Patents by Inventor Ashutosh Chilkoti

Ashutosh Chilkoti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030059840
    Abstract: Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of a compound to a particular location within an animal subjects. In general, the bioelastomer is conjugated to a binding compound, which is in turn used to bind a compound of interest. For targeted compound delivery, the bioelastomer is conjugated to the compound to be delivered.
    Type: Application
    Filed: July 31, 2002
    Publication date: March 27, 2003
    Inventor: Ashutosh Chilkoti
  • Publication number: 20030047220
    Abstract: The present invention provides a hybrid material and a method for forming a hybrid material comprising actuator made from a stimuli responsive polymer mounted in a porous framework. The present invention also provides devices employing the actuator of the present invention.
    Type: Application
    Filed: September 11, 2002
    Publication date: March 13, 2003
    Inventors: Gabriel P. Lopez, Ashutosh Chilkoti, Plamen Atanassov, Venkata Goparaju
  • Patent number: 6491061
    Abstract: The present invention provides a hybrid material and a method for forming a hybrid material comprising actuator made from a stimuli responsive polymer mounted in a porous framework. The present invention also provides devices employing the actuator of the present invention.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: December 10, 2002
    Assignee: University of New Mexico
    Inventors: Gabriel Lopez, Ashutosh Chilkoti, Plamen Atanassov, Venkata Goparaju
  • Patent number: 6444254
    Abstract: Functionalized polymer surfaces having reactive moieties thereon are contacted with stamps having ligands adsorbed thereto, the ligands also comprising reactive moieties. The reactive moieties of the functionalized surfaces and the ligands form covalent bonds, thus providing a method of microstamping polymer surfaces directly with ligands such as biological ligands. Using this method, devices such as tissue culture plates with polymer surfaces that are microstamped directly with ligands can be made.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: September 3, 2002
    Assignee: Duke University
    Inventors: Ashutosh Chilkoti, Zhongping Yang
  • Publication number: 20010034050
    Abstract: Genetically-encodable, environmentally-responsive fusion proteins comprising ELP peptides. Such fusion proteins exhibit unique physico-chemical and functional properties that can be modulated as a function of solution environment. The invention also provides methods for purifying the FPs, which take advantage of these unique properties, including high-throughput purification methods that produce high yields (e.g., milligram levels) of purified proteins, thereby yielding sufficient purified product for multiple assays and analyses. The high throughput purification technique is simpler and less expensive than current commercial high throughput purification methods, since it requires only one transfer of purification intermediates to a new multiwell plate.
    Type: Application
    Filed: March 20, 2001
    Publication date: October 25, 2001
    Inventor: Ashutosh Chilkoti