Abstract: A system for encouraging a child to learn to read, comprising a computing device and at least one physical manipulative, wherein the computing device can identify the physical manipulative and display at least one word relating to the physical manipulative. In an embodiment, a letter identification board with letter manipulatives is included, wherein a child can spell out a word on the letter identification board and the computing device shows an animation of the physical manipulative performing the action indicated by the word.

Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering PYY or an agonist thereof and GLP-1 or an agonist thereof to the subject, simultaneously or sequentially, thereby decreasing the calorie intake of the subject.

Abstract: The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.

Abstract: The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.

Abstract: An app programming environment that enables a smartphone or tablet app to incorporate real toys or objects into the app, by use of a NFC chip located in the toy or object and a database comprising information regarding the toy or object used.

Abstract: The present invention relates to methods for screening human tissue or fluid samples for changes in the expression of genes, in particular CGB2 and CBG1, characteristic of poor prognosis in cancer such as bladder cancer. The methods have application for the screening, diagnosis or monitoring of other common epithelial cancers including those of the bladder, breast, cervix, colon, endometrium, kidney, lung (including small cell lung carcinoma—SCLC), nasal/pharynx, oro/facial, ovary, prostate, pancreas, vagina and vulva. Methods of treating cancers by reducing the level of expression of CGB2 and CGB1 or products thereof are also disclosed.

Abstract: The expression of a mRNA encoding a putative 76 amino acid, secreted protein (“Enho1”) was found to negatively correlate with fasting triglyceride and cholesterol levels. A recombinant adenovirus was used to increase the expression of Enho1 mRNA in two mouse models of obesity, KK-Ay and Lepob/Lepob mice. Over-expression of Enho1 by adenovirus injection significantly, and reproducibly, reduced fasting triglyceride and cholesterol levels in both models. In addition, transgenic mice strains were made that over express Enho1 protein. Additionally, the expression of a key gene involved in lipogenesis (fatty acid synthase) and FAS protein levels were reduced by ENHO1 adenoviral treatment in Lepob/Lepob mice.

Abstract: The present invention relates to a method for screening maternal urine samples for changes in the pattern of mass spectral fingerprinting which have been found to be characteristic of fetal aneuploidies such as Down's Syndrome and have application for the screening of other fetal abnormalities and disorders of pregnancy including gestational trophoblastic diseases.

Abstract: A set of letter manipulatives and a board on which said letter manipulatives may be placed, where the board comprises an identification module that can identify the letter manipulatives placed on the board and communicate the identification to a computing device.

Abstract: The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.

Abstract: A phonics learning system, comprising a letter identification board and letter manipulatives that may be placed on the letter identification board by a child, and a computing device connected to the letter identification board that identifies the letters placed on the board, generates a phonetic pronunciation for the combination of letters, and identifies any words or misspelled words.

Abstract: A programmable, user-controllable heat storage system and method to provide instant hot water on demand at the desired time while avoiding the waste of energy resulting from continuous pre-heating.

Abstract: An adaptable Internet-connected multimedia display that displays photo or video streams from services such as Instagram or Facebook Photos, and that customizes the photo or video streams depending on environmental factors in its external environment.

Abstract: A method for generating and using a video-based icon (videcon) in a message, where a videcon comprises a (preferably short) video and an associated code, comprising identifying the code within a message, retrieving the video associated with the code, inserting either the video or a link to the video into the message, and sending the message to its intended recipient.

Abstract: The present invention relates to peptide ligands of the melanocortin receptors, in particular the melanocortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.

Abstract: Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering PYY or an agonist thereof and GLP-1 or an agonist thereof to the subject, simultaneously or sequentially, thereby decreasing the calorie intake of the subject.

Abstract: An intelligent, cloud-connected heater/chiller device for water that uses a heat pump to provide heated or chilled water, is programmable by the user to set the temperature levels of the water and the desired usage times, and can also provide carbonated and filtered water.

Abstract: A device and method for displaying and monetizing photo and video images shared on social media services, comprising a display means and a user interface that enables the user to display photo streams from social media services such as Facebook or Instagram, “like” photos shown on the screen, and purchase items or services associated with the photo or video being displayed. The device preferably offers a simple hardware button for “liking” a photo.

Abstract: A triac circuit comprises a triac having first and second main terminals (MT1,MT2) and a gate terminal and a thyristor connected between one of the main terminals (MT1,MT2) and a control terminal of the triac circuit. The thyristor is used to prevent turn on of the triac when it has turned on by temperature induced leakage currents.

Abstract: The expression of a mRNA encoding a putative 76 amino acid, secreted protein (“Enho1”) was found to negatively correlate with fasting triglyceride and cholesterol levels. A recombinant adenovirus was used to increase the expression of Enho1 mRNA in two mouse models of obesity, KK-Ay and Lepob/Lepob mice. Over-expression of Enho1 by adenovirus injection significantly, and reproducibly, reduced fasting triglyceride and cholesterol levels in both models. In addition, transgenic mice strains were made that over express Enho1 protein. Additionally, the expression of a key gene involved in lipogenesis (fatty acid synthase) and FAS protein levels were reduced by ENHO1 adenoviral treatment in Lepob/Lepob mice.