Abstract: The present invention provides a compound, preferably a peptide, having the following characteristics: a) consisting of 9 amino acids in a linear arrangement; b) of those 9 amino acids, 5 are cationic and 4 have a lipophilic R group; c) at least one of said 9 amino acids is a non-genetically coded amino acid (e.g. a modified derivative of a genetically coded amino acid); and optionally d) the lipophilic and cationic residues are arranged such that there are no more than two of either type of residue adjacent to one another; and further optionally e) the molecule comprises two pairs of adjacent cationic amino acids and one or two pairs of adjacent lipophilic residues; for use in the treatment of a tumour by combined, sequential or separate administration with an immune checkpoint inhibitor. The present invention further provides pharmaceutical packs or compositions comprising these active agents and methods of treating a tumour comprising administration of these active agents.

Abstract: A guide rail for an elevator system has an elongate length with a cross-section perpendicular to the length; the cross-section including a base section for mounting to a wall of a hoistway, and a blade section extending from the base section; the blade section including a guide surface for interacting with a guide element of a component movable in the elevator hoistway; the guide rail including: a pair of separate rail piece parts fixed together to form the guide rail; the pair of separate rail piece parts including a first rail piece part and a second rail piece part; the first rail piece part being formed from a first thickness of sheet material bent to have a cross-section of a first predetermined shape, and the second rail piece part being formed from a second thickness of sheet material bent to have a cross-section of a second predetermined shape.

Abstract: A catheter includes a shaft, an expandable frame, a first set of electrodes, and a second set of electrodes. The shaft is configured for insertion into an organ of a patient. The expandable frame is fitted at a distal end of the shaft. The first set of electrodes is disposed over a distal portion of the expandable frame, and configured to be placed in contact with a tissue in the organ. The second set of electrodes is disposed on a proximal portion of the expandable frame, and configured to be inter-connected to form a common electrode.

Abstract: A drug delivery assembly comprising an indicator adapted to move during expelling of a dose amount of drug, the amount of movement being indicative of the size of the expelled dose amount, and electronic tracking sensor circuitry adapted to with pre-determined intervals to change the operative state from a sleep state to a low-power detection state and back to the sleep state. When in the detection state, the electronic sensor circuitry is adapted to detect motion of an activation component, and if motion of the activation component is detected, then change the operative state from the low-power detection state to a high-power measuring state in which the amount of motion of the indicator relative to the tracking means can be determined.

Abstract: A method for fine-tuning a variable-gear steering column according to a speed of the vehicle, the method includes: a step of characterizing a desired handling of the vehicle for a speed V1 and of characterizing a desired stability for a speed V2; a step of determining a value G1 of the gear ratio allowing obtaining the desired handling at the speed V1, and a value G2 of the gear ratio allowing obtaining the desired stability at the speed V2, a step of calculating a parameter p1 and a parameter p2 according to the speed V1, the speed V2, the value G1 and the value G2 so that the relationship between the gear ratio and the speed of the vehicle is defined by the equation G=p2+p1/V, when the speed is included between a first threshold and a second threshold.

Abstract: Systems and methods include reception of an instruction to recover a first database tenant of a first database instance to a first point in time, the first database tenant associated with first database artifacts of the first database instance, and the first database instance including two or more database tenants and, in response to the instruction, creation of a second database instance, selection of backup data of the first database instance based on the first point in time, execution of a recovery of the backup data on the second database instance, export of second database artifacts of the first database tenant from the second database instance to a storage, truncation of the first database artifacts from the first database instance, import of the second database artifacts from the storage to the first database instance, and deletion of the second database instance.

Abstract: An irrigation system for a vertical farm system including one or more irrigation stations, each of the one or more irrigation stations including one or more tanks that hold irrigation fluid, and one or more spigots that deliver the irrigation fluid from the one or more tanks to the vertical farm system. Each of the one or more irrigation stations includes a plurality of sub-assemblies, and each sub-assembly includes a corresponding one of the one or more tanks and a corresponding one of the one or more spigots.

Abstract: The invention relates to a solid composition comprising at least 90.0 wt. % bis(2-hydroxyethyl) terephthalate (BHET), as based on dry weight and having a pore volume in the range of 0.20 to 1.0 cm3/g. The porosity is above 25% or even above 35%. The solid composition is made by crystallisation, followed by granulation and fluid bed drying.

