Abstract: A cell population comprising Corin- and/or Lrtm1-positive cells was produced by the following steps (1) and (2), from which Corin positive and/or Lrtm1 positive cells are collected using a substance that binds to Corin and/or a substance that binds to Lrtm1, and dopaminergie neuron progenitor cells are produced by performing suspension culture of the Corin positive and/or Lrtm1 positive cells in a culture solution containing one or more nutritional factors: (1) a step of performing adhesion culture of pluripotent stem cells in a medium for maintaining undifferentiated state containing a Sonic hedgehog (SHH) signal stimulant, and an undifferentiated state-maintaining factor in the absence of feeder cells but in the presence of an extracellular matrix, and (2) a step of culturing the cell population obtained in the step (1) in a culture solution containing one or more differentiation-inducing factors.

Abstract: The present invention provides a compound represented by chemical formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same.

Abstract: The lid device includes a latch body for a latch receiver provided in an opening forming body, an urging device that urges the latch body to always be in a position of being engaged with the latch receiver, and a switching member that is movably provided on a lid lower and that disengages the latch body and the latch receiver in a forward portion. A lid upper is combined with the lid lower so as to be able to slidably move in a direction orthogonal to the axial direction of the rotation center axis of the lid cover. Also provided is a linking member that links the lid upper and the lid lower so that the switching member is moved to the forward position when the lid upper is movably operated toward the rotation center axis of the lid lower.

Abstract: Provided are a storage device and a cover member for the storage device with which a gap that exposes an internal structure can be shielded without degrading design. In the cover body for the storage device, a gap is formed between an end section of a shutter and upper left and right surface decoration sections, the end section of the shutter on the gap side is formed by a shielding member, and the shielding member extends toward between the upper left or right surface decoration section and a frame-side rail and reaches a lower side of each of the upper left and right surface decoration sections.

Abstract: The resin molded article is molded by using an electrode sheet as an insert in a state where one surface of the electrode sheet is closely attached to an inner surface which serves as the inner side of the operation surface. The electrode sheet is formed by using, as a base material, a thermoplastic synthetic resin sheet which outputs an electrical signal according to the amount of change of electrostatic capacitance generated by a contact operation with respect to the operation surface. At least a whole or a part of the inner surface is formed in a three-dimensionally curved surface, and a passage is formed in the electrode sheet so as to allow a molten resin following in through a gate formed in a die which comes into contact with the other surface of the electrode sheet during molding to pass toward one surface side of the electrode sheet.

Abstract: The display device includes a display, a resin member, and a transparent layer. The display includes a first surface on which an image is displayed, a second surface located oppositely to the first surface, and a side surface extending from the first surface to reach the second surface. The resin member includes an inner wall surface at least partially opposed to the side surface of the display, a first surface connected to the inner wall surface and located on the same side as the first surface of the display, and a second surface connected to the inner wall surface and located on the same side as the second surface of the display. The transparent layer includes a second surface spreading in contact with the first surface of the display and the first surface of the resin member, and a first surface located oppositely to the second surface.

Abstract: A photoacoustic imaging device includes an excitation light irradiation unit that irradiates the same position of a specimen with two or more beams of pulsed excitation light separated by an irradiation time interval, a detector that detects an acoustic wave generated at the position irradiated with the excitation light by the excitation light irradiation unit, a generator that generates an image of the specimen based on the detected acoustic wave, and a controller that controls the irradiation time interval, the acoustic wave generated with a single beam of pulsed excitation light has multiple positive peaks that periodically occur, and the controller controls the irradiation time interval into a timing at which a second positive peak of the acoustic wave generated with the preceding excitation light is superimposed on a first positive peak of the acoustic wave generated with the subsequent excitation light.

Abstract: A photoacoustic imaging device includes an irradiator irradiating a specimen with excitation light, a detection unit detecting an acoustic wave at an irradiated position, a propagation body including a bag-shaped body including a film deforming in conformity with a surface shape of the specimen, an interior of the bag-shaped body being filled with an acoustic wave propagation medium, and a processor including hardware and configured to generate an image based on the detected acoustic wave, wherein the propagation body is disposed between the detection unit and the specimen, without interposing any air layers, and moves along with relative movement of the detection unit and the specimen, the detection unit includes an optics collecting the acoustic wave, the propagation body is attached to the optics, and a difference of refractive indexes between the optics and the propagation body is smaller than a difference of refractive indexes between the optics and air.

Abstract: A point-spread-function measurement device includes: a scanner that scans two illumination light beams emitted from a light source; an illumination optical system that radiates the two illumination light beams scanned by the scanner onto a sample; a relative-position adjustor that changes a relative irradiation position, in the sample, between the two illumination light beams radiated by the illumination optical system; a detection optical system that detects signal light generated at an overlapping position, in the sample, of the illumination light beams radiated by the illumination optical system; and a calculator that calculates a point spread function based on the signal light detected by the detection optical system and the relative irradiation position between the two illumination light beams when the signal light is detected.

Abstract: An image acquisition method in which a pulsed illumination beam emitted from a light source is scanned while being focused at a sample, signal light generated as a result of a non-linear optical process at each scanning position is detected, and an image of the sample is generated on a basis of the detected signal light, the image acquisition method including: acquiring a mixed image, which includes in-focus signal light generated at a focal position of the illumination beam in the sample and which also includes out-of-focus signal light; acquiring an image of the out-of-focus signal light on a basis of a plurality of mixed images having mutually different intensities of the out-of-focus signal light; and acquiring an image of the in-focus signal light by subtracting the image of the out-of-focus signal light acquired, from the mixed image acquired.

