Abstract: Disclosed herein are system, method, and computer program product embodiments for providing anomaly feedback monitoring and detection. An embodiment operates by determining a first set of data corresponding to an anomaly indicating an undesirable data state for a first application. A subset of data from a second set of data corresponding to the undesirable data state is identified, wherein the second set of data is associated with communications between the first application and a second application. A notification identifying the anomaly is provided. Feedback associated with the anomaly is received. Data corresponding to the anomaly is updated based on the feedback.

Abstract: Disclosed herein are system, method, and computer program product embodiments for providing clustering and monitoring functionality. An embodiment operates by determining that an application programming interface (API) call has been made from a first application to a second application. Metric data regarding a performance of one or more computing devices responsive to the determined API call is received. The received metric data associated with the determined API call is clustered into one of a plurality of predetermined clusters associated with the performance of the one or more computing devices responsive to one or more previous API calls. A notification indicating a system state of the one or more computing devices is determined based on the clustering, and provided.

Abstract: A polymer-prostaglandin conjugate comprising: a polymer backbone comprising a plurality of moieties of formula (I): where: T represents a triazole moiety; Q is independently selected at each occurrence and may be present or absent and when present represents a linking group; R is selected from the group consisting of linear or branched hydrocarbon; D is selected from prostaglandins; and L is a group of formula (II) wherein R5 is selected from hydrogen and C1 to C6 alkyl; (R) indicates the end of the group bonded to the R group; and (D) indicates the end of the group attached to the group D.

Abstract: A drug-polymer conjugate, which is a copolymer of at least one monomer of formula (I): (I) where: X may be the same or different at each occurrence and represents a terminal functional group comprising an alkyne or an azide; Q is independently selected at each occurrence and may be present or absent and when present, represents a linking group; R is selected from the group consisting of linear or branched hydrocarbon, optionally substituted aryl and optionally substituted heteroaryl; D is a releasable drug selected from prostaglandins, ?-blockers and mixtures thereof; L is a linker group group; and at least one co-monomer of Formula III III J represents a linking functional group, n is 2 to 8, preferably 3 to 8; Y comprises a polyether of formula (ORa)m wherein Ra is independently ethylene, propylene and butylene and m is from 1 to 300 (preferably 2 to 300) and the polyether is in chain with one or more groups which are preferably selected from one or more of optionally substituted straight or branched Ci to

Abstract: A method for determining the presence of a copy number imbalance in genomic DNA of a test sample is provided. The method can separately measure hybridization of a single test sample to a first hybridization array and hybridization of a plurality of reference samples to a plurality of other, respective test arrays. A determination of copy number can be based on the best fit reference array, relative to the test array. The best fit can be determined based on the closest or most similar signal-to-noise ratio of the measured signals.

Abstract: This disclosure describes systems, methods, and computer-readable media related to retargeting online advertisement campaign recommendations for advertisements with multiple items or services. Bids may be based on a combined advertisement creative comprising two or more items or services. Dynamically selecting multiple items at bid time using a retargeting model to determine a potential revenue generation amount associated with an event may increase the probability of a conversion event based on the creative that includes the selected items. In some embodiments, a machine-learned retargeting model may be used to select multiple items to be displayed in an advertisement. The retargeting model may be applied to items that were previously viewed by the consumer and may determine a value for each of the items using factors. A bid may be calculated for each of the selected items using the values determined by the retargeting model.

Abstract: A diving system can include a smart buoyancy assistant to automatically adjusts the amount of air in the buoyancy control device (BCD) to maintain buoyancy control during the descent, level hold, or ascent of a dive. In some instances, the smart buoyancy assistant is automatically activated when the system is submerged to a predetermined activation depth. Additionally, the smart buoyancy assistant can add air to the BCD if the system drops below a predetermined maximum depth. The system can capture data representing dive metrics and sensor data and can report such data to a computing device to further aggregate the data and generate dive models to improve the performance of the system. The computing device can use the aggregated data to perform dive analysis and determine if the system is over or under adjusting the amount of air to improve the dive models.

Abstract: Aquatic structures with adjustable buoyancy constructed in part with a vent valve for a buoyancy control device suitable for divers, where the vent valve may be opened by any combination of over-pressure, manual pressure relief or a powered means, where a force to a valve plug is applied by means of a spring that is constrained to prevent entirely lateral and angular movement but in which movement of the plug in the axis of the seat is unconstrained.

Abstract: Disclosed are systems and methods for generating reminder options that are presented to a user when a user browses to a content item to view the item and then browses away from the item. For example, a user may be presented with one or more content items, such as images, advertisements, etc., on a display of a user device. The content item, when interacted with by the user, results in the user being provided with an additional content item, such as a webpage, associated with the content item. If the user selects a back button, or other navigation control that results in a request being sent to navigate away from the additional content item and back to the previously presented content items, rather than just presenting the same previously presented content items again, a reminder option may be presented allowing the user to indicate whether the user desires to receive a later reminder about the additional content item and/or the object indicated in the additional content item.

