Abstract: Methods and systems are disclosed for selecting a print head of a 3D printing machine to apply 3D printing material at one or more positions in a printed 3D object. Embodiments of the present invention may include, in the selection process one or more elements pertaining for example to: geometry of the received 3D model; colorization of the received 3D model; transparency of the received 3D model; properties of the 3D printing material; and constraints of the 3D printing machine.

Abstract: Methods and compositions disclosed herein generally relate to methods of improving clinical and economic outcomes to address adverse effects related to anesthesia, analgesics, opioids, and inadequate pain relief. Embodiments of the invention relate to the association between genes, specific polymorphisms of genes, and non-genetic factors with inadequate pain relief and anesthesia-, analgesic, and/or opioid-related adverse effects. Embodiments of the invention can be used to determine and manage patient risk factors for development of adverse perioperative effects and can allow for personalized anesthesia and pain management for improvement of pain control and reduction of anesthesia-, analgesic-, and opioid-related adverse outcomes. These methods and compositions apply to non-surgical pain management with opioids.

Abstract: A system includes a laminated glass comprising a protective layer disposed between two sheets of glass. The system includes a resistive conductive coating made of a first electrically conducting material disposed on a surface of one of the two sheets of glass facing the protective layer. The system includes a first set of electrodes made of a second electrically conducting material disposed on the resistive conductive coating. The system includes a second set of electrodes made of a third electrically conducting material disposed on the first set of electrodes. The second set of electrodes is electrically connected to the first set of electrodes, respectively. The third electrically conducting material of the second set of electrodes is more ductile than the second electrically conducting material of the first set of electrodes.

Abstract: A method of distinguishing a subject with pre-clinical Alzheimer's disease from those with similar symptoms but other forms of dementia such as mild cognitive impairment. The blood RNA whole transcriptome profile of a subject with suspected pre-clinical Alzheimer's disease is obtained and analyzed against a reference blood RNA whole transcriptome profile from a subject with another form of dementia such as frontal temporal dementia, CADASIL or mild cognitive impairment (MCI). The blood RNA whole transcriptome profile includes the presence and quantitation of ncRNA. Methods to enhance treatment of epileptic seizures are also discussed.

Abstract: The disclosure provides methods of modulating an immune response by inhibiting BFL1, and related methods for treating and preventing diseases and disorders characterized by inflammation, especially neutrophil induced inflammation.

Abstract: Techniques for matrix multiplication are described. In some examples, decode circuitry is to decode a single instruction having fields for an opcode, an indication of a location of a first source operand, an indication of a location of a second source operand, and an indication of a location of a destination operand, wherein the opcode is to indicate that execution circuitry is to at least convert data elements of the first and second source operands from a first floating point representation to a second floating point representation, perform matrix multiplication with the converted data elements, and accumulate results of the matrix multiplication in the destination operand in the first floating point representation; and the execution circuitry is to execute to the decoded instruction as specified by the opcode.

Abstract: A generator comprising a rotor, at least one magnetic bridging element arranged to rotate about a rotation axis of the rotor in response to the rotation of the rotor, at least one inductance unit at an area of an influence of the moving magnetic bridging element for inducing electromotive force in response to the movement of the magnetic bridging element relative to the inductance unit, and at least one flow channel unit for conveying a fluid flow to the rotor for operating the rotor.

Abstract: Methods and systems are disclosed for selecting a print head of a 3D printing machine to apply 3D printing material at one or more positions in a printed 3D object. Embodiments of the present invention may include, in the selection process one or more elements pertaining for example to: geometry of the received 3D model; colorization of the received 3D model; transparency of the received 3D model; properties of the 3D printing material; and constraints of the 3D printing machine.

Abstract: Methods and kits for detecting the presence of at least one target DNA sequence with or without a modification in a DNA molecule are provided.

Abstract: The disclosure provides compounds of Formula I and their use in methods of modulating an immune response by inhibiting BFL1, and related methods for treating and preventing diseases and disorders characterized by inflammation, especially neutrophil induced inflammation.

Abstract: The present disclosure relates to a method for integrity verification of a software stack or part of a software stack resident on a host machine. A management entity generates a measurement log for a disk image associated with the software stack or the part of a software stack. A verifier entity retrieves the generated measurement log and compares the generated measurement log with a reference measurement of a verification profile previously assigned by the verifier entity to the software stack or the part of a software stack to verify the software stack or the part of a software stack.

