Patents by Inventor Alexander Klein

Alexander Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240132590
    Abstract: The present invention generally relates to antibodies that bind to CD3 and CD19, e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Application
    Filed: August 8, 2023
    Publication date: April 25, 2024
    Inventors: Anne FREIMOSER-GRUNDSCHOBER, Maria Valeria GONZALEZ NICOLINI, Ralf HOSSE, Alexander KNAUPP, Ekkehard MOESSNER, Wolfgang RICHTER, Halina TROCHANOWSKA, Pablo UMAÑA, Christian KLEIN, Inja WALDHAUER
  • Publication number: 20240129944
    Abstract: For example, a wireless communication device may be configured to determine an expected interference-based value corresponding to an Uplink (UL) transmission from a wireless communication station (STA) in a Trigger-Based (TB) Multi-User (MU) UL transmission to be communicated from a plurality of STAs to the wireless communication device; to determine one or more transmit (Tx) configuration parameters for the STA based on the expected interference-based value corresponding to the UL transmission from the STA; and to transmit a trigger frame to trigger the TB MU UL transmission, the trigger frame including the one or more Tx configuration parameters to configure the UL transmission from the STA.
    Type: Application
    Filed: December 28, 2023
    Publication date: April 18, 2024
    Applicant: INTEL CORPORATION
    Inventors: Alexander W. Min, Arik Klein, Rath Vannithamby, Ziv Avital
  • Publication number: 20240117049
    Abstract: The invention relates to novel bispecific antigen binding molecules, comprising at least two antigen binding domains capable of specific binding to OX40 and a particular antigen binding domain capable of specific binding to Fibroblast Activation Protein (FAP), and to methods of producing these molecules and to methods of using the same.
    Type: Application
    Filed: August 29, 2023
    Publication date: April 11, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Maria AMANN, Juergen Peter BACHL, Alexander BUJOTZEK, Carina CANTRILL, Harald DUERR, Janine FAIGLE, Sabine IMHOF-JUNG, Christian KLEIN, Thomas KRAFT, Estelle MARRER-BERGER, Ekkehard MOESSNER, Laurene POUSSE, Petra RUEGER, Johannes SAM, Roland STAACK, Dietrich TUERCK, Pablo UMANA, Joerg ZIELONKA
  • Publication number: 20240082437
    Abstract: The present invention relates to antibodies which bind to antigens on target cells and which target effector moieties to said cells, and to methods of using the same.
    Type: Application
    Filed: January 10, 2022
    Publication date: March 14, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Christian KLEIN, Alexander HAAS, Sabine IMHOF-JUNG, Sofia FROST
  • Patent number: 11923629
    Abstract: A device may include a frame, a first leg extending from the frame, and a second leg extending from the frame, wherein each of the first leg and the second leg is curved in a respective direction, the respective directions being different.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: March 5, 2024
    Assignee: MELLANOX TECHNOLOGIES LTD.
    Inventors: Tamir Lederman, Aziz Mazbar, Tomer Klein, Alexander Shusterman, Andrey Ger
  • Publication number: 20240067749
    Abstract: The present invention generally relates to antibodies that bind to GPRC5D, including bispecific antigen binding molecules e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Application
    Filed: April 28, 2023
    Publication date: February 29, 2024
    Inventors: GEORG FERTIG, CHRISTIAN KLEIN, STEFAN LORENZ, WEI XU, MARIE-LUISE BERNASCONI, ALEXANDER BUJOTZEK
  • Patent number: 11916003
    Abstract: Embodiments disclosed herein include electronic packages. In an embodiment, the electronic package comprises a first substrate; a second substrate; and an array of interconnects electrically coupling the first substrate to the second substrate. In an embodiment, the array of interconnects comprises first interconnects, wherein the first interconnects have a first volume and a first material composition, and second interconnects, wherein the second interconnects have a second volume and a second material composition, and wherein the first volume is different than the second volume and/or the first material composition is different than the second material composition.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: February 27, 2024
    Assignee: Intel Corporation
    Inventors: Xiao Lu, Jiongxin Lu, Christopher Combs, Alexander Huettis, John Harper, Jieping Zhang, Nachiket R. Raravikar, Pramod Malatkar, Steven A. Klein, Carl Deppisch, Mohit Sood
  • Publication number: 20240003564
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for adjusting an indoor humidity at a property. One of the methods includes determining an estimated outdoor temperature in an area around a property; determining, using the estimated outdoor temperature, a target indoor humidity for the property; accessing data about the property; predicting, using the data about the property, whether an indoor humidity of the property will likely change within a threshold time period; determining, using the target indoor humidity and the prediction whether the indoor humidity of the property will likely change within the threshold time period, whether to adjust the indoor humidity of the property; and in response to determining to adjust the indoor humidity of the property, controlling, using the target indoor humidity, humidity equipment at the property to cause an indoor humidity at the property to move toward the target indoor humidity.
