Abstract: A vacuum therapy device for treatment of a defect internal of a human or animal body, the device comprising: a suction tube extending from: (i) a proximal portion for coupling to a source of negative pressure outside the body, to (ii) a distal portion for providing suction proximal to the defect when inserted into the body; a porous medium coupled to the distal portion of the suction tube to provide suction to the defect when inserted into the body for treatment thereof; and a constraining sleeve for selective compression of the porous medium, the constraining sleeve having a proximal end and a distal end, wherein the constraining sleeve is movable relative to the porous medium between: an insertion position in which the proximal and distal ends of the sleeve are arranged at the distal portion of the suction tube so that the sleeve at least partially surrounds the porous medium to retain the porous medium in a compressed state during insertion into the body; and a treatment position in which the porous medium

Abstract: A panel for forming part of a partition is disclosed. The partition may, for example, be a roof, a wall or a floor of a building. The panel comprises: a central panel; two support members; and a resiliently compressible portion. The two support members are disposed on opposed sides of the central panel, each of the two support members extending generally perpendicularly to a plane of the central panel. The resiliently compressible portion is arranged between the two support members such that a distance between the two support members can be reduced by compressing the resiliently compressible portion.

Abstract: A method of detecting a defect in a sheet of glass includes: (i) directing a converging beam from a source of illumination onto a surface of the sheet of glass to illuminate the defect; (ii) focussing an image capture device onto a first plane to image the defect in the sheet of glass; (iii) capturing a first image of the defect; (iv) carrying out an adjustment step; and (v) capturing a second image of the defect. Each of the first and second images has a respective first portion from the illuminated defect and a respective second portion due to reflection of a portion of the beam from the glass surface. In the first image of the defect the first portion is brighter than the second portion, and in the second image of the defect the first portion is darker than the second portion. An apparatus for carrying out the method is also provided.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Embodiments facilitate interoperability and secure determination of healthcare costs. An entity may receive a first Electronic Health Record (EHR) sub-block with patient medical coverage information and first treatments and may transmit a first Device Drug Information (DIR) sub-block comprising first treatment classes corresponding to each first treatment, first treatment class members corresponding to each first treatment class, and corresponding first treatment class member cost information. In response, the entity may receive a second EHR sub-block comprising second treatments each: associated with a corresponding first treatment, and selected from corresponding first treatment class members. Upon receipt of a transaction confirmation, the entity may augment a multi-dimensional blockchain with a multi-dimensional block formed by linking: a DIR block including second treatment information, an EHR block including information based on the second EHR sub-block and a transaction block.

Abstract: Embodiments facilitate interoperability and secure patient selection for clinical trials and drug/device deployments. An entity may obtain a first set of health parameters and collective demographic information associated with one or more population segments and receive Electronic Health Record (EHR) sub-blocks with patient profile information and corresponding patient medical histories for patients. The entity may determine a subset of eligible candidate patients for a treatment based on information in the EHR sub-blocks and eligibility criteria for the treatment, which may be based the first set of health parameters, and/or the collective demographic information.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Methods, computer systems, computer-storage media, and graphical user interfaces are provided for facilitating data visualization generation. In one implementation, dataset intent data, visual design intent data, and insight intent data determined from a user input natural language query are obtained. A set of candidate intent recommendations is generated using various combinations of the dataset intent data, visual design intent data, and insight intent data. Each of the candidate intent recommendations is incorporated into a set of visualization templates to determine eligibility of the candidate intent recommendations. For eligible candidate intent recommendations, a score associated with a corresponding visualization template is determined. Based on the scores, a candidate intent recommendation and corresponding visualizations template is selected to use as a visual recommendation for presenting a data visualization.

