Patents by Inventor Avak Kahvejian

Avak Kahvejian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF
    Publication number: 20240122959
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of circular polyribonucleotides and uses thereof.
    Type: Application
    Filed: December 18, 2023
    Publication date: April 18, 2024
    Inventors: Avak KAHVEJIAN, Alexandra Sophie De Boer, Nicholas McCartney Plugis, Erica Gabrielle Weinstein, Sebastian Trousil, Morag Helen Stewart, Ki Young Paek, Catherine Cifuentes-Rojas
  • ADIPOGENIC CELL COMPOSITIONS AND METHODS
    Publication number: 20240009249
    Abstract: Disclosed herein are compositions comprising adipogenic cells that are useful for the treatment, prevention, or amelioration of diseases or disorders.
    Type: Application
    Filed: November 24, 2021
    Publication date: January 11, 2024
    Inventors: Alexandra Sophie DE BOER, Le Phuan Lizzie NGO, Avak KAHVEJIAN, Jordan LEWANDOWSKI
  • IMMUNOGENIC COMPOSITIONS AND USES THEREOF
    Publication number: 20240009298
    Abstract: This disclosure provides compositions, pharmaceutical preparations, and uses of polyribonucleotides encoding one or more immunogenic polypeptides. In particular, this disclosure features circular polyribonucleotide encoding one or more immunogenic polypeptides.
    Type: Application
    Filed: September 3, 2021
    Publication date: January 11, 2024
    Inventors: Avak KAHVEJIAN, Alexandra Sophie DE BOER, Yann Paul Guy Régis ECHELARD, Nicholas McCartney PLUGIS, Erica Gabrielle WEINSTEIN, Jennifer A. NELSON
  • Compositions comprising circular polyribonucleotides and uses thereof
    Patent number: 11844759
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of circular polyribonucleotides and uses thereof.
    Type: Grant
    Filed: November 16, 2022
    Date of Patent: December 19, 2023
    Assignee: Flagship Pioneering Innovations VI, LLC
    Inventors: Avak Kahvejian, Alexandra Sophie De Boer, Nicholas McCartney Plugis, Erica Gabrielle Weinstein, Sebastian Trousil, Morag Helen Stewart, Ki Young Paek, Catherine Cifuentes-Rojas
  • COMPOSITIONS COMPRISING LINEAR POLYRIBONUCLEOTIDES FOR PROTEIN MODULATION AND USES THEREOF
    Publication number: 20230340451
    Abstract: This invention relates to compositions comprising linear polyribonucleotides and uses thereof.
    Type: Application
    Filed: January 29, 2021
    Publication date: October 26, 2023
    Inventors: Avak KAHVEJIAN, Alexandra Sophie DE BOER
  • Compositions and Methods Related to Multimodal Therapeutic Cell Systems for Cancer Indications
    Publication number: 20230293588
    Abstract: The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
    Type: Application
    Filed: January 25, 2023
    Publication date: September 21, 2023
    Applicant: Rubius Therapeutics, Inc.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, Robert J. Deans, Tiffany F. Chen, John Round, Noubar B. Afeyan, Torben Straight Nissen, Nathan J. Dowden, Tom Wickham, Sivan Elloul
  • COMPOSITIONS COMPRISING CURONS AND USES THEREOF
    Publication number: 20230279423
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of curons and uses thereof.
    Type: Application
    Filed: July 15, 2022
    Publication date: September 7, 2023
    Inventors: Avak Kahvejian, Erica Gabrielle Weinstein, Nicholas McCartney Plugis, Kevin James Lebo, Fernando Martin Diaz, Dhananjay Maniklal Nawandar
  • METHODS OF IDENTIFYING AND CHARACTERIZING ANELLOVIRUSES AND USES THEREOF
    Publication number: 20230227849
    Abstract: This invention relates generally to compositions and methods for administering an anellovector (e.g., a synthetic anellovector) that can be used as a delivery vehicle, e.g., for delivering genetic material, for delivering an effector, e.g., a payload, or for delivering a therapeutic agent or a therapeutic effector to a eukaryotic cell (e.g., a human cell or a human tissue). Also provided are methods for amplifying circular nucleic acids comprising Anellovirus sequences.
    Type: Application
    Filed: June 17, 2021
    Publication date: July 20, 2023
    Inventors: Avak Kahvejian, Erica Gabrielle Weinstein, Roger Joseph Hajjar, Nathan Lawrence Yozwiak, Simon Delagrave, Yann Paul Guy Régis Echelard, Simeon Ungerleider Springer, Cesar A. Arze, Kristian Graugaard Andersen
  • COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF
    Publication number: 20230201241
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of circular polyribonucleotides and uses thereof.
    Type: Application
    Filed: November 16, 2022
    Publication date: June 29, 2023
    Inventors: Avak Kahvejian, Alexandra Sophie De Boer, Nicholas McCartney Plugis, Erica Gabrielle Weinstein, Sebastian Trousil, Morag Helen Stewart, Ki Young Paek, Catherine Cifuentes-Rojas
  • COMPOSITIONS AND METHODS FOR PRODUCING HUMAN POLYCLONAL ANTIBODIES
    Publication number: 20230203192
    Abstract: The disclosure provides compositions and methods for generating polyclonal antibodies, for example, using circular polyribonucleotides and non-human animals having humanized immune systems.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 29, 2023
    Inventors: Alexandra Sophie DE BOER, Avak KAHVEJIAN, Frances Marion Nicole ANASTASSACOS, Jennifer A. NELSON, Nicholas McCartney PLUGIS, Roger Joseph HAJJAR, Yann Paul Guy Régis ECHELARD
  • METHODS FOR MODULATING INTESTINE CELLS OR TISSUE FUNCTION
    Publication number: 20230203158
    Abstract: Macromolecule compositions and related methods that effect targeted delivery of therapeutic agents to effector targets in a desired cell, tissue and/or organ of interest while minimizing or avoiding undesirable delivery to other cells, tissues or organs are provided. Compositions and methods related to macromolecules, such as an ANDbody™, that include an effector target binding domain specific for an effector target, and an address binding domain specific for an address target are described.
