Abstract: The present invention provides a novel cancer marker for testing a morbidity risk of a cancer. The cancer marker according to the present invention is a prorenin receptor. A test method for testing a morbidity risk of a cancer according to the present invention includes measuring a prorenin receptor expression in a biological specimen obtained from a subject and further includes, for example, a step of comparing a prorenin receptor expression level in the biological specimen obtained from the subject with a reference value to test the morbidity risk of the cancer in the subject. The reference value is a prorenin receptor expression level in a biological specimen obtained from a healthy subject or a cancer patient. When the expression level in the subject is higher than that in the healthy subject or identical to or higher than that in the cancer patient, it can be evaluated that the subject has the mobility risk of the cancer.

Abstract: A cyclic amine compound having a prescribed configuration can be efficiently prepared by reducing an imine derivative in the presence of a sulfonic acid. Specifically, a cyclic amine compound which is substituted with an amino group and a carboxyl group in which both groups are arranged in the trans configuration can be prepared efficiently.

Abstract: A first ink air chamber is in communication with an air layer in a first ink tank for an ink of a first viscosity in communication with a first inkjet head. A second ink air chamber is in communication with an air layer in a second ink tank for an ink of a second viscosity in communication with a second inkjet head. A first on-off valve opens or closes communication between the first and second ink air chambers. A second on-off valve opens or closes communication between the second ink air chamber and the atmosphere. A pressure adjuster is configured to adjust a pressure in the second ink air chamber without intervention of the first ink air chamber. A controller is configured to drive the pressure adjuster to increase the pressure in the second ink air chamber with the first and second on-off valves being closed.

Abstract: The present invention relates to a method for producing an optically active 3-aminopiperidine or salt thereof. In the method, a racemic nipecotamide is stereoselectively hydrolyzed to obtain an optically active nipecotamide and an optically active nipecotic acid in the presence of an enzyme source derived from an organism, and then the optically active nipecotamide is derived into an optically active aminopiperidine or salt thereof by aroylation, Hofmann rearrangement, deprotection of the amino group and further deprotection; or the optically active nipecotamide is derived into an optically active aminopiperidine or salt thereof by selective protection with BOC, Hofmann rearrangement and further deprotection. It is possible by the present invention to produce an optically active 3-aminopiperidine or salt thereof useful as a pharmaceutical intermediate from an inexpensive and easily available starting material by easy method applicable to industrial manufacturing.

Abstract: A determiner determines whether a total ink amount in an ink circulation passage calculated by an ink amount calculator is less than an ink circulation necessary amount being an amount necessary for circulation of ink in the ink circulation passage, when a liquid level detector detects that a liquid level of the ink in an ink tank is lower than a liquid level corresponding to an ink circulation standard amount being a standard for ink circulation. A controller performs ink supply amount control to supply the ink from an ink bottle to the ink tank in such an amount that the total ink amount is kept below the ink circulation standard amount, when the determiner determines that the total ink amount is less than the ink circulation necessary amount.

Abstract: A first ink air chamber is in communication with an air layer in a first ink tank for an ink of a first viscosity in communication with a first inkjet head. A second ink air chamber is in communication with an air layer in a second ink tank for an ink of a second viscosity in communication with a second inkjet head. A first on-off valve opens or closes communication between the first and second ink air chambers. A second on-off valve opens or closes communication between the second ink air chamber and the atmosphere. A pressure adjuster is configured to adjust a pressure in the second ink air chamber without intervention of the first ink air chamber. A controller is configured to drive the pressure adjuster to increase the pressure in the second ink air chamber with the first and second on-off valves being closed.

Abstract: A determiner determines whether a total ink amount in an ink circulation passage calculated by an ink amount calculator is less than an ink circulation necessary amount being an amount necessary for circulation of ink in the ink circulation passage, when a liquid level detector detects that a liquid level of the ink in an ink tank is lower than a liquid level corresponding to an ink circulation standard amount being a standard for ink circulation. A controller performs ink supply amount control to supply the ink from an ink bottle to the ink tank in such an amount that the total ink amount is kept below the ink circulation standard amount, when the determiner determines that the total ink amount is less than the ink circulation necessary amount.

Abstract: The problem to be solved by the present invention is to ea lily and efficiently produce an amino acid having 2 to 7 carbon atoms as a high-purity solid without complicated operation, which is useful as a synthetic intermediate for medicines or agrochemicals. The present invention is characterized in comprising a step of precipitating solid amino acid with high purity. In the present invention, the by-produced salt composed of the sulfonic acid and the amine was removed to the mother liquor by reacting an amine with a sulfonic acid salt of amino acid in an aprotic polar solvent, or by reacting a sulfonic acid with an amine salt of amino acid in an aprotic polar solvent. The sulfonic acid salt of amino acid, for example, may be produced by reacting a N-(tert-butoxycarbonyl) amino acid with a sulfonic acid, or by reacting an amino acid tert-butyl ester with a sulfonic acid.

Abstract: An image forming machine includes an image data memory, an image data mapper, and a printer. For an envelope, the image data memory stores image data to be printed on a back of the body and a face of the flap, as backside image data. Based on this data, the image data mapper generates print data including a first print data to be printed on the body back and a second print data to be printed on the flap face. The printer prints a part of the backside image data on the body back in accordance with the first print data, and a remaining part of the backside image data on the flap face in accordance with the second print data.

Abstract: An envelope warpage correcting device includes a sheet feeding portion, a correction means and a control portion. The sheet feeding portion feeds envelopes one-by-one in a state where the envelopes are stacked on a sheet feed table and a rear end portion opposite to a flap portion formed in a front end portion of each of the envelopes is set to a leading portion in a sheet feed direction. The correction means corrects warpage occurring at a side of the rear end portion of the envelope fed by the sheet feeding portion. The control portion controls processing for correcting the warpage occurring at the side of the rear end portion by the correcting portion at certain timing according to an attribution of the envelope.

