter and dispersion eye closure quaternary (TDECQ, in the case of 4-level pulse amplitude modulation (PAM4) optical systems). That calibrated transmitter is used to characterize the optical channel being tested by providing a measure of its stressed eye closure (SEC) or stressed eye closure quaternary (SECQ). A loss deficit for the optical channel can be calculated by subtracting the SEC or SECQ value from the maximum TDEC or TDECQ value.

Abstract: A method, apparatus and computer program product are provided for validating electronic distribution transactions and reducing non-compliant electronic distribution transactions. A distribution application enables users to enter details relating to a retirement account distribution. A tax service integrated with the distribution application provides scenario-specific tax withholding information, and enforces relevant tax withholding rules. A user provides withholding information and the system ensures compliance by validating the transaction against the withholding rules. The system displays to the user any errors that need to be corrected, and a breakdown of the proceeds from the transaction. The tax service is implemented remotely from the distribution application so that changing tax regulations may be implemented into the tax service without impacting the distribution application.