Patents by Inventor Adrian D'Lima

Adrian D'Lima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULAR FLOW CASSETTE
    Publication number: 20150000664
    Abstract: A flow cassette has a housing with an inlet and an outlet and a passage therebetween. The flow cassette also has a temperature sensor disposed within the passage and configured to measure the temperature of a fluid flowing through the passage, a flow rate sensor disposed within the passage and configured to measure a flow rate of the fluid flowing through the passage, and a processor coupled to the temperature sensor and flow rate sensor. The processor is configured to accept measurements of temperature and flow rate from the temperature sensor and flow rate sensor, respectively, and provide a compensated flow rate.
    Type: Application
    Filed: June 28, 2013
    Publication date: January 1, 2015
    Inventors: Adrian D. DESILVA, Huy Thanh Vu, Richard Le, Jeffrey Harold Miller, Hector Gonzalez, Raul Valdez, Chiun Wang
  • System and method for minimizing network transition latencies while minimizing power consumption
    Patent number: 8897152
    Abstract: A user device establishes a wireless connection with a wireless local area network using a first radio. The user device then deactivates a second radio of the user device based on establishing of the wireless connection with the wireless local area network. Subsequently, the user device determines whether to activate the second radio based on at least one criterion associated with the wireless connection.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: November 25, 2014
    Assignee: Amazon Technologies, Inc.
    Inventors: Adrian D. Caceres, Vlad Troyanker, Jalaja C. Kurubarahalli, Marc Solsona-Palomar
  • 5-SUBSTITUTED INDAZOLES AS KINASE INHIBITORS
    Publication number: 20140343066
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R1, R2, R3 and m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), Cdc7, AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 20, 2014
    Inventors: Irini Akritopoulou-Zanze, Brian D. Wakefield, Helmut Mack, Sean C. Turner, Alan F. Gasiecki, Vijaya J. Gracias, Kathy A. Sarris, Douglas M. Kalvin, Melissa J. Michmerhuizen, Qi Shuai, Jyoti R. Patel, Margaretha H.M. Bakker, Nicole Teusch, Eric F. Johnson, Peter J. Kovar, Stevan W. Djuric, Andrew J. Long, Anil Vasudevan, Dawn M. George, Lu Wang, Biqin Li, Nigel S. Moore, Adrian D. Hobson, Keith W. Woods, Julie M. Miyashiro, Steven L. Swann, Jr., Thomas D. Penning
  • CONTENT CLASSIFICATION OF INTERNET TRAFFIC
    Publication number: 20140334304
    Abstract: A content-classification model is constructed using sampling methods to create training sets of classifiers using imbalanced and/or large-volume training data; the model maps network source addresses and/or flow sizes to target applications and is applied to network traffic to identify contents thereof and estimate a tonnage of traffic corresponding to a given application.
    Type: Application
    Filed: September 13, 2013
    Publication date: November 13, 2014
    Inventors: Hui Zang, Adrian D. Fritsch, Mark Crovella
  • KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY
    Publication number: 20140286864
    Abstract: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides.
    Type: Application
    Filed: December 17, 2013
    Publication date: September 25, 2014
    Applicants: Bracco Suisse SA, Dyax Corp.
    Inventors: AARON K. SATO, DANIEL J. SEXTON, DANIEL T. DRANSFIELD, ROBERT CHARLES LADNER, CHRISTOPHE ARBOGAST, PHILIPPE BUSSAT, HONG FAN, SUDHA KHURANA, KAREN E. LINDER, EDMUND R. MARINELLI, PALANIAPPA NANJAPPAN, ADRIAN D. NUNN, RADHAKRISHNA K. PILLAI, SIBYLLE POCHON, KONDAREDDIAR RAMALINGAM, AJAY SHRIVASTAVA, BO SONG, ROLF E. SWENSON, MATHEW A. VON WRONSKI, FENG YAN
  • MONOLITHIC INTEGRATED CIRCUIT (MMIC) STRUCTURE AND METHOD FOR FORMING SUCH STRUCTURE
    Publication number: 20140284661
    Abstract: A method for forming a semiconductor structure having a transistor device with a control electrode for controlling a flow of carriers between a first electrode and a second electrode. A passivation layer is deposited over the first electrode, the second electrode and the control electrode. An etch stop layer is deposited on the passivation layer over the control electrode. A dielectric layer is formed over the etch stop layer. A window is etched through a selected region in the dielectric layer over the control electrode, to expose a portion of the etch stop layer disposed over the control electrode. A metal layer is formed on a portion of the etch stop layer and the dielectric layer is also formed on the metal layer. A second metal layer is deposited on the portion of the dielectric layer formed on the first mentioned metal layer.
