Patents by Inventor Alexander Govyadinov
Alexander Govyadinov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240246084Abstract: Apparatuses may be used for nucleic acid amplification. An example apparatus may include an amplification chamber to contain a biochemical reaction associated with amplification of a biologic sample. The biologic sample may include a nucleic acid. The apparatus may also include a heater thermally coupled to the amplification chamber. The apparatus may also include a thermally conductive substrate in contact with the heater and including a liquid coolant passage to pass a liquid coolant through the thermally conductive substrate.Type: ApplicationFiled: May 10, 2021Publication date: July 25, 2024Applicant: Hewlett-Packard Development Company, L.P.Inventors: Carson Denison, Alexander Govyadinov, Richard W. Seaver, Erik D. Torniainen, Pavel Kornilovich, Anand Samuel Jebakumar
-
Patent number: 12031915Abstract: An example device includes an array of sensor modules. A sensor module includes a body to be positioned in alignment with a planar target, a light source coupled to the body to emit light to the planar target along a source optical path, and a plurality of light sensors coupled to the body. Each light sensor is to sense a different wavelength of light received from the planar target along a sensor optical path. The sensor optical path is different from the source optical path. The bodies of the array of sensor modules are arranged in a planar tiling pattern with respect to a longitudinal axis of the planar target.Type: GrantFiled: April 30, 2019Date of Patent: July 9, 2024Assignee: Hewlett-Packard Development Company, L.P.Inventors: Alexander Govyadinov, Brett E. Dahlgren, Brian John Keefe
-
Patent number: 12025549Abstract: A system includes a microchannel analysis region, a first fluid actuation device, a second fluid actuation device, a sensor, and a controller. The first fluid actuation device is at a first end of the microchannel analysis region. The second fluid actuation device is at a second end of the microchannel analysis region opposite to the first end. The sensor is within the microchannel analysis region between the first fluid actuation device and the second fluid actuation device. The sensor measures an impedance of a fluid within the microchannel analysis region. The controller activates the first fluid actuation device to generate a first pressure wave in the fluid and activates the second fluid actuation device to generate a second pressure wave in the fluid. The first pressure wave and the second pressure wave converge at the sensor.Type: GrantFiled: May 13, 2019Date of Patent: July 2, 2024Assignee: Hewlett-Packard Development Company, L.P.Inventors: Viktor Shkolnikov, Alexander Govyadinov, Diane R. Hammerstad
-
Publication number: 20240207857Abstract: A droplet PCR system is described herein. The droplet PCR system comprises a chamber having a heating surface, a droplet dispenser to dispense PCR-reagent-containing droplets into the chamber, a heater disposed onto the heating surface of the chamber to heat a layer of fluid adjacent the heating surface, and a controller to control the heater to produce a pulsed heat flux.Type: ApplicationFiled: April 29, 2021Publication date: June 27, 2024Applicant: Hewlett-Packard Development Company, L.P.Inventors: Viktor Shkolnikov, Alexander Govyadinov
-
Publication number: 20240181449Abstract: A microfluidic device includes a first channel, second channels, and a transition channel splitting the first channel into the second channels. The transition has a first end fluidically connected to the first channel and a second end fluidically connected to the second channels. The transition channel expands in width from a width of the first channel at the first end to no less than a sum of widths of the second channels at the second end so as to promote fluid flow from the first channel to the second channels.Type: ApplicationFiled: April 6, 2021Publication date: June 6, 2024Applicant: Hewlett-Packard Development Company, L.P.Inventors: Carson DENISON, Pavel KORNILOVICH, Richard W. SEAVER, Anand Samuel JEBAKUMAR, Erik D. TORNIANEN, Alexander GOVYADINOV
-
Publication number: 20240165617Abstract: A microfluidic device includes a first channel having a first width and a second channel having a second width greater than the first width. The microfluidic device includes a transition channel having a first end fluidically connected to the first channel and a second end fluidically connected to the second channel. The transition channel expands in width from the first width to the second width so as to promote fluid flow from the first channel to the second channel.Type: ApplicationFiled: April 6, 2021Publication date: May 23, 2024Applicant: Hewlett-Packard Development Company, L.P.Inventors: Erik D. TORNIANEN, Carson DENISON, Richard W. SEAVER, Anand Samuel JEBAKUMAR, Pavel KORNILOVICH, Alexander GOVYADINOV
-
Patent number: 11988594Abstract: An example system includes an input channel having a first end and a second end to receive particles through the first end, a sensor to categorize particles in the input channel into one of at least two categories, and at least two output channels. Each output channel is coupled to the second end of the input channel to receive particles from the input channel, and each output channel is associated with at least one category of the at least two categories. Each output channel has a corresponding pump operable, based on the categorization of a detected particle in a category associated with a different output channel, to selectively slow, stop, or reverse a flow of particles into the output channel from the input channel.Type: GrantFiled: May 12, 2023Date of Patent: May 21, 2024Assignee: Hewlett-Packard Development Company, L.P.Inventors: Alexander Govyadinov, Pavel Kornilovich
