Abstract: Templated document stream integration of checklist data includes loading different checklist templates for a generic endpoint in a computing infrastructure, each containing partially filed data and each corresponding to a different security policy hardening the generic endpoint from a cyberthreat. Specific endpoints are then selected in the computing infrastructure and, for each corresponding specific endpoint, a set of checklists generated, each checklist in the set deriving from a different checklist template and including the partially filled data of one of the different checklist templates. Further, remediation data stored in a data store of an enterprise application is merged into each one of the generated checklists in the set. Finally, the enterprise application is updated with respect to the corresponding one of the selected specific endpoints with the different checklists merging the partially filled data and the remediation data.

Abstract: The present invention relates to methods and means for producing nitrogenase polypeptides in the mitochondria of plant cells.

Abstract: A method of manufacturing a pressure vessel (10) comprising the steps of dividing a wall (104) of a section (100) of the pressure vessel (10) into a first segment (120) and a second segment (150), separating the first segment (120) from the second segment (150), fitting apparatus (400) onto the first segment (120), and then re-attaching the first segment (120) and the second segment (150).

Abstract: Methods for nanopore-based protein analysis are provided. The methods address the characterization of a target protein analyte, which has a dimension greater than an internal diameter of the nanopore tunnel, and which is also physically associated with a polymer. The methods further comprise applying an electrical potential to the nanopore system to cause the polymer to interact with the nanopore tunnel. The ion current through the nanopore is measured to provide a current pattern reflective of the structure of the portion of the polymer interacting with the nanopore tunnel. This is used as a metric for characterizing the associated protein that does not pass through the nanopore.

Abstract: A client application is specified by a target tenant and represented in an OAuth provider, along with a corresponding secret. A source tenant consents to permissions to be executed by the client application on a resource of the source tenant. A target service uses the secret to obtain an access token from an authorization server coupled to the source tenant and uses the access token to obtain access, specified by the permissions, to the resource served by a source service acting on behalf of the source tenant.

Abstract: Disclosed herein are system, method, and device embodiments for implementing dynamic codeless logging in an integration platform system. An integration platform may provide a declaratively-configurable asset pre-configured to implement a logging functionality associated with a log point, package the declaratively-configurable asset within an integration application, and receive a selection of the log point associated with the declaratively-configurable asset. In addition, the integration application may generate log information corresponding to the log point based on the selection of the log point and the logging functionality. Further, the integration platform may present the log information within a graphical user interface.

Abstract: Disclosed herein are system, method, and device embodiments for implementing dynamic codeless logging in an integration platform system. An integration platform may provide a declaratively-configurable asset pre-configured to implement a logging functionality associated with a log point, package the declaratively-configurable asset within an integration application, and receive a selection of the log point associated with the declaratively-configurable asset. In addition, the integration application may generate log information corresponding to the log point based on the selection of the log point and the logging functionality. Further, the integration platform may present the log information within a graphical user interface.

Abstract: A drug-polymer conjugate, which is a copolymer of at least one monomer of formula (I): (I) where: X may be the same or different at each occurrence and represents a terminal functional group comprising an alkyne or an azide; Q is independently selected at each occurrence and may be present or absent and when present, represents a linking group; R is selected from the group consisting of linear or branched hydrocarbon, optionally substituted aryl and optionally substituted heteroaryl; D is a releasable drug selected from prostaglandins, ?-blockers and mixtures thereof; L is a linker group group; and at least one co-monomer of Formula III III J represents a linking functional group, n is 2 to 8, preferably 3 to 8; Y comprises a polyether of formula (ORa)m wherein Ra is independently ethylene, propylene and butylene and m is from 1 to 300 (preferably 2 to 300) and the polyether is in chain with one or more groups which are preferably selected from one or more of optionally substituted straight or branched C1 to

Abstract: A vehicle mounted spreader for spreading materials such as sand, salt, or other granular chemicals onto snow and ice covered road surfaces comprises a hopper for containing the material to be spread, a spinner for spreading the material, a conveyor for conveying the material from the hopper to the spinner, a vehicle speed sensor, a load sensor, and a controller programmed with an intended density of material (e.g., pounds per acre) and desired width of coverage; within the controller the vehicle speed sensor measurement and load sensor inputs are processed to generate outputs to control the speed of the conveyor and spinner, to both control the rate of material distribution and the pattern of material distribution to approach the intended density and width.

Abstract: Disclosed herein are system, method, and device embodiments for implementing dynamic codeless logging in an integration platform system. An integration platform may provide a declaratively-configurable asset pre-configured to implement a logging functionality associated with a log point, package the declaratively-configurable asset within an integration application, and receive a selection of the log point associated with the declaratively-configurable asset. In addition, the integration application may generate log information corresponding to the log point based on the selection of the log point and the logging functionality. Further, the integration platform may present the log information within a graphical user interface.

