Abstract: Methods for forming rosin-derived cationic compounds are provided. The method can include attaching a cationic group to a conjugated diene on a hydrophenathrene-based ring of a resin acid (e.g., levopimaric acid, abietic acid, dehydroabietic acid, or a mixture thereof) to form a rosin-derived cationic compound. Attaching the cationic group to the conjugated diene on the hydrophenathrene-based ring of the resin acid can be achieved via a Diels-Alder reaction of a dienophile with the hydrophenathrene-based ring of the resin acid. Rosin-derived cationic compounds are also provided. The rosin-derived cationic compound can include a cationic group attached to a conjugated diene on a hydrophenathrene-based ring of a resin acid, wherein the rosin-derived cationic compound further comprises a carboxylic acid group.

Abstract: Methods of stimulating or enhancing an immune response in a host are disclosed. The methods include contacting a monocyte with 15 kD granulysin thereby producing a monocyte-derived dendritic cell. In one example, the method further includes contacting the monocyte or monocyte-derived dendritic cell with a target antigen, such as a tumor antigen or an autoimmune antigen. In another embodiment, the method includes contacting the monocyte with an additional agent that enhances maturation of dendritic cells or induces immunological tolerance. The methods are of use in vivo, in vitro and ex vivo. In another aspect, the disclosure relates to compositions and methods for the treatment of tumors.

Abstract: A system and method for facilitating the accurate entry of information into a highly structured database by initially extracting information from a plurality of nonuniformly formatted source data streams, e.g., documents/files, and subsequent interactions with users before storing the accepted and/or modified information into the database. Embodiments of the present invention provide an interactive path for each user (e.g., the author of the source document/file) to interactively modify the extracted data, e.g., according to the source document/file. Preferably, this interactive path is provided via the Internet and the extracted information can be modified by editing and/or selectively copying portions of the source documents/files to supplement and/or modify the extracted information.

Abstract: In accordance with the present invention, there is provided a semiconductor package wherein a metal lid of the package is used as a shield that effectively surrounds the active circuitry, and thus forms a type of Faraday shield. The lid is electrically coupled to an internal die mounting pad of either a leadframe or an alternative type of substrate. Appropriate interconnect methods between the lid, the die pad, and the ground connections exterior to the semiconductor package include, but are not restricted to, conductive adhesives, wire bonding, bumps, tabs, or similar techniques.

Abstract: A crusher adapted to crush feed materials comprising a main frame, a secondary frame disposed adjacent to the main frame, a crushing chamber adapted to receive feed materials, and a tramp iron relief system comprising a cylinder. The tramp iron relief system is adapted to allow a portion of the secondary frame to move away from the main frame. The cylinder is disposed substantially adjacent to the secondary frame. A method for installing a cylinder on a crusher and a method for removing a cylinder from a crusher wherein a lifting device remains attached to the cylinder continuously during each operation.

Abstract: The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (Ia) or compositions comprising compounds of Structural Formulas (I) and (Ia), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed.

Abstract: A video surveillance system may include at least one sensing unit capable of being operated in a scanning mode and a video processing unit coupled to the sensing unit, the video processing unit to receive and process image data from the sensing unit and to detect scene events and target activity.

Abstract: A clock recovery circuit is provided comprising a receiver circuit and a clock extraction circuit. The receiver circuit may be adapted to decode a differentially encoded signal on a plurality of data lines, where at least one data symbol is differentially encoded in state transitions of the differentially encoded signal. The clock extraction circuit may be adapted to obtain a clock signal from state transition signals derived from the state transitions.

Abstract: A 3D image projector having a translucent rotatable hollow cylinder, the hollow cylinder having differently polarized sections, and the projector being capable of passing a light beam generally orthogonally through a wall of the hollow cylinder is disclosed.

Abstract: A method of allowing listeners to participate in broadcast programming is provided, the method generally comprising one or more of providing a library of media elements accessible by a plurality of listeners; receiving from each of at least two of the listeners a playlist of media elements, wherein at least one of the media elements in each playlist is from the library of media elements; editing the playlists using broadcast scheduling software; providing the edited playlists to the plurality of listeners for playback, and for feedback regarding the playlists; and receiving feedback from at least one of the listeners regarding the playlists. A system and apparatus are similarly provided.

