Abstract: The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions, into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent. The invention also provides methods of treating or preventing certain disorders, or symptomatic relief therefrom, by administering the compositions of the invention to a patient, e.g.

Abstract: A method of operating a mobile robot includes generating a segmentation map defining respective regions of a surface based on occupancy data that is collected by a mobile robot responsive to navigation of the surface, identifying sub-regions of at least one of the respective regions as non-clutter and clutter areas, and computing a coverage pattern based on identification of the sub-regions. The coverage pattern indicates a sequence for navigation of the non-clutter and clutter areas, and is provided to the mobile robot. Responsive to the coverage pattern, the mobile robot sequentially navigates the non-clutter and clutter areas of the at least one of the respective regions of the surface in the sequence indicated by the coverage pattern. Related methods, computing devices, and computer program products are also discussed.

Abstract: Systems, apparatuses, and methods for determining preferred memory page management policies by software are disclosed. Software executing on one or more processing units generates a memory request. Software determines the preferred page management policy for the memory request based at least in part on the data access size and data access pattern of the memory request. Software conveys an indication of a preferred page management policy to a memory controller. Then, the memory controller accesses memory for the memory request using the preferred page management policy specified by software.

Abstract: A computer-implemented method to provide information characterizing real-estate market conditions within a geographic sub-region included within a larger geographic region is described herein. An indication of the geographic sub-region is received from a user. A memory device on which is stored information characterizing a set of parcels of real property that have been listed for sale is accessed. A parcel of real property located in the sub-region and for which a purchase offer has been made is identified from the stored information. If a purchase transaction for the parcel of real property has not closed, a range of a plurality of values characterizing the purchase offer is provided in at least one graphical user interface. If a purchase transaction for the parcel of real property has closed, a specific value of the plurality of values characterizing the purchase offer is provided in at least one graphical user interface.

Abstract: A passive thermal system for use in aerospace vehicles includes a first passive thermal panel having at least one internal resident heat pipe, wherein the first passive thermal panel is further configured to provide an embedded interface between a portion of the resident heat pipe and at least one heat pipe extending from a neighboring passive thermal panel. The embedded interface is facilitated via an internal channel that is adjacent to the internal resident heat pipe. The channel is dimensioned and arranged to receive a portion of a heat pipe extending from a passive thermal panel that will be situated adjacent to the first passive thermal panel. The embedded interface is also facilitated by an arrangement that imparts a compressive force to the non-resident heat pipe that urges it against the resident heat pipe.

Abstract: A powered balancing mobility device that can provide the user the ability to safely navigate expected environments of daily living including the ability to maneuver in confined spaces and to climb curbs, stairs, and other obstacles, and to travel safely and comfortably in vehicles. The mobility device can provide elevated, balanced travel.

Abstract: This disclosure features artificial tympanic membrane graft devices and two-component bilayer graft devices that include a scaffold having a plurality of ribs made of a first material and a plurality of spaces between the ribs filled or made with the first material, a different, second material, a combination of the first and a second materials, or a combination of a second material and one or more other different materials. The bilayer graft devices have two components or layers. One component, e.g., the under-lay graft device, can include a projection, and the second component, e.g., the overlay graft device, can include an opening that corresponds to the projection (or vice versa) so that the opening and the projection can secure the two layers together in a “lock and key” manner. This disclosure also features methods of making, using, and implanting the three-dimensional artificial tympanic membrane and bilayer graft devices.

Abstract: A metathesized natural oil composition comprising (i) a mixture olefins and/or esters, or (ii) a metathesized natural oil, is disclosed. The metathesized natural oil composition has a number average molecular weight in the range from about 100 g/mol to about 150,000 g/mol, a weight average molecular weight in the range from about 1,000 g/mol to about 100,000 g/mol, a z-average molecular weight in the range from about 5,000 g/mol to about 1,000,000 g/mol, and a polydispersity index of about 1 to about 20. The metathesized natural oil composition is metathesized at least once.

Abstract: An apparatus is provided for dynamically controlling airflow behind a carrier aircraft to redirect air flow during an in-flight recovery of an unmanned aerial vehicle (UAV). The apparatus comprises a frame attached to an end portion of an arm member extending from the carrier aircraft. The apparatus comprises a plurality of vanes disposed within the frame. Each vane is controllable between an opened position and a closed position to dynamically modify the airflow behind the carrier aircraft during the in-flight recovery of the UAV. Alternatively, or in addition to, the apparatus comprises a plurality of compressed air jets disposed on the frame, wherein each jet is controllable to provide active airflow to dynamically modify the airflow behind the carrier aircraft during the in-flight recovery of the UAV.

