Patents by Inventor Andrew Steven
Andrew Steven has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240156070Abstract: A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline. Methods for making bispecific antibodies having universal light chains using mice as described herein, including human light chain variable regions, are provided. Methods for making human variable regions suitable for use in multispecific binding proteins, e.g., bispecific antibodies, and host cells are provided. Bispecific antibodies capable of binding first and second antigens are provided, wherein the first and second antigens are separate epitopes of a single protein or separate epitopes on two different proteins are provided.Type: ApplicationFiled: August 23, 2023Publication date: May 16, 2024Inventors: Robert Babb, John McWhirter, Lynn Macdonald, Sean Stevens, Samuel Davis, David R. Buckler, Karolina A. Meagher, Andrew J. Murphy, Natasha Levenkova
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Publication number: 20240160109Abstract: Degradation of the reflectivity of one or more reflective optical elements in a system for generating EUV radiation is reduced by the controlled introduction of a gas into a vacuum chamber containing the optical element. The gas may be added to the flow of another gas such as hydrogen or alternated with the introduction of hydrogen radicals.Type: ApplicationFiled: November 14, 2023Publication date: May 16, 2024Inventors: Yue Ma, Antonius Theodorus Wilhelmus Kempen, Klaus Martin Hummler, Johannes Hubertus Josephina Moors, Jeroen Hubert Rommers, Hubertus Johannes Van De Wiel, Andrew David Laforge, Fernando Brizuela, Rob Carlo Wieggers, Umesh Prasad Gomes, Elena Nedanovska, Celal Korkmaz, Alexander Downn Kim, Rui Miguel Duarte Rodrigues Nunes, Hendrikus Alphonsus Ludovicus Van Dijck, William Peter Van Drent, Peter Gerardus Jonkers, Qiushi Zhu, Parham Yaghoobi, Jan Steven Christiaan Westerlaken, Martinus Hendrikus Antonius Leenders, Alexander Igorevich Ershov, Igor Vladimirovich Fomenkov, Fei Liu, Johannes Henricus Wilhelmus Jacobs, Alexey Sergeevich Kuznetsov
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Publication number: 20240158213Abstract: Automated jackstand systems and methods deploy a jackstand to support a front end of a trailer parked at an automated loading dock. The jackstand prevents collapse of the trailer's landing gear and prevents upending of the trailer during loading and unloading. Advantageously, by deploying the jackstand automatically, presence of personnel in the yard where tractors and trailers are moving is not required.Type: ApplicationFiled: January 22, 2024Publication date: May 16, 2024Inventors: Andrew F. Smith, Martin Edward Sotola, Peter James, Lawrence S. Klein, Matthew Steven Johannes, Jonathan Record, Garold McKinney
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Publication number: 20240161448Abstract: A system and method for performing object recognition using chords is disclosed, A chord is a feature representing the distance between edge pixels and/or the angle of a line segment connected to edge pixels. The object recognition system preferably includes: an edge detector, a plurality of transforms, a chord generator, and a summing circuit. The edge detector is configured to detect a plurality of edge pixels in the acquired image and reference image. Each transform is associated with a scale which is the ratio of an input chord length and an output chord length for associated with the transform. The chord generator is configured to generate a first plurality of chords representing a point in the acquired image, and a second plurality of chords representing a point in the reference image.Type: ApplicationFiled: November 9, 2023Publication date: May 16, 2024Inventor: Andrew Steven Naglestad
