Patents by Inventor Alexander Govyadinov

Alexander Govyadinov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11364498
    Abstract: The present disclosure is drawn to microfluidic devices. In one example, a microfluidic device can include a first covered fluid feed slot in fluid communication with a first microfluidic channel and a second covered fluid feed slot in fluid communication with a second microfluidic channel. The first microfluidic channel can be formed adjacent to the second microfluidic channel but not in fluid communication with the second microfluidic channel. The first covered fluid feed slot can include a first fluid feed hole for filling a fluid into the first covered fluid feed slot. The second covered fluid feed slot can also include a second fluid feed hole for filling a fluid into the second covered fluid feed slot.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: June 21, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Adam Higgins, Pavel Kornilovich
  • Publication number: 20220184610
    Abstract: In example implementations, an apparatus is provided. The apparatus includes a channel, an energy source, and a transfection chamber. The channel includes an indentation to hold a cell. The energy source is to apply a shockwave to the cell in the channel to porate the cell. The transfection chamber is to store a reagent to be inserted into the cell after the cell is porated.
    Type: Application
    Filed: July 25, 2019
    Publication date: June 16, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Viktor Shkolnikov, Diane R. Hammerstad
  • Patent number: 11345162
    Abstract: A fluid recirculation channel for dispensing a plurality of fluid drop weights includes a number of sub-channels. The sub-channels include at least one pump channel, and a plurality of drop generator channels fluidically coupled to the at least one pump channel. The fluid recirculation channel further includes a number of pump generators incorporated into the at least one pump channel, a number of drop generators incorporated into drop generator channels, and a plurality of nozzles defined within the drop generator channels, the nozzles being at least as numerous as the number of drop generators.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: May 31, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Ron Burns, Erik D. Torniainen, Galen P. Cook, David P. Markel, Garrard Hume, Chris Bakker
  • Publication number: 20220163559
    Abstract: The present invention relates to a method for measuring the dielectric properties of a sample with a scanning probe microscope. In particular, the invention relates to highly-localized optical imaging and spectroscopy on a sample surface using an atomic force microscope (AFM) probe mechanically driven at two oscillation frequencies, referred to herein as “active bimodal operation”, and a modulated source of electromagnetic radiation.
    Type: Application
    Filed: April 9, 2020
    Publication date: May 26, 2022
    Inventors: Alexander A. GOVYADINOV, Florian HUTH, Ivan MALOVICHKO, Marcus DIEM
  • Publication number: 20220162645
    Abstract: In example implementations, an apparatus is provided. The apparatus includes a channel, a thermal inkjet (TIJ) resistor, and a transfection chamber. The TIJ resistor is to apply heat to a cell in the channel to porate the cell. The transfection chamber is to store a reagent to be inserted into the cell after the cell is porated.
    Type: Application
    Filed: July 25, 2019
    Publication date: May 26, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Viktor Shkolnikov, Alexander Govyadinov, Diane R. Hammerstad
  • Publication number: 20220161568
    Abstract: An example printing fluid pen comprises a plurality of fluid ports, a pressure regulator in fluid communication with a first fluid port, and a valve in fluid communication with a second fluid port. The first fluid port is to deliver printing fluid to a fluid ejection device, and the second fluid port to direct printing fluid out of the pen. In response to negative pressure, the valve is to open to enable fluids within the pen to exit via the second port.
    Type: Application
    Filed: July 31, 2019
    Publication date: May 26, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Ronald Albert Askeland, Blair A. Butler, Ronald J. Ender, Craig L. Malik, Daniel D. Dowell, Seth Stephen Haddix, Si-lam J. Choy, Alexander Govyadinov
  • Patent number: 11331669
    Abstract: An apparatus may include a first microfluidic valve coupled between a first reservoir and a fluid channel. The first microfluidic valve may include a fluid agitator to break a meniscus formed at an air-fluid interface and release fluid from the first reservoir into the fluid channel in response to an electrical signal. The apparatus may also include a second microfluidic valve coupled between a second reservoir and the fluid channel. Fluid from the first reservoir and fluid from the second reservoir mix in the fluid channel.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: May 17, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Pavel Kornilovich, Alexander Govyadinov, Nick McGuinness
  • Publication number: 20220145331
    Abstract: Examples disclosed herein relate to single cell transfection with interchangeable reagent. The present disclosure relates generally to a device, method, and system for single cell transfection including a transfection chamber on a transfection chip. The example system may include a fluidic channel located on the transfection chip for guiding a cell towards the transfection chamber, the fluidic channel sized to allow no more than a single cell to arrive at the transfection chamber at a time. The example system may also include a reagent receiver located on the transfection chip guiding received reagent towards the transfection chamber and intersecting with the path of the fluidic channel.
