Abstract: The present invention relates to a method for determining the condition of a biological fluid by recording the IR spectrum of a sample of the biological fluid. To this end, the biological fluid can be examined in its native form. The method of the invention is usable, for example, for detecting pathological conditions in organisms.

Abstract: A friction clutch for a driven element that is connected directly to a drive by means of a first friction-disk clutch and being capable of being matched to the speed of the drive. When the first friction-disk clutch is disengaged, the drive of the driven element is adjusted to a relatively low take-up speed by means of an eddy-current clutch which can be engaged by means of a second friction-disk clutch. The driven element is arranged on a shaft or axle, so that, when the first and second friction clutches are disengaged, the drive of the driven element can be adjusted to a further take-up speed by means of the friction of a roller bearing. The eddy-current clutch includes an eddy-current part and a permanent magnet part which can be moved relative to the eddy-current part.

Abstract: A spring arrangement for a vehicle, in particular a rail vehicle, with a first spring device and a second spring device, wherein the first spring device and the second spring device are mechanically arranged in series, and are designed to support a component of the vehicle on a further component of the vehicle in a support direction, the first spring device has a first transverse rigidity in a transverse direction running transverse to the support direction, the second spring device has a second rigidity in the transverse direction which is smaller than the first transverse rigidity. The first spring device and the second spring device are arranged nested in the support direction.

Abstract: The invention relates to a use of an activated polymer to separate a non-covalently associated polypeptide multimer comprising multiple polypeptide subunits into multiple polypeptide subunits.

Abstract: A method for controlling a partially unsynchronized manual transmission, which realizes the increase of a rotational speed of a transmission part to be synchronized during a gear change procedure by connecting one element of the transmission, via a shiftable clutch, to a drive motor and by making available to this drive motor the required rotational speed as well as the necessary torque at its output shaft. It is also provided that when the rotational speed and/or the torque made available by the drive motor is not sufficient to ensure the synchronization of the manual transmission within a fixed time period, a shifting strategy is pursued, which prevents an unintentional holding of the manual transmission in its neutral position or idle position.

Abstract: The invention relates to a device and a method for control of an automatic transmission (1) in a vehicle having one control unit (2) by which can be received signals produced by a transmission selector lever (7) and/or a first transmission control (8), the signals of the first transmission control (8) being bridgeable so that the automatic transmission (1) can be manually operated. In order to make possible operating the vehicle with low fuel consumption and great flexibility of the driver at the moment, it is provided that a manual operation of the automatic transmission (1) be possible only when the vehicle has a speed (v) lower than a predetermined speed limit.

Abstract: The invention relates to methods of preparing antibody fragments. The invention further relates to antibody fragments prepared by said methods. The invention further relates to antibody variable regions comprised in antibody fragments producible by said methods.

Abstract: A drive member for a water pump of a cooling water circuit of an internal combustion engine, including a drive wheel, a shaft which is coupled to the water pump, and an electromagnetically actuable frictional shift clutch for the transfer of torque between the drive wheel and the shaft. According to the invention, a transfer of torque to a driven wheel can be shifted by means of the frictional shift clutch.

Abstract: The present invention relates to compositions comprising polypeptides, especially polypeptides capable of specifically binding predetermined antigens. The polypeptide in the composition comprises at least two antigen binding sites. These at least two antigen binding sites are located on a single polypeptide chain. One of the at least two antigen binding sites specifically binds the human CD3 antigen. The polypeptide may exist in both monomeric form and multimeric form. The multimeric form of the polypeptide constitutes no more than 5% of the total weight of the combined monomeric and multimeric forms of said polypeptide.

Abstract: The present invention provides a pharmaceutical composition comprising a bispecific single chain antibody construct. Said bispecific single chain antibody construct is characterized to comprise or consist of at least two domains, whereby one of said at least two domains specifically binds to human EpCAM and comprises at least one CDR-H3 region comprising the amino acid sequence NXID antigen and a second domain binds to human CD3 antigen. The invention further provides a process for the production of the pharmaceutical composition of the invention, a method for the prevention, treatment or amelioration of a tumorous disease and the use of the disclosed bispecific single chain antibody construct and corresponding means in the prevention, treatment or amelioration of a tumorous disease.

