Abstract: In one example, a device includes one or more processors, a presence-sensitive display, and a storage device that stores one or more modules. The modules are executable to, responsive to receiving an indication of a first user input: output, for display, a graphical element including at least one task shortcut from a plurality of task shortcuts for an application, receive an indication of a second user input that selects a particular task shortcut included in the graphical element, and, responsive to receiving the indication of the second user input, output, for display, a shortcut icon for the particular task shortcut within the graphical user interface.

Abstract: The invention generally relates to optical methods for the diagnosis of neuronal condition by converting a cell from a patient into a neuron and optically evaluating action potentials of that cell in vitro. The cell is transformed with an optical reporter and exhibits an optical signature in response to neural stimulation. Using genome-editing, a control cell can be made that is isogenic but—for a known mutation and a control signature obtained from the control cell. Thus, methods of the invention reveal potential neurodegenerative effects of a mutation as manifested in a patient's genetic context.

Abstract: Methods, systems, and computer programs, for predicting a likely outcome for an entity. A method includes obtaining a first data structure that includes data that represents a transaction, determining a similarity level of the transaction to each of a plurality of categories, determining a transaction category based on the determined similarity level, generating an input data structure that includes data representing (i) at least a portion of the data representing the transaction, and (ii) data describing the determined category, providing the input data structure to a predictive algorithm trained to determine a value that represents a likely outcome for an entity that initiated a transaction, obtaining output generated by the predictive algorithm based on the predictive algorithm's processing of the input data structure, the output including a value that represents a likely outcome for the entity, and determining a likely outcome for the entity based on the obtained output.

Abstract: Methods, systems, and computer programs, for predicting a likely outcome for an entity. A method includes obtaining a first data structure that includes data that represents a transaction, determining a similarity level of the transaction to each of a plurality of categories, determining a transaction category based on the determined similarity level, generating an input data structure that includes data representing (i) at least a portion of the data representing the transaction, and (ii) data describing the determined category, providing the input data structure to a predictive algorithm trained to determine a value that represents a likely outcome for an entity that initiated a transaction, obtaining output generated by the predictive algorithm based on the predictive algorithm's processing of the input data structure, the output including a value that represents a likely outcome for the entity, and determining a likely outcome for the entity based on the obtained output.

Abstract: To extract meaningful information that aids in analysis of a web application or web site based on page summarizations without impractical resource demand, statistical modeling is employed to approximately identify pages across web application transactions and predict meaningful content or items of information within the pages. Statistics are collected on a sample of traffic for a web application. The collected statistics are on tokens generated from messages that correspond to web pages. Statistics are collected by message, by transaction, and across the sampling of messages. Descriptive tokens that meaningfully describe a web page and attribute-value pair tokens are scored. Those of the tokens that satisfy selection criteria are selected as a basis for generating extraction rules. Subsequently, the extraction rules are applied to message payloads to efficiently extract descriptive “tags” and attribute-value pairs.

Abstract: A system can be designed that shares transaction data across different organizations while preserving data privacy and anonymizing the source organization. Organizations can enter into an agreement to share transaction data with each other through a trusted data sharing system. The organizations can input user records that include primary and secondary explicit user identifiers into the data sharing system. The data sharing system can correlate explicit user identifiers of a user across organizations via an internal identifier without exposing explicit user identifiers. The data sharing system comprises a data anonymizer agent for each sharing organization. A data anonymizer agent selectively applies anonymization filters to quasi-identifiers in the transaction data based on quasi-identifier type to extend data privacy protection measures to quasi-identifiers without drastically reducing or eradicating the utility of the quasi-identifiers.

Abstract: The invention generally relates to optical methods for the diagnosis of neuronal condition by converting a cell from a patient into a neuron and optically evaluating action potentials of that cell in vitro. The cell is transformed with an optical reporter and exhibits an optical signature in response to neural stimulation. Using genome-editing, a control cell can be made that is isogenic but-for a known mutation and a control signature obtained from the control cell. Thus, methods of the invention reveal potential neurodegenerative effects of a mutation as manifested in a patient's genetic context. The optical signature of the cell, or the difference between the signature and the control signature, is correlated to a diagnosis of the neurodegenerative disease.

Abstract: Rapidly handling large data sets can be a challenge, particularly in situations where there are millions or even hundreds of millions of database records. Sometimes, however, a service level agreement necessitates that a service return a response to a query in a small amount of time. Database organization techniques can be used that reduce potentially large datasets to smaller groups (neighbors) based on uncommon but shared attributes, in various instances. Using a limited set of related records, queries can be answered using a focused approximation based on characteristics of various identified clusters of records in the set of related records. A particular record may also be associated with an existing cluster of records based on that record's similarities to records in the cluster.

Abstract: Methods and systems are presented for classifying a particular user account as a fraudulent user account by analyzing links between the user account and two or more known fraudulent user accounts collectively. Attributes of the particular user account are compared against attributes of a plurality of known fraudulent accounts to determine that the particular user account has shared attributes with a first known fraudulent account and a second known fraudulent account. The shared attributes with the first known fraudulent account and the second known fraudulent account are analyzed collectively to determine a risk level for the particular user account. The risk level may indicate a likelihood that the particular user account corresponds to a fraudulent account.

