Patents by Inventor Arul M. Chinnaiyan

Arul M. Chinnaiyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for determining a treatment course of action
    Patent number: 11697852
    Abstract: The present disclosure relates to methods of determining a treatment course of action. In particular, the present disclosure relates to mutations in the gene encoding estrogen receptor and their association with responsiveness to estrogen therapies for cancer.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: July 11, 2023
    Assignee: The Regents of the University of Michigan
    Inventors: Arul M. Chinnaiyan, Dan Robinson, Yi-Mi Wu
  • COMPOSITIONS AND METHODS FOR TREATING BREAST CANCER
    Publication number: 20220259674
    Abstract: Provided herein are compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, provided herein are methods of treating basal-like breast cancer based on expression levels of a panel of cancer markers.
    Type: Application
    Filed: February 17, 2022
    Publication date: August 18, 2022
    Inventors: Yuping Zhang, Marcin Cieslik, Arul M. Chinnaiyan, Christopher I. Li
  • Using phage epitopes to profile the immune response
    Patent number: 11307203
    Abstract: The present disclosure provides compositions and methods for using one or more polypeptide probes to profile an immune response. The polypeptide probe can be used to detect one or more antibodies from a sample. Furthermore, the present disclosure provides methods and compositions for characterizing a cancer based on the detection of one or more antibodies, such as autoantibodies.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: April 19, 2022
    Assignees: The Regents of the University of Michigan, Exact Sciences Development Company, LLC
    Inventors: Arul M. Chinnaiyan, Xiaoju Wang, Alex Tsodikov, Jeanne Ohrnberger
  • SYSTEMS AND METHODS FOR DETERMINING A TREATMENT COURSE OF ACTION
    Publication number: 20190271045
    Abstract: The present disclosure relates to methods of determining a treatment course of action. In particular, the present disclosure relates to mutations in the gene encoding estrogen receptor and their association with responsiveness to estrogen therapies for cancer.
    Type: Application
    Filed: January 7, 2019
    Publication date: September 5, 2019
    Inventors: Arul M. Chinnaiyan, Dan Robinson, Yi-Mi Wu
  • Systems and methods for determining a treatment course of action
    Patent number: 10174381
    Abstract: The present disclosure relates to methods of determining a treatment course of action. In particular, the present disclosure relates to mutations in the gene encoding estrogen receptor and their association with responsiveness to estrogen therapies for cancer.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: January 8, 2019
    Assignee: The Regents of the University of Michigan
    Inventors: Arul M. Chinnaiyan, Dan Robinson, Yi-Mi Wu
  • MIPOL1-ETV1 gene rearrangements
    Patent number: 10167517
    Abstract: Compositions and methods associated with recurrent MIPOL1-ETV1 genetic rearrangements that are useful for cancer diagnosis and therapy are disclosed.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: January 1, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul M. Chinnaiyan, Scott Tomlins, Saravana Mohan Dhanasekaran
  • PHAGE MICROARRAY PROFILING OF THE HUMORAL RESPONSE TO DISEASE
    Publication number: 20180265861
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods and compositions for phage microarray profiling of cancer (e.g., prostate, lung, or breast cancer). The present invention further provides novel markers useful for the diagnosis, characterization, and treatment of cancers.
    Type: Application
    Filed: June 4, 2018
    Publication date: September 20, 2018
    Inventors: Arul M. Chinnaiyan, Xiaoju Wang
  • USING PHAGE EPITOPES TO PROFILE THE IMMUNE RESPONSE
    Publication number: 20180224455
    Abstract: The present disclosure provides compositions and methods for using one or more polypeptide probes to profile an immune response. The polypeptide probe can be used to detect one or more antibodies from a sample. Furthermore, the present disclosure provides methods and compositions for characterizing a cancer based on the detection of one or more antibodies, such as autoantibodies.
    Type: Application
    Filed: March 23, 2018
    Publication date: August 9, 2018
    Inventors: Arul M. Chinnaiyan, Xiaoju Wang, Alex Tsodikov, Jeanne Ohrnberger
  • Recurrent gene fusions in prostate cancer
    Patent number: 10041123
    Abstract: Recurrent gene fusions in prostate cancer of androgen regulated genes or housekeeping genes and ETS family member genes are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: August 7, 2018
    Assignee: The Regents of the University of Michigan
    Inventors: Arul M. Chinnaiyan, Scott Tomlins
  • Phage microarray profiling of the humoral response to disease
    Patent number: 10006023
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods and compositions for phage microarray profiling of cancer (e.g., prostate, lung, or breast cancer). The present invention further provides novel markers useful for the diagnosis, characterization, and treatment of cancers.