-
Patent number: 11970011Abstract: A fluid-ejection element of a fluid-ejection device includes a chamber layer having a pair of chambers fluidically disconnected from one another within the chamber layer. The fluid-ejection element includes a tophat layer over the chamber layer and fluidically connecting the chambers to define a fluid recirculation path between the chambers. The fluid-ejection element includes a nozzle common to both the chambers.Type: GrantFiled: March 5, 2020Date of Patent: April 30, 2024Assignee: Hewlett-Packard Development Company, L.P.Inventors: Jacob Lum, Alexander Govyadinov
-
Publication number: 20240123446Abstract: A microfluidic system may comprise a dispense head with multiple dispensers, each dispensing a different cell type, such as single pairs of individual target cells and individual sensor cells. Interaction between the cells may be observed based on, for example, fluorescence. Individual target cells may then be selected, based on observations, for use or for further investigation. As an example, target cells may be B-cells, and enhanced selection of B-cells aids more direct antibody discovery.Type: ApplicationFiled: May 26, 2023Publication date: April 18, 2024Applicant: Hewlett-Packard Development Company, L.P.Inventors: Alexander Govyadinov, Viktor Shkolnikov
-
Patent number: 11938727Abstract: Fluid is continuously recirculated through a thermal fluid-ejection printhead. Prior to firing a thermal resistor of the printhead to thermally eject a drop of the fluid through a nozzle of the printhead, the fluid is recirculated on-demand through a chamber of the printhead between the nozzle and the thermal resistor. The thermal resistor is fired to thermally eject the drop of the fluid through the nozzle. The fluid has a concentration of solids greater than 12% by volume.Type: GrantFiled: February 14, 2020Date of Patent: March 26, 2024Assignee: Hewlett-Packard Development Company, L.P.Inventors: Alexander Govyadinov, Alex Trubnikov, Ronald Albert Askeland
-
Publication number: 20240082839Abstract: A microfluidic device includes a chamber having sidewalls, a floor, a ceiling, and an inlet. The microfluidic device includes pillars extending from the floor to the ceiling of the chamber. Each pillar has an orientation relative to the inlet defined by a leading surface and a trailing corner opposite the leading corner. The trailing corner has an angle less than a threshold angle that is based on a fluidic contact angle. The orientations of the pillars relative to the inlet promote fluid flow from the inlet throughout the chamber without trapping gas at the sidewalls of the chamber.Type: ApplicationFiled: January 22, 2021Publication date: March 14, 2024Applicant: Hewlett-Packard Development Company, L.P.Inventors: Carson DENISON, Erik D. TORNIAINEN, Richard W. SEAVER, Pavel KORNILOVICH, Alexander GOVYADINOV, Anand Samuel JEBAKUMAR
-
Patent number: 11899041Abstract: The present invention relates to a method for referencing a near-field measurement, e.g. in a scanning probe microscope.Type: GrantFiled: July 16, 2021Date of Patent: February 13, 2024Assignee: ATTOCUBE SYSTEMS AGInventors: Ivan Malovichko, Florian Huth, Alexander A. Govyadinov, Marcus Diem
-
Publication number: 20240033728Abstract: A microfluidic processing system can include a reagent delivery network including an inlet microfluidic channel fluidly coupled to an outlet microfluidic channel via a microfluidic cross-channel. The microfluidic cross-channel can include a constriction region and a reagent storage chamber. The microfluidic processing system can also include a resistor positioned along the inlet microfluidic channel at a location to redirect fluid through the constriction region and into a reagent storage chamber, and process microfluidics fluidly coupled downstream from the outlet microfluidic channel.Type: ApplicationFiled: July 29, 2022Publication date: February 1, 2024Applicant: Hewlett-Packard Development Company, L. P.Inventors: Viktor Shkolnikov, Alexander Govyadinov
-
Publication number: 20240033729Abstract: A reagent delivery network can include an inlet microfluidic channel, a microfluidic cross-channel branching off from the inlet microfluidic channel, a resistor positioned along the inlet microfluidic channel at a location to redirect fluid from the inlet microfluidic channel into the microfluidic cross-channel, and an outlet microfluidic channel having a side-wall opening connected to the microfluidic cross-channel. The outlet microfluidic channel can receive fluid from the microfluidic cross-channel. The microfluidic cross-channel can include a constriction region and a reagent storage chamber having reagent therein.Type: ApplicationFiled: July 29, 2022Publication date: February 1, 2024Applicant: Hewlett-Packard Development Company, L.P.Inventors: Alexander Govyadinov, Viktor Shkolnikov
-