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Patent number: 11978213Abstract: Illustrative embodiments are directed to a method and apparatus for evaluating boundary detection in an image. A processed image is received, wherein a detected boundary of an image of an object is identified in the processed image. A Radon transform is applied to the processed image for a plurality of angles to form a processed image histogram corresponding to the detected boundary for each of the plurality of angles. The processed image histogram for each of the plurality of angles and a corresponding ground truth histogram for each of the plurality of angles is normalized to provide a normalized processed image histogram and a normalized ground truth histogram for each of the plurality of angles, wherein the ground truth histogram corresponds to a ground truth boundary of the object for a corresponding angle. An indication of the edges of the normalized processed image histogram for each of the plurality of angles is plotted to form a boundary detection evaluation visualization.Type: GrantFiled: May 18, 2021Date of Patent: May 7, 2024Assignee: National Technology & Engineering Solutions of Sandia, LLCInventors: Andrew C. Wantuch, Kyle Saxberg, Edward Steven Jimenez, Jr., Jaxon Gittinger, Srivathsan Koundinyan
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Patent number: 11972095Abstract: Various embodiments discussed herein enable client applications to be heavily integrated with a voice assistant in order to perform commands associated with voice utterances of users via voice assistant functionality and also seamlessly cause client applications to automatically perform native functions as part of executing the voice utterance. Such heavy integration also allows particular embodiments to support multi-modal input from a user for a single conversational interaction. In this way, client application user interface interactions, such as clicks, touch gestures, or text inputs are executed alternative or in addition to the voice utterances.Type: GrantFiled: October 22, 2021Date of Patent: April 30, 2024Assignee: Microsoft Technology Licensing, LLCInventors: Tudor Buzasu Klein, Viktoriya Taranov, Sergiy Gavrylenko, Jaclyn Carley Knapp, Andrew Paul McGovern, Harris Syed, Chad Steven Estes, Jesse Daniel Eskes Rusak, David Ernesto Heekin Burkett, Allison Anne O'Mahony, Ashok Kuppusamy, Jonathan Reed Harris, Jose Miguel Rady Allende, Diego Hernan Carlomagno, Talon Edward Ireland, Michael Francis Palermiti, II, Richard Leigh Mains, Jayant Krishnamurthy
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Patent number: 11970313Abstract: An insulating container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching devices, in the closed configuration. In some examples, the insulating container further includes a pull handle assembly with a telescopic three-stage arm configuration defined by a stowed configuration, a partially extended configuration, and a fully extended configuration. In other examples, the insulating container further includes a wheel assembly with a pair of wheels mounted with one or two axles, and further including a wheel grommet for absorbing shock and cushioning the axle. In still other examples, the insulating container further includes a drain plug assembly on the rear sidewall adjacent to the bottom portion of the base, the drain plug assembly comprising a main tube that cooperatively engages with an outer tube with a plurality of ratchet teeth that engage one or more ratchet keys on the main tube.Type: GrantFiled: May 12, 2022Date of Patent: April 30, 2024Assignee: YETI Coolers, LLCInventors: Liza Morris, Andrew J. Winterhalter, Robert Secker, Dustin R. Bullock, Elizabeth Ruchte, Ryan Nixon, Derek G. Sullivan, John Loudenslager, John Fritz, Erik Steven Larson, Lance Harrison, Michael Christopher Cieszko
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Publication number: 20240134959Abstract: Disclosed herein is a system and a method of providing access to at least one password protected device (D1-D5) via a password management system (100). The password management system (100) comprises first and second password management servers (200), each comprising a memory for storing an active password and a reserve password. The first and second password management servers (200) communicate the active and reserve passwords via a communication link (220). Either one of the first and second password management servers (200) requests access to the password protected device using the active password stored in the memory, and if the active password does not provide access, requests access using the reserve password.Type: ApplicationFiled: October 23, 2023Publication date: April 25, 2024Applicant: Osirium LimitedInventor: Andrew Steven Harris
