Patents by Inventor Akihiro Itoh

Akihiro Itoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230183283
    Abstract: The present invention aims to provide a method of producing, more efficiently at a high purity, a phosphoramidite preferable for the production (synthesis) of a nucleic acid. Using a coupling reaction of an ether represented by the following chemical formula (105), an enantiomer, tautomer or stereoisomer thereof, or a salt thereof, and a glycoside compound, phosphoramidite that enables efficient synthesis of nucleic acid can be obtained: wherein n is a positive integer, and R and R? are the same or different and each is a hydrogen atom or a hydroxyl-protecting group.
    Type: Application
    Filed: October 13, 2017
    Publication date: June 15, 2023
    Applicant: BONAC CORPORATION
    Inventors: Tadaaki OHGI, Eriko AOKI, Takashi KINOSHITA, Akihiro ITOH, Chisato EMURA
  • Patent number: 10377788
    Abstract: The invention provides a production method of a glycoside compound or a salt thereof, which includes subjecting a thioether compound and an alcohol compound to a coupling reaction in the presence of a halogenating agent, a desiccant and a Lewis acid, and then distillation in the presence of at least one kind of additive selected from a sulfur-containing antioxidant and a maleimide group-containing compound to give a thioether compound and a step of subjecting a glycoside compound and a thioether compound to a coupling reaction in the presence of a halogenating agent, a desiccant and a Lewis acid to give a glycoside compound. By this method, a phosphoramidite preferable for the production (synthesis) of a nucleic acid can be produced more efficiently at a high purity.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: August 13, 2019
    Assignee: BONAC CORPORATION
    Inventors: Eriko Aoki, Takashi Kinoshita, Akihiro Itoh, Tadaaki Ohgi
  • Patent number: 9988415
    Abstract: The invention provides a glucoside compound, which is capable of providing a phosphoramidite, which can be produced at low cost and can produce a nucleic acid in high yield and with high purity. The glycoside compound has the formula wherein B, R1, R2, and R3 are as described herein.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: June 5, 2018
    Assignee: BONAC CORPORATION
    Inventors: Eriko Aoki, Hiroshi Suzuki, Akihiro Itoh
  • Patent number: 9941437
    Abstract: A solar cell has a condenser lens and a solar cell element, the solar cell element including an n-type InGaAs layer, an n-type GaAs layer, an n-type InGaP layer, the first InGaAs peripheral part having a thickness (d2), and a width (w2), the second InGaAs peripheral part having a thickness (d3), and a width (w3), the first GaAs peripheral part having a thickness (d5), and a width (w4), the second GaAs peripheral part a thickness (d6), and a width (w5), the first InGaP peripheral part having a thickness (d8), and a width (w6), the second InGaP peripheral part having a thickness (d9), and a width (w7), the following inequation set being satisfied: 1 nm?(d2, d3, d5, and d6)?4 nm, 1 nm?(d8 and d9)?5 nm, 100 nm?(w2, w3, w4, w5, w6, and w7), the InGaAs center part having a thickness (w1), a window layer has a range S irradiated by sunlight having a width (w8); w8?w1.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: April 10, 2018
    Assignee: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.
    Inventors: Akio Matsushita, Akihiro Itoh, Tohru Nakagawa, Hidetoshi Ishida
  • Publication number: 20180079768
    Abstract: The invention provides a production method of a glycoside compound or a salt thereof, which includes subjecting a thioether compound and an alcohol compound to a coupling reaction in the presence of a halogenating agent, a desiccant and a Lewis acid, and then distillation in the presence of at least one kind of additive selected from a sulfur-containing antioxidant and a maleimide group-containing compound to give a thioether compound and a step of subjecting a glycoside compound and a thioether compound to a coupling reaction in the presence of a halogenating agent, a desiccant and a Lewis acid to give a glycoside compound. By this method, a phosphoramidite preferable for the production (synthesis) of a nucleic acid can be produced more efficiently at a high purity.