Patent number: 11879844Abstract: An example device includes an array of sensor modules. A sensor module includes a body to be positioned in alignment with a planar target, a light source coupled to the body to emit light to the planar target along a source optical path, and a plurality of light sensors coupled to the body. Each light sensor is to sense a different wavelength of light received from the planar target along a sensor optical path. The sensor optical path is different from the source optical path. The bodies of the array of sensor modules are arranged in a planar tiling pattern with respect to a longitudinal axis of the planar target.Type: GrantFiled: April 30, 2019Date of Patent: January 23, 2024Assignee: Hewlett-Packard Development Company, L.P.Inventors: Alexander Govyadinov, Brett E. Dahlgren, Brian John Keefe
-
Publication number: 20230415151Abstract: An example self-priming microfluidic structure can include a microfluidic channel including a floor and a ceiling. A channel height is defined as a distance between the floor and the ceiling. A channel height step can be in the floor, or ceiling, or both. The channel height downstream of the channel height step can be greater than the channel height upstream of the channel height step. An interior pillar can be positioned in the microfluidic channel extending from the floor to the ceiling. The interior pillar can include a widening portion at an upstream end of the interior pillar and a tapering portion at a downstream end of the interior pillar. The interior pillar can overlap the channel height step so that the interior pillar is partially upstream of the channel height step and partially downstream of the channel height step.Type: ApplicationFiled: June 24, 2022Publication date: December 28, 2023Applicant: Hewlett-Packard Development Company, L.P.Inventors: Peiyun Wang, Pavel KORNILOVICH, Alexander GOVYADINOV, Noorashekin Binte JAMIL, Sarita JAIRAM, Jinghua ZHAO
-
Publication number: 20230381723Abstract: An example microfluidic mixer can include an inlet microfluidic channel portion and a fluid splitting channel portion including an overpass microfluidic channel to receive fluid from a first side of the inlet microfluidic channel portion and an underpass microfluidic channel to receive fluid from a second side of the inlet microfluidic channel portion, where the underpass microfluidic channel extends under the overpass microfluidic channel such that the channels overlap at their respective downstream ends. A fluid recombining channel portion is downstream of the fluid splitting portion and includes an angled recombining surface having an acute angle with respect to a direction of fluid flow, where the angled recombining surface is between the downstream ends of the overpass and underpass microfluidic channels. An outlet microfluidic channel portion is fluidly connected downstream from the fluid recombining channel portion.Type: ApplicationFiled: May 27, 2022Publication date: November 30, 2023Applicant: Hewlett-Packard Development Company, L.P.Inventors: Carson Denison, Richard W. SEAVER, Erik D. TORNIAINEN, Pavel KORNILOVICH, Alexander GOVYADINOV, Anand Samuel JEBAKUMAR, Oumnia EL FAJRI
-
Publication number: 20230381779Abstract: A method comprising receiving, at a microfluidic channel, a biologic sample including a cell and providing a magnetic field within the microfluidic channel using a first magnet, wherein the magnetic field attracts a first plurality of magnetic particles disposed within the microfluidic channel. The method further includes activating a first resistor disposed within the microfluidic channel to agitate a volume of fluid within the microfluidic channel, and in response, moving the first plurality of magnetic particles through the microfluidic channel to lyse the cell and to release cellular material from the cell.Type: ApplicationFiled: October 20, 2020Publication date: November 30, 2023Applicant: Hewlett-Packard Development Company, L.P.Inventors: Alexander Govyadinov, Viktor Shkolnikov
-
Publication number: 20230372938Abstract: In one example in accordance with the present disclosure, a fluid analysis system is described. The fluid analysis system includes an inlet channel to an analysis chamber. The analysis chamber is to receive a fluid sample to be analyzed. The fluid analysis system also includes a fluid branch having a fluidic junction along the inlet channel and a gas chamber to house a volume of trapped gas, the gas chamber being in fluid communication with the fluid branch. The fluid analysis system also includes a sealing fluid delivery system to fill the fluid branch with a sealing fluid and a heater adjacent the gas chamber to heat the gas chamber such that the trapped gas expands to push the sealing fluid into the inlet channel to seal the analysis chamber.Type: ApplicationFiled: September 14, 2021Publication date: November 23, 2023Applicant: Hewlett-Packard Development Company, L.P.Inventors: Pavel Kornilovich, Alexander Govyadinov
-
Patent number: 11815430Abstract: A nucleic acid detection device includes a microfluidic opening and a sensor stack. The sensor stack includes an electrochemical electrode and a photodetector. The electrochemical electrode is formed of a conductive material that is transparent to a fluorescent emission, the electrochemical electrode including a first side and an opposite second side, wherein the first side is exposed to the microfluidic opening. The photodetector is positioned relative to the second side of the electrochemical electrode to optically receive the fluorescent emission when passed through the electrochemical electrode.Type: GrantFiled: February 22, 2019Date of Patent: November 14, 2023Assignee: Hewlett-Packard Development Company, L.P.Inventors: Alexander Govyadinov, Brett E. Dahlgren