Abstract: The resin molded article is molded by using an electrode sheet as an insert in a state where one surface of the electrode sheet is closely attached to an inner surface which serves as the inner side of the operation surface. The electrode sheet is formed by using, as a base material, a thermoplastic synthetic resin sheet which outputs an electrical signal according to the amount of change of electrostatic capacitance generated by a contact operation with respect to the operation surface. At least a whole or a part of the inner surface is formed in a three-dimensionally curved surface, and a passage is formed in the electrode sheet so as to allow a molten resin following in through a gate formed in a die which comes into contact with the other surface of the electrode sheet during molding to pass toward one surface side of the electrode sheet.

Abstract: To provide a vehicle illumination device that achieves good design and that appropriately emits light in a sequence of operations for charging. A vehicle illumination device 1 includes: first light emitting portions 21a and 21b disposed in the vicinity of a boundary portion 4 between a body 2 and a lid 14 via notched portions 18a and 18b formed at upper and lower edges of the lid 14; and second light emitting portions 22a and 22b disposed inside the lid 14. When the lid 14 is unlocked in operation to unlock the lid 14, the first light emitting portions 21a and 21b are turned on. When the lid 14 is depressed in operation to open the lid 14, the first light emitting portions 21a and 21b are turned off. When the lid 14 is opened, the second light emitting portions 22a and 22b are turned on to illuminate power supply ports 11 and 12.

Abstract: There are provided a device and a method for more appropriate evaluation of a chemical substance. The device for the evaluation of the chemical substance includes a first compartment, and a second compartment that communicates with the first compartment and is separated from the first compartment by a partition wall.

Abstract: A lens system is configured to form an image of an object on an imaging surface of an image sensor. A branching optical system is configured such that an image-forming light flux in the lens system is split and propagated into a plurality of optical paths having different optical path lengths and such that the principal rays of a plurality of image-forming light fluxes obtained after the splitting are incident on a predetermined region of the image sensor.

Abstract: To provide a vehicle illumination device that achieves good design and that appropriately emits light in a sequence of operations for charging. A vehicle illumination device 1 includes: first light emitting portions 21a and 21b disposed in the vicinity of a boundary portion 4 between a body 2 and a lid 14 via notched portions 18a and 18b formed at upper and lower edges of the lid 14; and second light emitting portions 22a and 22b disposed inside the lid 14. When the lid 14 is unlocked in operation to unlock the lid 14, the first light emitting portions 21a and 21b are turned on. When the lid 14 is depressed in operation to open the lid 14, the first light emitting portions 21a and 21b are turned off. When the lid 14 is opened, the second light emitting portions 22a and 22b are turned on to illuminate power supply ports 11 and 12.

Abstract: An observation assistance device of the present invention includes: an information storage unit that stores sample state information showing a sample state change, a type of sample, a type of fluorescent substance, and an observation condition in fluorescence observation performed on a predetermined sample, and under a predetermined observation condition; an input unit via which inputs the type of sample to be observed and the type of fluorescent substance to be used; an assistance-display generating unit that reads sample state information and an observation condition of fluorescence observation performed on the same type of sample as the type of sample input, using the same type of fluorescent substance as the type of fluorescent substance, and generates an assistance display showing the sample state information in relation to the two or more parameters included in the observation condition; and a display unit that displays the generated assistance display.

Abstract: An in-vehicle storage unit that can store an item to be stored in a vehicle, and includes: a storing portion that stores an item to be stored; an opening formed in the storing portion; a lid that is formed on the opening, and can be opened and closed; and a touch sensor panel that is formed in a surface of the lid, and can sense a touch operation by an operator. The touch sensor panel displays an operation icon on the touch sensor panel, in accordance with a sensing signal of the touch operation.

Abstract: A microscope system includes an objective lens that focuses, on a specimen, illumination light produced by a light source. An illumination-area switching mechanism is disposed between the objective lens and the specimen and switches an illumination area irradiated with the illumination light focused by the objective lens among a plurality of illumination areas on the specimen that are located outside an objective optical axis of the objective lens. An inner focus lens is disposed on the objective optical axis between the light source and the objective lens and changes a focus position of the objective lens in a direction along the objective optical axis.

Abstract: An observation assistance device of the present invention includes: an information storage unit that stores sample state information showing a sample state change, a type of sample, a type of fluorescent substance, and an observation condition in fluorescence observation performed on a predetermined sample, and under a predetermined observation condition; an input unit via which inputs the type of sample to be observed and the type of fluorescent substance to be used; an assistance-display generating unit that reads sample state information and an observation condition of fluorescence observation performed on the same type of sample as the type of sample input, using the same type of fluorescent substance as the type of fluorescent substance, and generates an assistance display showing the sample state information in relation to the two or more parameters included in the observation condition; and a display unit that displays the generated assistance display.

Abstract: Provided is a microscope provided with: a scanner that scans an excitation beam coming from a light source; an objective optical system that focuses the scanned excitation beam onto a sample and that collects fluorescence generated at individual scanning positions in the sample; a detector that detects the collected fluorescence; a light blocking member that is disposed between the detector and the system and that partially blocks the collected fluorescence; a switching portion that switches the positional relationship between the member and a light-focusing point of the excitation beam in the sample between an optically conjugate positional relationship, in which an in-focus fluorescence generated at the light-focusing point passes through the member, and a non-conjugate positional relationship, in which the in-focus fluorescence is blocked by the member; and a computing portion that computes a difference between fluorescence signals acquired by the detector in the two positional relationships.