Abstract: The disclosed computer-implemented method may include (1) receiving, via a social networking system, a request from a user to participate in a discovery service designed to facilitate connections between users of the social networking system who share common attributes, (2) obtaining, from the user, data representative of at least one desired user attribute, possessed by the user, for new user connections, (3) identifying, within the social networking system, at least one additional user who is both a participant in the discovery service and who also possesses the desired user attribute, and (4) providing a visual indication to the user, when representing the additional user within a user interface of the social networking system, that the additional user is a participant in the discovery service and that the additional user possesses the desired user attribute. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of kinase activity, in particular PI3-kinase activity.

Abstract: A disclosed computer-implemented method may include determining that a user of a social networking system is (1) a participant in a dating service of the social networking system, and (2) a member of an interest-based community of the social networking system that includes an activated community-based dating feature. The method may further include receiving a request from the user for access to the community-based dating feature, and providing, in response to receiving the request, the user with access to the community-based dating feature by (1) identifying at least one additional member of the interest-based community who is an additional participant in the dating service, and (2) presenting dating information associated with the additional member of the interest-based community within a dating interface of the social networking system. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Systems, methods, and non-transitory computer readable media are configured to provide a first element in an interface presentable to a user through which a plurality of ephemeral media content items are accessible by the user for a selected period of time. A second element in the interface through which a plurality of non-ephemeral media content items are accessible by the user is provided.

Abstract: The present invention relates to novel aminoindazolyl derivative compounds of Formula (I), the use of said compounds in treating diseases mediated by modulation of voltage-gated sodium channels in particular Nav1.7 AND to compositions containing said derivatives.

Abstract: An infrared detector useful in, e.g., infrared cameras, includes a substrate having an array of infrared detectors and a readout integrated circuit interconnected with the array disposed on an upper surface thereof, for one or more embodiments. A generally planar window is spaced above the array, the window being substantially transparent to infrared light. A mesa is bonded to the window. The mesa has closed marginal side walls disposed between an outer periphery of a lower surface of the window and an outer periphery of the upper surface of the substrate and defines a closed cavity between the window and the array that encloses the array. A solder seal bonds the mesa to the substrate so as to seal the cavity.

Abstract: Methods and apparatus for performing knee arthroplasty, including, but not limited to, bicruciate retaining knee arthroplasty, ore described herein. Methods and apparatus for preparing a distal femur for a femoral implant as well as methods and apparatus for preparing a proximal tibia for a tibial implant are described. These methods and apparatus, in at least some embodiments and uses, facilitate decreasing the complexity of knee arthroplasty procedures such as bicruciate retaining procedures, while maintaining, if not improving on, the safety, accuracy and/or effectiveness of such procedures.

Abstract: The present invention is related to amino thiazole derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).

Abstract: Methods and apparatus for performing knee arthroplasty, including, but not limited to, bicruciate retaining knee arthroplasty, are described herein. Methods and apparatus for preparing a distal femur for a femoral implant as well as methods and apparatus for preparing a proximal tibia for a tibial implant are described. These methods and apparatus, in at least some embodiments and uses, facilitate decreasing the complexity of knee arthroplasty procedures such as bicruciate retaining procedures, while maintaining, if not improving on, the safety, accuracy and/or effectiveness of such procedures.

Abstract: A photon detection device and method of fabricating a photon detection device are provided. The photon detection device comprises a first input terminal for receiving a DC input voltage, a second input terminal for receiving an AC input voltage and a bias tee connected to the first and second input terminals and configured to combine the AC and DC input voltages to form a combined voltage on an output of the bias tee. A first single photon detector is connected to the output of the bias tee and configured to receive the combined voltage from the bias tee, register a detection signal based on only a single photon being incident on the first single photon detector and output the detection signal indicative of the detected photon. A first output terminal is connected to an output of the first single photon detector for outputting the detection signal. The photon detection device is formed in a single integrated circuit.

Abstract: A hub and suspension assembly for tow dolly and car hauler trailer with drop-down capability comprises: a suspension tower, a screw, a chuck, a lug member, an upper threaded block, a spring, a lower non-threaded block, an axle, and a hub. The tow dolly comprises: a plurality of frame members, a first and a second hub and suspension assembly for tow dolly and car hauler trailer with drop-down capability, and a first and a second wheel and tire assembly. Car hauler trailer comprises: a plurality of frame members; a first, second, third, and fourth hub and suspension assembly for a tow dolly and a car hauler trailer with drop-down capability; and a first, second, third, and fourth wheel and tire assembly.

Abstract: A ball-and-socket joint module (26) affixed to a mirror head (14) provides for adjusting a position of a mirror (16). The module includes a multicomponent ball assembly (86) that has an internally mounted spring (82). The spring presses two components (34, 72) of the ball assembly away from each other so that opposing surfaces (32, 70) of the ball assembly confront corresponding surfaces (62, 64) of a multicomponent socket assembly (90) when the ball assembly is nested within the socket assembly.

Abstract: Methods and apparatus for performing knee arthroplasty, including, but not limited to, bicruciate retaining knee arthroplasty, are described herein. Methods and apparatus for preparing a distal femur for a femoral implant as well as methods and apparatus for preparing a proximal tibia for a tibial implant are described. These methods and apparatus, in at least some embodiments and uses, facilitate decreasing the complexity of knee arthroplasty procedures such as bicruciate retaining procedures, while maintaining, if not improving on, the safety, accuracy and/or effectiveness of such procedures.

Abstract: Cyclic ether pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein R2 is a cyclic ether and X is thiazolyl, pyrazinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

Abstract: Hub and suspension assembly for tow dolly and car hauler trailer with drop-down capability comprises: a suspension tower, a screw, a chuck, a lug member, an upper threaded block, a spring, a lower non-threaded block, an axle, and a hub. Tow dolly comprises: a plurality of frame members, a first and second hub and suspension assembly for tow dolly and car hauler trailer with drop-down capability, and a first and second wheel and tire assembly. Car hauler trailer comprises: a plurality of frame members; a first, second, third, and fourth hub and suspension assembly for tow dolly and car hauler trailer with drop-down capability; and a first, second, third, and fourth wheel and tire assembly.

Abstract: Systems, methods, and non-transitory computer readable media are configured to provide a first element in an interface presentable to a user through which a plurality of ephemeral media content items are accessible by the user for a selected period of time. A second element in the interface through which a plurality of non-ephemeral media content items are accessible by the user is provided.

Abstract: Systems, methods, and non-transitory computer readable media are configured to provide a first element in an interface presentable to a user through which a plurality of ephemeral media content items are accessible by the user for a selected period of time. A second element in the interface through which a plurality of non-ephemeral media content items are accessible by the user is provided.

Abstract: Systems, methods, and non-transitory computer readable media are configured to provide a first element in an interface presentable to a user through which a plurality of ephemeral media content items are accessible by the user for a selected period of time. A second element in the interface through which a plurality of non-ephemeral media content items are accessible by the user is provided.