Abstract: The present application relates to a gRNA targeting CYP4V2 gene, and a donor nucleic acid molecule comprising a CYP4V2 gene fragment. The present application also relates to use of the gRNA and the donor nucleic acid molecule in the preparation of a medicament for treating Bietti crystalline dystrophy.

Abstract: A brain wave induction method is provided. In the method, a first sound wave to a left ear of a user and a second sound wave to a right ear of the user are simultaneously provided. There is a frequency difference between a first frequency of the first sound wave and a second frequency of the second sound wave. The frequency difference is automatically changed along with time.

Abstract: An apparatus for supplying power is disclosed. The apparatus may comprise a power supply circuit and a processing unit, wherein the power supply circuit may be connected with an electric energy input end of the processing unit, and the power supply circuit may provide a first power supply for the processing unit; and a forward voltage output end of the processing unit may provide a forward power supply, and a backward voltage output end of the processing end may provide a negative power supply, wherein the processing unit may include a resonant circuit, a first switching frequency of the processing unit may include a resonant frequency of the resonant circuit, and the resonant frequency may be outside an effective frequency range of a load of the apparatus for supplying power.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer-readable media that utilize machine learning to generate a sequence of transition frames for a gap in a clipped digital video. For example, the disclosed system receives a clipped digital video that includes a pre-cut frame prior to a gap in the clipped digital video and a post-cut frame following the gap in the clipped digital video. Moreover, the disclosed system utilizes a natural motion sequence model to generates a sequence of transition keypoint maps between the pre-cut frame and the post-cut frame. Furthermore, using a generative neural network, the disclosed system generates a sequence of transition frames for the gap in the clipped digital video from the sequence of transition keypoint maps.

Abstract: A cleaner system includes a cleaner and a cleaner station that performs a method for removing residual dust. The cleaner station is configured to suction dust stored in the cleaner. Residual dust in the cleaner station after suctioning dust in a dust bin of the cleaner is suctioned through a bypass hole that penetrates an outside and an inside of a suction tube.

Abstract: An assembly method for a deep in-situ high-fidelity coring calibration platform includes the following steps: S1: fixing a core bin assembly subsystem on a preset ground foundation and fixing a simulator of a core bin on a mounting base plate of the core bin assembly subsystem; S2: driving a cylinder and driving the mounting base plate to move to a preset position; S3: driving a servo motor and controlling two clips to move close to each other; S4: fixing a drill pipe bin assembly subsystem on the ground foundation; S5: assembling multiple sections of a drill pipe bin in turn; aligning and connecting a bottom of the drill pipe bin to the simulator, and aligning and communicating the top of the drill pipe bin with the lower part of an adaptive drill pipe guide structure; and S6: driving the adaptive drill pipe guide structure to perform accurate positioning.

Abstract: A cat litter box includes a shell assembly, a rotary drum, and a driving assembly. The shell assembly includes a top shell, a middle shell, and a bottom shell arranged in sequence in a vertical direction. An excrement collection compartment is arranged inside the bottom shell. The excrement collection compartment is arranged opposite to the middle shell. The top shell is detachably connected to the middle shell. The middle shell is detachably connected to the bottom shell. A mounting cavity is formed between the top shell and the middle shell. The rotary drum is rotatably arranged in the mounting cavity. The driving assembly is detachably connected to the middle shell, and includes a driving unit. The driving unit is drivingly connected to the rotary drum.

Abstract: Sidelink based communications include communications between equipment (“UE”) and/or with a basestation. The sidelink communications may include certain sidelink information from a communication device that includes UE information, positioning/location information, or other capabilities that are used for the sidelink communications. Sidelink information that is communicated through sidelink communications may be modified based on priority determinations or position reference signals (PRS). There may be a mapping or associating of configurations that are communicated through sidelink communications.

Abstract: Disclosed are a system and method of predicting sensitivity of Klebsiella against Cefoxitin, which belong to bioinformatics art. The system comprises a computer readable storage medium on which is stored a computer program. An Exp (?k) power value calculation method is implemented when the computer program is executed by a processor. The Exp(?k) power value calculation method comprises following computing steps: S1: k value is calculated according to formula I: k = 0.032 - 0.557 × ( C ? 1 - 1.008 0.317 ) + 0.054 × ( C ? 2 - 0.667 1.326 ) + 2.878 × ( C ? 3 - 0.552 1.121 ) + 1.021 × ( C ? 4 - 0.072 0.377 ) + 0.772 × ( C ? 5 - 0.036 0.292 ) Formula ? I S2: Exp(?k) power value with natural constant e as base and ?k as exponent is calculated; wherein, C1-C5 are respectively the number of ramA, sul1, KPC-1, DHA-1, bleomycin resistance determinant gene copies in the candidate Klebsiella strain.

Abstract: The present disclosure provides an electronic device including a first sensing unit, a first transistor coupled to the first sensing unit, a second transistor coupled to the first transistor, a second sensing unit, a third transistor coupled to the second sensing unit, a fourth transistor coupled to the third transistor, a first signal line coupled to the second transistor and the fourth transistor, and a power line coupled to the first transistor and the third transistor, in which the power line is disposed between the first sensing unit and the second sensing unit.

Abstract: Embodiments of the present disclosure provide a solution for processing video data. A method for processing video data is proposed. The method comprises: performing, during a conversion between a current block of a video and a bitstream of the video, an intra prediction for the current block based on at least one first parameter different from at least one second parameter used for an intra prediction of a normal angular mode, at least one extended angular mode being used for the current block; and performing the conversion based on the intra prediction mode. Compared with the conventional solution, the proposed method can advantageously improve the coding efficiency.