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Publication number: 20240131286Abstract: A cuffed tracheal tube has a shaft (10) with an inner component (30) having an inflation lumen (23) extending along a rib (33) along the outside of the component. The rib (33) terminates a short distance rearwardly of the patient end (14) of the inner component. The inflation lumen (23) is closed by an outer layer (51) applied over the inner component (30) and covering the patient end of the rib. Two closely spaced openings (54) through the rib (33) are spaced in the inflatable region of a silicone sealing cuff (13) secured around the patient end of the shaft.Type: ApplicationFiled: February 21, 2022Publication date: April 25, 2024Applicant: SMITHS MEDICAL INTERNATIONAL LIMITEDInventors: Laura Beth Morton, Ayesha Bint-E-Siddiq, Neil Steven Veasey, Christopher John Woosnam, Andrew Thomas Jeffrey
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Patent number: 11963521Abstract: Non-human animals comprising a human or humanized IL-4 and/or IL-4R? nucleic acid sequence are provided. Non-human animals that comprise a replacement of the endogenous IL-4 gene and/or IL-4R? gene with a human IL-4 gene and/or IL-4R? gene in whole or in part, and methods for making and using the non-human animals, are described. Non-human animals comprising a human or humanized IL-4 gene under control of non-human IL-4 regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4-encoding sequence with human IL-4-encoding sequence at an endogenous non-human IL-4 locus. Non-human animals comprising a human or humanized IL-4R? gene under control of non-human IL-4R? regulatory elements is also provided, including non-human animals that have a replacement of non-human IL-4R?-encoding sequence with human or humanized IL-4R?-encoding sequence at an endogenous non-human C IL-4R? locus.Type: GrantFiled: August 5, 2021Date of Patent: April 23, 2024Assignee: Regeneron Pharmaceuticals, Inc.Inventors: Li-Hsien Wang, Yingzi Xue, Andrew J. Murphy, Sean Stevens
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Patent number: 11950578Abstract: Mice are provided that comprise a reduction or deletion of ADAM6 activity from an endogenous ADAM6 locus, or that lack an endogenous locus encoding a mouse ADAM6 protein, wherein the mice comprise a sequence encoding an ADAM6 or ortholog or homolog or fragment thereof that is functional in a male mouse. In one embodiment, the sequence is an ectopic ADAM6 sequence or a sequence that confers upon a male mouse the ability to generate offspring by mating. Mice and cells with genetically modified immunoglobulin heavy chain loci that comprise an ectopic nucleotide sequence encoding a mouse ADAM6 or functional fragment or homolog or ortholog thereof are also provided.Type: GrantFiled: December 21, 2020Date of Patent: April 9, 2024Assignee: Regeneron Pharmaceuticals, Inc.Inventors: Lynn Macdonald, Sean Stevens, Andrew J. Murphy, Margaret Karow
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Publication number: 20240109564Abstract: A method is provided that can include activating at least two wireless communication channels in parallel, between a first wireless transceiver and a second wireless transceiver. Each of the at least two wireless communication channels can operate at a different radio carrier frequency, and the first wireless transceiver may be part of a first vehicle. The method can also include transmitting, by the first wireless transceiver, common information in parallel on the at least two wireless communication channels to the second wireless transceiver and deactivating the at least two wireless communication channels.Type: ApplicationFiled: December 12, 2023Publication date: April 4, 2024Inventors: Padam Dhoj Swar, Carl L. Haas, Danial Rice, Rebecca W. Dreasher, Adam Hausmann, Matthew Steven Vrba, Edward J. Kuchar, James Lucas, Andrew Ryan Staats, Jerrid D. Chapman, Jeffrey D. Kernwein, Janmejay Tripathy, Stephen Craven, Tania Lindsley, Derek K. Woo, Ann K. Grimm, Scott Sollars, Phillip A. Burgart, James Allen Oswald, Shannon K. Struttmann, Stuart J. Barr, Keith Smith, Francois P. Pretorius, Craig K. Green, Kendrick Gawne, Irwin Morris, Joseph W. Gorman, Srivallidevi Muthusami, Mahesh Babu Natarajan, Jeremiah Dirnberger, Adam Franco