    Type: Grant
    Filed: January 12, 2016
    Date of Patent: June 26, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul M. Chinnaiyan, Xiaoju Wang
  • Recurrent gene fusions in prostate cancer
    Patent number: 9957569
    Abstract: Recurrent gene fusions in prostate cancer of androgen regulated genes or housekeeping genes and ETS family member genes are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
    Type: Grant
    Filed: November 18, 2008
    Date of Patent: May 1, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul M. Chinnaiyan, Bo Han, Chandan Kumar
  • Recurrent gene fusions in prostate cancer
    Patent number: 9938582
    Abstract: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent gene fusions as diagnostic markers and clinical targets for prostate cancer.
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: April 10, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul M. Chinnaiyan, Xiaosong Wang
  • Recurrent gene fusions in prostate cancer
    Patent number: 9926602
    Abstract: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to recurrent gene fusions as diagnostic markers and clinical targets for prostate cancer.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: March 27, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul M. Chinnaiyan, Xiaosong Wang
  • MIPOL1-ETV1 GENE REARRANGEMENTS
    Publication number: 20170327901
    Abstract: Compositions and methods associated with recurrent MIPOL1-ETV1 genetic rearrangements that are useful for cancer diagnosis and therapy are disclosed.
    Type: Application
    Filed: June 30, 2017
    Publication date: November 16, 2017
    Inventors: Arul M. Chinnaiyan, Scott Tomlins, Saravana Mohan Dhanasekaran
  • MIPOL1-ETV1 gene rearrangements
    Patent number: 9719143
    Abstract: Compositions and methods associated with recurrent MIPOL1-ETV1 genetic rearrangements that are useful for cancer diagnosis and therapy are disclosed.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: August 1, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul M. Chinnaiyan, Scott Tomlins, Saravana Mohan Dhanasekaran
  • Using phage epitopes to profile the immune response
    Patent number: 9658231
    Abstract: The present disclosure provides compositions and methods for using one or more polypeptide probes to profile an immune response. The polypeptide probe can be used to detect one or more antibodies from a sample. Furthermore, the present disclosure provides methods and compositions for characterizing a cancer based on the detection of one or more antibodies, such as autoantibodies.
    Type: Grant
    Filed: August 10, 2015
    Date of Patent: May 23, 2017
    Assignees: The Regents of the University of Michigan, Armune Biosciences, Inc.
    Inventors: Arul M. Chinnaiyan, Xiaoju Wang, Alex Tsodikov, Jeanne Ohrnberger
  • PHAGE MICROARRAY PROFILING OF THE HUMORAL RESPONSE TO DISEASE
    Publication number: 20160264959
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods and compositions for phage microarray profiling of cancer (e.g., prostate, lung, or breast cancer). The present invention further provides novel markers useful for the diagnosis, characterization, and treatment of cancers.
    Type: Application
    Filed: January 12, 2016
    Publication date: September 15, 2016
    Inventors: Arul M. Chinnaiyan, Xiaoju Wang
  • MIPOL1-ETV1 GENE REARRANGEMENTS
    Publication number: 20160208343
    Abstract: Compositions and methods associated with recurrent MIPOL1-ETV1 genetic rearrangements that are useful for cancer diagnosis and therapy are disclosed.
    Type: Application
    Filed: March 30, 2016
    Publication date: July 21, 2016
    Inventors: Arul M. Chinnaiyan, Scott Tomlins, Saravana Mohan Dhanasekaran
  • MIPOL1-ETV1 gene rearrangements
    Patent number: 9303291
    Abstract: Compositions and methods associated with recurrent MIPOL1-ETV1 genetic rearrangements that are useful for cancer diagnosis and therapy are disclosed.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: April 5, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul M. Chinnaiyan, Scott Tomlins, Saravana Mohan Dhanasekaran
  • USING PHAGE EPITOPES TO PROFILE THE IMMUNE RESPONSE
    Publication number: 20160041174
    Abstract: The present disclosure provides compositions and methods for using one or more polypeptide probes to profile an immune response. The polypeptide probe can be used to detect one or more antibodies from a sample. Furthermore, the present disclosure provides methods and compositions for characterizing a cancer based on the detection of one or more antibodies, such as autoantibodies.
    Type: Application
    Filed: August 10, 2015
    Publication date: February 11, 2016
    Inventors: Arul M. Chinnaiyan, Xiaoju Wang, Alex Tsodikov, Jeanne Ohrnberger