Abstract: A modular partition system comprises a plurality of panels and at least one connecting strip. Each of the plurality of panels comprises two support members extending generally perpendicularly to a plane of the modular partition system and a central panel extending between said two support panels. The plurality of panels are arranged such that the central panels of each of the plurality of panels are generally mutually parallel and one support member of each of the plurality of panels is adjacent to a support member of an adjacent panel. The at least one connecting strip cooperates with a support member from each of two of the plurality of adjacent panels so as to connect said two of the plurality of adjacent panels.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Methods, systems, and non-transitory computer readable media are disclosed for utilizing machine learning models to extract digital signals from low-results web queries and generate item demand deficiency predictions for digital item lists corresponding to websites. In one or more embodiments, the disclosed systems identify a low-results query submitted by client devices navigating a website. The disclosed systems generate features for the low-results query and the digital item list to generate a deficiency prediction relative to demand indicated by the low-results query. In some embodiments, the disclosed system utilizes a deficiency prediction model to process the extracted signals and generate a deficiency confidence score corresponding to the low-results query. Based on the deficiency confidence score, the disclosed system can generate and provide demand notifications via one or more graphical user interfaces.

Abstract: An electronic construction collaboration system for managing a construction project is provided. The electronic construction collaboration system includes an Enterprise Resource Planning (ERP) sub-system including a contract engine configured to generate at least one project contract including a contract data set and ERP metadata corresponding to Building Information Modeling (BIM) metadata included in a structural object of a construction project model in a BIM sub-system and an interconnection engine configured to associatively link the ERP metadata and the BIM metadata and send the contract data set to the BIM sub-system in response to associatively linking the ERP metadata and the BIM metadata.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: A modular partition system comprises a plurality of panels and at least one connecting strip. Each of the plurality of panels comprises two support members extending generally perpendicularly to a plane of the modular partition system and a central panel extending between said two support panels. The plurality of panels are arranged such that the central panels of each of the plurality of panels are generally mutually parallel and one support member of each of the plurality of panels is adjacent to a support member of an adjacent panel. The at least one connecting strip cooperates with a support member from each of two of the plurality of adjacent panels so as to connect said two of the plurality of adjacent panels.

Abstract: An attachment assembly (25) and a ground engaging assembly for releasable attachment with earthmoving equipment is disclosed. In at least one embodiment, the attachment assembly (25) comprises a first body (30) configured for being placed in affirmative engagement with a portion (32) of or in fixed relation with respect to an edge of or associated with the earthmoving equipment. The attachment assembly (25) comprises a second body (35) configured for being placed in affirmative engagement with a portion of the ground engaging tool (GET, 15C or 15).

Abstract: A tile system comprises at least two tiles and at least one elongate support. Each tile is generally rectangular in shape and has a first edge, and a second edge, the second edge being generally opposite the first edge. Each elongate support has an attachment portion and a support portion. Proximate the first edge each tile is provided with a groove, the groove being configured to receive the support portion of one of the elongate supports and a portion of an adjacent tile proximate its second edge.

Abstract: Embodiments facilitate interoperability and secure determination of healthcare costs. An entity may receive a first Electronic Health Record (EHR) sub-block with patient medical coverage information and first treatments and may transmit a first Device Drug Information (DIR) sub-block comprising first treatment classes corresponding to each first treatment, first treatment class members corresponding to each first treatment class, and corresponding first treatment class member cost information. In response, the entity may receive a second EHR sub-block comprising second treatments each: associated with a corresponding first treatment, and selected from corresponding first treatment class members. Upon receipt of a transaction confirmation, the entity may augment a multi-dimensional blockchain with a multi-dimensional block formed by linking: a DIR block including second treatment information, an EHR block including information based on the second EHR sub-block and a transaction block.

Abstract: Embodiments facilitate interoperability and secure patient selection for clinical trials and drug/device deployments. An entity may obtain a first set of health parameters and collective demographic information associated with one or more population segments and receive Electronic Health Record (EHR) sub-blocks with patient profile information and corresponding patient medical histories for patients. The entity may determine a subset of eligible candidate patients for a treatment based on information in the EHR sub-blocks and eligibility criteria for the treatment, which may be based the first set of health parameters, and/or the collective demographic information.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.