Abstract: A method for setting an ergonomic position of a center console with an arm rest and with one or more operating elements separate from the arm rest in a vehicle, includes detecting an arm of a driver facing the centre console with a forearm and at least areas of an upper arm using one or more optical sensors; determining at least an elbow position and a hand position of the arm of the driver using sensor data of the sensors by means of a suitable evaluation method; and automatically moving the arm rest of the centre console using the positioning unit based on the determined elbow positions and hand positions at least vertical as well as parallel to the vehicle axis so that after moving an ergonomic position of the arm is achieved.

Abstract: The invention refers to a set of rear view assemblies (10) for a vehicle (20) comprising: at least one first rear view assembly (1) to be mounted to a driver side (21) of the vehicle (20) to observe traffic conditions behind on the driver side (21), comprising a first base assembly (1a) and a first head assembly (1b) mounted on the first base assembly (1a), where the first head assembly comprises a mirror element (4) having a first size being a minimum size still fulfilling the legal requirements for provided a mirror-based field of view (FOV-21) on the driver side (21); and at least one second rear view assembly (2) to be mounted on a passenger side (22) of the vehicle (20) to observe traffic conditions behind on the passenger side (22), comprising a second base assembly (2a) and a second head assembly (2b) mounted on the second base assembly (2a), where the second head assembly (2b) comprises a mirror element (4) having a second size being the same minimum size as one of the first head assembly (1b) of the

Abstract: A pivotable interior rearview device for a motor vehicle includes a mirror surface provided by at least one of a reflective element and a display element, a first sensor device suitable for a light propagation time measurement for detecting at least one gesture by a driver of the motor vehicle incidence of light on the mirror surface, a switching device for switching the display element on and off, a pivoting device for pivoting the mirror surface from a normal position into at least one dimming position in which dazzling of the driver by light reflected in the mirror surface is reduced, and a control unit for controlling at least one of the switching device and the pivoting device. A method of using the rearview device is also described.

Abstract: Provided herein are cell penetrating conjugates. The conjugates include a non-cell penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone, wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular delivery of the non-cell penetrating protein. Also provided are compositions and kits comprising the cojugates.

Abstract: The present invention relates to the field of perfumery. More particularly, it concerns compounds comprising at least one ?-thio carbonyl or nitrile moiety capable of liberating an active molecule selected from an ?,?-unsaturated ketone, aldehyde or nitrile. The present invention concerns also the use of said compounds in perfumery as well as the perfuming compositions or perfumed articles comprising the invention's compounds. (I) wherein: a) m represents an integer from 1 to 6; b) Pro represents a hydrogen atom or a group susceptible of generating an odoriferous ?,?-unsaturated ketone, aldehyde or nitrile and is represented by the formulae (II) or (II?) in which the wavy line indicates the location of the bond between said Pro and the sulfur atom S; and at least one of the Pro groups is of the formula (II) or (II?).

Abstract: Systems and methods are provided for generating a rear view image display for a motor vehicle. A rear view system includes an optical sensor disposed at the motor vehicle and configured to capture image data, a computational unit coupled to the optical sensor by a cable connection and configured to execute program instructions stored on a computer-readable medium to modify the image data for presentation, and a display device coupled to the computational unit and configured to receive the modified image data from the computational unit and display the modified image data to a driver of the motor vehicle. The computational unit is further configured to receive software calibration to optimize modification of the image data.

Abstract: An actuator mechanism for a rearview device includes a cam surface which is positioned on or is part of a rearview element or rearview element mount of the rearview device, a cam lever configured to move on the cam surface, an actuator configured to rotate the cam lever, where rotating the cam lever in one direction causes the rearview element or rearview element mount to move in one manner, and rotating the cam lever in an opposite direction causes the rearview element or rearview element mount to a move in a different manner. A rearview device and a motor vehicle may include the actuator mechanism.

Abstract: A rear view device for a motor vehicle includes a mirror base which is mountable on the vehicle and which supports a mirror head with a housing, the mirror head being movable relative to the mirror base using at least one power-fold unit, and includes at least one support or housing element for mounting at least a part of the power-fold unit in a mounting area. The at least one element may include at least one foamed polymer part at least partly within the mounting area. A motor vehicle may include such a rear view device.

Abstract: A method displays information graphically on an image captured by a vehicular optical system. The method includes capturing the image and identifying an object in the image. The method the assigns a priority level to the object based on a predetermined criterion. The object is altered based on its priority level to create an altered object. An altered object may have a changed color, a colored halo surrounding it, or a colored object inside it. Other possible ways to alter the way the object looks are possible. The altered object is displayed in the image in place of the object on a mobile device to alert a person of its presence and the priority level associated therewith.