Abstract: A substrate holder including: a main body having a main body surface; a plurality of burls projecting from the main body surface and configured for supporting the substrate; and an edge seal projecting from the main body surface, wherein: the edge seal is spaced apart from the plurality of burls so as to define a gap therebetween, the gap having a width greater than or equal to about 75% of a pitch of the plurality of burls; the plurality of burls includes a first group of burls and a second group of burls surrounding the first group of burls; and the stiffness in the direction perpendicular to the support plane per unit area of the second group of burls is greater than or equal to about 150% of the stiffness in the direction perpendicular to the support plane per unit area of the first group of burls.

Abstract: The invention relates to a measurement body for checking geometric deviations in a 3-axis machine tool comprising a base plate, a first wall which protrudes perpendicularly from the base plate, a second wall which protrudes perpendicularly from the base plate and is arranged perpendicularly to the first wall. A first row of holes and a second row of holes are formed in the base plate. The first wall is a stepped triangle and comprises a step-shaped region having a plurality of steps, on an upper, exposed region. The second wall is a square wall and comprises a first row of wall holes on an upper, exposed region which extends in parallel with the base plate. The first row of holes is arranged in parallel with the row of step holes and the second row of holes is arranged in parallel with the first row of wall holes.

Abstract: The present disclosure relates to thermal cracking a renewable stabilized naphtha-range hydrocarbon feed and a cracking effluent. A method includes providing a renewable stabilized naphtha-range hydrocarbon feed; thermally cracking the renewable stabilized naphtha-range hydrocarbon feed in a thermal cracking furnace, optionally together with co-feed(s) and/or additive(s); and subjecting the effluent of the thermal cracking furnace to a separation treatment to provide at least a light olefin(s) fraction.

Abstract: A computing system is provided, including one or more processing devices. The one or more processing devices are configured to receive quantum circuit parameters including a code parameter of an error correction code and a number of T gates included in a quantum circuit. The one or more processing devices are further configured to receive respective decoder parameters of each of a plurality of candidate decoders. The decoder parameters include a physical noise rate of a plurality of physical qubits at which the quantum circuit is configured to be executed and a stopping time of the candidate decoder. The one or more processing devices are further configured to compute respective spacetime costs of the candidate decoders based on the quantum circuit parameters and the decoder parameters. The one or more processing devices are further configured to output a selection of a lowest-spacetime-cost decoder for implementation at a quantum computing device.

Abstract: An ink composition for additive manufacturing comprises at least a first phase, the first phase being a liquid phase, and inorganic particles being distributed in the first phase. The inorganic particles are redox active. The first phase furthermore comprises at least one organic processing additive. In a method of additive manufacturing a structure for use in a thermochemical fuel production process and/or in a heat transfer application, said ink composition is deposited so as to form a precursor structure, and said precursor structure is subjected to at least one thermal treatment so as to form the structure for use in the thermochemical fuel production process and/or in the heat transfer application.

Abstract: An operating console of a medical device has input elements configured to generate electrical control signals as a result of actuation of the input elements by an operator of the medical device. The operating console has an analysis apparatus, which is connected to the input elements to receive the electrical control signals. The analysis apparatus is configured to determine control commands configured to drive the medical device based on the electrical control signals. It has an interface configured to output the control commands to the medical device. The operating console has a number of sensors configured to detect electromagnetic interference signals from the area surrounding the operating console. The analysis apparatus is connected to the sensors to receive characteristic quantities for the electromagnetic interference signals detected by the sensors. It is configured to process the characteristic quantities.

Abstract: The present disclosure relates to a protective membrane system for a rod-shaped sensor. comprising a membrane unit which is resilient and has a lattice structure, and a secondary fastening unit which is suitable for fastening the membrane unit to a rod-shaped sensor.

Abstract: Disclosed herein are system, apparatus, article of manufacture, method and/or computer program product embodiments, and/or combinations and sub-combinations thereof, for ad insertion by a display device coupled to a media device via a high-definition media interface (HDMI) connection, where the media device provides media content and/or a control signal. When the media device pauses the media content, the display device can determine that a pause event has occurred and insert an ad shown on the display device. Further, some embodiments include determining the context and/or content of the media content that is paused, and determining an ad that is customized to the determined context and/or content to be displayed on the display device. In some embodiments, the display device can determine additional information from the control signal that may also be used to determine the ad to be displayed on the display device.

Abstract: It is an object of the present invention a garment ironing system. Said system comprises a control unit (1) configured to operate in coordination: an operating unit (2), defining an operation space adapted to receive at least one garment and programmed to perform an ironing task; and a transport unit (3) designed to convey the garment from a position outside the operation space to the interior of the operation space, where the ironing task will be performed.