Abstract: A method for transmitting a data word, according to which a codeword supply (CV) is provided, the number of individual codewords (C1 . . . C31) of the supply corresponding at least to the number of data positions (#1 . . . #31) of the data word (DW), the codewords being formed from a basic codeword (C1) by means of cyclical shifting, and the cross correlation function of each codeword (C2 . . . C31) with the basic codeword (C1) having a distinct extreme value, the position of which is characteristic of the individual codeword (C2). An individual codeword (C1) which is combined with the respective date (0) of the data position (#5) so as to obtain a combined result (VE5) relating to the individual data positions, is assigned to each data position (#1) of the data word (DW). The combined results (VE1 . . .

Abstract: A friction clutch for a driven element that is connected directly to a drive by means of a first friction-disk clutch and being capable of being matched to the speed of the drive. When the first friction-disk clutch is disengaged, the drive of the driven element is adjusted to a relatively low take-up speed by means of an eddy-current clutch which can be engaged by means of a second friction-disk clutch. The driven element is arranged on a shaft or axle, so that, when the first and second friction clutches are disengaged, the drive of the driven element can be adjusted to a further take-up speed by means of the friction of a roller bearing. The eddy-current clutch includes an eddy-current part and a permanent magnet part which can be moved relative to the eddy-current part.

Abstract: The invention relates to an efficient process and device for the decontamination of waters polluted with heavy metals, semimetals and/or radionuclides by cation exchange and electrochemical deposition of the anions.

Abstract: A hand power tool (10) with a housing (12) that accommodates a turnably driveable driven shaft (20) on which a machining, in particular disk-shaped, replaceably clampable tool is mounted, whereby the driven shaft (20) is capable of being stopped by means of an axially displaceable locking pin (36) that extends through a through hole of the housing (12) and is capable of being operated from the outside, said hand power tool being made more robust and more cost-effective to produce due to the fact that the diameter-length ratio of the through hole (35) and the locking pin (36) is less than 1.8 and, in particular, equal to 1.5.

Abstract: A process for the preparation of L-amino acids, in which the following steps are carried out: (a) fermentation of the coryneform bacteria which produce the desired L-amino acid and in which at least the gene which codes for trehalose phosphatase and/or the gene which codes for maltooligosyl-trehalose synthase and/or the gene which codes for maltooligosyl-trehalose trehalohydrolase is or are attenuated, (b) concentration of the desired L-amino acid in the medium or in the cells of the bacteria, and (c) isolation of the L-amino acid, and optionally bacteria in which further genes of the biosynthesis pathway of the desired L-amino acid are addtionally enhanced are employed, or bacteria in which the metabolic pathways which reduce the formation of the desired L-amino acid are at least partly eliminated are employed.

Abstract: A drive member (1) for a water pump of the cooling-water circuit of an internal combustion engine, with a drive wheel (7) and a shaft (4) which is coupled to the water pump, is proposed. According to the invention, for the transmission of torque between the drive wheel (7) and the shaft (4), an electromagnetically actuable friction-disk clutch (9, 10, 11, 12) and a second clutch device in the form of an eddy-current clutch (14) are provided, the latter taking up the shaft (4) when the friction-disk clutch is out of engagement. Moreover, a frictional shift clutch for a drive member of this type is proposed.

Abstract: The invention relates to novel recombinant fusion proteins containing a protein sequence having the biological activity of glucose dehydrogenase as one of its constituents and to their utilization for simple and efficient detection of any type of proteins/polypeptides in SDS-Page gels and for quick optimization of expression systems that can express the above-mentioned proteins/polypeptides.

Abstract: The present invention provides nucleotide sequences from Coryneform bacteria which code for the OtsA protein and processes for the fermentative preparation of amino acids using bacteria in which the otrA gene is attenuated.

Abstract: The invention relates to an efficient process and device for the decontamination of waters polluted with heavy metals, semimetals and/or radionuclides by cation exchange and electrochemical deposition of the anions.

Abstract: An eddy current coupling (4) is proposed, with a first movable coupling element (13) comprising an electrically conductive eddy current portion (16), in which eddy currents can form. Furthermore, the eddy current coupling has a second coupling element (10) which is movable relative to the first coupling element (13) and on which magnets (14) are arranged in such a way that, in the event of a relative movement of the first and second coupling elements (10, 13) with respect to one another, the magnets are led past the eddy current portion (16). The first and the second coupling element (10, 13) are separated at the eddy current portion (16) via an air gap (18). Magnetic conduction means (17, 17a) consisting of magnetically conductive material are provided in the eddy current portion (16).