Patents by Inventor Andres Fernandez

Andres Fernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEVICES AND METHODS FOR OLIGONUCLEIC ACID LIBRARY SYNTHESIS
    Publication number: 20230338913
    Abstract: Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
    Type: Application
    Filed: May 17, 2023
    Publication date: October 26, 2023
    Inventors: William BANYAI, Bill James PECK, Andres FERNANDEZ, Siyuan CHEN, Pierre INDERMUHLE, Eugene P. MARSH
  • METHODS AND DEVICES FOR DE NOVO OLIGONUCLEIC ACID ASSEMBLY
    Publication number: 20230331765
    Abstract: Methods and devices are provided herein for surfaces for de novo nucleic acid synthesis which provide for low error rates. In addition, methods and devices are provided herein for increased nucleic acid mass yield resulting from de novo nucleic acid synthesis.
    Type: Application
    Filed: May 17, 2023
    Publication date: October 19, 2023
    Inventors: Pierre F. INDERMUHLE, Eugene P. MARSH, Andres FERNANDEZ, William BANYAI, Bill J. PECK
  • Methods and devices for de novo oligonucleic acid assembly
    Patent number: 11697668
    Abstract: Methods and devices are provided herein for surfaces for de novo nucleic acid synthesis which provide for low error rates. In addition, methods and devices are provided herein for increased nucleic acid mass yield resulting from de novo nucleic acid synthesis.
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: July 11, 2023
    Inventors: Pierre F. Indermuhle, Eugene P. Marsh, Andres Fernandez, William Banyai, Bill J. Peck
  • DE NOVO SYNTHESIZED GENE LIBRARIES
    Publication number: 20230211308
    Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
    Type: Application
    Filed: December 16, 2022
    Publication date: July 6, 2023
    Inventors: William BANYAI, Bill James PECK, Andres FERNANDEZ, Siyuan CHEN, Pierre INDERMUHLE
  • Devices and methods for oligonucleic acid library synthesis
    Patent number: 11691118
    Abstract: Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: July 4, 2023
    Assignee: TWIST BIOSCIENCE CORPORATION
    Inventors: William Banyai, Bill James Peck, Andres Fernandez, Siyuan Chen, Pierre Indermuhle, Eugene P. Marsh
  • NANOELECTRIC DEVICES AND USE THEREOF
    Publication number: 20230175062
    Abstract: Provided herein are compositions, devices, systems and methods for single molecule sensing. Further provided are devices for nucleic acid sequencing. The compositions, devices, systems and methods described herein provide improved retrieval of biomolecule-based information.
    Type: Application
    Filed: December 7, 2022
    Publication date: June 8, 2023
    Inventors: Jeremy LACKEY, Andres FERNANDEZ, David DODD, Alexander GORYAYNOV
  • DE NOVO SYNTHESIZED GENE LIBRARIES
    Publication number: 20230086062
    Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
    Type: Application
    Filed: August 9, 2022
    Publication date: March 23, 2023
    Inventors: William BANYAI, Bill James PECK, Andres FERNANDEZ, Siyuan CHEN, Pierre INDERMUHLE
  • OPHTHALMIC PHARMACEUTICAL COMPOSITION AND USE THEREOF
    Publication number: 20230079395
    Abstract: The present invention relates to the field of pharmaceutical compositions for ocular diseases, in particular, retinal neurogenerative diseases. The invention provides pharmaceutical compositions to be applied topically in the eyes, including peptides and methods for preparing them thereof. This invention further relates to ophthalmic pharmaceutical composition for use in the topical eye treatment and/or prevention of a retinal neurodegenerative disease.
    Type: Application
    Filed: February 12, 2021
    Publication date: March 16, 2023
    Applicant: FERRER INTERNACIONAL, S.A.
    Inventors: Carmen LAGUNAS ARNAL, Andrés FERNÁNDEZ GARCÍA, Laurence LACHAMP, Roland CHÉRIF-CHEIKH, Fréderic LACOMBE
  • De novo synthesized gene libraries
    Patent number: 11559778
    Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: January 24, 2023
    Assignee: Twist Bioscience Corporation
    Inventors: William Banyai, Bill James Peck, Andres Fernandez, Siyuan Chen, Pierre Indermuhle
  • CELL FREE CLONING OF NUCLEIC ACIDS
    Publication number: 20220325276
    Abstract: Methods and devices for cell-free sorting and cloning of nucleic acid libraries are provided herein.
    Type: Application
    Filed: May 16, 2016
    Publication date: October 13, 2022
    Inventors: William BANYAI, Bill James PECK, Andres FERNANDEZ, Siyuan CHEN, Pierre INDERMUHLE, Cheng-Hsien WU, Esteban TORO
  • De novo synthesized gene libraries
    Patent number: 11452980
    Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
    Type: Grant
    Filed: January 8, 2020
    Date of Patent: September 27, 2022
    Assignee: Twist Bioscience Corporation
    Inventors: William Banyai, Bill James Peck, Andres Fernandez, Siyuan Chen, Pierre Indermuhle
  • DEVICES AND METHODS FOR SYNTHESIS
    Publication number: 20220064206
    Abstract: Provided herein are compositions, devices, systems and methods for electrochemical synthesis. Further provided are devices comprising addressable electrodes controlling polynucleotide synthesis (deprotection, extension, or cleavage, etc.) The compositions, devices, systems and methods described herein provide improved synthesis, storage, density, and retrieval of biomolecule-based information.