    Type: Application
    Filed: June 21, 2023
    Publication date: January 4, 2024
    Inventors: Jackson Alexander Klein, Robert Nathan Picardi
  • Publication number: 20230303795
    Abstract: The present invention relates to a reaction mixture for manufacturing an inorganic-filler based closed-cell rigid polyurethane or polyisocyanurate (PU or PIR) containing foam having a calorific value below 6 MJ/kg, preferably below 4.5 MJ/kg, more preferably below 3 MJ/kg, measured according to EN ISO 1716, the reaction mixture comprising: At least one polyisocyanate-containing compound; At least one isocyanate-reactive compound; An inorganic filler composition; At least one physical blowing agent; characterised in that said inorganic filler composition has bulk density higher than 2 g/cm3, preferably higher than 2.1 g/cm3, more preferably higher than 2.2 g/cm3, even more preferably higher than 2.4 g/cm3.
    Type: Application
    Filed: July 22, 2021
    Publication date: September 28, 2023
    Inventors: Thomas Julien JONCHERAY, Jeremy Frederic Sylvain BRASSINNE, Gilles Jean GEUMEZ, Nima ESMAEILI, Xiaodong GUO, Maarten MOESEN, Nadja Kathrin RICHTER, Mark Joseph BRENNAN, Rene Alexander KLEIN
  • Publication number: 20230288088
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer-storage media, for monitoring and operations of a wireless HVAC system. In some implementations, a method includes determining that a thermostat associated with the property is presently unavailable to send or receive a wireless communication; obtaining temperature data collected by one or more sensors located at the property; identifying one or more models for temperature monitoring at the property; determining an operation to be performed by an HVAC system based on the temperature data and the one or more models; and providing data indicating the operation to the HVAC system.
    Type: Application
    Filed: March 9, 2023
    Publication date: September 14, 2023
    Inventors: Jackson Alexander Klein, Craig Carl Heffernan, Daniel Marc Goodman, Andrew Tekle-Shirley, Robert Nathan Picardi, Liam Shea Daly, Grant Rudd
  • Publication number: 20230257619
    Abstract: A novel reaction resin formulation having a significantly improved properties profile contains crosslinkers, monomers, urethane methacrylates, prepolymers, optional further auxiliaries, and a curing system containing permaleinates and a tertiary organic phosphite. The reaction resin formulation is useful for marking driving surfaces or coating surfaces. The reaction resins, above all based on a novel curing system, show an improved combination of higher long-term storage stability, improved toxicological profile, reduced curing time, a low yellowing tendency and a better colour fastness.
    Type: Application
    Filed: June 1, 2021
    Publication date: August 17, 2023
    Applicant: Röhm GmbH
    Inventors: Janos Lotz, Alexander Klein
  • Publication number: 20230183405
    Abstract: Free radical-curing (meth)acrylate resins contain stabilizers and acidic adhesion promoters. The (meth)acrylate resins are characterized by particularly high storage stability, even at relatively high temperatures, and a concomitant increase in the activity of the accelerator present in the (meth)acrylate resin. The special stabilizers increase the storage stability, give rise to a rapid cure rate, and make the curing properties insensitive to the acidic adhesion promoters present alongside them. This makes it possible for very good adhesion to a wide variety of materials and thus a broader field of use.
    Type: Application
    Filed: April 15, 2021
    Publication date: June 15, 2023
    Applicant: Röhm GmbH
    Inventors: Alexander KLEIN, Janos LOTZ
  • Publication number: 20230174799
    Abstract: A novel reaction system can be used for intumescent coating. Intumescent coatings are used in particular for the protection of metallic building components, such as girders in building construction. In the event of a fire, such coatings undergo reactive foaming that results in the formation on the metal girder of a fireproof insulating layer having low thermal conductivity and, through the insulation that this creates, retards any early, thermal-induced failure of the building component. Resin systems having improved low-temperature flexibility can be used to ensure good metal adhesion and impact resistance even at low temperatures, while avoiding the polymer components that are otherwise customary in resin systems.
    Type: Application
    Filed: April 15, 2021
    Publication date: June 8, 2023
    Applicant: Röhm GmbH
    Inventors: Alexander Klein, Janos Lotz
  • Patent number: 11598035
    Abstract: An apparatus for making nonwoven from continuous filaments has a spinner for spinning the filaments, a cooler for cooling the spun filaments, and a mesh belt that moves in a generally horizontal travel direction and that passes through a deposition location where the spun and cooled filaments are deposited on the mesh belt to form thereon a nonwoven web. A nose roller defines a deflection zone over which the mesh belt is deflected from its travel direction downstream of the deposition location. At least one lift roller above the mesh belt downstream of the deposition location separates the nonwoven web from the mesh belt at a separation location at a first spacing upstream from the deflection zone of the nose roller. A treatment device for the nonwoven web is provided downstream of the mesh belt in the travel direction and receiving the nonwoven web from the lift roller.
