Patents by Inventor Avak Kahvejian

Avak Kahvejian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ERYTHROID CELLS COMPRISING LYSINE OXIDASE
    Publication number: 20190309261
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: June 4, 2019
    Publication date: October 10, 2019
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF
    Publication number: 20190307785
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of circular polyribonucleotides and uses thereof.
    Type: Application
    Filed: June 11, 2019
    Publication date: October 10, 2019
    Inventors: Morag Helen STEWART, Catherine CIFUENTES-ROJAS, Ki Young PAEK, Avak KAHVEJIAN, Nicholas McCartney PLUGIS, Alexandra Sophie DE BOER, Erica Gabrielle WEINSTEIN, Sebastian TROUSIL
  • ERYTHROID CELLS COMPRISING SERINE DEHYDRATASE
    Publication number: 20190309262
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: June 4, 2019
    Publication date: October 10, 2019
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • SYNTHETIC MEMBRANE-RECEIVER COMPLEXES
    Publication number: 20190264177
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: May 10, 2019
    Publication date: August 29, 2019
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • METHODS AND COMPOSITIONS FOR IMMUNOMODULATION
    Publication number: 20190247440
    Abstract: Provided are cells containing exogenous antigen and uses thereof.
    Type: Application
    Filed: April 12, 2019
    Publication date: August 15, 2019
    Inventors: Jordi Mata-Fink, John Round, Noubar B. Afeyan, Avak Kahvejian
  • NEUROMODULATING COMPOSITIONS AND RELATED THERAPEUTIC METHODS FOR THE TREATMENT OF CANCER BY MODULATING AN ANTI-CANCER IMMUNE RESPONSE
    Publication number: 20190240293
    Abstract: Described herein are methods for treating a subject having or at risk of developing cancer administering a neuromodulating agent.
    Type: Application
    Filed: July 25, 2017
    Publication date: August 8, 2019
    Inventors: Erica WEINSTEIN, Jordi MATA-FINK, Avak KAHVEJIAN, Noubar B. AFEYAN, Laura Kristina JEANBART, Alexandra LANTERMANN, Jonathan Barry HUROV, Manuel Andreas FANKHAUSER, Chengyi J. SHU, Eric Franklin ZHU
  • METHODS AND COMPOSITIONS FOR TREATING INFLAMMATORY OR AUTOIMMUNE DISEASES OR CONDITIONS USING CALCITONIN RECEPTOR ACTIVATORS
    Publication number: 20190233527
    Abstract: The present invention provides methods for treating inflammatory or autoimmune disease using calcitonin receptor activators, such as calcitonin receptor activating antibodies, among others. The invention also features compositions containing calcitonin receptor activators, methods of diagnosing patients with calcitonin receptor-associated inflammatory or autoimmune disease, and methods of predicting the response of an inflammatory or autoimmune disease or condition in a subject to treatment with calcitonin receptor activators.
    Type: Application
    Filed: September 24, 2018
    Publication date: August 1, 2019
    Inventors: Avak KAHVEJIAN, Jordi MATA-FINK, Jonathan Barry HUROV, Chengyi Jenny SHU, George Huck NEUBAUER, Manuel Andreas FANKHAUSER, Julian Alexander STANLEY
  • COMPOSITIONS COMPRISING CURONS AND USES THEREOF
    Publication number: 20190211361
    Abstract: This invention relates generally to pharmaceutical compositions and preparations of curons and uses thereof.