Abstract: A polymer-prostaglandin conjugate comprising: a polymer backbone comprising a plurality of moieties of formula (I): where: T represents a triazole moiety; Q is independently selected at each occurrence and may be present or absent and when present represents a linking group; R is selected from the group consisting of linear or branched hydrocarbon; D is selected from prostaglandins; and L is a group of formula (II) wherein R5 is selected from hydrogen and C1 to C6 alkyl; (R) indicates the end of the group bonded to the R group; and (D) indicates the end of the group attached to the group D.

Abstract: Disclosed herein are system, method, and device embodiments for implementing dynamic codeless logging in an integration platform system. An integration platform may provide a declaratively-configurable asset pre-configured to implement a logging functionality associated with a log point, package the declaratively-configurable asset within an integration application, and receive a selection of the log point associated with the declaratively-configurable asset. In addition, the integration application may generate log information corresponding to the log point based on the selection of the log point and the logging functionality. Further, the integration platform may present the log information within a graphical user interface.

Abstract: Disclosed herein are system, method, and device embodiments for implementing dynamic codeless logging in an integration platform system. An integration platform may provide a declaratively-configurable asset pre-configured to implement a logging functionality associated with a log point, package the declaratively-configurable asset within an integration application, and receive a selection of the log point associated with the declaratively-configurable asset. In addition, the integration application may generate log information corresponding to the log point based on the selection of the log point and the logging functionality. Further, the integration platform may present the log information within a graphical user interface.

Abstract: Techniques are disclosed for aligning fiducial markers that commonly exist in each of multiple different N-dimensional (N-D) data sets. Notably, the N-D data sets are at least three-dimensional (3D) data sets. A first set and a second set of N-D data are accessed. A set of one or more fiducial markers that commonly exist in both those sets are identified. Based on the fiducial markers, one or more transformations are performed to align the two sets. Performing this alignment process results in at least a selected number of the common fiducial markers that exist in the two sets being within a threshold alignment relative to one another.

Abstract: A class of compounds useful in pharmaceutical compositions and methods for treating or preventing cancer is described. Analogs of Mycalolide B have been prepared and tested in breast and ovarian cancer cell lines. The compounds show utility for inhibition of survival and proliferation of tumor cells. The compounds have been shown to disrupt actin.

Abstract: Resolving conflicting changes to structured data files. A method includes for a structured data file which has both a generic structure and dialects built on top of the generic structure, for which conflicting changes have been made, and where an original version of the structured data, a first version of the structured data and a second version of the structured data exist, determining a dialect of the structured data. The method further includes, based on the determined dialect performing at least one of merge or diff operations on the original version of the structured data, the first version of the structured data and the second version of the structured data.

Abstract: Disclosed herein are system, method, and device embodiments for implementing dynamic codeless logging in an integration platform system. An integration platform may provide a declaratively-configurable asset pre-configured to implement a logging functionality associated with a log point, package the declaratively-configurable asset within an integration application, and receive a selection of the log point associated with the declaratively-configurable asset. In addition, the integration application may generate log information corresponding to the log point based on the selection of the log point and the logging functionality. Further, the integration platform may present the log information within a graphical user interface.

Abstract: A drug-polymer conjugate, which is a copolymer of at least one monomer of formula (I) where: X may be the same or different at each occurrence and represents a terminal functional group comprising an alkyne or an azide; Q is independently selected at each occurrence and may be present or absent and when present, represents a linking group; R is selected from the group consisting of linear or branched hydrocarbon, optionally substituted aryl and optionally substituted heteroaryl; D is a releasable bicyclic prostaglandin; L is a linker group; and at least one co-monomer of Formula III J-(Y1-A)n, J represents a linking functional group, n is 2 to 8 preferably 3 to 8; Y1 comprises a polyether of formula (ORa)m wherein Ra is independently ethylene, propylene and butylene and m is from 1 to 300 (preferably 2 to 300) and the polyether is in chain with one or more groups which are preferably selected from one or more of optionally substituted straight or branched C1 to C10 alkylene, amino, ether, ester, amide, carbon

Abstract: Techniques are disclosed for aligning fiducial markers that commonly exist in each of multiple different N-dimensional (N-D) data sets. Notably, the N-D data sets are at least three-dimensional (3D) data sets. A first set and a second set of N-D data are accessed. A set of one or more fiducial markers that commonly exist in both those sets are identified. Based on the fiducial markers, one or more transformations are performed to align the two sets. Performing this alignment process results in at least a selected number of the common fiducial markers that exist in the two sets being within a threshold alignment relative to one another.

Abstract: The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.