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Publication number: 20240099278Abstract: Genetically modified non-human animals are provided that may be used to model human hematopoietic cell development, function, or disease. The genetically modified non-human animals comprise a nucleic acid encoding human IL-6 operably linked to an IL-6 promoter. In some instances, the genetically modified non-human animal expressing human IL-6 also expresses at least one of human M-CSF, human IL-3, human GM-CSF, human SIRPa or human TPO. In some instances, the genetically modified non-human animal is immunodeficient. In some such instances, the genetically modified non-human animal is engrafted with healthy or diseased human hematopoietic cells. Also provided are methods for using the subject genetically modified non-human animals in modeling human hematopoietic cell development, function, and/or disease, as well as reagents and kits thereof that find use in making the subject genetically modified non-human animals and/or practicing the subject methods.Type: ApplicationFiled: August 21, 2023Publication date: March 28, 2024Inventors: Richard Flavell, Till Strowig, Markus G. Manz, Chiara Borsotti, Madhav Dhodapkar, Andrew J. Murphy, Sean Stevens, George D. Yancopoulos
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Publication number: 20240090540Abstract: The present invention provides new products using mucilaginous seeds as binders.Type: ApplicationFiled: December 10, 2021Publication date: March 21, 2024Inventors: MADIAN OTHMAN ABU-HARDAN, ARISTODIMOS LAZIDIS, RICARDO ANDRES RODRIGUEZ ROSENDE, ANDREW STEVEN WHITEHOUSE
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Patent number: 11931663Abstract: An automated damping system including a damping device arranged and disposed to provide variable resistance to a load. The variable resistance provides resistance values corresponding to a displacement position of the damping device. The system includes a damping profile generator that calculates a damping profile and a sensor is arranged and disposed to measure one or more damping affecting properties. The sensor provides the one or more damping affecting properties to the damping profile generator. The damping profile provides the variable resistance based upon the one or more damping affecting properties of the load.Type: GrantFiled: July 30, 2021Date of Patent: March 19, 2024Assignee: TAIT TOWERS MANUFACTURING, LLCInventors: Matthew Steven Bettinger, Nicholas James Bonsell, Andrew Phillips Mudie, Andrew John Penney, James Fowler Shumway, Jr., McLane Walker Snow
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Patent number: 11926110Abstract: A method for forming a fiber-reinforced thermoplastic control surface includes forming first and second skins from a fiber-reinforced thermoplastic resin. The method further includes overmolding fiber-reinforced thermoplastic features onto the first skin and/or second skin, including stiffener structures, sidewalls, and/or hinges. The method further comprises welding or consolidating the first and second skins together, along with the associated internal features overmolded thereon to form a single-piece, stiffened, fiber-reinforced thermoplastic control surface.Type: GrantFiled: May 17, 2023Date of Patent: March 12, 2024Assignee: ROHR, INC.Inventors: Samantha Landis, Guinevere Berg, Andrew Cai, Johann Steven Schrell
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Patent number: 11926642Abstract: The invention relates to compounds of formula I wherein R1, R2 and - - - - - are as defined herein, pharmaceutical compositions comprising the compounds and methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds and methods of inhibiting or preventing replication of SARS-CoV-2 with the compounds.Type: GrantFiled: July 1, 2021Date of Patent: March 12, 2024Assignee: Pfizer inc.Inventors: Robert Steven Kania, Padmavani Bezawada, Emma Louise Hawking, Rohit Jaini, Samir Kulkarni, Matthew Nathan O'Brien Laramy, Jonathan Richard Lillis, Suman Luthra, Dafydd Rhys Owen, Klimentina Dimitrova Pencheva, Anil Mahadeo Rane, Matthew Forrest Sammons, Bradley Paul Sullivan, Andrew John Thiel, Martyn David Ticehurst, Jamison Bryce Tuttle, Robert Louis Hoffman
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Patent number: D1018880Type: GrantFiled: December 15, 2021Date of Patent: March 19, 2024Assignee: FKA Distributing Co., LLCInventors: Sean Parker, Andrew Steven Juhasz
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Patent number: D1024758Type: GrantFiled: December 22, 2020Date of Patent: April 30, 2024Assignee: WHITE MULE COMPANYInventors: Larry Steven Ritchey, Andrew Patrick Ritchey
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Patent number: D1028272Type: GrantFiled: January 27, 2023Date of Patent: May 21, 2024Assignee: FKA Distributing Co., LLCInventors: Nathan Chun Kit Siu, Andrew Steven Juhasz