Abstract: Systems, devices, and processes for classifying a digital item are described. In some examples, a first classifier determines whether a digital item, such as an electronic book (eBook), includes content of a first category that is acceptable for publication by a publisher. A second classifier determines whether the digital item includes content of a second category that is acceptable for publication by a publisher. In response to determining that the digital item includes content of the first category or content of the second category, a third classifier may determine whether the digital item includes a phrase that is indicative of content of a third category that is unacceptable for publication.

Abstract: A bottle pouring dispenser featuring a dispenser housing having a lower end configured to be removably attached to and cover an open end of a bottle. The bottle pouring dispenser includes a valve providing one-way hydraulic communication from the bottle to a chamber defined within the dispenser housing. The dispenser housing has upper and lower chamber portions. A flavorant is disposed within the upper chamber portion in solid form and it is dissolvable in liquid so as to add flavoring to liquid flowing through the chamber. The flavorant is held spaced above a floor of the chamber, such that a lower portion of the chamber defines a drain volume beneath the flavorant for receiving liquid draining from about the flavorant. The bottle pouring dispenser further includes a pour spout extending from an upper end of the dispenser housing, for dispensing the flavored liquid from the chamber.

Abstract: Embodiments of this disclosure pertain to articles that exhibit scratch-resistance and improved optical properties. In some examples, the article exhibits a reflection or transmission color shift of about 2 or less, when viewed at an incident illumination angle in the range from about 20 degrees to about 60 degrees from normal under an illuminant and hardness of at least 14 GPa at an indentation depth of at least 100 nm from the surface of the article. In one or more embodiments, the articles include a substrate, and an optical film disposed on the substrate. The optical film includes a scratch-resistant layer and an optical interference layer. The optical interference layer may include one or more sub-layers that exhibit different refractive indices. In one example, the optical interference layer includes a first low refractive index sub-layer, a second a second high refractive index sub-layer, and an optional third sub-layer.

Abstract: A method for designing a system on a target device includes assigning resources on the target device to static logic modules and partial reconfigurable (PR) modules in the system. The instances of one of the PR modules are placed and routed in parallel utilizing resources from those that are assigned. Other embodiments are also disclosed.

Abstract: A hybrid ultrasonic audio system includes one or more ultrasonic speakers and one or more conventional speakers. An optical imaging system may be used to automatically determine the distance of a listener relative to the audio system. Channel processors apply distance-related transfer function filters to one or more of the audio channels based on the determined distances to equalize the amplitude of the audio played by the ultrasonic speakers relative to the conventional speakers. Channel processors may further apply a phase or time delay to the audio channels to match the phase and time delay of the ultrasonic speaker audio to the conventional speaker audio.

Abstract: A reservoir system for an operating unit, such as a humidifier, includes a removable water tank configured to provide the operating unit with water. The removable water tank includes a primary reservoir for holding water, with an opening in the removable water tank fluidically connecting the primary reservoir with a secondary reservoir in the operating unit. A plunger is slidably disposed in the opening and movable between an open position in which the opening fluidically connects the primary reservoir to the secondary reservoir, and a closed position that seals the opening to fluidically disconnect the primary reservoir from the secondary reservoir. A float member in the secondary reservoir includes a buoyant main body and is configured to generate a force upon the plunger to urge the plunger into the open position according to the height of water in the secondary reservoir.

Abstract: The compressor comprises a valve plate, to be affixed to a compressor block, and a suction valve (V) formed by a spacer body, having a median opening and a flexible vane, which has a fixing end portion provided with a contour, symmetrical or asymmetrical, in relation to a longitudinal axis (X) of the flexible vane and which presents peripheral edge portions to be seated against respective inner edge portions of the median opening for restricting coplanar, linear and angular displacements of the flexible vane in relation to the spacer body upon seating the flexible vane against the valve plate, in the interior of the median opening.

Abstract: The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PD-1 with high affinity. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The invention also provides methods for detecting PD-1, as well as methods for treating various diseases, including cancer and infectious diseases, using anti-PD-1 antibodies. The present invention further provides methods for using a combination immunotherapy, such as the combination of anti-CTLA-4 and anti-PD-1 antibodies, to treat hyperproliferative disease, such as cancer. The invention also provides methods for altering adverse events related to treatment with such antibodies individually.