    Type: Application
    Filed: August 26, 2021
    Publication date: March 3, 2022
    Inventors: Andres FERNANDEZ, Eugene P. Marsh, Maryam HABIBIAN
  • De novo synthesized gene libraries
    Patent number: 11185837
    Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: November 30, 2021
    Assignee: Twist Bioscience Corporation
    Inventors: William Banyai, Bill James Peck, Andres Fernandez, Siyuan Chen, Pierre Indermuhle
  • FUNCTIONALIZED SURFACES AND PREPARATION THEREOF
    Publication number: 20210170356
    Abstract: Compositions, devices, methods and systems are provided for differential functionalization of a surface of a structure to support biopolymer synthesis. Provided herein are processes which include use of lamps, lasers, and/or microcontact printing to add functional groups to surfaces for the efficient and uniform synthesis of oligonucleic acids.
    Type: Application
    Filed: February 19, 2021
    Publication date: June 10, 2021
    Inventors: Bill James PECK, Pierre INDERMUHLE, Eugene P. MARSH, Andres FERNANDEZ, David STERN
  • Functionalized surfaces and preparation thereof
    Patent number: 10987648
    Abstract: Compositions, devices, methods and systems are provided for differential functionalization of a surface of a structure to support biopolymer synthesis. Provided herein are processes which include use of lamps, lasers, and/or microcontact printing to add functional groups to surfaces for the efficient and uniform synthesis of oligonucleic acids.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: April 27, 2021
    Assignee: Twist Bioscience Corporation
    Inventors: Bill James Peck, Pierre Indermuhle, Eugene P. Marsh, Andres Fernandez, David Stern
  • DEVICES AND METHODS FOR OLIGONUCLEIC ACID LIBRARY SYNTHESIS
    Publication number: 20200330953
    Abstract: Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
    Type: Application
    Filed: July 6, 2020
    Publication date: October 22, 2020
    Inventors: William BANYAI, Bill James PECK, Andres FERNANDEZ, Siyuan CHEN, Pierre INDERMUHLE, Eugene P. MARSH
  • METHODS AND DEVICES FOR DE NOVO OLIGONUCLEIC ACID ASSEMBLY
    Publication number: 20200299322
    Abstract: Methods and devices are provided herein for surfaces for de novo nucleic acid synthesis which provide for low error rates. In addition, methods and devices are provided herein for increased nucleic acid mass yield resulting from de novo nucleic acid synthesis.
    Type: Application
    Filed: April 21, 2020
    Publication date: September 24, 2020
    Inventors: Pierre F. Indermuhle, Eugene P. Marsh, Andres Fernandez, William Banyai, Bill J. Peck
  • De novo synthesized gene libraries
    Patent number: 10773232
    Abstract: De novo synthesized large libraries of nucleic acids are provided herein with low error rates. Further, devices for the manufacturing of high-quality building blocks, such as oligonucleotides, are described herein. Longer nucleic acids can be synthesized in parallel using microfluidic assemblies. Further, methods herein allow for the fast construction of large libraries of long, high-quality genes. Devices for the manufacturing of large libraries of long and high-quality nucleic acids are further described herein.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: September 15, 2020
    Assignee: Twist Bioscience Corporation
    Inventors: William Banyai, Bill James Peck, Andres Fernandez, Siyuan Chen, Pierre Indermuhle
  • Devices and methods for oligonucleic acid library synthesis
    Patent number: 10744477
    Abstract: Devices and methods for de novo synthesis of large and highly accurate libraries of oligonucleic acids are provided herein. Devices include structures having a main channel and microchannels, where the microchannels have a high surface area to volume ratio. Devices disclosed herein provide for de novo synthesis of oligonucleic acids having a low error rate.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: August 18, 2020
    Assignee: TWIST BIOSCIENCE CORPORATION
    Inventors: William Banyai, Bill James Peck, Andres Fernandez, Siyuan Chen, Pierre Indermuhle, Eugene P. Marsh
  • Methods and devices for de novo oligonucleic acid assembly
    Patent number: 10669304
    Abstract: Methods and devices are provided herein for surfaces for de novo nucleic acid synthesis which provide for low error rates. In addition, methods and devices are provided herein for increased nucleic acid mass yield resulting from de novo nucleic acid synthesis.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: June 2, 2020
    Assignee: TWIST BIOSCIENCE CORPORATION
    Inventors: Pierre F. Indermuhle, Eugene P. Marsh, Andres Fernandez, William Banyai, Bill J. Peck