Abstract: A satellite frame includes a one-piece integrated body defining a plurality of sides for attaching satellite components thereto. Use of the single integrated satellite body minimizes the amount of fasteners and alignment equipment and processes. Use of the single piece frame also allows for the maximum possible specific stiffness by greatly reducing the number of connections and structural interfaces.

Abstract: A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

Abstract: The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.

Abstract: A method and system is disclosed for estimating the difference between binding free energies of molecules.

Abstract: Exemplary embodiments for use in a communications source network node for identifying a destination port associated with a destination network node to which a selected network link is connected. The embodiments include receiving a communications protocol packet at a destination network node via said selected network link connected to the destination port associated with the destination network node; inspecting the packet for a predetermined identifier; and if the predetermined identifier is present in said packet then outputting an indication that the identifier has been received comprising an identification of the destination port via which the packet was received. The indication is output by at least one of illumination for a pre-set period of a destination switch associated with the destination port, and by an output provided via a user interface of a network interface controller associated with the destination port.

Abstract: Systems and methods for scoring a domain web traffic based on DNS traffic requests received at an authoritative name server to resolve the domain name. A request to resolve the domain name is received at an authoritative name server. A counter, such as a server counter or a hit counter, for the domain name is incremented based on the received request. A score, such as a domain traffic score or a domain rank, is calculated based upon a count of the counter. Calculating the score may also include applying a weighting factor to the counters based on information about a requesting set of resolvers and other domains/websites that may be linking and driving traffic to the domain whose traffic score is being calculated. Examples of relevant set of resolvers information may include location, traffic levels, traffic type and architecture of the set of resolvers.

Abstract: A method of encoding digital content is provided that allows for adaptive joint bitrate allocation that allocates bits for audio and video. The method includes: determining an overall transport stream bitrate, determining a target audio bitrate for each audio stream based on their complexity, determining a portion of the overall transport stream bitrate available for video streams by subtracting the sum of the target audio bitrates from the overall transport stream bitrate, allocating a target video bitrate for each video streams out of the portion of the overall transport stream bitrate available for video streams, encoding audio streams at the target audio bitrates, encoding video streams at the target video bitrates, and combining the audio streams and video streams with a multiplexor into a transport stream.

Abstract: An opioid narcotics used for the treatment of moderate-to-severe pain that primarily exert their analgesic effects through ? receptors. Although, traditional ? agonists can cause undesired side effects, including tolerance, addition of ? antagonists can attenuate said side effects. The present invention includes 4a,9-dihydroxy-7a-(hydroxymethyl)-3-methyl-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one (UMB 425) a 5,14-bridged morphinan-based orvinol precursor, along with analogs of morphine, dihydromorphine, hydromorphone, codeine, dihydrocodeine, hydrocodone and ethylmorphine. Although UMB 425 lacks ?-specific motifs, conformationally sampled pharmacophore models for ? and ? receptors predict it to have efficacy similar to morphine at ? receptors and similar to naltrexone at ? receptors, due to the compound sampling conformations in which the hydroxyl moiety interacts with the receptors similar to orvinols.

Abstract: A gastrointestinal device for implanting within a pylorus, a duodenal bulb, and a duodenum of a patient's gastrointestinal tract includes an expandable structure includes a proximal portion having a plurality of spring arms and a distal portion having a plurality of spring arms, the proximal and distal portions coupled by a rigid central cylinder having a diameter capable of fitting within the pylorus and having a length greater than a width of the pylorus. A membrane is coupled to and covering at least a portion of one of the proximal portion and the distal portion of the expandable structure. An intestinal bypass sleeve is coupled to at least one of the proximal and distal portions of the expandable structure and having a length sufficient to extend at least partially into the duodenum.

Abstract: A display comprising an array of pixels having individually adjustable brightness levels; an array of light sensors fixed relative to the pixel array; and a brightness controller for estimating a glare footprint on the pixel array from light level data provided by the sensor array and for adjusting the relative brightness levels of pixels that fall in the estimated glare footprint.

Abstract: A data intake and query system provides interfaces that enable users to configure source type definitions used by the system. A data intake and query system generally refers to a system for collecting and analyzing data including machine-generated data. Such a system may be configured to consume many different types of machine data generated by any number of different data sources including various servers, network devices, applications, etc. At a high level, a source type definition comprises one or more properties that define how various components of a data intake and query system collect, index, store, search and otherwise interact with particular types of data consumed by the system. The interfaces provided by the system generally comprise one or more interface components for configuring various attributes of a source type definition.

