Abstract: Embodiments described herein are directed to intelligently classifying Web trackers in a privacy preserving manner and mitigating the effects of such Web trackers. As users browse the Web and encounter various Web sites, tracker-related metrics are determined. The metrics are obfuscated to protect the privacy of the user. The obfuscated metrics are provided as inputs to a machine learning model, which is configured to output a classification for the Web trackers associated with the Web sites visited by the user. Depending on the classification, the effects of the Web trackers are mitigated by placing restrictions on the Web trackers. The restrictions for a particular Web tracker may be relaxed based on a level of user engagement a user has with respect to the tracker's associated Web site. By doing so, the compatibility risks associated with tracking prevention are mitigated for Web sites that are relatively important to the user.

Abstract: Disclosed are thermodynamic and multiplication methods concerning CRISPR-Cas systems, and apparatus therefor.

Abstract: Disclosed herein is a system configured to collect and maintain user data within a first party silo while allowing third party data consumers to use the user data in accordance with explicit input from users. The system provides a user with transparency and control with regard to data use by displaying graphical user interfaces configured to receive input indicating whether the user allows or prevents third party data consumers to use his or her data. The system exposes an API that enables the third party data consumers to submit a data query. The system uses the data query to internally analyze a user data set. User data is included in the user data set in accordance with the input. The system is configured to provide, via the API, a result of the analysis to the third party data consumer that submitted the data query without providing the user data set.

Abstract: Example devices and methods for compensating for monitoring a surge protection device are provided. In some embodiments, a device is configured to couple to a surge protection device. The device comprises a processor that is capable of sending a DC current signal. A serial data interface is electrically connected to the processor and includes at least one shift register. The device also comprises a multiplexer coupled to the serial data interface. The serial data interface is operable to direct the DC current through the multiplexer. The device also comprises an analog to digital converter (optionally embedded within the processor) that is operable to output a digital signal corresponding to a voltage induced by the DC current signal. Returned DC signals represent surge protection device's health and a multitude of other surge module information.

Abstract: Disclosed are thermodynamic and multiplication methods concerning CRISPR-Cas systems, and apparatus therefor.

Abstract: Example devices and methods for compensating for monitoring a surge protection device are provided. In some embodiments, a device is configured to couple to a surge protection device. The device comprises a processor that is capable of sending a DC current signal. A serial data interface is electrically connected to the processor and includes at least one shift register. The device also comprises a multiplexer coupled to the serial data interface. The serial data interface is operable to direct the DC current through the multiplexer. The device also comprises an analog to digital converter (optionally embedded within the processor) that is operable to output a digital signal corresponding to a voltage induced by the DC current signal. Returned DC signals represent surge protection device's health and a multitude of other surge module information.

Abstract: In one aspect, embodiments disclosed herein are directed to engineered CRISPR-Cas effector proteins that comprise at least one modification compared to an unmodified CRISPR-Cas effector protein that enhances binding of the of the CRISPR complex to the binding site and/or alters editing preference as compared to wild type. In certain example embodiments, the CRISPR-Cas effector proteins a Type II effector protein. In certain other example embodiments, the Type V effector protein is Cas9 or an orthologs or engineered variant thereof. Example Cas9 proteins suitable for use in the embodiments disclosed herein are discussed in further detail below.

Abstract: Provided herein are methods of detecting a nucleic acid modification, methods for detecting off-target activity of a targeted nuclease specific for a selected target sequence, methods for determining cleavage efficiency of a targeted nuclease specific for a selected target sequence, methods for selecting a guide RNA from a plurality of guide RNAs specific for a selected target sequence, methods for enrichment of one or more nucleic acid molecules wherein a nucleic acid modification is made and kits of parts for use in such methods.

Abstract: Embodiments disclosed herein are directed to engineered CRISPR-Cas effector proteins that comprise at least one modification compared to an unmodified CRISPR-Cas effector protein that enhances binding of the of the CRISPR complex to the binding site and/or alters editing preference as compared to wild type. In certain example embodiments, the CRISPR-Cas effector protein is a Type V effector protein. In certain other example embodiments, the Type V effector protein is Cpf1. Embodiments disclosed herein are directed to viral vectors for delivery of CRISPR-Cas effector proteins, including Cpf1. In certain example embodiments, the vectors are designed so as to allow packaging of the CRISPR-Cas effector protein within a single vector. There is also an increased interest in the design of compact promoters for packing and thus expressing larger transgenes for targeted delivery and tissue-specificity.

Abstract: Example devices and methods for compensating for monitoring a surge protection device are provided. In some embodiments, a device is configured to couple to a surge protection device. The device comprises a processor that is capable of sending a DC current signal. A serial data interface is electrically connected to the processor and includes at least one shift register. The device also comprises a multiplexer coupled to the serial data interface. The serial data interface is operable to direct the DC current through the multiplexer. The device also comprises an analog to digital converter (optionally embedded within the processor) that is operable to output a digital signal corresponding to a voltage induced by the DC current signal. Returned DC signals represent surge protection device's health and a multitude of other surge module information.

