Patents by Inventor Andrew Kramer

Andrew Kramer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070179546
    Abstract: A pacing system for providing optimal hemodynamic cardiac function for parameters such as ventricular synchrony or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or stroke volume (aortic pulse pressure) using system for calculating atrio-ventricular delays for optimal timing of a ventricular pacing pulse. The system providing an option for near optimal pacing of multiple hemodynamic parameters. The system deriving the proper timing using electrical or mechanical events having a predictable relationship with an optimal ventricular pacing timing signal.
    Type: Application
    Filed: December 7, 2006
    Publication date: August 2, 2007
    Inventors: Yinghong Yu, Jiang Ding, Julio Spinelli, Andrew Kramer
  • Publication number: 20070150014
    Abstract: A cardiac rhythm management (CRM) system includes a non-invasive hemodynamic sensing device and an implantable medical device to sense a hemodynamic signal and derive one or more cardiac performance parameters from the hemodynamic signal. The non-invasive hemodynamic sensing device includes at least a portion configured for external attachment to a body in which the implantable medical device is implanted. The one or more cardiac performance parameters are used for various diagnostic, monitoring, and therapy control purposes.
    Type: Application
    Filed: December 22, 2005
    Publication date: June 28, 2007
    Inventors: Andrew Kramer, Joseph Pastore, Jeffrey Stahmann, Rodney Salo, Jesse Hartley
  • Publication number: 20070137655
    Abstract: Systems and methods are provided for resisting posterior movement of the tongue during sleep, thereby keeping an airway open. The systems and methods employ a first structure that can be placed either in or on a tongue within an oral cavity and/or in a region of hyoid muscle. The first structure includes a ferromagnetic material. The systems and methods employ a second structure that can be placed either in or on external tissue outside the oral cavity and/or in or on external tissue outside the oral cavity in a desired relationship with the first structure. The second structure includes a magnetic material that magnetically interacts with the ferromagnetic material by attracting the ferromagnetic material, thereby resisting posterior movement of the tongue.
    Type: Application
    Filed: November 3, 2006
    Publication date: June 21, 2007
    Inventors: Joe Paraschac, Ryan Boucher, Edward Gillis, Octavian Iancea, Andrew Kramer, Brian McCollum, Scott McGill, Lionel Nelson, Andres Tomas
  • Publication number: 20070142864
    Abstract: According to an embodiment of a method for providing neural stimulation, activity is sensed, and neural stimulation is automatically controlled based on the sensed activity. An embodiment determines periods of rest and periods of exercise using the sensed activity, and applies neural stimulation during rest and withdrawing neural stimulation during exercise. Other embodiments are provided herein.
    Type: Application
    Filed: November 9, 2006
    Publication date: June 21, 2007
    Inventors: Imad Libbus, Andrew Kramer
  • Publication number: 20070142871
    Abstract: Various aspects relate to an implantable device. Various device embodiments comprise at least one pulse generator and a controller to communicate with the pulse generator(s). The pulse generator(s) is (are) adapted to deliver a first electrical signal through at least one electrode positioned proximate to a vagus nerve and to deliver a second electrical signal through at least one electrode positioned within or proximate to the heart. The controller includes a module to provide epilepsy therapy that includes delivering the first electrical signal though the at least one electrode proximate to the vagus nerve and a module to provide a cardiac rhythm management (CRM) therapy that includes delivering the second electrical signal through at least one electrode positioned within or proximate to the heart. The CRM therapy includes at least one therapy selected from an antitachycardia therapy and a cardiac resynchronization therapy (CRT). Other aspects and embodiments are provided herein.
    Type: Application
    Filed: December 20, 2005
    Publication date: June 21, 2007
    Inventors: Imad Libbus, Andrew Kramer
  • Publication number: 20070135854
    Abstract: A pacing system provides for optimal hemodynamic cardiac function for parameters such as ventricular synchrony or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or stroke volume (aortic pulse pressure) using system for calculating atrio-ventricular delays for optimal timing of a ventricular pacing pulse. The system deriving the proper timing using electrical or mechanical events having a predictable relationship with an optimal ventricular pacing timing signal. A look-up table relating the timing of such electrical or mechanical events to atrio-ventricular delay time intervals is provided for programming the pacing system.
