Abstract: A liquid transfer device is disclosed that has a fluid pump enclosed within a rigid, space enclosing housing. The pump has a strainer with strainer openings that provide a fluid connection between the pump and the inside of the housing. The strainer is located at the lower end of the pump and the housing. There are also openings in the housing that provide a fluid connection between the inside of the housing and its outer surface. The maximum size of the openings in the housing is less than the minimum size of the strainer openings so that the strainer does not clog with debris. A discharge manifold provides a fluid connection between the pump and the outside the housing. In this way fluid is drawn in through the housing openings and then the strainer before being pumped out via the discharge manifold.

Abstract: A liquid transfer device having a housing with a top end, a bottom end, a sidewall, and an inner cavity. The sidewall has an inner surface and an outer surface. There is a plurality of openings traversing said sidewall. Also present is a filtering surface that covers the openings. The water or other liquids are pumped or transferred with a pump contained inside the inner cavity, with a fluid exit used for carrying the water out towards exterior hosing.

Abstract: A liquid transfer device having a housing with a top end, a bottom end, a sidewall, and an inner cavity. The sidewall has an inner surface and an outer surface. There is a plurality of openings traversing said sidewall. Also present is a filtering surface that covers the openings. The water or other liquids are pumped or transferred with a pump contained inside the inner cavity, with a fluid exit used for carrying the water out towards exterior hosing.

Abstract: A video display device comprising a casing having a front wall and a rear wall. The front wall defines an opening for display screen. The rear wall has formed therein a plurality of clip-receiving portions. The plurality of clip-receiving portions face outwardly of the casing and have a predetermined spacing relative to one another. Each of the plurality of clip receiving portions is configured to receive from outside the casing a respective clip for receiving a fastener for mounting the video display device.

Abstract: A display device may be mounted on a stand. The stand may present a display screen of the display device at an angle in which it is easy for the user to view the display screen. The desired tilt angle of the display screen may vary depending on where it is positioned, and where it is viewed from. The present invention provides a stand in which the tilt angle of a display device can be changed between at least two different angles. The display device is securely mounted to the stand at all tilt angles.

Abstract: A low maintenance condenser for using in commercial refrigeration systems comprising a single metallic flat section having two or more integrally formed pipes for the flowing of a refrigerant fluid and a flat longitudinal heat dissipation section at each side of a pipe, wherein the first end of the first pipe comprising the refrigerant fluid inlet and the second end of the last pipe comprising the fluid outlet, and wherein the first end of the next pipe is connected to the second end of the previous pipe, successively until the last pipe, in order to form a single circuit having a single refrigerant fluid inlet and a single refrigerant fluid outlet.

Abstract: The invention relates to a device for fixing metallic structures to the floor, said device consisting of a cylindrical metallic tube (2) with lateral wings (4) and longitudinal openings, in the lower part, from which teeth (11) extend, said teeth being distributed over the external surface of link blocks (9) which expand by screwing a central screw (5) fixed thereto by an upper jig bushing (6), and two central and lower jig bushings (7) that hold and guide the link blocks (9). Pistons (12) are arranged in the region of the openings (3), said pistons moving in opposite directions towards the centre of said region due to the screw (5) having reverse screws in its screwing areas, which push the link blocks (9) outwards during the movement of the pistons, causing the teeth to project out of the tube (2) through the openings (3). The upper end (16) of the screw (5) is hexagonal.

Abstract: A liquid transfer device having a housing with a top end, a bottom end, a sidewall, and an inner cavity. The sidewall has an inner surface and an outer surface. There is a plurality of openings traversing said sidewall. Also present is a filtering surface that covers the openings. The water or other liquids are pumped or transferred with a pump contained inside the inner cavity, with a fluid exit used for carrying the water out towards exterior hosing.

Abstract: A video display device comprising a casing having a front wall and a rear wall. The front wall defines an opening for display screen. The rear wall has formed therein a plurality of clip-receiving portions. The plurality of clip-receiving portions face outwardly of the casing and have a predetermined spacing relative to one another. Each of the plurality of clip receiving portions is configured to receive from outside the casing a respective clip for receiving a fastener for mounting the video display device.

Abstract: A display device may be mounted on a stand. The stand may present a display screen of the display device at an angle in which it is easy for the user to view the display screen. The desired tilt angle of the display screen may vary depending on where it is positioned, and where it is viewed from. The present invention provides a stand in which the tilt angle of a display device can be changed between at least two different angles. The display device is securely mounted to the stand at all tilt angles.

Abstract: A process for obtaining a crab meat substitute from shark—prionace glauca—meat wherein a product is obtained having quality, taste, odor, color and appearance similar to crab meat. It can use blue shark meat as raw material, which is a widely distributed shark around the world without restrictions. The raw material is freshly stored and shredded. It has a larger volume in the manufacturing process. It can be commercialized both preserved and frozen. The quality and final taste is almost identical to that of crab meat.