Abstract: Captured or input image data is converted into an image of a size of a specific number of pixels. Then, predetermined plural types of different effects are applied to image data obtained through the conversion. Several types of image data items with the applied effects are arranged and simultaneously displayed.

Abstract: A cyclic amine compound having a prescribed configuration can be efficiently prepared by reducing an imine derivative in the presence of a sulfonic acid. Specifically, a cyclic amine compound which is substituted with an amino group and a carboxyl group in which both groups are arranged in the trans configuration can be prepared efficiently.

Abstract: A video receiving apparatus having an input terminal to receive pixel-based video data transmitted with pixel clock synchronized with the video data is provided. The video receiving apparatus may include a separation unit, an information acquisition unit, and a determination unit. The separation unit may be configured to separate auxiliary data added to the video data from the video data obtained at the input terminal. The information acquisition unit may be configured to acquire information on the number of horizontal pixels and the number of vertical pixels for the input video data from the auxiliary data separated at the separation unit. The determination unit may be configured to determine a type of the input video data based on the information on the number of horizontal pixels and the number of vertical pixels that is obtained at the information acquisition unit.

Abstract: The present invention relates to a method for producing an optically active 3-aminopiperidine or salt thereof. In the method, a racemic nipecotamide is stereoselectively hydrolyzed to obtain an optically active nipecotamide and an optically active nipecotic acid in the presence of an enzyme source derived from an organism, and then the optically active nipecotamide is derived into an optically active aminopiperidine or salt thereof by aroylation, Hofmann rearrangement, deprotection of the amino group and further deprotection; or the optically active nipecotamide is derived into an optically active aminopiperidine or salt thereof by selective protection with BOC, Hofmann rearrangement and further deprotection. It is possible by the present invention to produce an optically active 3-aminopiperidine or salt thereof useful as a pharmaceutical intermediate from an inexpensive and easily available starting material by easy method applicable to industrial manufacturing.

Abstract: A semiconductor device includes a semiconductor substrate, an nMISFET formed on the substrate, the nMISFET including a first dielectric formed on the substrate and a first metal gate electrode formed on the first dielectric and formed of one metal element selected from Ti, Zr, Hf, Ta, Sc, Y, a lanthanoide and actinide series and of one selected from boride, silicide and germanide compounds of the one metal element, and a pMISFET formed on the substrate, the pMISFET including a second dielectric formed on the substrate and a second metal gate electrode formed on the second dielectric and made of the same material as that of the first metal gate electrode, at least a portion of the second dielectric facing the second metal gate electrode being made of an insulating material different from that of at least a portion of the first dielectric facing the first metal gate electrode.

Abstract: The objective of the present invention is to produce an optically active 2-arylpiperazine derivative useful as a synthetic intermediate for pharmaceutical products and agricultural chemicals from inexpensive and readily available starting material by an industrially practicable method. The objective can be accomplished by treating an optically active substituted aminodiol derivative produced from an optically active styrene oxide derivative with a sulfonating agent in the presence of a base, and then reacting an amine compound to obtain the 2-arylpiperazine derivative. Especially, an optically active 1-unsubstituted-2-arylpiperazine derivative can be produced by treating an optically active 1-allyl-2-arylpiperazine derivative with water in the presence of a transition metal catalyst for deallylation.

Abstract: An image forming machine includes an image data memory, an image data mapper, and a printer. For an envelope, the image data memory stores image data to be printed on a back of the body and a face of the flap, as backside image data. Based on this data, the image data mapper generates print data including a first print data to be printed on the body back and a second print data to be printed on the flap face. The printer prints a part of the backside image data on the body back in accordance with the first print data, and a remaining part of the backside image data on the flap face in accordance with the second print data.

Abstract: An envelope warpage correcting device includes a sheet feeding portion, a correction means and a control portion. The sheet feeding portion feeds envelopes one-by-one in a state where the envelopes are stacked on a sheet feed table and a rear end portion opposite to a flap portion formed in a front end portion of each of the envelopes is set to a leading portion in a sheet feed direction. The correction means corrects warpage occurring at a side of the rear end portion of the envelope fed by the sheet feeding portion. The control portion controls processing for correcting the warpage occurring at the side of the rear end portion by the correcting portion at certain timing according to an attribution of the envelope.

Abstract: A semiconductor device includes a semiconductor substrate, an nMISFET formed on the substrate, the nMISFET including a first dielectric formed on the substrate and a first metal gate electrode formed on the first dielectric and formed of one metal element selected from Ti, Zr, Hf, Ta, Sc, Y, a lanthanoide and actinide series and of one selected from boride, silicide and germanide compounds of the one metal element, and a pMISFET formed on the substrate, the pMISFET including a second dielectric formed on the substrate and a second metal gate electrode formed on the second dielectric and made of the same material as that of the first metal gate electrode, at least a portion of the second dielectric facing the second metal gate electrode being made of an insulating material different from that of at least a portion of the first dielectric facing the first metal gate electrode.

Abstract: A nonvolatile semiconductor memory apparatus includes: a source and drain regions formed at a distance from each other in a semiconductor layer; a first insulating film formed on the semiconductor layer located between the source region and the drain region, the first insulating film including a first insulating layer and a second insulating layer formed on the first insulating layer and having a higher dielectric constant than the first insulating layer, the second insulating layer having a first site performing hole trapping and releasing, the first site being formed by adding an element different from a base material to the second insulating film, the first site being located at a lower level than a Fermi level of a material forming the semiconductor layer; a charge storage film formed on the first insulating film; a second insulating film formed on the charge storage film; and a control gate electrode formed on the second insulating film.