Abstract: A method is provided for operating a hand-guided processing device that has a rotating and/or circulating cutting tool, an electric motor drive system wherein the electric motor drive system is configured for generating a torque for driving the cutting tool, and a user-operable control element. The method automatically monitors whether a blocking criterion is fulfilled, wherein the blocking criterion is characteristic of a blocking of the cutting tool, and if the blocking criterion is fulfilled and the control element operated, automatically lowers the torque generated by the electric motor drive system, and temporally thereafter, automatically increases the torque generated by the electric motor drive system.

Abstract: An optical operating fluid detector for optical detection of operating fluid for a hand-guided garden, forestry and/or construction machining appliance includes a light source, an operating fluid line and a light receiver. The light source is designed for radiation of rays of light. The operating fluid line is designed for optical interaction of rays of light from the light source with operating fluid in line for the optical detection of operating fluid. The light receiver is designed for differing reception of rays of light from the line in dependence on the presence or the absence of operating fluid in the line. The operating fluid detector has an optical deflecting device. The deflecting device is designed for deflection of rays of light from the light source to the operating fluid line and/or for deflection of rays of light from the line to the light receiver.

Abstract: A bone screw system includes a bone screw having a tulip that forms a seat for a longitudinal support for surgical connection of adjacent bone screws. The tulip has a tulip thread into which a clamping screw is screwed. The clamping screw has a clamping screw thread for locking the longitudinal support by clamping within the seat. The clamping screw thread is provided on the run-in side with a thread chamfer. The thread chamfer is introduced to the clamping screw thread while chamfering a thread elevation in the radial direction.

Abstract: A multijunction solar cell and its method of fabrication, including an upper and a lower solar subcell each having an emitter layer and a base layer forming a photoelectric junction; a near infrared (NIR) wideband reflector layer disposed below the upper subcell and above the lower subcell for reflecting light in the spectral range of 900 to 1050 nm which represents unused and undesired solar energy and thereby reducing the overall solar energy absorptance in the solar cell and providing thermodynamic radiative cooling of the solar cell when deployed in space outside the atmosphere.

Abstract: A bone screw system includes a bone screw having a tulip that forms a seat for a longitudinal support for surgical connection of adjacent bone screws. The tulip has a tulip thread into which a clamping screw is screwed. The clamping screw has a clamping screw thread for locking the longitudinal support by clamping within the seat. The clamping screw thread is provided on the run-in side with a thread chamfer. The thread chamfer is introduced to the clamping screw thread while chamfering a thread elevation in the radial direction.

Abstract: Herein is reported a conjugate comprising an antigen and an antibody that specifically binds to the antigen wherein a covalent bond is formed between the antigen and an amino acid residue in the CDR2 of the antibody, an antibody comprising a cysteine residue at amino acid position 53 (according to Kabat) in the heavy chain CDR2 and uses thereof.

Abstract: Herein is reported a conjugate comprising an antigen and an antibody that specifically binds to the antigen wherein a covalent bond is formed between the antigen and an amino acid residue in the CDR2 of the antibody, an antibody comprising a cysteine residue at amino acid position 53 (according to Kabat) in the heavy chain CDR2 and uses thereof.

Abstract: The present disclosure relates to a hydraulic component with a valve unit for a hydraulic system, and a hydraulic system having such a hydraulic component. The valve unit of the hydraulic component has a valve block and a valve piston. The valve piston is moveably along a first bore supported in the valve block. Further, the valve unit is admittable with pressurized hydraulic fluid and is configured such that the valve piston can be moved between a closed position and an open position. The hydraulic component according to the disclosure is particularly characterized in that the first bore is configured as a through-hole through the entire valve block and the hydraulic component has a collecting unit. The collecting unit at least partially surrounds the two end openings of the first bore and is configured collect and drain hydraulic fluid leaking out of the two end openings of the bore.

Abstract: The present disclosure relates to a hydraulic component with a valve unit for a hydraulic system, and a hydraulic system having such a hydraulic component. The valve unit of the hydraulic component has a valve block and a valve piston. The valve piston is moveably along a first bore supported in the valve block. Further, the valve unit is admittable with pressurized hydraulic fluid and is configured such that the valve piston can be moved between a closed position and an open position. The hydraulic component according to the disclosure is particularly characterized in that the first bore is configured as a through-hole through the entire valve block and the hydraulic component has a collecting unit. The collecting unit at least partially surrounds the two end openings of the first bore and is configured collect and drain hydraulic fluid leaking out of the two end openings of the bore.

Abstract: A cable includes a lead having at least one wire, and a connector having at least one contact and a liquid-tight dielectric housing. The at least one contact is electrically connected to the at least one wire such that an electric current is conductible from the at least one wire into the at least one contact. A temperature-sensitive measuring resistor is contained in the housing and is electrically connected to the at least one wire such that at least a portion of the electrical current that is conductible into the at least one contact flows through the measuring resistor. A metallic element is disposed on the housing and thermally connected to the measuring resistor.

Abstract: Herein is reported an antibody that specifically binds to human CD 19, wherein the antibody comprises (a) HVR-H1 comprising the amino acid sequence of SEQ ID NO: 03, (b) HVR-H2 comprising the amino acid sequence of SEQ ID NO: 11, (c) HVR-H3 comprising the amino acid sequence of SEQ ID NO: 05, (d) HVR-L1 comprising the amino acid sequence of SEQ ID NO: 20 or 28, (e) HVR-L2 comprising the amino acid sequence of SEQ ID NO: 07, and (f) HVR-L3 comprising the amino acid sequence of SEQ ID NO: 08, as well as methods of using the same.

Abstract: A multijunction solar cell and its method of fabrication, including an upper and a lower solar subcell each having an emitter layer and a base layer forming a photoelectric junction; a near infrared (NIR) wideband reflector layer disposed below the upper subcell and above the lower subcell for reflecting light in the spectral range of 900 to 1050 nm which represents unused and undesired solar energy and thereby reducing the overall solar energy absorptance in the solar cell and providing thermodynamic radiative cooling of the solar cell when deployed in space outside the atmosphere.

Abstract: A four junction solar cell having an upper first solar subcell composed of a semiconductor material having a first band gap; a second solar subcell adjacent to said first solar subcell and composed of a semiconductor material having a second band gap smaller than the first band gap and being lattice matched with the upper first solar subcell; a third solar subcell adjacent to said second solar subcell and composed of a semiconductor material having a third band gap smaller than the second band gap and being lattice matched with the second solar subcell; and a fourth solar subcell adjacent to and lattice mismatched from said third solar subcell and composed of a semiconductor material having a fourth band gap smaller than the third band gap; wherein the fourth subcell has a direct bandgap of greater than 0.75 eV, and the average band gap of the solar cell is equal to or greater than 1.35 eV.

Abstract: A cable includes a lead having at least one wire, and a connector having at least one contact and a liquid-tight dielectric housing. The at least one contact is electrically connected to the at least one wire such that an electric current is conductible from the at least one wire into the at least one contact. A temperature-sensitive measuring resistor is contained in the housing and is electrically connected to the at least one wire such that at least a portion of the electrical current that is conductible into the at least one contact flows through the measuring resistor. A metallic element is disposed on the housing and thermally connected to the measuring resistor.

Abstract: The present invention relates to bispecific antibodies, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.

Abstract: The present invention relates to complexes of a) bi-specific antibodies and antibody fragments against a target protein and b) a digoxigenin conjugated to a therapeutic or diagnostic agent, methods for their production, their use as a delivery platform for therapeutic or diagnostic agents, pharmaceutical compositions containing said antibodies, and uses thereof.