Abstract: Devices for detecting a molecule of interest comprising an electrokinetic focusing apparatus and a nanopore apparatus are provided. Kits and systems comprising the apparatus are also provided; as are methods of detecting molecules of interest comprising running the molecules through the electrokinetic focusing apparatus and then detecting the focused molecules as they pass through the nanopore.

Abstract: The present disclosure relates to a method for integrity verification of a software stack or part of a software stack resident on a host machine. A management entity generates a measurement log for a disk image associated with the software stack or the part of a software stack. A verifier entity retrieves the generated measurement log and compares the generated measurement log with a reference measurement of a verification profile previously assigned by the verifier entity to the software stack or the part of a software stack to verify the software stack or the part of a software stack.

Abstract: A method of diagnosing the likelihood of recurrence of clear cell renal cell carcinoma is provided. The method involves a) detecting the gene expression signatures of mitochondrial electron transport chain subunits, mitochondrial ribosomal proteins, major histocompatibility complex class II (MHC-II) proteins or combinations thereof in a kidney tumor tissue sample; and b) determining that the subject has an elevated risk of recurrence of clear cell renal cell carcinoma if the gene expression signatures include certain sequences. In another embodiment, the method uses copper levels to diagnose the likelihood of recurrence of clear cell renal cell carcinoma.

Abstract: A device can be introduced into the right atrium of a subject's heart by introducing the distal end of a hollow, straight, and stiff shaft into the subject's right internal jugular vein, and advancing the distal end of the shaft into the right atrium via the superior vena cava. The position of the distal end of the shaft is adjusted by manipulating a handle affixed to a portion of the shaft that remains outside the subject's body. The handle can be used to rotate the shaft about its longitudinal axis, rotate the shaft about an anterior-posterior axis, rotate the shaft about a medial-lateral axis, and/or advance the shaft in the caudal direction. A device is advanced through the interior of the shaft until the device extends beyond the distal end of the shaft and into the right atrium.

Abstract: A method for electrical charging of an energy storage of a motor vehicle at a motor vehicle external charger, wherein at least one charging constraint specified by a user of the motor vehicle specifically for the upcoming charging process of the energy storage is detected, and a charging current for the upcoming charging process is determined depending on the at least one charging constraint, and the charging process is performed depending on the determined charging current.

Abstract: Methods for identifying a peptide by analyzing a linear readout representative of at least a portion of at least two amino acids along the peptide using a machine learning model, wherein the machine learning model is trained on linear readouts representative of a set of peptides of known sequence are provided. Methods of training a machine learning model on linear readouts representative of a set of known peptides, and systems for performing the methods of the invention are also provided.

Abstract: Systems comprising a light source, thin membrane immersed in an aqueous solution and a system to direct and focus light from the light source to a spot on the membrane are provided. Methods of thinning and etching a membrane are also provided, as are membranes comprising a nanopore with a Gaussian curve shaped cross-section.

Abstract: There is provided a method of recursive sequential list decoding of a codeword of a polar code comprising: obtaining an ordered sequence of constituent codes usable for the sequential decoding of the polar code, representable by a layered graph; generating a first candidate codeword (CCW) of a first constituent code, the first CCW being computed from an input model informative of a CCW of a second constituent code, the first constituent code and second constituent code being children of a third constituent code; using the first CCW and the second CCW to compute, by the decoder, a CCW of the third constituent code; using the CCW of the third constituent code to compute a group of symbol likelihoods indicating probabilities of symbols of a fourth (higher-layer) constituent code having been transmitted with a particular symbol value, and using the group of symbol likelihoods to decode the fourth constituent code.

Abstract: A solar tracker waterless cleaning system for cleaning solar panels of a solar tracker being able to be positioned at a pre-determined angle, including a docking station and an autonomous robotic cleaner (ARC), the docking station coupled with an edge of the solar tracker, the ARC including at least one rechargeable power source, at least one cleaning cylinder, at least one edge sensor, at least one cleaning cylinder direct current (DC) drive motor including a built-in encoder, a cleaning cylinder drive belt and a controller, the cleaning cylinder including a plurality of fins which rotates for generating a directional air flow for pushing dirt off of the surface of the solar tracker without water, the cleaning cylinder DC drive motor for driving the cleaning cylinder, the controller for controlling a cleaning process of the ARC, the built-in encoder for determining a revolutions per minute (RPM) of the cleaning cylinder.