Abstract: An electric powertrain includes a first electric motor that has an uninterrupted connection with a drive shaft of a vehicle. The electric powertrain further includes a second electric motor that has an interruptible connection with the drive shaft. In one form, this interruptible connection includes a clutch. The electric powertrain further includes a first gear train in the form of a first planetary gear and a second gear train in the form of a second planetary gear. In one form, the first electric motor and second electric motor are the same type of electric motor, and in another form, the first electric motor and second electric motor are different types of electric motors.

Abstract: An interlockable structural panel with a channel cross-section including a base and first and second side wall forming the sides of the channel, wherein an end of the first side wall distal the base is curved as a first arc directed away from a central portion of the channel and an end of the second side wall is curved as a second arc directed towards the central portion of the channel and wherein a straight section extends from the end of the second arc distal the base. Also methods for forming interlockable structural panels and for forming curved interlockable structural panels for constructions including roofs.

Abstract: Various implementations include computing devices and related computer-implemented methods for rendering a scene in an augmented audio environment. Certain implementations include approaches for generating application programming interface (API) inputs on a display. Additional implementations include approaches for rendering the API inputs at an audio device.

Abstract: Various implementations include computing devices and related computer-implemented methods for rendering a scene in an augmented audio environment. Certain implementations include approaches for generating application programming interface (API) inputs on a display. Additional implementations include approaches for rendering the API inputs at an audio device.

Abstract: Various implementations include audio devices and related computer-implemented methods for controlling playback of augmented reality (AR) audio. Certain implementations include approaches for initiating AR audio playback at an audio device independent of a detected geographic location of the device. Additional implementations include approaches for initiating AR audio playback based upon one or more geographic location-specific indicators for the device.

Abstract: An interlockerable structural panel (4) with a channel cross-section including a base 3) and first (52) and second side wall (51) forming the sides of the channel, wherein an end of the first side wall distal the base is curved as a first arc (13) directed away from a central portion of the channel and an end of the second side wall is curved as a second arc (23) directed towards the central portion of the channel and wherein a straight section (24) extends from the end of the second arc (23) distal the base (3).

Abstract: This invention relates to a dosage management system that comprises a container including a box with an opening towards the top. The box has a first side with an opposing second side and a third side. The box has a pair of parallel grooves in the first side and second side and a tray inside the box. There is also provided a resilient sliding lid. The lid has two parallel opposing edges that slidingly engage the grooves. At least one of the edges and grooves has a catch and notch combination that engage when the lid is in a closed position. The grooves have a first incline or decline part connected to a substantially horizontal part which is again connected to a second incline or decline part. When opening the box, the lid is pushed down the lid then bending into the horizontal part, the notch and catch disengaging and the lid is moved to the third side to open the box.

Abstract: This invention relates to a dosage management system that comprises a container including a box with an opening towards the top. The box has a first side with an opposing second side and a third side. The box has a pair of parallel grooves in the first side and second side and a tray inside the box. There is also provided a resilient sliding lid. The lid has two parallel opposing edges that slidingly engage the grooves. At least one of the edges and grooves has a catch and notch combination that engage when the lid is in a closed position. The grooves have a first incline or decline part connected to a substantially horizontal part which is again connected to a second incline or decline part. When opening the box, the lid is pushed down the lid then bending into the horizontal part, the notch and catch disengaging and the lid is moved to the third side to open the box.

Abstract: The present invention provides methods and compositions for inducing expression of Ube3a in a cell by contacting the cell with a topoisomerase inhibitor. Particular embodiments include a method of treating a genomic imprinting disorder, such as Angelman syndrome, in a subject by administering to the subject an effective amount of a topoisomerase inhibitor.

Abstract: An interlockerable structural panel (4) with a channel cross-section including a base 3) and first (52) and second side wall (51) forming the sides of the channel, wherein an end of the first side wall distal the base is curved as a first arc (13) directed away from a central portion of the channel and an end of the second side wall is curved as a second arc (23) directed towards the central portion of the channel and wherein a straight section (24) extends from the end of the second arc (23) distal the base (3).

Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof and N-oxides thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds and the uses of such compounds for the treatment of D1-mediated (or D1-associated) disorders including cognitive and motivational impairments and negative symptoms associated with illnesses such as schizophrenia, depression, bipolar disorder, Parkinson's disease, Mild cognitive impairment (MCI), Alzheimer's disease, lupus, Huntington's disease, Parkinson's, dyskinesia, ADHD, post-traumatic stress disorder, autism spectrum disorder, treatment-resistant depression, major depressive disorder (MDD), drug dependence, Tourette's syndrome, tardive dyskinesias as well as impairments associated with age, chronic stress, sleep deprivation, combat, chronic fatigue; endocrine or metabolic diseases such as hyperglycemia, dislipidemia, diabetes, obesity, and sepsis; and c

Abstract: A first remote memory access link is established between a first communications interface card on the first computing device and a second communications interface card on the second computing device. In response to an error associated with the first remote memory access link, messages are copied from a segmented queue associated with the first communications interface card to a segmented queue associated with a third communications interface card on the first computing device. A second remote memory access link between the third communications interface card and a fourth communications interface card is activated on the second computing device, and messages are resent from the segmented queue associated with the third communications interface card to the fourth communications interface card through the second remote memory access link. The second computing device discards duplicate received messages, if any.

Abstract: The present invention provides methods and compositions for inducing expression of Ube3a in a cell by contacting the cell with a topoisomerase inhibitor. Particular embodiments include a method of treating a genomic imprinting disorder, such as Angelman syndrome, in a subject by administering to the subject an effective amount of a topoisomerase inhibitor.

Abstract: A writing application on a computing device can reference a tail pointer to write messages to message buffers that a peer-to-peer data link replicates in memory of another computing device. The message buffers are divided into at least two queue segments, where each segment has several buffers. Messages are read from the buffers by a reading application on one of the computing devices using an advancing head pointer by reading a message from a next message buffer when determining that the next message buffer has been newly written. The tail pointer is advanced from one message buffer to another within a same queue segment after writing messages. The tail pointer is advanced from a message buffer of a current queue segment to a message buffer of a next queue segment when determining that the head pointer does not indicate any of the buffers of the next queue segment.

Abstract: The present invention provides methods and compositions for inducing expression of Ube3a in a cell by contacting the cell with a topoisomerase inhibitor. Particular embodiments include a method of treating a genomic imprinting disorder, such as Angelman syndrome, in a subject by administering to the subject an effective amount of a topoisomerase inhibitor.

Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof and N-oxides thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds (N-oxides thereof or or pharmaceutically acceptable salts of the compound or the N-oxides) and the uses of such compounds (N-oxides thereof or or pharmaceutically acceptable salts of the compound or the N-oxides) for the treatment of D1-mediated (or D1-associated) disorders including cognitive and motivational impairments and negative symptoms associated with illnesses such as schizophrenia, depression, bipolar disorder, Parkinson's disease, Mild cognitive impairment (MCI), Alzheimer's disease, lupus, Huntington's disease, Parkinson's, dyskinesia, ADHD, post-traumatic stress disorder, autism spectrum disorder, treatment-resistant depression, major depressive disorder (MDD), drug dependence, Tourette's syndrome, tardive dyskinesias as well as impairments asso

Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof and N-oxides thereof; processes and intermediates for preparation of; and compositions and uses thereof. The present invention further provides D1 agonists with reduced D1R desensitization, D1 agonists with a reduced ?-arrestin recruitment activity relative to Dopamine, D1 agonists interacting significantly with the Ser188 but not significantly with the Ser202 of a D1R when binding to the D1R, D1 agonists interacting less strongly with the Asp103 and interacting less strongly with the Ser198 of a D1R when binding to the D1R, and their uses.

Abstract: A tool for closing a shipping container door comprises a head with two extensions curving away from the head and having a space between them sufficient to accommodate a bar bracket of a locking bar on a shipping container door. The head also has a handle that can function as a lever, so that when the tool engages the locking bar about the bar bracket, an operator can close and secure the shipping container door. Optionally, the tool also includes other components, such as features to engage other mechanisms useful in shipping, such as locking bars for opening shipping container doors, and twist locks for coupling and uncoupling shipping containers.

Abstract: The invention relates to a tire having a rubber tread comprised of cap/base construction where the tread outer cap rubber layer contains the running surface of the tread and the tread base rubber layer underlies the tread cap layer wherein the base layer provides a transition zone between the tread cap layer and the remainder of the tire carcass and is not intended to be ground-contacting. For this invention, the tread base rubber layer is comprised of three distinct zones, namely a circumferential annular central rubber zone positioned between two lateral annular rubber zones. In one aspect, the rubber tread cap layer and zoned rubber tread base layer are co-extruded together to form an integral tread rubber composite.

Abstract: A load estimation system and method for estimating vehicle load includes a tire rotation counter for generating a rotation count from rotation of a tire; apparatus for measuring distance travelled by the vehicle; an effective radius calculator for calculating effective radius of the tire from the distance travelled and the rotation count; and a load estimation calculator for calculating the load carried by the vehicle tire from the effective radius of the tire. A center of gravity height estimation may be made from an estimated total load carried by the tires supporting the vehicle pursuant to an estimation of effective radius for each tire and a calculated load carried by each tire from respective effective radii.