Abstract: The titanium (IV) and iron (III) MOF solid MUV-17 (TiFe2), has general formula (1): [TiIVFeIII2(O)(L)2(X)3]S, where X is each equal or different selected from: O2?, OH?, H2O, F?, Cl?, Br?, I?, NO3?, ClO4?, BF4?, SCN?, OH?, CH3COO?, C5H7O2?, SO42? and CO32?, L is a tricarboxylic ligand and S is at least one molecule of a polar solvent selected from the group consisting of N,N?-dimethylformamide,N,N?-diethylformamide,N,N?-dimethylacetamide, N-methyl-2-pyrrolidone, methanol, ethanol, isopropanol, n-propanol, water and mixtures thereof. The titanium (IV) and iron (III) MOF solid has long-term catalytic activity for the degradation of toxic compounds. The method for obtaining them comprises dissolving the components under anaerobic conditions. The invention also relates to the use of the titanium (IV) and iron (III) MOF solid as an additive with detoxifying properties of toxic compounds.

Abstract: An orthodontic bracket and archform system that uses friction-free mechanics are disclosed. The archform can have a male fastener that can be retained within an orthodontic bracket. The orthodontic bracket can have varying locking mechanism, such as deflectable tabs, springs, locking pins, and others, that can cooperate with features of the male fastener to prevent sliding between the archform and the bracket.

Abstract: An orthodontic bracket and archform system that uses friction-free mechanics are disclosed. The archform can have a male fastener that can be retained within an orthodontic bracket. The orthodontic bracket can have varying locking mechanism, such as deflectable tabs, springs, locking pins, and others, that can cooperate with features of the male fastener to prevent sliding between the archform and the bracket.

Abstract: A system, apparatus, and method for physiological data collection, providing targeted content, and facilitating remote diagnostics. In one embodiment, a kiosk contains physiological data collection devices, electronic computing devices, and targeted-content display devices to automatically collect physiological data regarding a patient and display targeted content specifically tailored to that patient based on the collected data.

Abstract: The technology disclosed relates to a system and method for assigning participants to groups in a clinical trial. The system includes a federated server configured with group assignability data specifying a plurality of groups assignable to participants in a clinical trial and group distribution data specifying distribution of the participants into groups. The groups include at least one placebo group and one or more treatment groups. The system includes an intervention server configured to generate group encryption keys for encrypting the group assignability data. The system includes edge devices of each of the participants. The edge devices are in communication with the federated server.

Abstract: A technique for data sharing among multiple filers that share a volume in a private or public cloud object store is implemented. In this approach, a mechanism is provided to enable a local filer to determine whether other filers that are sharing the volume have a consistent view of new data being written to the cloud object store by the local filer. The begins by associating together a collection of one or more files in a “push class.” On demand, a push operation for the push class is initiated on the local filer. Preferably, the push is managed according to one or more push criteria associated with the push class. Typically, the push operation pushes file data and metadata associated with the one or more files of the push class in respective phases, with the file data being pushed to the cloud during a first phase and the metadata associated with that file data being pushed during a second phase that follows the first phase.

Abstract: Systems and methods for patient monitoring and repositioning are provided. The system includes a mattress with a cell array and a base board array to receive the cell array. The cell array includes a plurality of individually height-adjustable cells each having sensor surface configured to sense at least one biomarker of the patient while lying on the mattress. The system also includes a main unit in communication with each cell of the cell array through the base board array. The main unit is configured to receive data from each of the cells, including measurements of the at least one biomarker, and independently control a height of each of the cells.

Abstract: The technology disclosed relates to a system and method for assigning participants to groups in a clinical trial. The system includes a federated server configured with group assignability data specifying a plurality of groups assignable to participants in a clinical trial and group distribution data specifying distribution of the participants into groups. The groups include at least one placebo group and one or more treatment groups. The system includes an intervention server configured to generate group encryption keys for encrypting the group assignability data. The system includes edge devices of each of the participants. The edge devices are in communication with the federated server.

Abstract: Systems, devices, and methods for software development or modification. The disclosed technology relates to transforming interactions with physical blocks by a human developer on an activity surface into computer-understandable digital information or logic for developing or modifying software (e.g., websites or mobile applications) in real-time or near real-time. The physical blocks are representative of software elements used in software development. For example, the structures, colors, shapes or hardness/softness/squeeze/bend/flex/elastic/shape-memory/rigid properties, whether symmetrical or asymmetrical, whether open-shaped or close-shaped of the physical blocks can determine which software elements are being developed and the arrangement of the blocks can be mapped to how the software elements are to be included in the software. Users located remotely from the developer can provide annotations or feedback to the software being developed in real-time.

Abstract: An interface between an existing local file system and a data store generates and exports to the data store a versioned file system. The state of the local file system at a given point in time can be determined using the versioned file system. In operation, the interface creates and exports to the data store structured data representations, which correspond to versions of the local file system, as well as actual file system data that these structured data representations represent. A cache associated with the interface stores recently used data and metadata, as well as all write data and metadata waiting to be transferred to the data store. Prior to transfer, one or more data transformations may be applied to the data and metadata. In one embodiment, the data store comprises one or more cloud storage service providers. A content control system is used to configure and manage the interface.