    Type: Application
    Filed: March 25, 2013
    Publication date: September 25, 2014
    Applicant: Raytheon Company
    Inventors: Adrian D. Williams, Paul M. Alcorn
  • TRIAZINONE COMPOUNDS
    Publication number: 20140206663
    Abstract: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
    Type: Application
    Filed: March 19, 2014
    Publication date: July 24, 2014
    Inventors: Jianfei Wang, Eric C. Breinlinger, Martine Barth, Michael M. Friedman, Fabrice Guillier, Maria A. Argiriadi, Jeremy Edmunds, Dominique Potin, Adrian D. Hobson, Wentao Wu, Dominique Bonafoux, Didier Thomas, Dawn M. George, Linlin Dai, Yang Zhang
  • MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS
    Publication number: 20140205545
    Abstract: The invention provides compositions and methods for therapeutic and diagnostic applications.
    Type: Application
    Filed: September 19, 2013
    Publication date: July 24, 2014
    Applicants: Dyax Corp., Bracco Suisse S.A.
    Inventors: Hong FAN, Karen E. Linder, Edmund R. Marinelli, Palaniappa Nanjappan, Adrian D. Nunn, Radhakrishna K. Pillai, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf E. Swenson, Mathew A. Von Wronski, Aaron K. Sato, Sharon Michele Walker, Daniel T. Dransfield
  • Aminopyrrolidines as chemokine receptor antagonists
    Patent number: 8754107
    Abstract: The present invention is directed to novel aminopyrrolidines of formula I pharmaceutically acceptable salts thereof, metabolites thereof, isomers thereof, stereoisomers thereof or pro-drugs thereof, wherein the variables are as defined herein. The compounds of formula (I) are useful as chemokine receptor antagonists and as such would be useful in treating certain conditions and diseases, especially inflammatory conditions and diseases and proliferative disorders and conditions, for example, cancers.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: June 17, 2014
    Assignee: AbbVie Inc.
    Inventors: Dawn M. George, Richard W. Dixon, Michael Friedman, Adrian D. Hobson, Biqin Li, Lu Wang, Xiaoyun Wu, Neil Wishart
  • KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY
    Publication number: 20140161732
    Abstract: The present invention provides polypeptides, peptide dimers, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides, particularly contrast agents. Also provided are methods for monitoring and evaluating the therapeutic effectiveness of treatment protocols for diseases associated with angiogenesis or endothelial cell hyperproliferation, such as cancer, using contrast agents of the invention.
    Type: Application
    Filed: November 20, 2013
    Publication date: June 12, 2014
    Applicant: Bracco Suisse S.A.
    Inventors: Christophe ARBOGAST, Philippe Bussat, Hong (Helen) Fan, Sudha Khurana, Karen E. Linder, Edmund R. Marinelli, Palaniappa Nanjappan, Adrian D. Nunn, Radhakrishna K. Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf E. Swenson, Mathew A. Von Wronski, Feng Yan
  • Non-Linear Stiffness Roller Assembly
    Publication number: 20140069746
    Abstract: A roller apparatus is provided. The roller apparatus may include a bearing wheel configured to rotatably couple the roller apparatus to a roller shaft, and a resilient member radially disposed about the bearing wheel and configured to contact a guiderail at different magnitudes of loads. The resilient member may include a first section of a first diameter and a second section of a second diameter. The first section may be caused to deflect in response to loads within a first load range, while the second section may be caused to deflect in response to loads within a second load range. The resilient member may exhibit a stepwise increase in stiffness with a gradual increase in load.
    Type: Application
    Filed: May 27, 2011
    Publication date: March 13, 2014
    Applicant: Otis Elevator Company
    Inventors: Richard N. Fargo, Brad Guilani, James L. Hubbard, Adrian D. West
  • PLANARIZATION OF GaN BY PHOTORESIST TECHNIQUE USING AN INDUCTIVELY COUPLED PLASMA
    Publication number: 20140061861
    Abstract: Films of III-nitride for semiconductor device growth are planarized using an etch-back method. The method includes coating a III-nitride surface having surface roughness features in the micron range with a sacrificial planarization material such as an appropriately chosen photoresist. The sacrificial planarization material is then etched together with the III-nitride roughness features using dry etch methods such as inductively coupled plasma reactive ion etching. By closely matching the etch rates of the sacrificial planarization material and the III-nitride material, a planarized III-nitride surface is achieved. The etch-back process together with a high temperature annealing process yields a planarized III-nitride surface with surface roughness features reduced to the nm range. Planarized III-nitride, e.g., GaN, substrates and devices containing them are also provided.
    Type: Application
    Filed: September 4, 2012
    Publication date: March 6, 2014
    Inventors: Theodore D. Moustakas, Adrian D. Williams
  • Multivalent constructs for therapeutic and diagnostic applications
    Patent number: 8663603
    Abstract: The invention provides compositions and methods for therapeutic and diagnostic applications.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: March 4, 2014
    Assignees: Bracco Suisse SA, Dyax Corp.
    Inventors: Christophe Arbogast, Philippe Bussat, Hong Fan, Karen E. Linder, Edmund R. Marinelli, Palaniappa Nanjappan, Adrian D. Nunn, Radhakrishna K. Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf E. Swenson, Mathew A. Von Wronski, Feng Yan, Aaron K. Sato, Sharon Michele Walker, Daniel T. Dransfield
  • 5-substituted indazoles as kinase inhibitors
    Patent number: 8648069
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R1, R2, R3 and m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), Cdc7, AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: February 11, 2014
    Assignee: AbbVie Inc.