    Type: Application
    Filed: February 14, 2007
    Publication date: June 14, 2007
    Inventors: Andrew Kramer, Jiang Ding, Yinghong Yu, Julio Spinelli
  • Publication number: 20070135853
    Abstract: A cardiac rhythm management device which employs pacing therapy to regularize the ventricular rhythm. Such ventricular rate regularization may be employed within bradycardia pacemakers, ventricular resynchronization devices, or implantable cardioverter/defibrillators.
    Type: Application
    Filed: February 9, 2007
    Publication date: June 14, 2007
    Applicant: Cardiac Pacemakers, Inc.
    Inventors: Andrew Kramer, Jeffrey Stahmann
  • Publication number: 20070118179
    Abstract: A device and method for multi chamber pacing a patient's heart having heart failure and intrinsic conduction, wherein ventricular tracking is used to pace the ventricle when the sinus rate exceeds a preset atrial maximum tracking rate. The ventricular tracking pacemaker increases the range of pacing the ventricle. The ventricular tracking minimizes the loss of ventricular pacing caused by intrinsic conduction when the sinus rate is below an atrial maximum tracking rate, and it induces a new ventricular pacing behavior for sinus rates above the atrial maximum tracking rate without any significant pacing hysteresis as the sinus rate returns towards the lower rate limit.
    Type: Application
    Filed: January 18, 2007
    Publication date: May 24, 2007
    Inventors: Andrew Kramer, Albert Maarse, Jeffrey Stahmann, Rene Wentkowski
  • Publication number: 20070073348
    Abstract: A method for operating a cardiac pacemaker in which the mode of operation of the pacemaker is altered in response to detecting an episode of atrial tachycardia. In accordance with the invention, the pacemaker's pacing mode is altered in a manner that attempts to maintain hemodynamic stability during the atrial tachycardia. Such a mode switch is particularly applicable to pacemaker patients suffering from some degree of congestive heart failure.
    Type: Application
    Filed: October 13, 2006
    Publication date: March 29, 2007
    Inventors: Jeffrey Stahmann, Andrew Kramer
  • Publication number: 20070054871
    Abstract: A gene regulatory system detects ischemia events and is capable of delivering a biologic therapy in response to the detection of an ischemic event or the reception of a command. The biologic therapy protects the heart from ischemic damage by regulating the expression of an exogenously introduced gene product. In one embodiment, the gene regulatory system includes an implantable system that emits at least one gene regulatory signal in response to the detection of the ischemic event or the reception of the command. The gene regulatory signal directly or indirectly regulates gene expression of the gene product.
    Type: Application
    Filed: September 6, 2005
    Publication date: March 8, 2007
    Inventors: Joseph Pastore, Jeffrey Ross, Tamara Baynham, Rodney Salo, Andrew Kramer, Julio Spinelli
  • Publication number: 20070055317
    Abstract: A method and device for delivering pre-excitation pacing to prevent or reduce cardiac remodeling following a myocardial infarction is described. The pre-excitation pacing is modulated in accordance with an intravascular pressure measurement in order to balance the beneficial effects of stress reduction with hemodynamic compromise.
    Type: Application
    Filed: September 6, 2005
    Publication date: March 8, 2007
    Inventors: Jeffrey Stahmann, Joseph Pastore, Andrew Kramer, Rodney Salo, Jesse Hartley
  • Publication number: 20070043396
    Abstract: A system and method recording sensing and pacing events in a cardiac rhythm management device. The method may be particularly useful in assessment of pacing parameters for ventricular resynchronization therapy.
    Type: Application
    Filed: October 30, 2006
    Publication date: February 22, 2007
    Inventors: Jeffrey Stahmann, Rene Wentkowski, Andrew Kramer, James Kalgren
  • Publication number: 20070016260
    Abstract: A device and method for improving tachyarrhythmia detection when the ventricles are resynchronized by delivering paces to both ventricles separated by a specified offset interval. Timing of escape intervals and tachyarrhythmia detection is based upon senses from one of the ventricles designated as a rate ventricle. A reversion pacing mode is provided in order to prevent tachyarrhythmia detection from being compromised when the rate ventricle is paced after the other ventricle.
    Type: Application
    Filed: September 18, 2006
    Publication date: January 18, 2007
    Inventors: Kenneth Baker, David Perschbacher, Andrew Kramer, Jeffrey Stahmann
  • Publication number: 20060293714
    Abstract: Devices and methods for therapy control based on electromechanical timing involve detecting electrical activation of a patient's heart, and detecting mechanical cardiac activity resulting from the electrical activation. A timing relationship is determined between the electrical activation and the mechanical activity. A therapy is controlled based on the timing relationship. The therapy may improve intraventricular dyssynchrony of the patient's heart, or treat at least one of diastolic and systolic dysfunction and/or dyssynchrony of the patient's heart, for example. Electrical activation may be detected by sensing delivery of an electrical stimulation pulse to the heart or sensing intrinsic depolarization of the patient's heart. Mechanical activity may be detected by sensing heart sounds, a change in one or more of left ventricular impedance, ventricular pressure, right ventricular pressure, left atrial pressure, right atrial pressure, systemic arterial pressure and pulmonary artery pressure.