    Type: Application
    Filed: June 24, 2019
    Publication date: May 12, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Viktor Shkolnikov, Alexander Govyadinov
  • Publication number: 20220143606
    Abstract: The present disclosure is drawn to microfluidic devices. The microfluidic device includes a substrate, an optically translucent lid, an adhesive securing the substrate to the lid, and an optical barrier material between the substrate and the optically translucent lid.
    Type: Application
    Filed: July 26, 2019
    Publication date: May 12, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Randall Orson Willard, Jeffrey R. Pollard, Alexander Govyadinov, Tod Woodford
  • Publication number: 20220146383
    Abstract: The present disclosure is drawn to a method of labeling and identifying microfluidic samples. The method can include tagging a first microfluidic sample with a first combination of markers to obtain a first labeled sample; tagging a second microfluidic sample with a second combination of markers that is different than the first combination of markers to obtain a second labeled sample; introducing a common variable to the first labeled sample and the second labeled sample. The common variable can generates a first interaction with the first labeled sample that is different than a second interaction or lack of interaction with the second labeled sample. The method can further include based on the first interaction, identifying the first labeled sample by assaying for the first combination of markers.
    Type: Application
    Filed: July 26, 2019
    Publication date: May 12, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Viktor Shkolnikov
  • Publication number: 20220143594
    Abstract: In example implementations, a cell trapping array is provided. The cell trapping array includes a plurality of plates coupled along adjacent edges to form a channel. A plurality of orifices are formed in a first plate of the plurality of plates of the channel. The plurality of orifices is shaped to create a meniscus of a fluid in the channel in the plurality of orifices that is to attract a single cell from cells flowing through the channel in the fluid. The cell trapping array includes a selective ejection system coupled to a second plate located opposite the first plate of the channel. The selective ejection system is to selectively eject the single cell from one of the plurality of orifices.
    Type: Application
    Filed: July 25, 2019
    Publication date: May 12, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Viktor Shkolnikov
  • Patent number: 11325380
    Abstract: An example device includes a first droplet ejector including a first nozzle to eject droplets of a first fluid, and a first target medium positioned relative to the first droplet ejector to receive the droplets of the first fluid from the first droplet ejector. The example device further includes a second droplet ejector in fluid communication with the first target medium to receive a second fluid from the first target medium. The second droplet ejector includes a second nozzle to eject droplets of the second fluid.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: May 10, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Pavel Kornilovich, Alexander Govyadinov, John Lahmann, Paul J. Benning
  • Patent number: 11318466
    Abstract: One example includes a device that may include a heating element and a molecular binding site. The heating element may heat a fluid volume, interfaced with the heating element, in response to a voltage being applied to the heating element, the heat transforming the fluid volume from a liquid state into a vaporized state to generate fluid motion within the fluid volume. The molecular binding site may be disposed proximate to the heating element, in which a portion of the fluid volume expands when the fluid volume transforms from the liquid state into the vaporized state, the vaporized state of the fluid volume generating the fluid motion within a target fluid that is disposed within the molecular binding site.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: May 3, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: David P. Markel, Erik D Torniainen, Alexander Govyadinov, Pavel Kornilovich
  • Publication number: 20220118450
    Abstract: The present disclosure relates to a microfluidic device including a microfluidic substrate and dry reagent-containing particles. The microfluidic substrate includes an ingress microfluidic channel that fluidly feeds an egress microfluidic channel through a microfluidic-retaining region that includes a microfluidic discontinuity feature, a particle-retaining chemical coating, or a combination thereof. The dry reagent-containing particles include a reagent that is releasable from the dry reagent-containing particles when exposed to a release fluid. The dry reagent-containing particles are retained within the microfluidic substrate at the microfluidic discontinuity feature or particle-retaining chemical coating in position to release the reagent into the egress microfluidic channel upon flow of release fluid from the ingress microfluidic channel through the microfluidic-retaining region.
