Abstract: An optical operating fluid detector for optical detection of operating fluid for a hand-guided garden, forestry and/or construction machining appliance includes a light source, an operating fluid line and a light receiver. The light source is designed for radiation of rays of light. The operating fluid line is designed for optical interaction of rays of light from the light source with operating fluid in line for the optical detection of operating fluid. The light receiver is designed for differing reception of rays of light from the line in dependence on the presence or the absence of operating fluid in the line. The operating fluid detector has an optical deflecting device. The deflecting device is designed for deflection of rays of light from the light source to the operating fluid line and/or for deflection of rays of light from the line to the light receiver.

Abstract: The present invention relates to antibodies which bind to antigens on target cells and which target effector moieties to said cells, and to methods of using the same.

Abstract: The invention relates to a co-filament comprising a first filament and a second filament, wherein the first filament consists of an inorganic substance, wherein the first filament has a glass transition temperature of greater than or equal to 400° C., wherein the second filament consists of a metallic material, the second filament contacting the first filament. Furthermore, the invention relates to a roving, a yarn and a semi-finished product comprising this co-filament, a use of this co-filament and a method for producing this co-filament.

Abstract: The present invention relates to a set of antibodies which bind to antigens on target cells and which target radionuclides to said cells, and to methods of using the same. The antibodies each comprising a Fab binding to the target antigen fused at the C-terminus of the VH to the N-terminus of the Fc and a VH or VL binding to a radiolabelled compound. The VH or VL are fused at the C-terminus to the N-terminus of the Fc. VH and VL form an antigen binding site when the antibody binds via the scFv to the target antigen.

Abstract: A hand-portable garden, forestry and/or construction processing device has a cutting tool, an electric drive motor, a motor operating element, and a control device. The cutting tool is designed for cutting through work. The drive motor is designed for driving the cutting tool. The motor operating element is user-adjustable over an adjustment range from a minimum setting to a maximum setting. The control device is designed for controlling a target speed of the drive motor in accordance with a setting of the motor operating element in at least one first operating mode and one second operating mode. In the first operating mode, the target speed increases over at least one segment from a minimum of 0.5 times the adjustment range as the setting increases, wherein the increase changes over the segment by a maximum of 60%. In the second operating mode, the target speed is a minimum of 0.9 times a maximum target speed of the second operating mode as the setting increases from a maximum of 50% of the adjustment range.

Abstract: A soldering aid for connecting a cable to a printed circuit board includes an electrically insulating body having a first, second and third recesses, and an electrically conductive contact structure coupled thereto. The contact structure is partially embedded in the body to be connected to a cable core therein, and partially protrudes from the body to be connected the printed circuit board. The first recess is conically tapered to receive an end portion of the cable and has first and second sections for non-stripped and stripped portions of the cable end portion, respectively. An end of the second recess adjoins the second section of the first recess to enable optical verification of formation of a connection between the cable core and the contact structure. The third recess is configured to receive and transfer solder to the second section of the first recess to thereby form the connection.

Abstract: The present application relates to antibodies which bind specifically to chelated radionuclides, including bispecific antibodies. It further relates to the use of such bispecific antibodies in applications such as radioimmunoimaging and radioimmunotherapy. It additionally relates to clearing agents and compositions useful in such methods. The chelated radionuclides may be a DOTAM-lead (Pb) chelate.

Abstract: The present invention relates to antibodies which bind to antigens on target cells and which target radionuclides to said cells, and to methods of using the same.

Abstract: Herein is reported an antibody that specifically hinds to human CD 19, wherein the antibody comprises (a) HVR-H1 comprising the amino acid sequence of SEQ ID NO: 03, (b) HVR-H2 comprising the amino acid sequence of SEQ ID NO: 11, (c) HVR-H3 comprising the amino acid sequence of SEQ ID NO: 05, (d) HVR-L1 comprising the amino acid sequence of SEQ ID NO: 20 or 28, (e) HVR-L2 comprising the amino acid sequence of SEQ ID NO: 07, and (f) HVR-L3 comprising the amino acid sequence of SEQ ID NO: 08, as well as methods of using the same.

Abstract: Herein is reported an antibody binding to rabbit CD19 comprising (a) a HVR-H1 comprising the amino acid sequence of SEQ ID NO: 32 or 33 or 34, (b) a HVR-H2 comprising the amino acid sequence of SEQ ID NO: 35 or 36, (c) a HVR-H3 comprising the amino acid sequence of SEQ ID NO: 37, (d) a HVR-L1 comprising the amino acid sequence of SEQ ID NO: 38, (e) a HVR-L2 comprising the amino acid sequence of SEQ ID NO: 39, and (f) a HVR-L3 comprising the amino acid sequence of SEQ ID NO: 40, as well as methods of using the same, especially in the identification and selection of antibody producing rabbit B-cells.