Abstract: Provided are systems and methods for managing storage of machine data. In one embodiment, a method can be provided. The method can include receiving, from one or more data sources, raw machine data; processing the raw machine data to generate processed machine data; storing the processed machine data in a data store; and determining an allocated data size associated with the processed machine data stored in the data store, wherein the allocated data size is the size of the raw machine data corresponding to the processed machine data stored in the data store.

Abstract: Provided are systems and methods for causing display of an index management graphical user interface (GUI). In one embodiment, a method can be provided. The method can include causing display of an index management GUI including one or more user editable fields for specifying one or more index settings; receiving, via the one or more user editable fields of the index management GUI, one or more user specified index settings; generating an index definition corresponding to the one or more user specified index settings; and distributing the index definition to one or more indexers of a data processing system. The one or more indexers are able to manage storage of data in one or more indexes based at least in part on the index definition.

Abstract: Methods of making branched isoparaffin compositions derived from natural oil based linear internal olefins are disclosed. Uses of branched isoparaffins formed by such methods are also disclosed.

Abstract: A network includes vehicle(s) having a battery pack and vehicle telematics unit (VTU), and a server. A server in communication with the VTUs and remote client device(s) is programmed to receive vehicle information from the VTU, including an energy throughput value defined by charging power delivered to the battery pack during an active charging event. The server receives utility information and a load adjustment request from the remote client device, including a power interrupt permission status describing whether interruption of power by a host of the client device is permitted. Charging control signals are transmitted in response to the load adjustment request to enable or postpone the charging event. Energy throughput is recorded over multiple active charging events, which are then combined or aggregated. Output data, e.g., a bill or report describing the aggregated energy throughput values, may be generated by the server. A method and server are also disclosed.

Abstract: A decoration made from a plurality of colored objects arranged in a regular pattern on a colored substrate, individual colored objects discernable at arm's length, with the decoration recognizable at greater distance as corresponding to a digital image. The colored objects may be pushpins, and no colored objects are placed at positions where the substrate color is the desired color. Embodiments also include an apparatus to select a single pushpin from a container of pushpins, and an apparatus to orient a pushpin in preparation for insertion into the substrate.

Abstract: Methods and compositions are provided for refining natural oils and for producing high-weight esters, high-weight acids, and/or high-weight derivatives thereof, wherein the compositions are made by cross-metathesizing low-weight unsaturated esters or low-weight unsaturated acids having hydrocarbon chain lengths less than or equal to C24 with an olefin feedstock, thereby forming a metathesized product composition including high-weight esters or high-weight acids having hydrocarbon chain lengths greater than C18, wherein at least a portion of the hydrocarbon chain lengths in the metathesized product are larger than the hydrocarbon chain lengths in the starting feedstock.

Abstract: An apparatus includes an instruction decoder, first and second source registers and a circuit coupled to the decoder to receive packed data from the source registers and to unpack the packed data responsive to an unpack instruction received by the decoder. A first packed data element and a third packed data element are received from the first source register. A second packed data element and a fourth packed data element are received from the second source register. The circuit copies the packed data elements into a destination register resulting with the second packed data element adjacent to the first packed data element, the third packed data element adjacent to the second packed data element, and the fourth packed data element adjacent to the third packed data element.

Abstract: A kitchen appliance includes a housing that defines a cavity. The housing has a housing rim defining an opening to the cavity. A heating or cooling element is disposed within the housing to heat or cool the cavity. A container has a generally hollow interior and a container rim. A lid is sized and shaped to at least partially cover the opening of the container when placed on the container. The lid has an exterior surface and an opposing interior surface. At least one latching mechanism or handle is operable to seal the contents of the appliance within the appliance.

Abstract: Described herein are methods directed to determining the carrier status or genotype of a subject. Described herein is a method that combines experimental and computational approaches to resolve the structure of genomic loci (i.e., the genotype) whose sequences are highly homologous to other sequences in the genome. In particular, the determination of carrier status and/or copy number of a gene in a subject, wherein the gene has a corresponding highly homologous homolog, e.g., gene or pseudogene, utilizes Next Generation Sequencing. Also described herein is a computer-assisted method for such determinations.