    Inventors: Irini Akritopoulou-Zanze, Brian D. Wakefield, Helmut Mack, Sean C. Turner, Alan F. Gasiecki, Vijaya J. Gracias, Kathy A. Sarris, Douglas M. Kalvin, Melissa J. Michmerhuizen, Qi Shuai, Jyoti R. Patel, Margaretha Bakker, Nicole Teusch, Eric F. Johnson, Peter J. Kovar, Stevan W. Djuric, Andrew J. Long, Anil Vasudevan, Dawn George, Lu Wang, Biqin Li, N. St. John Moore, Adrian D. Hobson, Keith W. Woods, Julie M. Miyashiro, Steven L. Swann, Jr., Thomas D. Penning
  • KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
    Patent number: 8642010
    Abstract: The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: February 4, 2014
    Assignees: Dyax Corp., Bracco Suisse SA
    Inventors: Aaron K. Sato, Daniel J. Sexton, Daniel T. Dransfield, Robert C. Ladner, Christophe Arbogast, Philippe Bussat, Hong Fan, Sudha Khurana, Karen E. Linder, Edmund R. Marinelli, Palaniappa Nanjappan, Adrian D. Nunn, Radhakrishna K. Pillai, Sibylle Pochon, Feng Yan, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf E. Swenson, Mathew A. Von Wronski
  • Multivalent constructs for therapeutic and diagnostic applications
    Patent number: 8632753
    Abstract: The invention provides compositions and methods for therapeutic and diagnostic applications.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: January 21, 2014
    Assignees: Bracco Suisse SA, Dyax Corp.
    Inventors: Hong Fan, Karen E. Linder, Edmund R. Marinelli, Palaniappa Nanjappan, Adrian D. Nunn, Radhakrishna K. Pillai, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf E. Swenson, Mathew A. Von Wronski, Aaron K. Sato, Sharon Michele Walker, Daniel T. Dransfield
  • KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
    Patent number: 8623822
    Abstract: The present invention provides polypeptides, peptide dimers, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 ?M), and dimer and multimeric constructs comprising these polypeptides, particularly contrast agents. Also provided are methods for monitoring and evaluating the therapeutic effectiveness of treatment protocols for diseases associated with angiogenesis or endothelial cell hyperproliferation, such as cancer, using contrast agents of the invention.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: January 7, 2014
    Assignee: Bracco Suisse SA
    Inventors: Christophe Arbogast, Philippe Bussat, Hong Fan, Sudha Khurana, Karen E. Linder, Edmund R. Marinelli, Palaniappa Nanjappan, Adrian D. Nunn, Radhakrishna K. Pillai, Sibylle Pochon, Kondareddiar Ramalingam, Ajay Shrivastava, Bo Song, Rolf E. Swenson, Mathew A. Von Wronski, Feng Yan
  • Scalable publish/subscribe messaging systems and methods
    Patent number: 8566423
    Abstract: A publish/subscribe messaging network in which a distributed set of publish/subscribe brokers comprises a first subset of publish/subscribe brokers, each arranged to store proxy subscription information for the whole of the distributed set of brokers; and a second subset of publish/subscribe brokers, each configured to send subscription information for local subscribers to one or more brokers within the first subset of publish/subscribe brokers, and configured to request, from a broker within the first subset of brokers, proxy subscription information following receipt of a message.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: October 22, 2013
    Assignee: International Business Machines Corporation
    Inventors: Andrew D. Banks, Gavin D. Beardall, Adrian D. Dick, Ian C. Vanstone
  • Validating a variable data item in a software routine
    Patent number: 8549488
    Abstract: An apparatus for validating a value of a variable data item in a software routine in execution includes a profile set generator that generates a profile set of typical values of the variable data item, a profile rule generator that generates a profile rule representing the profile set, and a profile checker that determines if a value of the variable data item satisfies the profile rule.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 1, 2013
    Assignee: International Business Machines Corporation
    Inventors: Adrian D. Dick, Gordon D. Hutchison, Clive R. Kates
  • GASTRIN RELEASING PEPTIDE COMPOUNDS
    Publication number: 20130136691
    Abstract: Methods and compositions for diagnosing, staging disease, monitoring therapeutic effect of drugs and imaging a patient are provided, including radiopharmaceutical formulations. Compositions comprising Ga-AMBA complexed with a radioactive isotope are provided; as are methods of imaging Gastrin Releasing Peptide receptor (GRP-R) bearing tissue and methods of diagnosing or staging disease in patients suspected of having disease associated with aberrant GRP-R function. Further, methods of monitoring therapeutic effect of a drug targeted to a receptor that crosstalks with GRP-R are provided; as are methods of pre-dosing/co-dosing non-target tissues containing GRP-R.
    Type: Application
    Filed: May 19, 2009
    Publication date: May 30, 2013
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Adrian D. Nunn, Laura Lantry