Abstract: A compound according to formula (I) wherein R1 is hydrogen, cyclopropyl, or pyrazolyl, wherein said pyrazolyl is optionally substituted by one or two methyl groups; or a pharmaceutically acceptable salt thereof.

Abstract: A compound of formula (I): wherein R is H or F; or a salt thereof.

Abstract: Disclosed are compounds having the formula (I): wherein R1, R2, and R3 are as defined herein, and methods of making and using the same.

Abstract: A compound of formula (I): which is 4-(3-fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)-3-(3-(2-methoxyethoxy)phenyl)butanoic acid, or a salt thereof.

Abstract: An image analysis system and method determines whether a channel is active by intercepting signals from a set-top box and determining whether the signals correspond to an inactive channel by analyzing pixels, recognized text and/or audio in the signal stream. The system and method controls tuning of the set-top box to each channel to be tested. Data relating to the analysis may be stored and transmitted for processing credit requests.

Abstract: A compound of formula (I): wherein R is H or F; or a salt thereof.

Abstract: A compound according to formula (I) wherein R1 is hydrogen, cyclopropyl, or pyrazolyl, wherein said pyrazolyl is optionally substituted by one or two methyl groups; or a pharmaceutically acceptable salt thereof.

Abstract: A compound of formula (I): which is 4-(3-fluoro-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)-3-(3-(2-methoxyethoxy)phenyl)butanoic acid, or a salt thereof.

Abstract: A compound of formula (I) or a salt thereof: wherein R1 represents a five-membered aromatic heterocycle selected from a N- or a C-linked mono- or di-substituted pyrazole, an N- or a C-linked optionally mono- or di-substituted triazole or an N- or a C-linked optionally mono- or di-substituted imidazole, which five-membered aromatic heterocycle may be substituted by one or two of the groups selected a methyl group, an ethyl group, a fluorine atom, a hydroxymethyl group, a 2-hydroxypropan-2-yl group, a trifluoromethyl group, a difluoromethyl group or a fluoromethyl group, except that when R1 represents an N-linked mono- or di-substituted pyrazole, Ri does not represent 3,5-Dimethyl-1H-pyrazol-1-yl, 5-Methyl-1H-pyrazol-1-yl, 5-Ethyl-3-methyl-1H-pyrazol-1-yl, 3,5-Diethyl-1H-pyrazol-1-yl, 4-Fluoro-3,5-dimethyl-1H-pyrazol-1-yl, 3-Methyl-1H-pyrazol-1-yl or 1H-pyrazol-1-yl.

Abstract: A method for production of a biodiesel is described herein. The method for production of a biodiesel comprises (a) separating solids from a waste oil composition to provide a clarified oil composition; (b) acidifying the clarified oil composition to produce an acidified oil composition including free fatty acids derived from the waste oil; (c) converting at least a portion of the free fatty acids in the acidified oil composition to glycerides to provide a glyceride composition; and (d) reacting at least a portion of the glycerides in the glyceride composition with methanol to form fatty acid methyl ester to provide a biodiesel composition.

Abstract: Embodiments are directed towards push signaling to run jobs on available servers. Users may provide jobs or job instructions to a job control node. Job control node may determine one or more available job target nodes from among a plurality of managed nodes associated with the job control node. The job target nodes may be determined based on information included in the provided job instructions. If there are available job target nodes, the job control node may provide the job instructions to each available job target node. Further, the job control node may receive communications from one or more available job target nodes that indicates that the job target node is prepared and ready to execute the received job instructions. Next, the job control node may issue a job start command that triggers the prepared job target nodes to begin executing the provided job instructions.

Abstract: An engine is described having a crankcase, a liner and a head assembly. The crankcase is split along a plane defining a two part crankcase, where fluid passages are passing through only one of the crankcase portions, so as to not require crossing the split line. A connecting rod also includes a tapered end, and the piston has a complementary carrier receiving the connecting rod.

Abstract: Embodiments generally relate to an alignment device to assist in drilling or reaming an opening in a structure. The device comprises: a base element, the base element having at least one first fixation element to allow fixation of the device relative to the structure; a positioning element coupled to the base element, wherein a position of the positioning element relative to the base element is adjustable; an alignment element mounted to the positioning element and rotatable in at least two dimensions to allow precise alignment for a drilling or reaming tool with a drilling or reaming site on the structure; at least one second fixation element to allow fixation of the positioning element relative to the base element; and at least one third fixation element to allow fixation of the alignment element relative to the positioning element.