    Type: Application
    Filed: November 16, 2022
    Publication date: June 29, 2023
    Inventors: Adrienne Marie ROTHSCHILDS, Nicholas McCartney Plugis, Charlotte Marie Nicod, Stephen Marshall, Avak Kahvejian, Yann Paul Guy Régis Echelard, Noubar Boghos Afeyan, Raffi Afeyan, Scott Moore Carlson, Vivek Kohar, Daniel Blom
  • IMMUNOGENIC COMPOSITIONS AND USES THEREOF
    Publication number: 20230193311
    Abstract: This disclosure provides compositions, pharmaceutical preparations, and uses of polyribonucleotides encoding one or more immunogenic polypeptides. In particular, this disclosure features circular polyribonucleotide encoding one or more immunogenic polypeptides.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 22, 2023
    Inventors: Avak KAHVEJIAN, Alexandra Sophie DE BOER, Yann Paul Guy Régis ECHELARD, Nicholas McCartney PLUGIS, Erica Gabrielle WEINSTEIN, Jennifer A. NELSON
  • COMPOSITIONS FOR TRANSLATION AND METHODS OF USE THEREOF
    Publication number: 20230181620
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of polyribonucleotides and circular polyribonucleotides and uses thereof.
    Type: Application
    Filed: January 29, 2021
    Publication date: June 15, 2023
    Inventors: Avak KAHVEJIAN, Alexandra Sophie DE BOER, Nicholas McCartney PLUGIS, Ki Young PAEK
  • CORONAVIRUS ANTIGEN COMPOSITIONS AND THEIR USES
    Publication number: 20230181722
    Abstract: The disclosure provides compositions and methods comprising circular polyribonucleotides comprising a sequence encoding a coronavirus antigen, and compositions and methods comprising linear polyribonucleotides comprising a sequence encoding a coronavirus antigen. Compositions and methods are provided that are related to generating polyclonal antibodies, for example, using the disclosed circular polyribonucleotides or the disclosed linear polyribonucleotides.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 15, 2023
    Inventors: Avak KAHVEJIAN, Alexandra Sophie DE BOER, Yann Paul Guy Régis ECHELARD, Nicholas McCartney PLUGIS, Roger Joseph HAJJAR, Michael Donato MELFI, Jennifer A. NELSON
  • DELIVERY OF COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES
    Publication number: 20230104113
    Abstract: This invention relates generally to delivery of circular polyribonucleotides and compositions thereof.
    Type: Application
    Filed: January 29, 2021
    Publication date: April 6, 2023
    Inventors: Avak KAHVEJIAN, Nicholas McCartney PLUGIS, Alexandra Sophie DE BOER, Erica Gabrielle WEINSTEIN, Catherine CIFUENTES-ROJAS
  • COMPOSITIONS COMPRISING MODIFIED CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF
    Publication number: 20230072532
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of modified circular polyribonucleotides and uses thereof.
    Type: Application
    Filed: March 25, 2020
    Publication date: March 9, 2023
    Inventors: Avak KAHVEJIAN, Nicholas McCartney PLUGIS, Alexandra Sophie DE BOER, Catherine CIFUENTES-ROJAS, Ki Young PAEK
  • COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF
    Publication number: 20230070937
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of circular polyribonucleotides and uses thereof.
    Type: Application
    Filed: August 30, 2022
    Publication date: March 9, 2023
    Inventors: Avak Kahvejian, Alexandra Sophie De Boer, Nicholas McCartney Plugis, Erica Gabrielle Weinstein, Sebastian Trousil, Morag Helen Stewart, Ki Young Paek, Catherine Cifuentes-Rojas
  • METHODS OF DOSING CIRCULAR POLYRIBONUCLEOTIDES
    Publication number: 20230061936
    Abstract: This invention relates generally to methods of dosing pharmaceutical compositions and preparations of circular polyribonucleotides thereof.
    Type: Application
    Filed: October 31, 2022
    Publication date: March 2, 2023
    Inventors: Avak KAHVEJIAN, Alexandra Sophie DE BOER, Nicholas McCartney PLUGIS
  • ANELLOSOMES FOR DELIVERING SECRETED THERAPEUTIC MODALITIES
    Publication number: 20230048858
    Abstract: This invention relates generally to anellosomes and compositions and uses thereof.
    Type: Application
    Filed: December 12, 2019
    Publication date: February 16, 2023
    Inventors: Erica Gabrielle Weinstein, Avak Kahvejian, Simon Delagrave, Nathan Lawrence Yozwiak, Kevin James Lebo, Fernando Martin Diaz, Dhananjay Maniklal Nawandar, Ryan D. Tedstone, Jared David Pitts
  • Methods and compositions for immunomodulation
    Patent number: 11576934
    Abstract: Provided are cells containing exogenous antigen and uses thereof.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: February 14, 2023
    Assignee: Rubius Therapeutics, Inc.
    Inventors: Jordi Mata-Fink, John Round, Noubar B. Afeyan, Avak Kahvejian