Abstract: Example devices and methods for compensating for monitoring a surge protection device are provided. In some embodiments, a device is configured to couple to a surge protection device. The device comprises a processor that is capable of sending a DC current signal. A serial data interface is electrically connected to the processor and includes at least one shift register. The device also comprises a multiplexer coupled to the serial data interface. The serial data interface is operable to direct the DC current through the multiplexer. The device also comprises an analog to digital converter (optionally embedded within the processor) that is operable to output a digital signal corresponding to a voltage induced by the DC current signal. Returned DC signals represent surge protection device's health and a multitude of other surge module information.

Abstract: A conveyor system including: a track comprising a first magnetic element; and a moving element comprising a second magnetic element for interacting with the track to provide a magnetic force that retains the moving element on the track; wherein absent the magnetic force, the moving element is released from the track. In another aspect, a conveyor system includes: a track having at least one guide rail; and a moving element; wherein a magnetic force controls movement of the moving element in a direction of travel and the magnetic force supports the moving element in a second direction perpendicular to the direction of travel; and wherein the at least one guide rail supports the moving element in a third direction perpendicular to both the direction of travel and the second direction.

Abstract: An automated elevator control system using facial recognition. The system is capable of recognizing an elevator passenger's face in a field of view of an imaging device in close proximity to the elevator car, capturing the elevator passenger's facial image using video data output from the imaging device, and comparing the captured facial image to pre-registered facial image data in a database storing corresponding authorized floor destination data for each passenger. Upon determining a match between the captured facial image and a stored facial image, the system is capable of sending a signal to the elevator control system to move the elevator car to the elevator passenger's authorized floor destination.

Abstract: A system for rental of vehicles stores reservation information for a customer reservation of a rental vehicle, including a scheduled pickup time and pickup location for the rental vehicle. The system receives information from the customer's a mobile device, including image information and location information. When the customer arrives at the rental pickup location, the system prompts the customer to use the mobile device to capture and upload an image of the customer's driver's license, a current image of the customer, and location information for confirming that the customer image was captured at the rental pickup location. The system displays the uploaded driver's license image, the uploaded customer image and the stored reservation information to an operator to verify the identity of the customer before the customer is approved to pick up the rental vehicle.

Abstract: A conveyor system including: a track comprising a first magnetic element; and a moving element comprising a second magnetic element for interacting with the track to provide a magnetic force that retains the moving element on the track; wherein absent the magnetic force, the moving element is released from the track. In another aspect, a conveyor system includes: a track having at least one guide rail; and a moving element; wherein a magnetic force controls movement of the moving element in a direction of travel and the magnetic force supports the moving element in a second direction perpendicular to the direction of travel; and wherein the at least one guide rail supports the moving element in a third direction perpendicular to both the direction of travel and the second direction.

Abstract: Embodiments disclosed herein provide methods for identifying new CRISPR loci and effectors, as well as different CRISPR loci combinations found in various organisms. Class-II CRISPR systems contain single-gene effectors that have been engineered for transformative biological discovery and biomedical applications. Discovery of additional single-gene or multi-component CRISPR effectors may enhance existing CRISPR applications, such as precision genome engineering. Comprehensive characterization of CRISPR-loci may identify novel functional roles of CRISPR loci enabling new tools for biomedicine and biological discovery. CRISPR loci have enormous feature complexity, but classification of CRISPR loci has been focused on a small fraction of highly abundant features. Increased genome sequencing has enhanced the sampling of this feature complexity.

Abstract: There is provided a conveyor system including: a track comprising a first magnetic element; and a moving element comprising a second magnetic element for interacting with the track to provide a magnetic force that retains the moving element on the track; wherein absent the magnetic force, the moving element is released from the track. In another aspect, there is provided a conveyor system that includes: a track having at least one guide rail; and a moving element; wherein a magnetic force controls movement of the moving element in a direction of travel and the magnetic force supports the moving element in a second direction perpendicular to the direction of travel; and wherein the at least one guide rail supports the moving element in a third direction perpendicular to both the direction of travel and the second direction.

Abstract: A reactor apparatus and method for removing and/or reducing NOx, CO, carbon particulates and hydrocarbons from exhaust gases produced by industrial processes includes a reactor including an inlet plenum, a reaction chamber, an outlet plenum, and a heat exchanger wherein gases exiting the reaction chamber heat gases entering the reaction chamber. EGR is drawn through a cooling heat exchanger with an injection blower and is delivered through control valves to the reaction chamber, the inlet plenum and to an add fuel mixing chamber whereby mixed fuel and EGR is delivered to the reaction chamber. A feedback controller controls the flow valves responsive to the temperatures in the reaction chamber entrance and the outlet plenum.