Patents by Inventor Anna W. Topol
Anna W. Topol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11513999Abstract: A system, method and computer program product for archiving image, audio, and text data with metadata encapsulation in a client-server storage library is described. The server receives and holds the images, audio, or text to be archived in an image, audio or text logical partition which includes a directory of the images, audio, or text. The information is encapsulated in a metadata wrapper and stored in the library as a closed image, audio, or text file along with a closed copy of the directory. The closed image, audio, or text directory is also stored in the client. The images may be encapsulated in MXF, DICOM, Tape Archive (TAR) or GZIP formats. The storage library may have magnetic tapes, magnetic disks or optical disks as storage media.Type: GrantFiled: February 27, 2019Date of Patent: November 29, 2022Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Daniel J. Winarski, Yun Mou, Allen K. Bates, Stephen Leonard Schwartz, Craig A. Klein, Louie A. Dickens, Timothy A. Johnson, Anna W. Topol
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Patent number: 11408947Abstract: The inventive concepts presented herein relate to methods of identifying molecules identification of molecules using apparatuses including: electromagnetic write-head(s); magneto-resistive read sensor(s), and processor(s). An exemplary method includes scanning one or more of a plurality of biosample tracks of a biosample substrate using an electromagnetic write-head to magnetically excite one or more molecules of interest using an alternating magnetic field. The one or more molecules of interest are disposed on one or more of the biosample tracks. A resonant response of the one or more molecules of interest is measured using a magneto-resistive sensor. The resonant response is compared to a table of known resonant responses to identify the one or more molecules of interest.Type: GrantFiled: May 28, 2019Date of Patent: August 9, 2022Assignee: International Business Machines CorporationInventors: Allen K. Bates, Anna W. Topol, Daniel J. Winarski
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Patent number: 11067568Abstract: Described are embodiments of an invention for detecting target antigens in a biological sample using a sample assembly. Detection may be accomplished by performing a method comprising: sweeping a head module over the sample assembly, wherein said head module includes at least one magneto-resistive read sensor configured to detect target antigens via nanoparticles within the sample assembly; and detecting at least one particular antigen among the target antigens. Preferably, detecting the target antigens via the nanoparticles is based at least in part on detecting unique magnetic properties of particular nanoparticles specifically associated with different types of the target antigens. Detection using a magnetic read/write head in the sample assembly facilitates automation of sample detection with high speed and fidelity. Corresponding systems are also disclosed.Type: GrantFiled: April 11, 2016Date of Patent: July 20, 2021Assignee: International Business Machines CorporationInventors: Dylan J. Boday, Stephen L. Schwartz, Anna W. Topol, Sandra L. Waters, Daniel J. Winarski
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Patent number: 10656232Abstract: Described are embodiments to calibrate read sensors, which in turn may ensure that the equipment utilized to detect antigens is reliable and accurate. If it is determined that a read sensor is degraded a method of calibrating a read sensor of a read head may be used.Type: GrantFiled: September 26, 2014Date of Patent: May 19, 2020Assignee: International Business Machines CorporationInventors: David Berman, Dylan J. Boday, Icko E. T. Iben, Wayne I. Imaino, Stephen L. Schwartz, Anna W. Topol, Daniel J. Winarski
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Publication number: 20190317160Abstract: The inventive concepts presented herein relate to methods of identifying molecules identification of molecules using apparatuses including: electromagnetic write-head(s); magneto-resistive read sensor(s), and processor(s). An exemplary method includes scanning one or more of a plurality of biosample tracks of a biosample substrate using an electromagnetic write-head to magnetically excite one or more molecules of interest using an alternating magnetic field. The one or more molecules of interest are disposed on one or more of the biosample tracks. A resonant response of the one or more molecules of interest is measured using a magneto-resistive sensor. The resonant response is compared to a table of known resonant responses to identify the one or more molecules of interest.Type: ApplicationFiled: May 28, 2019Publication date: October 17, 2019Inventors: Allen K. Bates, Anna W. Topol, Daniel J. Winarski