    Type: Application
    Filed: April 30, 2019
    Publication date: April 21, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Viktor Shkolnikov, Alexander Govyadinov
  • Publication number: 20220112453
    Abstract: Examples herein involve cell lysis with a microbead and thermal resistor. An example apparatus includes a microfluidic channel to pass a volume including a microbead and a biologic sample having nucleic acids enclosed within a cellular membrane. A first thermal resistor may be disposed within the microfluidic channel to move the biologic sample through the microfluidic channel and lyse the cellular membranes in the biologic sample to release the nucleic acids. A microfilter disposed within the microfluidic channel may filter the microbead from the biologic sample and permit the nucleic acids to pass through the filter.
    Type: Application
    Filed: April 30, 2019
    Publication date: April 14, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Pavel Kornilovich, Alexander Govyadinov, Jared Johnson
  • Publication number: 20220113255
    Abstract: An example device includes an array of sensor modules. A sensor module includes a body to be positioned in alignment with a planar target, a light source coupled to the body to emit light to the planar target along a source optical path, and a plurality of light sensors coupled to the body. Each light sensor is to sense a different wavelength of light received from the planar target along a sensor optical path. The sensor optical path is different from the source optical path. The bodies of the array of sensor modules are arranged in a planar tiling pattern with respect to a longitudinal axis of the planar target.
    Type: Application
    Filed: April 30, 2019
    Publication date: April 14, 2022
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Brett E. Dahlgren, Brian John Keefe
  • Patent number: 11278889
    Abstract: A sample test device is provided that includes a body having an insertion surface spaced apart from a distal end portion and a fluid manipulating assembly disposed in the distal end portion. A mixing receptacle is defined in the fluid manipulating assembly and provides a volume to mix a test mixture. A plunger is disposed in the body and creates a positive air pressure in the mixing receptacle when inserted into the body. A test die is disposed in the fluid manipulation assembly and a fluid path extends from the mixing receptacle to the test die. Activation of the plunger creates a positive pressure in the mixing receptacle to force the test mixture to flow from the mixing receptacle to the test die.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: March 22, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Jeremy Harlan Donaldson, Stephen Lee Frey, Alexander Govyadinov
  • Patent number: 11279137
    Abstract: An example device includes a first substrate including a first array of droplet ejectors to eject droplets of a first fluid. The example device further includes a first target medium immovably positioned relative to the first substrate to receive droplets of the first fluid from a first subset of droplet ejectors of the first array of droplet ejectors. A second subset of droplet ejectors of the first array of droplet ejectors is positioned to eject droplets of the first fluid to miss the first target medium.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: March 22, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Pavel Kornilovich, Diane R Hammerstad
  • Patent number: 11278894
    Abstract: The present disclosure is drawn to microfluidic devices. In one example, a microfluidic device can include a driver chip and a fluid chamber located over the driver chip. First and second microfluidic loops can have fluid driving ends and fluid outlet ends connected to the fluid chamber. The first and second microfluidic loops can include a portion thereof located outside a boundary of the driver chip. A first fluid actuator can be on the driver chip associated with the fluid driving end of the first microfluidic loop to circulate fluid through the first microfluidic loop. A second fluid actuator can be on the driver chip associated with the fluid driving end of the second microfluidic loop to circulate fluid through the second microfluidic loop.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: March 22, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Adam Higgins, Alexander Govyadinov
  • Patent number: 11278891
    Abstract: Example fluidic channels for microfluidic devices are disclosed. In examples disclosed herein, an example microfluidic device includes a body having a microfluidic network. The microfluidic network includes a main fluid channel to transport a biological fluid from a first cavity of the microfluidic network to a second cavity of the microfluidic network. An auxiliary fluid channel is in fluid communication with to the main fluid channel. The auxiliary fluid channel has a first end and a second end. The first end is in fluid communication with the main fluid channel and the second end is spaced from the main fluid channel. A fluid actuator is positioned in the auxiliary fluid channel to induce fluid flow in the main fluid channel.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: March 22, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Alexander Govyadinov, Erik D. Torniainen, Pavel Kornilovich, David P. Markel