Abstract: Methods and compositions are provided for refining natural oils and for producing high-weight esters, high-weight acids, and/or high-weight derivatives thereof, wherein the compositions are made by cross-metathesizing low-weight unsaturated esters or low-weight unsaturated acids having hydrocarbon chain lengths less than or equal to C24 with an olefin feedstock, thereby forming a metathesized product composition including high-weight esters or high-weight acids having hydrocarbon chain lengths greater than C18, wherein at least a portion of the hydrocarbon chain lengths in the metathesized product are larger than the hydrocarbon chain lengths in the starting feedstock.

Abstract: A cooling system is provided for a 3D integrated circuit (IC) to deliver fluid in x, y, and z dimensions to interior regions of the IC as a means to regulate heat. An IC includes a microfluidic network of channels, at least one sensor and at least one microelectromechanical system (MEMS)-based device that is disposed within the network of channels and that is configured to regulate a flow of fluid within the network of channels. Each sensor monitors a state of the IC. Each MEMS-based device receives control signals based on a state of the IC and regulates a flow of fluid within the network of channels based on control signals that area received on a real-time basis based on changes detected in a state of the IC.

Abstract: A system and associated method for computerized rotational head impulse test (crHIT) to assess the semicircular canals of the human vestibular system clinically in patients with balance disorders. The system utilizes a rotary chair combined with a head mounted VOG system with head tracking sensors. The crHIT protocol uses the same physiologic principles as the known video head impulse test (vHIT). The crHIT utilizes whole-body rotation via the chair to yield a persistent controlled, repeatable, comfortable, reliable stimulus can be delivered while recording eye movements with video-oculogaphy.

Abstract: A viewer device for observing and recording images of materials, such as chemical and biological materials is described. The viewer device includes a housing that provides a chamber for receiving a sample or a sample container that contains a sample of a material (e.g., chemical or biological material). The housing includes a viewing window for observing the sample, a port through which the sample or the sample container can be introduced to or removed from the chamber, and a coupling mechanism configured to removably and replaceably couple the housing to an observational device, such as a camera equipped device.

Abstract: The systems described herein provide a remote keyboard service for a media device on a computing device without having to invoke an application or unlock the computing device. The computing device can receive a message indicating that a text input field on the other device is selected and present a notification to the user prompting the user to invoke the virtual keyboard on the computing device to provide text input to the selected text input field. The computing device can receive user input selecting the notification and present a virtual keyboard for providing text input to the other device. The computing device can receive keyboard input from the user selecting characters and send the characters to the other device. The other device can then user the characters as text input to the selected text input field.

Abstract: A head mounted compact goggle based video oculography system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

Abstract: An apparatus is provided for dynamically controlling airflow behind a carrier aircraft to redirect air flow during an in-flight recovery of an unmanned aerial vehicle (UAV). The apparatus comprises a frame attached to an end portion of an arm member extending from the carrier aircraft. The apparatus comprises a plurality of vanes disposed within the frame. Each vane is controllable between an opened position and a closed position to dynamically modify the airflow behind the carrier aircraft during the in-flight recovery of the UAV. Alternatively, or in addition to, the apparatus comprises a plurality of compressed air jets disposed on the frame, wherein each jet is controllable to provide active airflow to dynamically modify the airflow behind the carrier aircraft during the in-flight recovery of the UAV.

Abstract: A wireless data processing device is described which periodically exits an unpowered state and transmits location data. For example, one embodiment of a wireless data processing device comprises: power circuitry for maintaining the wireless data processing device in a powered or unpowered state, the power circuitry causing the wireless data processing device to enter into an unpowered state responsive to user input; a timer to periodically power up the wireless device or portion thereof in response to reaching a predetermined time; a location services module determining a current location of the wireless data processing device using one or more specified location determination techniques; a transmit thread transmitting the current location of the wireless device over one or more specified communication channels; and the power circuitry powering down the wireless data processing device a second time after the current location has been transmitted.

Abstract: A connected health care system is provided with various devices for tracking and monitoring health statistics and behaviors including oral health, fitness, heart health, bone health, salivary diagnostics, diabetes, and further options that will be explored in the subsequent sections. The connected health care system is comprised of various devices, a data transfer medium (i.e. “smartphone”), and the Cloud, which allows for data transfer between multiple platforms and devices. Some devices comprised in the connected health care system include a toothbrush, a connected surface with sensors, a salivary diagnostic system, a breath analysis system, and further devices that will be explored in the subsequent sections. The connected health care system further provides a user identification system utilizing capacitive coupling of the human body between devices.

Abstract: Body lumen occlusion apparatus and methods are described.

Abstract: This disclosure provides collector plates for an energy storage device, energy storage devices with a collector plate, and methods for manufacturing the same. In one aspect, a collector plate includes a body. One or more apertures extend into the body. The apertures are configured to allow a portion of a free end of a spirally wound current collector of a spirally wound electrode for an energy storage device to extend into the one or more apertures.