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Patent number: 10393737Abstract: Described are embodiments of an invention for a sample assembly with an electrical conductor for detection of the antigens by electromagnetic read heads. In one embodiment, a sample assembly includes: a substrate; one or more base layers above the substrate; an outer layer above the substrate; a plurality of sample trenches formed in the outer layer, each sample trench being characterized by an upper surface, a bottom surface, and a longitudinal axis; an electrical conductor disposed in the substrate, the electrical conductor being configured to generate an electromagnetic field in proximity to the plurality of sample trenches to enhance nanoparticle movement toward the bottom surface of the plurality of sample trenches; and at least one alignment trench formed above the substrate, each alignment trench having a longitudinal axis substantially parallel to a longitudinal axis of at least one of the sample trenches.Type: GrantFiled: May 31, 2016Date of Patent: August 27, 2019Assignee: International Business Machines CorporationInventors: Allen K. Bates, Nils Haustein, Stephen L. Schwartz, Anna W. Topol, Daniel J. Winarski
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Patent number: 10371762Abstract: The inventive concepts presented herein relate to methods of identifying molecules identification of molecules using apparatuses including: electromagnetic write-head(s); magneto-resistive read sensor(s), and processor(s). An exemplary method includes magnetically exciting a molecule to be identified using an alternating magnetic field generated by an electromagnetic write-head, measuring a resonant response of the molecule to be identified using a magneto-resistive read sensor; and comparing, using a processor, the resonant response of the molecule to be identified with a table of known resonant responses to identify a chemical composition of the molecule to be identified. The molecule to be identified may optionally be disposed on a biosample substrate which comprises, or is coupled to, a plurality of servo-alignment marks; and the plurality of servo-alignment marks are configured to facilitate alignment of the electromagnetic write-head with the biosample tracks of the biosample substrate.Type: GrantFiled: April 25, 2018Date of Patent: August 6, 2019Assignee: International Business Machines CorporationInventors: Allen K. Bates, Anna W. Topol, Daniel J. Winarski
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Patent number: 10359439Abstract: Embodiments of the disclosure relate to a biosample plate that includes a memory component for storing biosample identification and analysis data, and a wireless communication interface for transferring the data to and from the biosample plate. In one embodiment, the biosample plate comprises a base for receiving a biosample, a memory component coupled to the base for storing identification and analysis information related to the biosample, and a wireless communication interface coupled to the memory component for transferring the information to and from the memory component. The wireless communication interface may include an electromagnetic device.Type: GrantFiled: July 19, 2016Date of Patent: July 23, 2019Assignee: International Business Machines CorporationInventors: Nils Haustein, Thorsten Krause, Anna W. Topol, Daniel J. Winarski
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Patent number: 10317398Abstract: A sample assembly includes an outer layer with at least one sample trench. The sample trench includes a first set of antibodies that are bonded on a first surface of a base layer. Target antigens are bonded with the first set of antibodies, and a second set of antibodies are bonded to the target antigens. Further, the sample trench includes nanoparticles that are bonded to the second set of antibodies.Type: GrantFiled: September 29, 2015Date of Patent: June 11, 2019Assignee: International Business Machines CorporationInventors: Dylan J. Boday, Stephen L. Schwartz, Anna W. Topol, Sandra L. Waters, Daniel J. Winarski
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Patent number: 10296711Abstract: A system, method and computer program product for archiving image, audio, and text data with metadata encapsulation in a client-server storage library is described. The server receives and holds the images, audio, or text to be archived in an image, audio or text logical partition which includes a directory of the images, audio, or text. The information is encapsulated in a metadata wrapper and stored in the library as a closed image, audio, or text file along with a closed copy of the directory. The closed image, audio, or text directory is also stored in the client. The images may be encapsulated in MXF, DICOM, Tape Archive (TAR) or GZIP formats. The storage library may have magnetic tapes, magnetic disks or optical disks as storage media.Type: GrantFiled: May 17, 2010Date of Patent: May 21, 2019Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Allen Keith Bates, Louie Arthur Dickens, Timothy A. Johnson, Craig Anthony Klein, Yun Mou, Stephen Leonard Schwartz, Anna W. Topol, Daniel James Winarski
