Patents by Inventor Alexandre Richez

Alexandre Richez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180195950
    Abstract: A flow cell package includes first and second surface-modified patterned wafers and a spacer layer. The first surface-modified patterned wafer includes first depressions separated by first interstitial regions, a first functionalized molecule bound to a first silane or silane derivative in at least some of the first depressions, and a first primer grafted to the first functionalized molecule in the at least some of the first depressions. The second surface-modified patterned wafer includes second depressions separated by second interstitial regions, a second functionalized molecule bound to a second silane or silane derivative in at least some of the second depressions, and a second primer grafted to the second functionalized molecule in the at least some of the second depressions. The spacer layer bonds at least some first interstitial regions to at least some second interstitial regions, and at least partially defines respective fluidic chambers of the flow cell package.
    Type: Application
    Filed: December 20, 2017
    Publication date: July 12, 2018
    Inventors: James Tsay, Anmiv Prabhu, David Heiner, Edwin Li, Alexandre Richez, John M. Beierle, Kevan Samiee, Kristina Munoz, Leonid Malevanchik, Ludovic Vincent, Naiqian Zhan, Peyton Shieh, Robert Yang, Samantha Schmitt, Sang Park, Scott Bailey, Sean M. Ramirez, Sunmin Ahn, Valerie Uzzell, Wei Wei, Yuxiang Huang, Tyler Jamison Dill
  • Publication number: 20180179575
    Abstract: An example of an array includes a support, a cross-linked epoxy polyhedral oligomeric silsesquioxane (POSS) resin film on a surface of the support, and a patterned hydrophobic polymer layer on the cross-linked epoxy POSS resin film. The patterned hydrophobic polymer layer defines exposed discrete areas of the cross-linked epoxy POSS resin film, and a polymer coating is attached to the exposed discrete areas. Another example of an array includes a support, a modified epoxy POSS resin film on a surface of the support, and a patterned hydrophobic polymer layer on the modified epoxy POSS resin film. The modified epoxy POSS resin film includes a polymer growth initiation site, and the patterned hydrophobic polymer layer defines exposed discrete areas of the modified epoxy POSS resin film. A polymer brush is attached to the polymer growth initiation site in the exposed discrete areas.
    Type: Application
    Filed: December 20, 2017
    Publication date: June 28, 2018
    Inventors: Wayne N. George, Alexandre Richez, M. Shane Bowen, Andrew A. Brown, Dajun M. Yuan, Audrey Rose Zak, Sean M. Ramirez, Raymond Campos
  • Publication number: 20180178416
    Abstract: An imprinting apparatus includes a silicon master having a plurality of nanofeatures defined therein. An anti-stick layer coats the silicon master, the anti-stick layer including a molecule having a cyclosiloxane with at least one silane functional group. A method includes forming a master template by: depositing a formulation on a silicon master including a plurality of nanofeatures defined therein, the formulation including a solvent and a molecule having a cyclosiloxane with at least one silane functional group; and curing the formulation, thereby forming an anti-stick layer on the silicon master, the anti-stick layer including the molecule. The method further includes depositing a silicon-based working stamp material on the anti-stick layer of the master template; curing the silicon-based working stamp material to form a working stamp including a negative replica of the plurality of nanofeatures; and releasing the working stamp from the master template.
    Type: Application
    Filed: December 19, 2017
    Publication date: June 28, 2018
    Inventors: Alexandre Richez, Andrew A. Brown, Julia Morrison, Wayne N. George, Timothy J. Merkel, Audrey Rose Zak
  • Publication number: 20180155469
    Abstract: Some embodiments described herein relate to new polymer coatings for surface functionalization and new processes for grafting pre-grafted DNA-copolymers to surface(s) of substrates for use in DNA sequencing and other diagnostic applications.