Abstract: The present invention relates to intermediates useful in the synthesis of Dolasetron and synthetic precursors thereof, as well as to processes for obtaining them. In addition, it refers to the hydrochloric salt of Dolasetron and polymorphic forms of Dolasetron and precursors thereof.

Abstract: The present invention relates to a method for obtaining Dolasetron that comprises: a) Esterification of the alcohol of formula (IV) with indole-3-carboxylic acid (compound (III)) or a reactive derivative thereof, to give a compound of formula (V), followed by step b) which includes Dieckmann reaction of the intermediate (V), by reaction with a strong organic or inorganic base, to give the intermediate (VI), and step c) which comprises dealcoxycarbonylation of the intermediate (VI) to give Dolasetron base and, if desired, a pharmaceutically acceptable salt thereof, hydrates or solvates of the base of said salt. The invention also relates to the intermediates (V) and (VI), and methods for obtaining them. With the method of the present invention Dolasetron is obtained at industrial scale with good yields, with decreased use of reactants and solvents, while said method is also of greater atomic efficiency.

Abstract: This invention relates to a process for preparing intermediates useful in preparing Valsartan and to a process for preparing the latter, together with synthesis intermediates of formula (IV), (V) and (VI), useful for manufacturing a medicament for the treatment of arterial hypertension or heart failure. The process for preparing Valsartan permits it to be prepared on an industrial scale with high yields and without racemisation problems, in addition to using simple and available starting products. The invention also provides a process for preparing the intermediate of formula (VI), from an intermediate of formula (V) that does not require protection of the carboxylic acid prior to N-acylation.

Abstract: The invention relates to the graded expression level of SNAIL gene or its expression products, as a marker of the capacity of epithelial and mesenchymal tumours and/or cancers for disseminating to other tissues or organs. The invention further relates to a transgenic non-human mammal comprising in its genome a transgene that comprises a nucleic acid sequence encoding the SNAIL protein, and the use of SNAIL as a marker of epithelial and mesenchymal tumours and/or cancers as well as in DNA damage-based diseases In addition, the invention relates to the use of SNAIL as a therapeutic and diagnostic target for said pathologies.

Abstract: This invention relates to a process for preparing intermediates useful in preparing Valsartan and to a process for preparing the latter, together with synthesis intermediates of formula (IV), (V) and (VI), useful for manufacturing a medicament for the treatment of arterial hypertension or heart failure. The process for preparing Valsartan permits it to be prepared on an industrial scale with high yields and without racemisation problems, in addition to using simple and available starting products. The invention also provides a process for preparing the intermediate of formula (VI), from an intermediate of formula (V) that does not require protection of the carboxylic acid prior to N-acylation.

Abstract: The present invention relates to intermediates useful in the synthesis of Dolasetron and synthetic precursors thereof, as well as to processes for obtaining them. In addition, it refers to the hydrochloric salt of Dolasetron and polymorphic forms of Dolasetron and precursors thereof.

Abstract: The present invention relates to a method for obtaining Dolasetron that comprises: a) Esterification of the alcohol of formula (IV) with indole-3-carboxylic acid (compound (III)) or a reactive derivative thereof, to give a compound of formula (V), followed by step b) which includes Dieckmann reaction of the intermediate (V), by reaction with a strong organic or inorganic base, to give the intermediate (VI), and step c) which comprises dealcoxycarbonylation of the intermediate (VI) to give Dolasetron base and, if desired, a pharmaceutically acceptable salt thereof, hydrates or solvates of the base of said salt. The invention also relates to the intermediates (V) and (VI), and methods for obtaining them. With the method of the present invention Dolasetron is obtained at industrial scale with good yields, with decreased use of reactants and solvents, while said method is also of greater atomic efficiency.

Abstract: The present invention refers to a process for the synthesis of (1-{1-(R)-(E)-{3-[2-(7-chloro-quinolin-2-yl)-vinyl]-phenyl}-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid or its salts, comprising the reaction between 7-Chloro-2-vinyl-quinoline and a compound of formula (I) wherein X is a halogen atom or a group of formula —OSO2R, wherein R is selected from the group consisting of CF3, tolyl, methyl and F; in the presence of a palladium based catalyst. The invention is also directed to intermediates compounds of the process.

Abstract: A watch is provided in which a movement pivots in a case and comprises a mechanism for correcting display organs. In one implementation of the watch, an assembly member is constructed such that, in at least one predefined position, the movement occupies a defined position in the case. Moreover, a control system is provided which comprises a button accessible from outside of the case, a stem attached to the button and passing through the case, and a connecting member designed to connect the button to the correcting mechanism and constructed in such a way that, in the defined position, it can be connected to the stem.