    Type: Application
    Filed: April 1, 2016
    Publication date: March 22, 2018
    Applicant: BONAC CORPORATION
    Inventors: Eriko AOKI, Takashi KINOSHITA, Akihiro ITOH, Tadaaki OHGI
  • Patent number: 9542468
    Abstract: Data synchronization requires much time if synchronization is started from an initial state where synchronization between databases is not performed, and when a synchronized record is updated during the synchronization process, synchronization of records must be performed again, so that the amount of communication for synchronization is increased. Therefore, when starting synchronization, data synchronization is performed based on a method using a table indicating the synchronization statuses between databases, and at the final stage of synchronization, data synchronization is performed based on a query transmission method using update logs.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: January 10, 2017
    Assignee: Hitachi, Ltd.
    Inventor: Akihiro Itoh
  • Publication number: 20160329903
    Abstract: An atomic oscillator includes a gas cell and a plurality of components. The plurality of components includes a temperature control device for the gas cell; an excitation light source that emits excitation light to excite atoms enclosed in the gas cell; a temperature control device for the excitation light source; and a light receiving element that detects the excitation light that passes through the gas cell. The plurality of components is mounted on an insulating film having wiring.
    Type: Application
    Filed: January 26, 2015
    Publication date: November 10, 2016
    Applicant: RICOH COMPANY, LTD
    Inventors: Kazuhiko ADACHI, Kazuhiro HARASAKA, Akihiro ITOH
  • Patent number: 9481702
    Abstract: The invention provides a glucoside compound, which is capable of providing a phosphoramidite, which can be produced at low cost and can produce a nucleic acid in high yield and with high purity. The glycoside compound has the formula wherein B, R1, and R2 are as described herein, R3 is —OCH2(OCH2)n—O-L1-[D1], in which L1 is an ethylene group, wherein hydrogen atoms besides a hydrogen atom bonded to the ?-position relative to [D1] are optionally substituted by a straight chain or branched alkyl group, n is a positive integer, and [D1] is an electron-withdrawing group.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: November 1, 2016
    Assignee: Bonac Corporation
    Inventors: Eriko Aoki, Hiroshi Suzuki, Akihiro Itoh
  • Patent number: 9470434
    Abstract: Provided is a multiplex pipe and a system for recovering steam from a geothermal well, which are capable of solving all of the various problems with a neutralization pipe prepared by painting or the like of an alkali-resistant coating on the inner face of an acid-resistant single pipe. A multiplex pipe 10 that is configured to recover steam from a geothermal well GT, includes: a casing pipe 1 located outside; and a duplex pipe 4 that is slidable relative to the casing pipe 1 in the casing pipe 1, and has a first gap 5 with an inner face of the casing pipe 1, the duplex pipe including an outer pipe 2 having acid-resistance and an inner pipe 3 having alkali-resistance, the outer pipe 2 and the inner pipe 3 defining a second gap 6 therebetween.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: October 18, 2016
    Assignee: Nippon Steel & Sumikin Engineering Co., Ltd.
    Inventors: Keita Suzumura, Masayuki Igarashi, Akihiro Itoh, Akira Kawakami, Hideki Fujii, Teruhiko Hayashi, Kazuhiro Takahashi
  • Publication number: 20160259837
    Abstract: Data synchronization requires much time if synchronization is started from an initial state where synchronization between databases is not performed, and when a synchronized record is updated during the synchronization process, synchronization of records must be performed again, so that the amount of communication for synchronization is increased. Therefore, when starting synchronization, data synchronization is performed based on a method using a table indicating the synchronization statuses between databases, and at the final stage of synchronization, data synchronization is performed based on a query transmission method using update logs.
    Type: Application
    Filed: March 24, 2014
    Publication date: September 8, 2016
    Applicant: Hitachi, Ltd.
    Inventor: Akihiro ITOH
  • Publication number: 20160176810
    Abstract: The invention provides a glucoside compound, which is capable of providing a phosphoramidite, which can be produced at low cost and can produce a nucleic acid in high yield and with high purity. The glycoside compound has the formula wherein B, R1, R2, and R3 are as described herein.
    Type: Application
    Filed: March 3, 2016
    Publication date: June 23, 2016
    Applicant: BONAC CORPORATION
    Inventors: Eriko AOKI, Hiroshi SUZUKI, Akihiro ITOH
  • Publication number: 20160108400
    Abstract: Provided is a novel nucleic acid molecule that is a single-stranded nucleic acid molecule including an expression inhibitory sequence that inhibits expression of a target gene. The single-stranded nucleic acid molecule includes, in sequence from the 5? side to the 3? side: a 5? side region (Xc); an inner region (Z); and a 3? side region (Yc). The inner region (Z) is composed of an inner 5? side region (X) and an inner 3? side region (Y) that are linked to each other. The 5? side region (Xc) is complementary to the inner 5? side region (X). The 3? side region (Yc) is complementary to the inner 3? side region (Y). At least one of the inner region (Z), the 5? side region (Xc), and the 3? side region (Yc) includes the expression inhibitory sequence.
