Abstract: Safety pacing in multi-site cardiac rhythm management (CRM) devices is provided. According to various method embodiments, a first cardiac signal from a first cardiac region and a second cardiac signal from a second cardiac region are sensed. The first cardiac region is paced to maintain at least a minimum cardiac rate, and the second cardiac region is paced to maintain at least the minimum cardiac rate when a pace in the first cardiac region is inhibited. Other aspects and embodiments are provided herein.

Abstract: Carboxyalkylcellulose esters are disclosed having relatively low degrees of polymerization. These new carboxyalkylcellulose esters include carboxymethylcellulose acetate, carboxymethylcellulose acetate propionate, and carboxymethylcellulose acetate butyrate. The inventive esters exhibit solubility in a range of organic solvents, and are useful in coatings and ink compositions as binder resins and rheology modifiers.

Abstract: The present invention relates to identifying and using groups of cardiac events associated with depolarization wavefronts to coordinate the delivery of pacing therapy to the heart. According to one aspect of the invention, cardiac events associated with a plurality of cardiac sites are detected. The cardiac sites may be located in a single heart chamber or in bilateral heart chambers. A group of detected cardiac events associated with a depolarization wavefront is identified. According to another aspect of the invention, a particular cardiac event of an identified group associated with a depolarization wavefront may be used to synchronize pacing therapy delivered to the heart. According to yet another aspect, premature ventricular contractions may be classified using the identified groups.