Abstract: A computing system security dashboard is provided for presentation on a computer display device, the dashboard including a plurality of security view panes. Each security view pane, when expanded, presents a respective visualization of security conditions of a particular computing system. When the particular security view pane is collapsed it can hide at least a portion of particular visualizations of security conditions presented using the particular security view pane when expanded. The particular security view pane occupies a smaller area of the dashboard when collapsed than when expanded. A particular visual indicator is presented on the particular security view, at least when collapsed, summarizing at least a portion of the particular security conditions identified in the particular visualizations. A user interaction with the particular collapsed security view pane can prompt the particular security view pane to be expanded in area and present the particular visualizations.

Abstract: A cutting element comprises a supporting substrate, and a cutting table attached to the supporting substrate and comprising a substantially planar apex, opposing flat surfaces extending upwardly and inwardly toward the substantially planar apex from locations proximate an interface between the cutting table and the supporting substrate, primary edge surfaces between the substantially planar apex and the opposing flat surfaces and exhibiting one or more of a radiused geometry and a chamfered geometry, opposing semi-conical surfaces intervening between the opposing flat surfaces and extending upwardly and inwardly toward the substantially planar apex from other locations proximate the interface between the cutting table and the supporting substrate, and secondary edge surfaces between the substantially planar apex and the opposing semi-conical surfaces and exhibiting one or more of another radiused geometry and another chamfered geometry.

Abstract: This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.

Abstract: A self-adjusting earth-boring tool includes a body carrying cutting elements and an actuation device disposed at least partially within the body. The actuation device may include a first fluid chamber, a second fluid chamber, a first reciprocating member, and a second reciprocating member. The first and second reciprocating members may divide portions of the first fluid chamber from portions of the second fluid chamber. A connection member may be attached to both of the first and second reciprocating members and may have a drilling element removably coupled thereto. A first fluid flow path may extend from the second fluid chamber to the first fluid chamber. A second fluid flow path may extend from the first fluid chamber to the second fluid chamber.

Abstract: Connexin protein modulation methods and compositions are provided for the healing of resistant lesions, including lesions on subjects with multiple venous leg ulcers or multiple diabetic foot ulcers, and other responder subjects. Also provided are kits and articles of manufacture comprising a connexin protein modulating agent, for example, a connexin 43 modulating agent for use in the healing of resistant lesions.

Abstract: A plurality of security events is detected in a computing system, each security event based on at least one policy in a plurality of security policies. Respective interactive graphical representations are presented in a graphical user interface (GUI) of either or both of the security events or security policies. The representations include interactive graphical elements representing the respective security events or security policies. User selection of a particular event element via the interactive GUI causes a subset of the security policies to be identified, each security policy in the subset serving as a basis for at least one particular security event represented by the particular event element. User selection of a particular policy element via the interactive GUI causes a subset of the security policies to be identified, each security event in the subset based at least in part on a particular security policy represented by the particular policy element.

Abstract: This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.

Abstract: Methods and compositions for treating neurological damage or dysfunction are described, including methods implemented by administration of peptide inhibitors of AMPA receptor endocytosis.

Abstract: This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.

Abstract: The inventions relate to compositions and articles of manufacture comprising connexin modulators, pannexin modulators, gap junction modulators, hemichannel modulators, and pannexin channel modulators and their use, alone or in combination, in treating ocular and other disorders.

Abstract: A device for mitigation of temporomandibular joint disorder with lingual tooth surface contact surface, hard palate conformity, anterior pad, and pad wings.

Abstract: This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.

Abstract: One aspect of the invention relates to customized thin-film composite membranes comprising: a porous support; a selective barrier; and one or more polymeric additives dispersed in the porous support in an amount from at least about 1% and about 50% by weight of the porous support. Another aspect of the invention relates to a method of fabricating a porous support comprising the steps of: preparing a polymer solution comprising a polymer, a polymeric additive, and a first liquid; contacting a surface with the polymer solution; and evaporating the liquid. Another aspect of the invention relates to the use of the thin-film composite membranes disclosed herein in osmotically driven membrane processes.

Abstract: This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.

Abstract: A reaming bit designed to operate with low torque fluctuation when driven with a turbine at speeds in the order of 300-600 RPM and above features a profile that is arcuate from the gauge dimension to the nose area or alternatively has a blunt straight taper section but with a ratio of profile length (PL) to bit size (BS) of under 0.75. The blades extend into a concave cone and the cutting structure continues along the blades towards the center. The blades have a step near the gauge section to increase the exposure of the blade cutting structure. An array of protrusions are disposed parallel to and behind the cutting structure to increase high speed stability and adjacent the blade step transition to protect outer casing on run in.

Abstract: The invention relates to repairing and/or modifying a surface of a membrane in osmotically driven membrane systems by the introduction of one or more substances to the membrane.

Abstract: A reaming bit designed to operate with low torque fluctuation when driven with a turbine at speeds in the order of 300-600 RPM and above features a profile that is arcuate from the gauge dimension to the nose area or alternatively has a blunt straight taper section but with a ratio of profile length (PL) to bit size (BS) of under 0.75. The blades extend into a concave cone and the cutting structure continues along the blades towards the center. The blades have a step near the gauge section to increase the exposure of the blade cutting structure. An array of protrusions are disposed parallel to and behind the cutting structure to increase high speed stability and adjacent the blade step transition to protect outer casing on run in.

Abstract: A plurality of security events is detected in a computing system, each security event based on at least one policy in a plurality of security policies. Respective interactive graphical representations are presented in a graphical user interface (GUI) of either or both of the security events or security policies. The representations include interactive graphical elements representing the respective security events or security policies. User selection of a particular event element via the interactive GUI causes a subset of the security policies to be identified, each security policy in the subset serving as a basis for at least one particular security event represented by the particular event element. User selection of a particular policy element via the interactive GUI causes a subset of the security policies to be identified, each security event in the subset based at least in part on a particular security policy represented by the particular policy element.

Abstract: A reaming bit designed to operate with low torque fluctuation when driven with a turbine at speeds in the order of 300-600 RPM and above features a profile that is arcuate from the gauge dimension to the nose area or alternatively has a blunt straight taper section but with a ratio of profile length (PL) to bit size (BS) of under 0.75. The blades extend into a concave cone and the cutting structure continues along the blades towards the center. The blades have a step near the gauge section to increase the exposure of the blade cutting structure. An array of protrusions are disposed parallel to and behind the cutting structure to increase high speed stability and adjacent the blade step transition to protect outer casing on run in.

Abstract: This invention concerns improved methods, uses, and kits for treating chronic wounds through the administration of anti-connexin agents, particularly anti-connexin 43 antisense polynucleotides. The methods, uses, and kits of the invention are based on the surprising and unexpected discovery that chronic wounds that do not increase or decrease in size by more than a pre-determined amount during a pre-treatment phase are more amenable to successful treatment than wounds whose size varies outside the target range during the pre-treatment phase.