Abstract: Systems and methods of maternal and fetal monitoring include acquiring ultrasound physiological data with an ultrasound transducer. A plurality of electrodes acquire biopotential physiological data from the skin of a patient. A controller receives the ultrasound and biopotential physiological data and calculates fetal heart rate (fHR) values, maternal heart rate (mHR) values, and uterine activity (UA) values from the ultrasound and biopotential physiological data.

Abstract: An ultrasound system includes a transducer array including a flexible substrate, ultrasound transducer elements disposed on the flexible substrate and configured to transmit and acquire ultrasound signals that propagate in a body of a patient, and strain sensors coupled to or integrated into the flexible substrate and configured to measure a strain in the flexible substrate generated by flexing the flexible substrate. The ultrasound system also includes a processor coupled to the ultrasound transducer elements and the strain sensors, wherein the processor is configured to process the signals acquired by the ultrasound transducer elements based at least in part on the strain measured by the strain sensors.

Abstract: Apparatus and methods for a prosthetic heart valve are provided. The apparatus may include a prosthetic heart-valve fitting. The fitting may be seated in a valve annulus of the heart. The fitting may be a fitting that does not include a tissue-penetrating anchor. The fitting may be a fitting that does not include a tissue-penetrating barb. The apparatus may include a brace. The brace may be urged by an atrial tissue of the heart to maintain a position of the fitting in the annulus.

Abstract: Embodiments of delivery systems, devices and methods for delivering a prosthetic heart valve device to a heart chamber for expanded implementation are disclosed. More specifically, methods, systems and devices are disclosed for delivering a self-expanding prosthetic mitral valve device to the left atrium, with no engagement of the left ventricle, the native mitral valve leaflets or the annular tissue downstream of the upper annular surface during delivery, and in some embodiments with no engagement of the ventricle, mitral valve leaflets and/or annular tissue located downstream of the upper annular surface by the delivered, positioned and expanded prosthetic mitral valve device.

Abstract: Systems, methods, and software for analyzing data logs. In one embodiment, a method comprises collecting a plurality of the data logs from log-generating elements, converting the data logs into log images, performing image analysis on a plurality of the log images to extract insights, and generating an output based on the insights.

Abstract: The present disclosure generally relates to logging user activities during a subset of a recurring time period. In some embodiments, based on received physiological data, a computer system enables logging of one or more user activities to be performed during a subset of a recurring time period. In some embodiments, based on performance of the one or more user activities during a subset of a recurring time period, a computer system enables logging of one or more user activities to be performed during a subset of a recurring time period for a predetermined period of time.

Abstract: In a segmented ball valve for low noise and anti-cavitation applications, a replaceable cartridge is fixed inside and retained by stem and end post. The segment has a machined cylindrical bore with a slide-fit noise cartridge, enabling field replaceability with minor effort & without need of welding or fasteners. The replaceable cartridge also enables use of a fully cylindrical cartridge with greater pressure reduction stages compared to welded-on noise plates on the segment. The segment has a flattened front face resulting in lower Fd enabled by dual flow path in lower openings values thereby attaining higher noise attenuation where the cartridge is not required. The curved plates of the low noise and anti-cavitation cartridge enable: expanding flow resulting in non-impinging jet streams thereby achieving higher noise attenuation in one direction; and converging flow in the opposite direction resulting in reduction of flow energy, and the potential for cavitation for liquids.

Abstract: A device and method for predictably and controlling the collapsing of a collapsible and expandable stent for subsequent translation through a delivery sheath lumen to an anatomical target such as a heart valve or intravascular location for expansion and implantation. The loading device defines in inner lumen comprising a successively decreasing, from the proximal to the distal direction, inner diameter to a region of constant inner diameter wherein the stent is in a collapsed configuration. The device and method may provide for an at least partially collapsed configuration of the stent that may be further collapsed as a part of the implantation procedure and may comprise a stent that is pre-loaded for future use.

Abstract: A collapsible and expandable prosthetic heart valve stent is provided that may be adapted to provide a one-way blood flow therethrough that targets blood flow at the posterior lateral side of a ventricle to enable a natural blood flow to persist post-implant.

Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, the stent being formed of a plurality of struts forming cells. A valve assembly is disposed within the stent, the valve assembly including a plurality of leaflets and a cuff. At least one runner is coupled to a cell and configured to transition from a first configuration to a second configuration when the stent moves from the collapsed condition to the expanded condition.

Abstract: A maternal and fetal monitoring system includes a detection probe configured to conduct physiological measurements on a maternal abdomen, the detection probe comprising a probe housing configured to be attached to the maternal abdomen, and a plurality of electrodes integrated into the probe housing and configured to acquire biopotential physiological data from the maternal abdomen. At least one controller is configured to calculate fetal heart rate (fHR) values, maternal heart rate (mHR) values, and/or uterine activity (UA) values based on both the physiological measurements and the biopotential physiological data, and a graphical display communicatively connected to the controller to receives and visually presents the calculated fHR values, mHR values, and/or UA values.