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Patent number: 10261102Abstract: Embodiments of the disclosure relate to a biosample plate that includes a memory component for storing biosample identification and analysis data, and a wireless communication interface for transferring the data to and from the biosample plate. In one embodiment, the biosample plate comprises a base for receiving a biosample, a memory component coupled to the base for storing identification and analysis information related to the biosample, and a wireless communication interface coupled to the memory component for transferring the information to and from the memory component. The wireless communication interface may include an electromagnetic device.Type: GrantFiled: October 8, 2015Date of Patent: April 16, 2019Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Nils Haustein, Thorsten Krause, Anna W. Topol, Daniel J. Winarski
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Patent number: 10209266Abstract: Embodiments of the disclosure relate to a biosample plate that includes a memory component for storing biosample identification and analysis data, and a wireless communication interface for transferring the data to and from the biosample plate. In one embodiment, the biosample plate comprises a base for receiving a biosample, a memory component coupled to the base for storing identification and analysis information related to the biosample, and a wireless communication interface coupled to the memory component for transferring the information to and from the memory component. The wireless communication interface may include an optical device.Type: GrantFiled: October 8, 2015Date of Patent: February 19, 2019Assignee: International Business Machines CorporationInventors: Nils Haustein, Thorsten Krause, Anna W. Topol, Daniel J. Winarski
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Patent number: 10132804Abstract: Described are embodiments of an invention for a sample assembly with an electrical conductor for detection of the antigens by electromagnetic read heads. In one embodiment, a sample assembly includes: a substrate; one or more base layers above the substrate; an outer layer above the one or more base layers; a plurality of sample trenches formed in the outer layer and/or the one or more base layers, each sample trench being characterized by an upper surface, a bottom surface, and a longitudinal axis; an electrical conductor disposed in the substrate, the electrical conductor being configured to generate an electromagnetic field in proximity to the plurality of sample trenches to enhance nanoparticle movement toward the bottom surface of the plurality of sample trenches; and at least one alignment trench formed above the substrate, each alignment trench having a longitudinal axis substantially parallel to a longitudinal axis of at least one of the sample trenches.Type: GrantFiled: May 31, 2016Date of Patent: November 20, 2018Assignee: International Business Machines CorporationInventors: Allen K. Bates, Nils Haustein, Stephen L. Schwartz, Anna W. Topol, Daniel J. Winarski
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Publication number: 20180246176Abstract: The inventive concepts presented herein relate to methods of identifying molecules identification of molecules using apparatuses including: electromagnetic write-head(s); magneto-resistive read sensor(s), and processor(s). An exemplary method includes magnetically exciting a molecule to be identified using an alternating magnetic field generated by an electromagnetic write-head, measuring a resonant response of the molecule to be identified using a magneto-resistive read sensor; and comparing, using a processor, the resonant response of the molecule to be identified with a table of known resonant responses to identify a chemical composition of the molecule to be identified. The molecule to be identified may optionally be disposed on a biosample substrate which comprises, or is coupled to, a plurality of servo-alignment marks; and the plurality of servo-alignment marks are configured to facilitate alignment of the electromagnetic write-head with the biosample tracks of the biosample substrate.Type: ApplicationFiled: April 25, 2018Publication date: August 30, 2018Inventors: Allen K. Bates, Anna W. Topol, Daniel J. Winarski
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Patent number: 10052634Abstract: Embodiments of the disclosure relate to methods of storing and using biosamples with a cartridge that includes slots for storing biosample capillary tubes. The methods include providing access to a holder inside an enclosure of the cartridge, the enclosure having a same form factor as a data tape cartridge used in an automated tape library. The holder is configured to receive a plurality of capillary tubes in the holder, the capillary tubes including one or more biosamples. Exemplary methods may also include receiving capillary tubes in the cartridge, withdrawing capillary tubes from the cartridge, scanning and/or analyzing the capillary tubes and/or biosamples. Exemplary methods may additionally or alternatively include retrieving the cartridge from a storage slot of the automated tape library, loading the cartridge onto a drive of the automated tape library, and/or receiving and/or exporting a cartridge to/from the automated tape library via a mail slot.Type: GrantFiled: February 25, 2016Date of Patent: August 21, 2018Assignee: International Business Machines CorporationInventors: Allen K. Bates, Nils Haustein, James W. Johnson, Thorsten Krause, Stephen L. Schwartz, Anna W. Topol, Ulf Troppens, Daniel J. Winarski