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: March 7, 2023
    Assignee: REIFENHAEUSER GMBH & CO. KG MASCHINENFABRIK
    Inventors: Tobias Wagner, Dirk Buettner, Alexander Klein
  • Publication number: 20230043804
    Abstract: A reactive mixture comprising a Fire, Smoke and Toxicity retardant (FST) composition for making a polyisocyanurate and/or polyurethane (PIR/PUR) comprising material, said FST composition comprising: a) at least one compound having at least one ethylenically unsaturated moiety having a number average equivalent weight<160 g/mol, and b) optionally one or more radical initiator compound characterized in that the onset temperature for radical polymerization (Tonset) of the ethylenically unsaturated compound with or without the radical initiator is 2° C. up to 40° C. lower than the maximum reaction temperature achieved during the process for making the PIR/PUR material (reaction exotherm (Treaction)).
    Type: Application
    Filed: December 22, 2020
    Publication date: February 9, 2023
    Applicant: Huntsman International LLC
    Inventors: Rene Alexander Klein, Nima Esmaeili, Nadja Kathrin Richter, Rajesh Kumar Gajendran, Xiaodong Guo, Thomas Julien Joncheray, Jan Vandenbroeck
  • Publication number: 20230021509
    Abstract: A polyisocyanurate and/or polyurethane (PIR/PUR) comprising material having improved Flame, Smoke and/or Toxicity (FST) retardancy is disclosed and a method for forming said PIR/PUR comprising material. The PIR/PUR material is comprising at least 0.2 wt % of compounds having a number average equivalent weight <160 g/mol and at least one non-polymerized ethylenically unsaturated moiety based on the total weight of the PIR/PUR comprising material, and optionally 0.01 wt % up to 1 wt % of one or more radical initiator compounds based on the total weight of the PIR/PUR comprising material.
    Type: Application
    Filed: December 22, 2020
    Publication date: January 26, 2023
    Applicant: Huntsman International LLC
    Inventors: Rene Alexander Klein, Nima Esmaeili, Nadja Kathrin Richter, Rajesh Kumar Gajendran, Xiaodong GUO, Thomas Julien Joncheray, Jan Vandenbroeck
  • Publication number: 20220363858
    Abstract: A reactive mixture and method for making a thermoplastic polyurethane (TPU) flexible foam having a predominantly open-cell structure (open-cell content of ?50% by volume calculated on the total volume of the foam and measured according to ASTM D6226-10) and an apparent density below 200 kg/m3.
    Type: Application
    Filed: November 9, 2020
    Publication date: November 17, 2022
    Applicant: Huntsman International LLC
    Inventors: Jan Vandenbroeck, Steve Andre Woutters, Rajesh Kumar Gajendran, Martino Dossi, Rene Alexander Klein, Mark Joseph Brennan
  • Publication number: 20220154375
    Abstract: An apparatus for making nonwoven from continuous filaments has a spinner for spinning the filaments, a cooler for cooling the spun filaments, and a mesh belt that moves in a generally horizontal travel direction and that passes through a deposition location where the spun and cooled filaments are deposited on the mesh belt to form thereon a nonwoven web. A nose roller defines a deflection zone over which the mesh belt is deflected from its travel direction downstream of the deposition location. At least one lift roller above the mesh belt downstream of the deposition location separates the nonwoven web from the mesh belt at a separation location at a first spacing upstream from the deflection zone of the nose roller. A treatment device for the nonwoven web is provided downstream of the mesh belt in the travel direction and receiving the nonwoven web from the lift roller.
    Type: Application
    Filed: November 19, 2021
    Publication date: May 19, 2022
    Inventors: Tobias WAGNER, Dirk BUETTNER, Alexander KLEIN
  • Publication number: 20220120619
    Abstract: Described herein is a detector for detecting optical radiation, especially within the infrared spectral range, specifically with regard to sensing at least one of transmissivity, absorption, emission and reflectivity, being capable of avoiding or diminishing a cross detection between sensor areas, specifically between adjacent sensor areas, thus, avoiding or diminishing a deterioration of a measurement based on the at least one sensor signal.
    Type: Application
    Filed: January 28, 2020
    Publication date: April 21, 2022
    Inventors: Sebastian Valouch, Alexander Klein, Sebastian Mueller, Wilfried Hermes, Robert Send
  • Patent number: 11279832
    Abstract: This invention is directed to a polymerizable, cold-curing (meth)acrylate system for floor coating.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: March 22, 2022
    Assignees: Roehm GmbH, Evonik Corporation
    Inventors: William G. Heiber, Levi F. Scott, Oliver Schmidt, Alexander Klein