    Type: Application
    Filed: November 10, 2017
    Publication date: June 7, 2018
    Inventors: Andrew A. Brown, Wayne N. George, Alexandre Richez, Anne-Cecile Dingwall, Xavier von Hatten
  • Patent number: 9982250
    Abstract: Some embodiments described herein relate to a substrate comprising a silane functionalized surface for reversibly immobilizing a biological molecule of interest, such as oligonucleotides, polynucleotides, or protein. Methods for immobilizing the biological molecule and the use in DNA sequencing and other diagnostic applications are also disclosed.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: May 29, 2018
    Assignee: Illumina Cambridge Limited
    Inventors: Xavier von Hatten, Wayne N. George, Alexandre Richez, Anne-Cecile Dingwall, Andrew A. Brown
  • Patent number: 9868803
    Abstract: This invention relates to colored polymer, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: January 16, 2018
    Assignee: Merck Patent GmbH
    Inventors: Louise Diane Farrand, Nils Greinert, Claire Topping, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez, Simone Stuart-Cole
  • Patent number: 9815916
    Abstract: Some embodiments described herein relate to new polymer coatings for surface functionalization and new processes for grafting pre-grafted DNA-copolymers to surface(s) of substrates for use in DNA sequencing and other diagnostic applications.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: November 14, 2017
    Assignee: ILLUMINA CAMBRIDGE LIMITED
    Inventors: Andrew A. Brown, Wayne N. George, Alexandre Richez, Anne-Cecile Dingwall, Xavier von Hatten
  • Patent number: 9651846
    Abstract: This invention relates to particles for electrophoretic displays, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: May 16, 2017
    Assignee: Merck Patent GmbH
    Inventors: Louise Diane Farrand, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez, Simone Stuart-Cole
  • Patent number: 9645416
    Abstract: This invention relates to particles comprising a core particle and a polymeric shell, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: May 9, 2017
    Assignee: Merck Patent GmbH
    Inventors: Lewis Blackman, Louise Diane Farrand, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez
  • Patent number: 9588357
    Abstract: This invention relates to particles comprising a pigment core particle encapsulated by a polymer, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: March 7, 2017
    Assignee: Merck Patent GmbH
    Inventors: Lewis Blackman, Louise Diane Farrand, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez
  • Publication number: 20160122816
    Abstract: Some embodiments described herein relate to new polymer coatings for surface functionalization and new processes for grafting pre-grafted DNA-copolymers to surface(s) of substrates for use in DNA sequencing and other diagnostic applications.
    Type: Application
    Filed: October 29, 2015
    Publication date: May 5, 2016
    Inventors: Andrew A. Brown, Wayne N. George, Alexandre Richez, Anne-Cecile Dingwall, Xavier von Hatten
  • Publication number: 20160053252
    Abstract: Some embodiments described herein relate to a substrate comprising a silane functionalized surface for reversibly immobilizing a biological molecule of interest, such as oligonucleotides, polynucleotides, or protein. Methods for immobilizing the biological molecule and the use in DNA sequencing and other diagnostic applications are also disclosed.
    Type: Application
    Filed: August 20, 2015
    Publication date: February 25, 2016
    Inventors: Xavier von Hatten, Wayne N. George, Alexandre Richez, Anne-Cecile Dingwall, Andrew A. Brown
  • Publication number: 20150168746
    Abstract: This invention relates to particles comprising a pigment core particle encapsulated by a polymer, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Application
    Filed: May 7, 2013
    Publication date: June 18, 2015
    Inventors: Lewis Blackman, Louise Diane Farrand, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez
  • Publication number: 20150129818
    Abstract: This invention relates to particles comprising a core particle and a polymeric shell, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Application
    Filed: May 7, 2013
    Publication date: May 14, 2015
    Inventors: Lewis Blackman, Louise Diane Farrand, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez
  • Publication number: 20150126680
    Abstract: This invention relates to particles comprising a core particle and a polymeric shell, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Application
    Filed: May 7, 2013
    Publication date: May 7, 2015
    Applicant: Merck Patent GmbH
    Inventors: Louise Diane Farrand, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez, Simone Stuart-Cole
  • Publication number: 20150123049
    Abstract: This invention relates to particles for electrophoretic displays, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Application
    Filed: May 7, 2013
    Publication date: May 7, 2015
    Inventors: Louise Diane Farrand, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez, Simone Stuart-Cole
  • Publication number: 20150099119
    Abstract: This invention relates to coloured polymer, a process for their preparation, electrophoretic fluids comprising such particles, and electrophoretic display devices comprising such fluids.
    Type: Application
    Filed: May 7, 2013
    Publication date: April 9, 2015
    Inventors: Louise Diane Farrand, Nils Greinert, Claire Topping, Jonathan Henry Wilson, Simon Biggs, Olivier Cayre, Simon Lawson, Alexandre Richez, Simone Stuart-Cole