Abstract: An illumination and image acquisition unit for movable mounting on a vehicle body includes a movable section having an image acquisition section with at least one camera, a lighting member having at least one light source and an end section, the at least one light source being a component of a side boundary light, an ambient lighting, a signal or warning light, a flasher, a camper light, a laser display, a logo lamp, a floor light, or a projector. A motor vehicle includes such a lighting and imaging unit.

Abstract: An antibody specifically recognizing human tumor necrosis factor 1 (hu TNFR1), for use in treating nonalcoholic steatohepatitis (NASH) and disease conditions associated thereto.

Abstract: A crimp assembly for electrically contacting a conductive component of an electrical cable includes an anvil bushing and a compression sleeve. The anvil bushing has a retention shoulder extending circumferentially on an outer peripheral surface of the anvil bushing and supporting a section of the conductive component. The compression sleeve has an inner diameter larger than an outer diameter of the retention shoulder.

Abstract: A cable retainer insert for a multi-strand cable includes a cable contact portion and a plurality of cable receptacles in the cable contact portion circumferentially spaced from each other. Each of the cable receptacles receives a strand of the multi-strand cable. Each of the cable receptacles has a cable strand insertion opening at a radially outward end and a bottom at an opposite radially inward end. A circle inscribed in each of the cable receptacles and touching the bottom of the cable receptacle extends radially outward beyond the cable strand insertion opening.

Abstract: Provided herein are, inter alia, nucleic acid-peptide conjugates including a non-cell penetrating protein (e.g., an Hdm2 targeting peptide) attached at its C-terminus to a phosphorothioate nucleic acid. Attachment of the phosphorothioate nucleic acid to the non-cell penetrating protein conveys stability to and allows for efficient intracellular delivery of the non-cell penetrating peptide. The nucleic acid-peptide conjugates provided herein including embodiments thereof are useful, inter alia, for the treatment of cancer.

Abstract: The present invention relates to a nanostructure comprising: a) a nucleic acid scaffold; and b) at least two peptide moieties, wherein the at least two peptide moieties specifically bind to a molecule expressed on the surface of a virus and are attached to the nucleic acid scaffold, wherein the structure of the nucleic acid scaffold is selected from the group of: i) a linear nucleic acid scaffold, wherein the at least two peptide moieties are each attached at or near different ends of the nucleic acid scaffold; and ii) a branched nucleic acid scaffold, wherein the at least two peptide moieties are each attached to a different branch of the scaffold. The invention furthermore relates to the nanostructure of the invention for use as a medicament, and more specifically for use in the treatment of viral infections. The invention also relates to the nanostructure of the invention for the use in diagnostic purposes and in methods of detecting whether a virus is present in a sample.

Abstract: Provided herein are, inter alia, nucleic acid-peptide conjugates including a non-cell penetrating protein attached at its C-terminus to a phosphorothioate nucleic acid. Attachment of the phosphorothioate nucleic acid to the non-cell penetrating protein conveys stability to and allows for efficient intracellular delivery of the non-cell penetrating peptide. The nucleic acid-peptide conjugates provided herein including embodiments thereof are useful, inter alia, for the treatment of cancer, inflammatory disease, pain, and viral infection.

Abstract: The invention provides for a RANKL-specific antagonistic agent recognizing human platelet-expressed receptor activator of nuclear factor kappa-B ligand (pRANKL), for use in treating a cancer patient to prevent or reduce premetastatic lesions in blood.

Abstract: Provided herein are, inter alia, nucleic acid conjugates including a non-cell penetrating ribonucleic acid compound attached at its 3? end to a phosphorothioate polymer. Attachment of the phosphorothioate polymer to the non-cell penetrating ribonucleic acid conveys stability to and allows for efficient intracellular delivery of the non-cell penetrating ribonucleic acid. The nucleic acid conjugates provided herein including embodiments thereof are useful, inter alia, for the treatment of cancer, inflammatory disease, and pain.

Abstract: Provided herein are cell penetrating conjugates. The conjugates include a non-cell penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone, wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular delivery of the non-cell penetrating protein. Also provided are compositions and kits comprising the cojugates.

Abstract: A multifunction lamp unit for a vehicle includes a housing, at least one light pipe together with at least one light source disposed at least partially within the housing, and a clear lens substantially enclosing the housing, the at least one light pipe and the at least one light source, the lens having an inner surface, an outer surface disposed opposite the inner surface and at least one of a continuous transparent and translucent coating on the outer surface.