Abstract: Aspects of the disclosure are directed to reducing clock-ungating induced voltage droop by determining a maximum frequency value associated with an output clock waveform; modulating a clock frequency of the output clock waveform for a first time duration based on a first programmable mask pattern or a first Boolean function; and determining if either the first programmable mask pattern or the first Boolean function should be changed. In accordance with one aspect, a voltage droop mitigation circuit includes a control logic for receiving an input clock waveform and a clock enable signal waveform and for outputting a gated clock enable signal waveform; a latch coupled to the control logic, the latch for holding a state of the gated clock enable signal waveform and a AND gate coupled to the latch, the AND gate for outputting an output clock waveform.

Abstract: Systems, devices, and methods for software development or modification. The disclosed technology relates to transforming interactions with physical blocks by a human developer on an activity surface into computer-understandable digital information or logic for developing or modifying software (e.g., websites or mobile applications) in real-time or near real-time. The physical blocks are representative of software elements used in software development. For example, the structures, colors, shapes or hardness/softness/squeeze/bend/flex/elastic/shape-memory/rigid properties, whether symmetrical or asymmetrical, whether open-shaped or close-shaped of the physical blocks can determine which software elements are being developed and the arrangement of the blocks can be mapped to how the software elements are to be included in the software. Users located remotely from the developer can provide annotations or feedback to the software being developed in real-time.

Abstract: A cloud-native global file system, in which one or more filers are associated with a volume of a versioned files system in a private, public or hybrid cloud object store, is augmented to include a rapid ransomware recovery service. Upon detecting a ransomware attack associated with one or more files or directories of the volume, read and write access to the volume is restricted. A recovery filer is then activated or designated in the cloud. A restore operation is then initiated at the recovery filter. Following completion of the restore operation, a new clean (healthy) snapshot of the volume is then created using the recovery filer For any filer other than the recovery filer, a determination is made whether the filer has completed a merge operation with respect to the new clean snapshot. If so, read and write access to the volume is re-enabled from that filer.

Abstract: The present disclosure relates to, inter alia, variants of the receptor binding domain of a coronavirus (e.g., SARS-CoV-2) having increased immunogenicity and reduced aggregation, and the use of the RBD variants in methods for preventing infection of the coronavirus.

Abstract: An interface between an existing local file system and a data store generates and exports to the data store a versioned file system. The state of the local file system at a given point in time can be determined using the versioned file system. In operation, the interface creates and exports to the data store structured data representations, which correspond to versions of the local file system, as well as actual file system data that these structured data representations represent. A cache associated with the interface stores recently used data and metadata, as well as all write data and metadata waiting to be transferred to the data store. Prior to transfer, one or more data transformations may be applied to the data and metadata. In one embodiment, the data store comprises one or more cloud storage service providers. A content control system is used to configure and manage the interface.

Abstract: A technique for data sharing among multiple filers that share a volume in a private or public cloud object store is implemented. In this approach, a mechanism is provided to enable a local filer to determine whether other filers that are sharing the volume have a consistent view of new data being written to the cloud object store by the local filer. The begins by associating together a collection of one or more files in a “push class.” On demand, a push operation for the push class is initiated on the local filer. Preferably, the push is managed according to one or more push criteria associated with the push class. Typically, the push operation pushes file data and metadata associated with the one or more files of the push class in respective phases, with the file data being pushed to the cloud during a first phase and the metadata associated with that file data being pushed during a second phase that follows the first phase.

Abstract: The technology disclosed relates to a system and method for assigning participants to groups in a clinical trial. The system includes a federated server configured with group assignability data specifying a plurality of groups assignable to participants in a clinical trial and group distribution data specifying distribution of the participants into groups. The groups include at least one placebo group and one or more treatment groups. The system includes an intervention server configured to generate group encryption keys for encrypting the group assignability data. The system includes edge devices of each of the participants. The edge devices are in communication with the federated server.

Abstract: An orthodontic bracket and archform system that uses friction-free mechanics are disclosed. The archform can have a male fastener that can be retained within an orthodontic bracket. The orthodontic bracket can have varying locking mechanism, such as deflectable tabs, springs, locking pins, and others, that can cooperate with features of the male fastener to prevent sliding between the archform and the bracket.

Abstract: The technology disclosed provides systems and methods related to preventing exfiltration of training data by feature reconstruction attacks on model instances trained on the training data during a training job. The system comprises a privacy interface that presents a plurality of modulators for a plurality of training parameters. The modulators are configured to respond to selection commands via the privacy interface to trigger procedural calls. The procedural calls modify corresponding training parameters in the plurality of training parameters for respective training cycles in the training job. The system comprises a trainer configured to execute the training cycles in dependence on the modified training parameters. The trainer can determine a performance accuracy of the model instances for each of the executed training cycles.

Abstract: An accessory device for an endoscope includes a cap attached to a shaft of the endoscope, the cap extending along a first axis, a first tip coupled to the cap and movable relative to the cap between a deployed configuration and a non-deployed configuration, and a first shaft defining a lumen and extending proximally from the first tip. In the deployed configuration, the first tip extends along a second axis that is offset from the first axis, and in the non-deployed configuration, the first tip extends along a third axis that is offset from the first axis.