Abstract: An apparatus for segmenting and feeding a fiber includes at least one capillary having a lumen therethrough configured to deliver a fiber segment. An advancing advances a fiber through the capillary. Tensioning means applies tension to the fiber to induce it to break. Damaging means locally damages the fiber.

Abstract: The present invention includes a process, system and apparatus for multi-material additive manufacturing process comprising: extruding an extrudable material through a nozzle capable of moving along one or more axis and concurrently extruding one or more filaments, wherein the filament is embedded in, on or about the extrudable material from the nozzle.

Abstract: A computing device is described that receives, from a source, a notification. The computing device determines content of the notification other than a quantity of notifications currently pending for the source of the notification and based at least in part on the content, determines a notification badge that reflects the content of the notification. The device displays the notification badge near a graphical element for launching the source of the notification. In reflecting content of the notification, the badge icon may facilitate efficient interaction with the computing device by resolving one or more ambiguities that would otherwise arise.

Abstract: Various systems, mediums, and methods may involve a data engine with various components. For example, a system with the data engine may include a segmentation component, an asset preparation component, a clustering component, a variable generation component, and classification component. As such, the system may determine a number of assets associated with a number of activities of one or more accounts. Further, the system may determine various links associated with the number of assets. As such, the system may detect an attack and/or an attack trend associated with the one or more accounts based on the various links associated with the number assets. Further, the system may generate a notification that indicates the attack and/or the attack trend detected.

Abstract: Machine learning techniques are used in combination with graph data structures to perform automated classification of accounts. Graphs may be constructed using a seed node and then expanded outward to second-degree nodes and third-degree nodes that are connected to a seed user account node via direct interaction between the accounts. Characterization information regarding the interaction between accounts can be stored in the graph (e.g., quantity of interactions, types of interactions) as well as other metrics and metadata. A classifier, using random forest or another technique, may be trained using a number of different graphs that can then be used to reach a determination as to whether a user account falls into one particular category or another. These techniques can identify accounts that may be violating terms of service, committing a security violation, and/or performing illegal actions in a way that is not ascertainable from human analysis.

Abstract: Various systems, mediums, and methods may involve a data engine with various components. For example, a system with the data engine may include a segmentation component, an asset preparation component, a clustering component, a variable generation component, and classification component. As such, the system may determine a number of assets associated with a number of activities of one or more accounts. Further, the system may determine various links associated with the number of assets. As such, the system may detect an attack and/or an attack trend associated with the one or more accounts based on the various links associated with the number assets. Further, the system may generate a notification that indicates the attack and/or the attack trend detected.

Abstract: A computer readable medium and a method for bandwidth management, the method may include receiving or generating (a) video entity quality information for multiple sets of video entities, each set of video entities comprises video entities that belong to different versions of a same video stream, (b) user device screen size information for each user device out of multiple users devices, (c) user device profile information for each user out of multiple users, and (d) bandwidth constraints relating to bandwidth available for transmission of selected video entities to the user devices; wherein each user of the multiple users is associated with a user device of the multiple users devices; selecting for each user device a selected video entity based on at least (a) the video entity quality information, (b) the user device screen size information, (c) the requested video profile information, and (d) the bandwidth constraints; and, streaming to the multiple user devices from multiple selected video entities.

Abstract: Additive manufacturing methods and apparatus are described for the direct, automated, tooling-less fabrication of composite parts with complex shapes such as fiber-reinforced composite parts with isotropic properties. In some embodiments, fibers parallel to one axis (e.g. Z) are provided initially (e.g., as a preform) and layers are fabricated by selectively curing a resin around these fibers while adding other fibers with other orientations. In some embodiments, fibers are rendered substantially transparent by immersing them in a refractive index matching liquid, thus allowing selective curing of a resin in the presence of the fibers.

Abstract: A method is provided that includes accessing, by a server provider server of a service provider, a database storing associations between network addresses and locations. Additionally, the method includes determining a subset of the database corresponding to a first network address, each association included in the subset corresponding to an association between the first network address and a respective location. The method also includes in response to determining that the subset of the database satisfies one or more clustering criteria, calculating a representative location corresponding to the first network address, and storing an association between the first network address and the representative location in a second database.

Abstract: Provided is an advanced liquid centrifuge using differentially rotating cylinders moveable rings at the ends thereof, as well as methods for the separation of fluids, preferably liquids.

Abstract: The invention provides an open-stage near-TIRF microscope in which all of the optical components are positioned underneath the sample, allowing for physical access to, and control over the environment of, the sample. The microscope can be used to image cells expressing fluorescent voltage indicators. Since the TIRF components do not interfere with the sample, living cells can be studied using a microscope of the invention. Where a sample includes electrically active cells expressing fluorescent voltage indicators, the microscope can be used to view voltage changes in, and thus the electrical activity of, those cells.