    Type: Application
    Filed: March 27, 2019
    Publication date: July 11, 2019
    Inventors: Avak Kahvejian, Erica Gabrielle Weinstein, Nicholas McCartney Plugis, Kevin James Lebo, Fernando Martin Diaz, Dhananjay Maniklal Nawandar
  • Synthetic membrane-receiver complexes
    Patent number: 10344263
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: July 9, 2019
    Assignee: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • GENE EDITING AND TARGETED TRANSCRIPTIONAL MODULATION FOR ENGINEERING ERYTHROID CELLS
    Publication number: 20190201548
    Abstract: The disclosure provides, e.g., modified enucleated erythroid cells having increased or decreased levels of particular endogenous proteins. For example, CD47-negative enucleated erythroid cells may be used to induce tolerance to an exogenous antigen.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 4, 2019
    Inventors: Avak Kahvejian, Jordi Mata-Fink, Billy Law
  • Synthetic membrane-receiver complexes
    Patent number: 10329531
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: June 25, 2019
    Assignee: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • COMPOSITIONS AND METHODS RELATED TO THERAPEUTIC CELL SYSTEMS EXPRESSING EXOGENOUS RNA
    Publication number: 20190161730
    Abstract: The invention includes compositions and methods related to erythroid cells comprising exogenous RNA encoding a protein. The exogenous RNA can comprise a heterologous untranslated region comprising a regulatory element. Alternatively or in combination, the exogenous RNA can comprise chemical modifications.
    Type: Application
    Filed: July 7, 2017
    Publication date: May 30, 2019
    Inventors: Avak Kahvejian, Jordi Mata-Fink, Robert J. Deans, Omid Harandi, Urjeet Khanwalkar, Sneha Hariharan
  • Synthetic membrane-receiver complexes
    Patent number: 10301594
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: May 28, 2019
    Assignee: RUBIUS THERAPEUTICS, INC
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Synthetic membrane-receiver complexes
    Patent number: 10301593
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: May 28, 2019
    Assignee: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • SYNTHETIC MEMBRANE-RECEIVER COMPLEXES
    Publication number: 20190144827
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 16, 2019
    Applicant: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • Synthetic membrane-receiver complexes
    Patent number: 10253296
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: April 9, 2019
    Assignee: RUBIUS THERAPEUTICS, INC.
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan
  • COMPOSITIONS AND METHODS RELATED TO MULTIMODAL THERAPEUTIC CELL SYSTEMS FOR CANCER INDICATIONS
    Publication number: 20190083540
    Abstract: The invention includes compositions and methods related to multimodal therapies, e.g., for treating a cancer. A multimodal therapy described herein provides and/or administers a plurality of agents that function in a coordinated manner to provide a therapeutic benefit to a subject in need thereof, e.g., a subject having a cancer.
    Type: Application
    Filed: December 3, 2018
    Publication date: March 21, 2019
    Inventors: Avak Kahvejian, Jordi Mata-Fink, Robert J. Deans, Tiffany F. Chen, John Round, Noubar B. Afeyan, Torben Straight Nissen, Nathan Dowden, Tom Wickham, Sivan Elloul
  • LIPID NANOPARTICLE METHODS AND COMPOSITIONS FOR PRODUCING ENGINEERED ERYTHROID CELLS
    Publication number: 20190062788
    Abstract: Carriers such as lipid nanoparticles are useful for delivering payloads (such as RNA, DNA, proteins, or small molecules) to cells such as erythroid cells. This disclosure provides improved carriers that comprise a targeting agent that binds a cell surface receptor. In some embodiments, the cell surface receptor is one that undergoes a high rate of endocytosis.
    Type: Application
    Filed: August 21, 2018
    Publication date: February 28, 2019
    Inventors: Omid Harandi, Avak Kahvejian
  • METHODS AND COMPOSITIONS FOR IMMUNOMODULATION
    Publication number: 20180271910
    Abstract: Provided are cells containing exogenous antigen and uses thereof.
    Type: Application
    Filed: March 5, 2018
    Publication date: September 27, 2018
    Inventors: Jordi Mata-Fink, John Round, Noubar B. Afeyan, Avak Kahvejian
  • SYNTHETIC MEMBRANE-RECEIVER COMPLEXES
    Publication number: 20180265847
    Abstract: Compositions comprising synthetic membrane-receiver complexes, methods of generating synthetic membrane-receiver complexes, and methods of treating or preventing diseases, disorders or conditions therewith.
    Type: Application
    Filed: March 29, 2018
    Publication date: September 20, 2018
    Inventors: Avak Kahvejian, Jordi Mata-Fink, John Round, David Arthur Berry, Noubar B. Afeyan