    Type: Application
    Filed: June 28, 2005
    Publication date: December 28, 2006
    Inventors: Rodney Salo, Joseph Pastore, Andrew Kramer, Jeffrey Stahmann, Jesse Hartley
  • Publication number: 20060293716
    Abstract: An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
    Type: Application
    Filed: September 1, 2006
    Publication date: December 28, 2006
    Inventors: Andrew Kramer, Rodney Salo, Julio Spinelli, Bruce KenKnight
  • Publication number: 20060287683
    Abstract: A method and device for delivering pre-excitation pacing to prevent or reduce cardiac remodeling following a myocardial infarction is described. The pre-excitation pacing is modulated in accordance with an assessment of cardiac function in order to balance the beneficial effects of stress reduction with hemodynamic compromise.
    Type: Application
    Filed: March 13, 2006
    Publication date: December 21, 2006
    Inventors: Joseph Pastore, Rodney Salo, Jesse Hartley, Andrew Kramer, Jeffrey Stahmann
  • Publication number: 20060276847
    Abstract: A pacing system for providing optimal hemodynamic cardiac function for parameters such as ventricular synchorny or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or stroke volume (aortic pulse pressure) using system for calculating atrio-ventricular delays for optimal timing of a ventricular pacing pulse. The system providing an option for near optimal pacing of multiple hemodynamic parameters. The system deriving the proper timing using electrical or mechanical events having a predictable relationship with an optimal ventricular pacing timing signal.
    Type: Application
    Filed: August 8, 2006
    Publication date: December 7, 2006
    Inventors: Yinghong Yu, Jiang Ding, Julio Spinelli, Andrew Kramer
  • Publication number: 20060271108
    Abstract: A neural stimulation system includes a safety control system that prevents delivery of neural stimulation pulses from causing potentially harmful effects. The neural stimulation pulses are delivered to one or more nerves to control the physiological functions regulated by the one or more nerves. Examples of such harmful effects include unintended effects in physiological functions associated with autonomic neural stimulation and nerve injuries caused by excessive delivery of the neural stimulation pulses.
    Type: Application
    Filed: May 24, 2005
    Publication date: November 30, 2006
    Inventors: Imad Libbus, Andrew Kramer, William Linder, Jeffrey Stahmann
  • Publication number: 20060271118
    Abstract: Various aspects of the present subject matter relate to an implantable device. Various device embodiments comprise at least one port to connect to at least one lead with at least electrode, stimulation circuitry connected to the at least one port and adapted to provide at least one neural stimulation therapy to at least one neural stimulation target using the at least one electrode, sensing circuitry connected to the at least one port and adapted to provide a sensed signal, and a controller connected to the stimulation circuitry to provide the at least one neural stimulation therapy and to the sensing circuitry to receive the sensed signal. In response to a triggering event, the controller is adapted to switch between at least two modes. Other aspects and embodiments are provided herein.
    Type: Application
    Filed: May 25, 2005
    Publication date: November 30, 2006
    Inventors: Imad Libbus, Andrew Kramer, William Linder, Jeffrey Stahmann
  • Publication number: 20060259088
    Abstract: An implantable cardiac protection pacing system delivers pacing pulses to protect the heart from injuries associated with ischemia and myocardial infarction. The system includes an implantable pulse generator (PG) that delivers the pacing pulses and a coronary stent electrically connected to the implantable PG to function as a pacing electrode through which the pacing pulses are delivered. In one embodiment, an intravascular lead provides the electrical connection between the coronary stent and the implantable PG to allow the implantable PG to be implanted in the femoral region. In another embodiment, the coronary stent and the implantable PG are integrated into an intravascular pulse generator-stent.
    Type: Application
    Filed: May 13, 2005
    Publication date: November 16, 2006
    Inventors: Joseph Pastore, Andrew Kramer, Julio Spinelli, Rodney Salo, Tamara Baynham, Jeffrey Ross, Frits Prinzen, Ward Vanagt, Richard Cornelussen