Abstract: A method and system of and for releasably securing a personal electronic device to an article of clothing. A method and system of and for releasably securing a personal electronic device to an article of clothing including a holder or holster, and/or carrier for securing an electronics device to a person used during exercise and/or sports, performing manual labor, or other physical activity; and, including a corresponding rail or track system integrated into an article of clothing whereby an anchoring or attachment point may be releasably adjusted for ease of use and preferred placement of the device on the person of and by a user.

Abstract: A motor includes a stator comprising windings configured to be energized, and a rotor electromagnetically coupled to the stator and configured to turn relative thereto when the stator is energized. The motor also includes a motor controller configured to measure a speed at which the rotor turns, and energize said stator to generate a first torque output at the rotor when the measured speed is below a first threshold. The motor controller is also configured to energize the stator to generate a second torque output at the rotor when the measured speed is at least the first threshold, wherein the second torque output is greater than the first torque output.

Abstract: The invention relates to the field of flow cytometry and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided are reagent compositions, comprising at least eight distinct fluorochrome-conjugated antibodies comprising a set of at least there identification antibodies for the identification of a leukocyte population of interest and at least four characterization antibodies for further characterization and/or classification of said leukocyte population. Also provided are kits and methods related to the reagent compositions.

Abstract: A stator assembly includes an annular body extending about a central axis and a first stator tooth extending radially from the annular body. The first stator tooth includes a first tip spaced radially from the annular body. The stator assembly also includes a second stator tooth extending radially from the annular body and spaced circumferentially from the first stator tooth. The second stator tooth includes a second tip spaced radially from the annular body. The stator assembly further includes a stiffener positioned between the first stator tooth and the second stator tooth. The stiffener is configured to resist deformation of the stator assembly.

Abstract: A motor includes a stator comprising windings configured to be energized, and a rotor electromagnetically coupled to the stator and configured to turn relative thereto when the stator is energized. The motor also includes a motor controller configured to measure a speed at which the rotor turns, and energize said stator to generate a first torque output at the rotor when the measured speed is below a first threshold. The motor controller is also configured to energize the stator to generate a second torque output at the rotor when the measured speed is at least the first threshold, wherein the second torque output is greater than the first torque output.

Abstract: A method and system of and for releasably securing a personal electronic device to an article of clothing. A method and system of and for releasably securing a personal electronic device to an article of clothing including a holder or holster, and/or carrier for securing an electronics device to a person used during exercise and/or sports, performing manual labor, or other physical activity; and, including a corresponding rail or track system integrated into an article of clothing whereby an anchoring or attachment point may be releasably adjusted for ease of use and preferred placement of the device on the person of and by a user.

Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety comprising prostaglandin analogues. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.

Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from prostaglandin analogues, .beta.-blockers and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the treatment of glaucoma.

Abstract: The present invention relates in general to polymer-bioactive agent conjugates for delivering a bioactive agent to a subject. The polymer-bioactive agent conjugates contain triazole moieties in the polymer backbone and a bioactive moiety selected from quinolones, NSAIDs and mixtures thereof. The present invention also relates to methods for preparing the polymer conjugates using click cycloaddition chemical reactions, to monomer-bioactive agent conjugates suitable for preparing the polymer conjugates, and to pharmaceutical products comprising the polymer conjugates for the post-surgical care to treat or prevent infections, provide analgesia and treat inflammation.

Abstract: An electric motor assembly includes a rotor assembly configured to rotate about a central axis and a stator assembly configured to extend about the rotor assembly. The rotor assembly includes at least one of the following: a plurality of spokes and at least one neodymium iron boron magnet. The stator assembly includes an annular body including an inner surface and an outer surface. A first thickness is defined between the inner surface and the outer surface. The stator assembly also includes a plurality of stator teeth extending radially from the annular body and spaced circumferentially about the annular body. Each stator tooth has a second thickness. A ratio of the second thickness to the first thickness is in a range of about 0.5 to about 1. The stator assembly includes no more than 24 slots defined by the plurality of stator teeth.

Abstract: A device for the delivery of an agent to an intestinal site has a backing element, a mucoadhesive element for adhering the device to the intestinal site, and a reservoir comprising the agent. The mucoadhesive element includes a polymer, an opposing surface having the capacity to adhere to the intestinal site, and a population of passageway(s) extending from the reservoir to the opposing surface for delivery of the agent from the reservoir to the intestinal site, each of the passageway(s) having a minimum diameter greater than 10 microns, the diameter being determined by cryogenic scanning electron microscopy after 30 minutes of hydration at 20° C. in phosphate buffered saline at pH 6.5.