Abstract: Disclosed is a method of signaling hopping locations selected by a scheduling entity using a frequency hopping pattern indicator for indicating hopping locations for at least two re-transmissions. The frequency hopping pattern is selected by the scheduling entity which may have knowledge of all or at least a plurality of scheduled reverse link transmissions or restrictions upon reverse link transmissions, thereby allowing reverse link re-transmissions to be scheduled in a manner compatible with other reverse link transmissions and restrictions. Overall signaling overhead associated with scheduling re-transmissions is reduced through the signaling of a single message which indicates hopping locations for at least two re-transmissions instead of two or more separate messages, wherein each of the two or more separate message indicates a hopping location for an individual re-transmission.

Abstract: The invention relates to imatinib for use in tumor therapy. This invention describes a stable, non hygroscopic alpha crystalline form of methane sulfonic acid addition salt of 4-(4-methyl piperazin-1-yl methyl)-N-[4-methyl-3-(4-pyridin-3-yl)-pyrimidin-2-yl amino) phenyl]-benzamide (imatinib mesylate) having the general structural formula A process for the preparation of the crystalline form is also described.

Abstract: The present disclosure provides isolated monoclonal antibodies that specifically bind to mesothelin with high affinity, particularly human monoclonal antibodies. Preferably, the antibodies bind human mesothelin. In certain embodiments, the antibodies are capable of internalizing into mesothelin-expressing cells or are capable of mediating antigen dependent cellular cytotoxicity. The invention further provides anti-mesothelin antibodies that can inhibit the binding of mesothelin to the ovarian cancer antigen CA125. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Antibody-partner molecule conjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided.

Abstract: The invention provides a method of inhibiting the effects of platelet activating factor (PAF). For instance, a disease or condition mediated by PAF (particularly inflammation) can be treated or platelet aggregation can be inhibited. The invention also provides a method of inhibiting the production and/or release of interleukin 8 (IL-8) by cells. The effects of PAF and the production and/or release of IL-8 are inhibited according to the invention by a compound of the formula: wherein R1 and R2 are defined in the application, or a physiologically-acceptable salt thereof. The invention also provides pharmaceutical compositions comprising these compounds.

Abstract: Methods, systems and apparatus for characterizing networks are presented. For example, a method of characterizing a network represented by a plurality of nodes and a plurality of edges is provided. The method may be implemented on a processor device and includes calculating, for example, by the processor device, a passthrough count of at least a portion of the network. The passthrough count includes a count of a number of passthroughs in the at least a portion of the network. A passthrough includes one of the plurality of nodes, a directed edge of the plurality of edges coupled to the one of the plurality of nodes, and another edge of the plurality of edges coupled to the one of the plurality of nodes. At most one of the directed edge and the other edge is directed towards the one of the plurality of nodes. At most one of the directed edge and the other edge is directed away from the one of the plurality of nodes.

Abstract: A rapid, sensitive and cost effective process of detection of swine flu virus H1 type in a sample is provided herein. The present invention further provides highly specific oligonucleotides useful for rapid detection of swine flu virus in a sample. Swine flu virus specific isothermal gene amplification assay disclosed in the present invention is highly specific and sensitive and is useful for early clinical diagnosis of H1N1 human patients. The oligonucleotides disclosed in the present invention provide amplification of the target gene in highly sensitive and specific manner showing no cross amplification.

Abstract: The various embodiments of the present invention provide a novel chip-last embedded structure, wherein an IC is embedded within a one to two metal layer substrate. The various embodiments of the present invention are comparable to other two-dimensional and three-dimensional WLFO packages of the prior art as the embodiments have similar package thicknesses and X-Y form factors, short interconnect lengths, fine-pitch interconnects to chip I/Os, a reduced layer count for re-distribution of chip I/O pads to ball grid arrays (BGA) or land grid arrays (LGA), and improved thermal management options.

Abstract: The invention provides a coated inorganic oxide pigment. The inventive coated inorganic oxide pigment comprises an inorganic oxide base pigment, a porous inorganic coating formed on the base pigment, and a dense inorganic coating formed on the base pigment. The porous inorganic coating and dense inorganic coating each consist essentially of a material selected from the group consisting of silica and alumina. In another aspect, the invention provides a method of manufacturing a coated inorganic oxide pigment. In yet another aspect, the invention provides a polymer composition comprising a base polymer, and a coated inorganic oxide pigment admixed with the base polymer.

Abstract: Disclosed herein are nanoparticle, micelle and/or liposome compositions, each comprising a therapeutic agent encapsulated in one or more polymer(s), wherein a vitamin B12 or a derivative thereof is attached to the one or more polymer(s) via a linker group, as well as methods for making and using same.

Abstract: A mobile device that receives a streaming content that it shares with other devices in its vicinity/proximity. The mobile device comprises a communication circuitry that facilitates establishing a communication link with a plurality of other mobile devices. The mobile device receives the streaming content and shares it with substantial synchronization with the plurality of other mobile devices in real time employing the communication circuitry. The mobile device manages synchronized viewing of the streaming content with the plurality of other mobile devices by coordinating pauses, buffering, resumptions, restarts and terminations based on events reported by the mobile device and by the plurality of other mobile devices it is communicatively coupled with.