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Patent number: 10012706Abstract: The invention relates to the identification of molecules using an apparatus which includes: a head module comprising: an electromagnetic write-head configured to magnetically excite the molecule to be identified with an alternating magnetic field; and a magneto-resistive read sensor for measuring a resonant response of the magnetically excited molecule to be identified. The apparatus also includes a processor coupled to the magneto-resistive sensor, the processor being configured to compare the resonant response to a table of known resonant responses to identify a chemical composition of the molecule to be identified.Type: GrantFiled: April 7, 2016Date of Patent: July 3, 2018Assignee: International Business Machines CorporationInventors: Allen K. Bates, Anna W. Topol, Daniel J. Winarski
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Patent number: 9714985Abstract: According to one embodiment, a calibration assembly includes an outer layer having at least one calibration trench extending along a y-axis, and an encapsulation layer within the calibration trench. The encapsulation layer has a plurality of nanoparticles spaced apart along said y-axis of said at least one calibration trench. Each of said plurality of nanoparticles are provided at known y-axis locations in said calibration trench, and each of the plurality of nanoparticles have a known magnetic property.Type: GrantFiled: December 12, 2014Date of Patent: July 25, 2017Assignee: GLOBALFOUNDRIES INC.Inventors: David Berman, Dylan J. Boday, Icko E. T. Iben, Wayne I. Imaino, Stephen L. Schwartz, Anna W. Topol, Daniel J. Winarski
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Publication number: 20160327584Abstract: Embodiments of the disclosure relate to a biosample plate that includes a memory component for storing biosample identification and analysis data, and a wireless communication interface for transferring the data to and from the biosample plate. In one embodiment, the biosample plate comprises a base for receiving a biosample, a memory component coupled to the base for storing identification and analysis information related to the biosample, and a wireless communication interface coupled to the memory component for transferring the information to and from the memory component. The wireless communication interface may include an electromagnetic device.Type: ApplicationFiled: July 19, 2016Publication date: November 10, 2016Inventors: Nils Haustein, Thorsten Krause, Anna W. Topol, Daniel J. Winarski
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Publication number: 20160274102Abstract: Described are embodiments of an invention for a sample assembly with an electrical conductor for detection of the antigens by electromagnetic read heads. In one embodiment, a sample assembly includes: a substrate; one or more base layers above the substrate; an outer layer above the one or more base layers; a plurality of sample trenches formed in the outer layer and/or the one or more base layers, each sample trench being characterized by an upper surface, a bottom surface, and a longitudinal axis; an electrical conductor disposed in the substrate, the electrical conductor being configured to generate an electromagnetic field in proximity to the plurality of sample trenches to enhance nanoparticle movement toward the bottom surface of the plurality of sample trenches; and at least one alignment trench formed above the substrate, each alignment trench having a longitudinal axis substantially parallel to a longitudinal axis of at least one of the sample trenches.Type: ApplicationFiled: May 31, 2016Publication date: September 22, 2016Inventors: Allen K. Bates, Nils Haustein, Stephen L. Schwartz, Anna W. Topol, Daniel J. Winarski
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Publication number: 20160274099Abstract: Described are embodiments of an invention for a sample assembly with an electrical conductor for detection of the antigens by electromagnetic read heads. In one embodiment, a sample assembly includes: a substrate; one or more base layers above the substrate; an outer layer above the substrate; a plurality of sample trenches formed in the outer layer, each sample trench being characterized by an upper surface, a bottom surface, and a longitudinal axis; an electrical conductor disposed in the substrate, the electrical conductor being configured to generate an electromagnetic field in proximity to the plurality of sample trenches to enhance nanoparticle movement toward the bottom surface of the plurality of sample trenches; and at least one alignment trench formed above the substrate, each alignment trench having a longitudinal axis substantially parallel to a longitudinal axis of at least one of the sample trenches.Type: ApplicationFiled: May 31, 2016Publication date: September 22, 2016Inventors: Allen K. Bates, Nils Haustein, Stephen L. Schwartz, Anna W. Topol, Daniel J. Winarski