Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.

Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.

Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.

Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.

Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.

Abstract: Methods of treating and preventing metabolic disease through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.

Abstract: Provided are antigen-binding molecules capable of binding to IL-11R?, and methods of medical treatment and prophylaxis using the same.

Abstract: A tuple testing and routing operator in a streaming application routes data tuples to multiple parallel test operators that test in parallel the data tuples, receives feedback from the multiple parallel test operators regarding the results of testing the data tuples, routes a data tuple to a first operator when the data tuple passes the multiple parallel test operators according to a specified pass threshold, and optionally routes the data tuple to a second operator when the data tuple does not pass the multiple parallel test operators according to the specified pass threshold. The pass threshold allows testing to be done in a way that does not require all tests to be performed for all data tuples, thereby enhancing performance.

Abstract: A method, computer program product, and computing device for identifying at least one tuple of interest from a plurality of tuples during execution of a streaming application. A window of tuples including the at least one tuple from the plurality of tuples may be defined. One or more operations may be performed on the window of tuples.

Abstract: Aspects of the disclosure relate to managing a set of warning data with respect to an execution phase in a computing environment. In embodiments, the computing environment may include a distributed computing environment or a stream computing environment. The set of warning data may be detected with respect to the execution phase. In embodiments, the set of warning data may be coupled with a computing artifact. In embodiments, the computing artifact may include a compilation which has a computing object in association with the set of warning data. Using the set of warning data, an execution action which pertains to the computing artifact may be determined. In embodiments, the execution action may include a code deployment to a set of computing units, a run-time check modification, or a process attribute modification. The execution action which pertains to the computing artifact may be performed.

Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.

Abstract: A means and method to ensure the correct installation of a stairlift is provided. An electronic control facility within the stairlift includes an installation mode and a user mode, the installation mode prescribing a number of installation steps that must be undertaken correctly before the user mode can be entered.

Abstract: Methods of treating and preventing kidney injury through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.

Abstract: The invention provides a method and apparatus for continuously adjusting the speed of a stairlift in response to a number of operating parameters such as battery voltage and motor current draw. The method preferably further includes monitoring the speed of a reference point on a stairlift chair and comparing this with a maximum permissible speed.

Abstract: Methods of treating and preventing hepatotoxicity through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.

Abstract: In preventing malicious operator placement in a streaming application, a stream computing management system receives a submission of an operator graph for the streaming application. A scheduler of the stream computing management system places the operators across a plurality of computing nodes. A threat detector of the stream computing management system monitors placements of the operators during the submission of the operator graph and a runtime of the streaming application. The threat detector further monitors runtime activities of the operators of the streaming application. The threat detector compares the runtime activities of the operators of the streaming application with stored activities patterns. The threat detector determines whether any anomalies identified based on the comparing exceeds a risk tolerance threshold. In response to an anomaly exceeding the risk tolerance threshold, the scheduler changes a placement of at least one of the operators.

Abstract: Queries are monitored in a database which receives input from a stream computing application to identify data of interest. Parameters defining the data of interest, which are preferably expressed as a logical query, are sent to the stream computing application, which then processes the in-flight streamed data satisfying the parameters in some special manner. In some embodiments, the stream computing application increases the processing priority of in-flight data satisfying the parameters. In some embodiments, the stream computing application applies additional processing steps to the in-flight data satisfying the parameters to provide enhanced data or metadata.

Abstract: A first set of code origination data which corresponds to a first computing object and a second set of code origination data which corresponds to a second computing object may be detected for utilization to develop a streaming application in the stream computing environment. Based on the first and second sets of code origination data, a code assembly arrangement with respect to the first and second computing objects may be determined. Based on the first and second sets of code origination data, a consistent region may be determined to utilize for the code assembly arrangement. The code assembly arrangement may be established, in the consistent region, with respect to the first and second computing objects to develop the streaming application.

Abstract: IL-11Ra antibodies are disclosed. Also disclosed are compositions comprising the IL-11Ra antibodies, and methods using the IL-11Ra antibodies.

Abstract: IL-11 antibodies are disclosed. Also disclosed are compositions comprising the IL-11 antibodies, and methods using the IL-11 antibodies.