Abstract: A multijunction solar cell and its method of fabrication, including an upper and a lower solar subcell each having an emitter layer and a base layer forming a photoelectric junction; a near infrared (NIR) wideband reflector layer disposed below the upper subcell and above the lower subcell for reflecting light in the spectral range of 900 to 1050 nm which represents unused and undesired solar energy and thereby reducing the overall solar energy absorptance in the solar cell and providing thermodynamic radiative cooling of the solar cell when deployed in space outside the atmosphere.

Abstract: Herein is reported an antibody that specifically binds to human CD 19, wherein the antibody comprises (a) HVR-H1 comprising the amino acid sequence of SEQ ID NO: 03, (b) HVR-H2 comprising the amino acid sequence of SEQ ID NO: 11, (c) HVR-H3 comprising the amino acid sequence of SEQ ID NO: 05, (d) HVR-L1 comprising the amino acid sequence of SEQ ID NO: 20 or 28, (e) HVR-L2 comprising the amino acid sequence of SEQ ID NO: 07, and (f) HVR-L3 comprising the amino acid sequence of SEQ ID NO: 08, as well as methods of using the same.

Abstract: A multijunction solar cell and its method of fabrication, including an upper and a lower solar subcell each having an emitter layer and a base layer forming a photoelectric junction; a near infrared (NIR) wideband reflector layer disposed below the upper subcell and above the lower subcell for reflecting light in the spectral range of 900 to 1050 nm which represents unused and undesired solar energy and thereby reducing the overall solar energy absorptance in the solar cell and providing thermodynamic radiative cooling of the solar cell when deployed in space outside the atmosphere.

Abstract: The present application relates to antibodies which bind specifically to chelated radionuclides, including bispecific antibodies, It further relates to the use of such bispecific antibodies in applications such as radioimmunoimaging and radioimmunotherapy. It additionally relates to clearing agents and useful in such methods.

Abstract: A soldering aid for connecting a cable to a printed circuit board includes an electrically insulating body having a first, second and third recesses, and an electrically conductive contact structure coupled thereto. The contact structure is partially embedded in the body to be connected to a cable core therein, and partially protrudes from the body to be connected the printed circuit board. The first recess is conically tapered to receive an end portion of the cable and has first and second sections for non-stripped and stripped portions of the cable end portion, respectively. An end of the second recess adjoins the second section of the first recess to enable optical verification of formation of a connection between the cable core and the contact structure. The third recess is configured to receive and transfer solder to the second section of the first recess to thereby form the connection.

Abstract: Herein is reported a method for providing cells that express a fusion protein from a marker protein and a cell-endogenous target protein, consisting of the steps a) transfecting the cells i) with a Cas9-encoding plasmid additionally containing a nucleic acid which is resistant to a first selection agent, ii) with a circular donor plasmid containing a first nucleic acid which confers resistance to a second selection reagent, and a second nucleic acid which encodes the marker protein and which is flanked 3? and 5? by nucleic acids homologous to the integration site in the cell, iii) a suitable synthetic crRNA, and iv) a suitable synthetic tracrRNA, b) cultivating the cells in the presence of the first and the second selection reagent, and c) selecting cells which under the conditions of step b) carry out cell division, and thereby providing/producing cells that express a fusion protein of a marker protein and a cell-endogenous target protein.

Abstract: A multijunction solar cell and its method of fabrication, including an upper and a lower solar subcell each having an emitter layer and a base layer forming a photoelectric junction; a near infrared (NIR) wideband reflector layer disposed below the upper subcell and above the lower subcell for reflecting light in the spectral range of 900 to 1050 nm which represents unused and undesired solar energy and thereby reducing the overall solar energy absorptance in the solar cell and providing thermodynamic radiative cooling of the solar cell when deployed in space outside the atmosphere.

Abstract: The invention relates to novel bispecific antibodies consisting of two fusion polypeptides comprising two antigen binding domains capable of specific binding to a first target and one antigen binding domain capable of specific binding to a second target, and to methods of producing these molecules and to methods of using the same.

Abstract: A hand-portable garden, forestry and/or construction processing device has a cutting tool, an electric drive motor, a motor operating element, and a control device. The cutting tool is designed for cutting through work. The drive motor is designed for driving the cutting tool. The motor operating element is user-adjustable over an adjustment range from a minimum setting to a maximum setting. The control device is designed for controlling a target speed of the drive motor in accordance with a setting of the motor operating element in at least one first operating mode and one second operating mode. In the first operating mode, the target speed increases over at least one segment from a minimum of 0.5 times the adjustment range as the setting increases, wherein the increase changes over the segment by a maximum of 60%. In the second operating mode, the target speed is a minimum of 0.9 times a maximum target speed of the second operating mode as the setting increases from a maximum of 50% of the adjustment range.

Abstract: A hand-guided gardening, forestry and/or construction processing device includes a processing tool, an electric motor drive system, wherein the electric motor drive system is designed to drive the processing tool, a user-adjustable operating element, and a control device. The control device is designed to control a target slope rate of a rotational speed of the electric motor drive system in dependence on a position of the operating element according to at least one allocation in such a way that maximum target slope rates of the rotational speed differ for different positions.