Abstract: A biphasic solvent system for converting biomass to prepare 2,5-hexanedione and a one-pot process for catalytically converting biomass to prepare 2,5-hexanedione with said biphasic solvent system are provided. The process includes the steps of contacting and reacting a biomass raw material with a hydrogenation catalyst using hydrogen gas as a hydrogen source in a heterogeneous system formed from an organic solvent, an inorganic salt and water to obtain 2,5-hexanedione. The hydrogenation catalyst includes a hydrogenation active component and a support. The support is selected from one or more of hydrophobic active carbon and graphene. The process can achieve efficient conversion of biomass without the participation of acid catalysts, and have a very high selectivity for the product 2,5-hexanedione.

Abstract: The present invention relates to the field of video image processing, and provides a filtering method and an apparatus, to resolve a problem that subjective quality and objective quality of an image deteriorate because filtering processing cannot be performed on internal blocks of a non-translational motion prediction unit.

Abstract: A sight includes a housing, a rangefinder assembly, a display screen provided in the housing and electrically connected to the rangefinder assembly, an objective lens set, an image inverter set, a reticle set, and an eyepiece set provided in the housing and sequentially arranged from an object side to an eye side, where the reticle set includes a first prism and a second prism cemented to each other, a reflective film is provided on a first cemented plane of the first prism and the second prism; the first prism has a first plane provided on an imaging plane; the second prism has a second plane perpendicular to the first plane; the first plane is provided with a reticle pattern; a light-emitting plane of the display screen is attached to the second plane; and the reflective film is configured to reflect light from the display screen to the eye side.

Abstract: Implementations of the present disclosure provide a method for transmitting data, an access network device and a terminal device. The method includes the following steps: an access network device receives a first data packet sent by a core network device, and determines a state that the terminal device needs to be in for receiving the first data packet, the state that the terminal device needs to be in for receiving the first data packet is any of at least two states, and the at least two states are different states when the terminal device is in data transmission with a network side device; the access network device sends the data packet to the terminal device. The implementations of the invention can enable the terminal device to transmit the data packet in a state matched with the data packet.

Abstract: A physical simulation method for a forging process of a nickel-base superalloy includes: subjecting a nickel-base superalloy sample to heating, heat preservation, and quenching successively to obtain a pretreated sample; and subjecting the pretreated sample to heating, first heat preservation, cooling, repeated compression-cooling treatments, second heat preservation, and quenching successively to obtain a simulated sample, where the compression-cooling treatments are repeated at least three times. In the physical simulation method, multi-pass compression-cooling deformation is adopted to simulate a forging process of a nickel-base superalloy, and this forging simulation method is close to an actual forging process, has an excellent simulation effect and high operability, and involves simple operations. The physical simulation method is suitable for a variety of nickel-base superalloys of a same forging method.

Abstract: Proposed are a two-dimensional vertical composite laminate including graphene and hexagonal boron nitride and a method of fabricating the same. The composite laminate includes a first layer and a second layer positioned on the first layer, in which the first layer includes a first boron nitride layer containing hexagonal boron nitride or a first graphene layer containing graphene, and the second layer includes a second boron nitride layer containing hexagonal boron nitride or a second graphene layer containing graphene. The composite laminate allows for the control of the twist angle and stacking order of each layer, so that the composite laminate can have the desired crystal structure, crystal thickness, and composition to exhibit novel physical properties.

Abstract: A conjugate may have formula (1), i.e., M-[(L1)a-(L2)b-(D)c] (1), wherein M is a biological macromolecule having a nucleophilic functional group, M is linked to L1 with the nucleophilic functional of M, D is a functional molecule, L2 is a linker, and L1 is a compound of formula 1 wherein R is —F or —OH, and L2 is linked to R1, R3 or R2, a is an integer of 1 to 10, b, c is each independently an integer of 0 to 10, provided that b and c are not simultaneously 0. R1, R2, and R3, may independently be H, optionally substituted alkyl, or optionally substituted aryl, and R1, may be H or isotope thereof ? C may link R1 and a C linking R2 form a ring.

Abstract: A meta fluorescence tissue mimicking phantom of imaging method and system. The system includes a fluorescence acquisition module configured to acquire spectral information, contrast information and light intensity information of fluorescence molecules in biological tissue, store the spectral information, the contrast information and the light intensity information in a computer, and transmit the spectral information, the contrast information and the light intensity information to a fluorescence reproduction module through a computer communication port; a fluorescence reproduction module configured to generate a fluorescence tissue mimicking phantom according to the spectral information, the contrast information and the light intensity information; and a meta fluorescence tissue-mimicking phantom imaging module configured to perform imaging on the fluorescence tissue mimicking phantom.

Abstract: A display panel includes: a driving substrate, a pixel definition layer, multiple light-emitting elements, a first encapsulation layer, a transparent heat insulation layer, a pixel isolation structure and a color conversion layer. The pixel definition layer includes multiple first pixel partitions arranged in an array form, and multiple first pixel regions are enclosed by adjacent first pixel partitions. The transparent heat insulation layer is arranged on a side of the first encapsulation layer away from the driving substrate, an orthographic projection of the transparent heat insulation layer onto the driving substrate at least covers an orthographic projection of each first pixel region onto the driving substrate. The pixel isolation structure includes multiple second pixel partitions arranged in an array form, multiple second pixel regions are enclosed by adjacent second pixel partitions.