    Type: Application
    Filed: October 29, 2015
    Publication date: April 21, 2016
    Applicant: BONAC CORPORATION
    Inventors: Tadaaki Ohgi, Hirotake Hayashi, Hisao Shirohzu, Tomohiro Hamasaki, Akihiro Itoh, Hiroshi Suzuki
  • Patent number: 9206422
    Abstract: Provided is a novel nucleic acid molecule that can be produced easily and efficiently and can inhibit the expression of a gene. The nucleic acid molecule is a single-stranded nucleic acid molecule including an expression inhibitory sequence that inhibits expression of a target gene. The single-stranded nucleic acid molecule includes: a region (X); a linker region (Lx); and a region (Xc). The linker region (Lx) is linked between the regions (Xc) and (Xc). The region (Xc) is complementary to the region (X). At least one of the regions (X) and (Xc) includes the expression inhibitory sequence. The linker region (Lx) has a non-nucleotide structure including at least one of a pyrrolidine skeleton and a piperidine skeleton. According to this single-stranded nucleic acid molecule, it is possible to inhibit the expression of the target gene.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: December 8, 2015
    Assignee: BONAC Corporation
    Inventors: Tadaaki Ohgi, Hirotake Hayashi, Hisao Shirohzu, Tomohiro Hamasaki, Akihiro Itoh, Hiroshi Suzuki
  • Patent number: 9201404
    Abstract: An alkali metal cell is disclosed, including a substrate in which is formed an opening which penetrates from one face to the other face thereof; a first transparent substrate bonded to the other face of the substrate; and a second transparent substrate bonded to the one face of the substrate, wherein an alkali metal is sealed into a space surrounded by the first transparent substrate and the second transparent substrate in the opening of the substrate, wherein, in the substrate and the second transparent substrate, the space is enclosed by a bonding between a first bonding metal layer formed by a first bonding metal and a second bonding metal layer formed by a second bonding metal, and wherein the second bonding metal layer has a bonding temperature higher than that of the first bonding metal layer.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: December 1, 2015
    Assignee: RICOH COMPANY, LTD.
    Inventors: Kazuhiro Harasaka, Kazuhiko Adachi, Hiroyoshi Shouji, Akihiro Itoh, Shunichi Sato, Shinji Satoh
  • Patent number: 9200278
    Abstract: Provided is a novel nucleic acid molecule that can be produced easily and efficiently and can inhibit the expression of a gene. The nucleic acid molecule is a single-stranded nucleic acid molecule including an expression inhibitory sequence that inhibits expression of a target gene. The single-stranded nucleic acid molecule includes: a region (X); a linker region (Lx); and a region (Xc). The linker region (Lx) is linked between the regions (Xc) and (Xc). The region (Xc) is complementary to the region (X). At least one of the regions (X) and (Xc) includes the expression inhibitory sequence. The linker region (Lx) has a non-nucleotide structure including at least one of a pyrrolidine skeleton and a piperidine skeleton. According to this single-stranded nucleic acid molecule, it is possible to inhibit the expression of the target gene.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: December 1, 2015
    Assignee: BONAC Corporation
    Inventors: Tadaaki Ohgi, Hirotake Hayashi, Hisao Shirohzu, Tomohiro Hamasaki, Akihiro Itoh, Hiroshi Suzuki
  • Patent number: 9176417
    Abstract: A surface-emitting laser device includes a transparent dielectric layer provided in an emitting region and configured to cause a reflectance at a peripheral part to be different from a reflectance at a central part in the emitting region. In the surface-emitting laser device, the thickness of a contact layer is different between a region having a relatively high reflectance and a region having a relatively low reflectance in the emitting region. The contact layer is provided on the high refractive index layer of an upper multilayer film reflecting mirror, and the total optical thickness of the high refractive index layer and the contact layer in the region having the relatively low reflectance is deviated from an odd number multiple of a one quarter oscillation wavelength of laser light emitted from the emitting region.