Abstract: The present disclosure generally relates to logging user activities during a subset of a recurring time period. In some embodiments, based on received physiological data, a computer system enables logging of one or more user activities to be performed during a subset of a recurring time period. In some embodiments, based on performance of the one or more user activities during a subset of a recurring time period, a computer system enables logging of one or more user activities to be performed during a subset of a recurring time period for a predetermined period of time.

Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, the stent being formed of a plurality of struts forming cells. A valve assembly is disposed within the stent, the valve assembly including a plurality of leaflets and a cuff. At least one runner is coupled to a cell and configured to transition from a first configuration to a second configuration when the stent moves from the collapsed condition to the expanded condition.

Abstract: Techniques for determining reliability of a workload migration activity are disclosed. In one embodiment, sub-tasks associated with the workload migration activity may be determined. Further, statistical data associated with an execution of the sub-tasks corresponding to different instances of the workload migration activity may be retrieved. Furthermore, a reliability model may be trained through machine learning using the statistical data to determine reliability of the workload migration activity. Then, the reliability of a new workload migration activity may be determined using the trained reliability model.

Abstract: Loading systems for prosthetic heart valve devices are disclosed. A loading funnel is provided within a watertight interior space that is at least partially filled or fillable with biocompatible fluid. Funnel may have a cylindrical end to which is connected a delivery catheter having a lumen that will receive the collapsed prosthetic heart valve device. An expanded prosthetic heart valve device may be placed within the funnel and pushed or pulled into the funnel which provides a predictable, reliable and repeatable surface for collapsing the prosthetic heart valve device. Ultimately the prosthetic heart valve device is collapsed and translated into the lumen of the delivery catheter for further translation therealong and release into the heart chamber of interest.

Abstract: Loading systems for prosthetic heart valve devices are disclosed. A loading funnel is provided within a watertight interior space that is at least partially filled or fillable with biocompatible fluid. Funnel may have a cylindrical end to which is connected a delivery catheter having a lumen that will receive the collapsed prosthetic heart valve device. An expanded prosthetic heart valve device may be placed within the funnel and pushed or pulled into the funnel which provides a predictable, reliable and repeatable surface for collapsing the prosthetic heart valve device. Ultimately the prosthetic heart valve device is collapsed and translated into the lumen of the delivery catheter for further translation therealong and release into the heart chamber of interest.

Abstract: A device and method for predictably and controlling the collapsing of a collapsible and expandable stent for subsequent translation through a delivery sheath lumen to an anatomical target such as a heart valve or intravascular location for expansion and implantation. The loading device defines in inner lumen comprising a successively decreasing, from the proximal to the distal direction, inner diameter alternating between two sections of decreasing diameter and two sections of constant diameter until reaching the inner diameter of the delivery sheath. A fluid-filled reservoir is provided at the proximal end of the loading device that is configured to provide moisture or wetting for materials associated with or attached to the stent that require moisture retention. Thus, as the stent is being collapsed with the loading device, at least a portion of the stent may be immersed in the fluid reservoir to preserve the subject material.

Abstract: A prosthetic heart valve may include a stent having an inflow end, an outflow end, a collapsed condition, and an expanded condition. The prosthetic valve may also include a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets. The prosthetic valve and/or stent may include features to anchor the prosthetic valve to a native valve annulus and to seal the prosthetic valve with respect to the native valve annulus, such as planar and/or nonplanar annular sealing members coupled to ends of the stent. The stent may include one or more circumferential rows of anchor members or hooks extending radially outwardly from the stent. These hooks may be configured to extend in a particular direction when the stent is in the collapsed condition to facilitate resheathing of the stent if, upon deployment, a user determines the prosthetic heart valve is not positioned optimally.

Abstract: A method comprises the steps of using microcomputer circuitry and logic generating data format providing activation and deactivation of a portable air cooling unit and operating the blower fan at differing speeds optimizing and conserving the rate of expending pre-cooled refrigerant. First, deactivating the unit during periods when cooling is unnecessary. Using sensors, including proximity sensors, for sensing the data format of individuals. The logic upon detecting an individual within the predefined range generates data format activating the chilled air output and deactivating the unit upon not sensing objects. The data format associated with the objects, dimensional aspect of range and operations of the portable air cooling unit are stored in the memory. Additionally, the active coupling of the temperature sensors operates the fan at lower speeds when the outside temperature is within the cooler temperature setting spectrum. Alternatively, switches are provided for operating the portable air cooling units.

Abstract: The present invention provides a prosthetic heart valve device with improved fit and/or apposition between the device frame and left atrial tissue and/or the device base and the annular tissue of the left atrium to improve shifting of the implanted device and/or mitigate paravalvular leakage. The improved fit and/or apposition arises in various embodiments by providing or allowing an asymmetrical frame and/or frame base and/or providing a lower lip to aid in conforming to the asymmetrical shape of the atrium and/or ensure firm positioning therein. An additional benefit of these arrangement(s) is mitigation of paravalvular leakage as a result of improved fit and seal. In certain embodiments, the asymmetry of the frame assists with delivery of the device into the atrium.