Abstract: A digital document display device capable of displaying a document, retrieving updates, sharing locally with other devices, managing document displays in other digital document display devices in proximity, etc. A e-paper based display unit of the digital document display device is configured to read and display the display image. A motion detector unit helps detect human motion, so that the digital document display device may be set to a low power mode, or powered off, etc. if no humans are detected in the vicinity. A renewable energy power unit is also provided.

Abstract: The invention relates to a multi-cellulase enzyme composition for the enzymatic hydrolysis of cellulosic biomass said composition comprising a cellobiohydrolase (CBH) enzyme, an endoglucanase (EG) enzyme and a ?-glucosidase (BG) enzyme.

Abstract: An interconnector coupling permeate conduits in a filtration apparatus includes a diverging section. The diverging section defines a generally increasing cross sectional area for the permeate solution exiting the interconnector in a direction of flow from the permeate conduit of a first separation element to a permeate conduit of a second separation element. The diverging section provides a more gradual divergence of the permeate solution to reduce pressure losses.

Abstract: The invention discloses phytochemical agents derived from Holoptelea integrifolia and novel composition(s) comprising at least one component selected from the extract(s), fraction(s) and active compound(s) for the protection and alleviation of Metabolic Syndrome, insulin resistance, endothelial dysfunction, chronic kidney disease, atherosclerosis, diabetes and other disease conditions associated with metabolic syndrome. The invention also discloses the amelioration of certain biomarker molecules such as Peroxisome proliferator-activated receptor gamma (PPAR-?), Adipose Differentiation Related Protein (ADRP), CD36, Adipocyte Fatty-acid-Binding Protein (aP2/FABP-4/A-FABP), beta-3 Adrenergic Receptor (?3AR), Leptin, Perilipin and Adiponectin by using the phytochemical components derived from Holoptelea integrifolia.

Abstract: The invention relates to various new polymorphic forms of manidipine and pharmaceutically acceptable salts thereof. The invention also relates to processes for the preparation of the polymorphic forms of manidipine and pharmaceutically acceptable salts thereof.

Abstract: An arrangement, a method and a system to read information stored in a layer of ferroelectric media. The arrangement includes a layer including a ferroelectric media having one or more ferroelectric domains holding bit charges, a domain corresponding to information; a probe having a tip, wherein the media and the tip are adapted to move relative to one another such that the tip scans the ferroelectric domains of the media while applying a contact force to the domains to generate a direct piezoelectric effect within the domains; and circuitry coupled to the tip and adapted to generate a signal in response to an electrical coupling between the tip and the domains while scanning the tip in contact with the domains, the signal corresponding to a readout signal for ferroelectric bit charges stored in the media.

Abstract: The present invention provides compounds of Formula (I) and (II), or a pharmaceutically acceptable salts thereof, where R53, R54, p, q, and n are as defined herein. The compounds of the present invention have been found to be useful as 17?-hydroxylase/C17,20-lyase inhibitors.

Abstract: A process is disclosed for making CF3CF?CHF. The process involves reacting CF3CClFCCl2F with H2 in a reaction zone in the presence of a catalyst to produce a product mixture comprising CF3CF?CHF. The catalyst has a catalytically effective amount of palladium supported on a support selected from the group consisting of alumina, fluorided alumina, aluminum fluoride and mixtures thereof and the mole ratio of H2 to CF3CClFCCl2F fed to the reaction zone is between about 1:1 and about 5:1. Also disclosed are azeotropic compositions of CF3CClFCCl2F and HF and azeotropic composition of CF3CHFCH2F and HF.

Abstract: Provided are coated oil and gas well production devices and methods of making and using such coated devices. In one form, the coated oil and gas well production device includes an oil and gas well production device including one or more bodies, and a coating on at least a portion of the one or more bodies, wherein the coating is chosen from an amorphous alloy, a heat-treated electroless or electro plated based nickel-phosphorous composite with a phosphorous content greater than 12 wt %, graphite, MoS2, WS2, a fullerene based composite, a boride based cermet, a quasicrystalline material, a diamond based material, diamond-like-carbon (DLC), boron nitride, and combinations thereof. The coated oil and gas well production devices may provide for reduced friction, wear, corrosion, erosion, and deposits for well construction, completion and production of oil and gas.

Abstract: An apparatus and method are used to enhance the sensitivity of a spectrometer (sensor) for trace gas species detection by employing an external cavity continuously tunable CW quantum cascade laser and integrating the absorption spectra across multiple lines of the species. With this method the absorption spectra of NO2 is continuously recorded across the R-branch from 1628.8 cm?1 to 1634.5 cm?1. By integrating the resulting spectra, the detection sensitivity for NO2 is improved by a factor of 15 compared to the sensitivity achieved using single line laser absorption spectroscopy with the same apparatus. This procedure offers much shorter data acquisition times for the real-time monitoring of trace gas species compared with adding repeated scans of the spectra to improve the signal-to-noise ratio.