    Type: Grant
    Filed: April 4, 2014
    Date of Patent: November 3, 2015
    Assignee: RICOH COMPANY, LTD.
    Inventors: Kazuhiro Harasaka, Shunichi Sato, Masahiro Hayashi, Akihiro Itoh, Katsunari Hanaoka
  • Publication number: 20150226463
    Abstract: Provided is a multiplex pipe and a system for recovering steam from a geothermal well, which are capable of solving all of the various problems with a neutralization pipe prepared by painting or the like of an alkali-resistant coating on the inner face of an acid-resistant single pipe. A multiplex pipe 10 that is configured to recover steam from a geothermal well GT, includes: a casing pipe 1 located outside; and a duplex pipe 4 that is slidable relative to the casing pipe 1 in the casing pipe 1, and has a first gap 5 with an inner face of the casing pipe 1, the duplex pipe including an outer pipe 2 having acid-resistance and an inner pipe 3 having alkali-resistance, the outer pipe 2 and the inner pipe 3 defining a second gap 6 therebetween.
    Type: Application
    Filed: May 28, 2013
    Publication date: August 13, 2015
    Applicants: Nippon Steel & Sumikin Engineering Co., Ltd., Nippon Steel & Sumitomo Metal Corporation
    Inventors: Keita Suzumura, Masayuki Igarashi, Akihiro Itoh, Akira Kawakami, Hideki Fujii, Teruhiko Hayashi, Kazuhiro Takahashi
  • Publication number: 20150213564
    Abstract: Provided is a consumer cooperation support system in which control requests from a plurality of master consumers do not conflict with each other. A consumer cooperation support apparatus collects attribute information from an EMS group that can collect, manage, and transmit attribute information of ordinary power consumers, and manages the attribute information to manage an identifier of a master consumer EMS group that issues a control request to other consumers by its own judgment. The consumer cooperation support apparatus allocates a cluster obtained by classifying consumers based on the attribute information to a group created so as to correspond to the master consumer EMS. When the master consumer EMS refers to an EMS group in order to issues a control request, the EMS group that can be referred to is limited to EMSs included in the group.
    Type: Application
    Filed: August 27, 2012
    Publication date: July 30, 2015
    Applicant: Hitachi, Ltd.
    Inventors: Haruhisa Ishida, Hiroyuki Hori, Akihiro Itoh, Takashi Noguchi
  • Publication number: 20150099623
    Abstract: The present invention provides an oxide film composed of an oxide having a perovskite crystal structure. The oxide is represented by a chemical formula A1-x(E1-yGy)Oz. A represents at least one element selected from the group consisting of Ba, Sr, and Ca. E represents at least one element selected from the group consisting of Zr, Hf, In, Ga, and Al. G represents at least one element selected from the group consisting of Y, La, Ce, and Gd. All of the following five mathematical formulae are satisfied: 0.2?x?0.5, 0.1?y?0.7, z<3, 0.3890 nanometers?a?0.4190 nanometers, 0.95?a/c<0.98. Each of a, b and c represents a lattice constant of the perovskite crystal structure. Either the following mathematical formula is satisfied: a?b<c or a<b?c.
    Type: Application
    Filed: September 29, 2014
    Publication date: April 9, 2015
    Inventors: TAKASHI NISHIHARA, YUJI ZENITANI, TETSUYA ASANO, AKIHIRO ITOH, TOMOYUKI KOMORI, HIDEAKI ADACHI, EIJI FUJII
  • Patent number: 8970309
    Abstract: An atomic oscillator is disclosed, including an Alkaline metal cell, a light source illuminating a laser beam to the Alkaline metal cell, and a light detector detecting light passing through the Alkaline metal cell. The Alkaline metal cell includes a first member, a second member, a cell internal portion, and an Alkaline metal raw material. In the first member, a first glass substrate is bonded on a second surface of a first substrate where a first opening part is formed. In the second member, a second glass substrate is bonded to a fourth surface of a second substrate where a second opening part is formed. The cell internal portion is formed by the first opening part and the second opening part by bonding the first surface to the third surface. The Alkaline metal raw material is enclosed by the cell internal portion.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: March 3, 2015
    Assignee: Ricoh Company, Ltd.
    Inventors: Shunichi Sato, Akihiro Itoh, Yukito Sato