Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, the stent being formed of a plurality of struts forming cells. A valve assembly is disposed within the stent, the valve assembly including a plurality of leaflets and a cuff. At least one runner is coupled to a cell and configured to transition from a first configuration to a second configuration when the stent moves from the collapsed condition to the expanded condition.

Abstract: A maternal and fetal monitoring system includes a detection probe configured to conduct physiological measurements on a maternal abdomen, the detection probe comprising a probe housing configured to be attached to the maternal abdomen, and a plurality of electrodes integrated into the probe housing and configured to acquire biopotential physiological data from the maternal abdomen. At least one controller is configured to calculate fetal heart rate (fHR) values, maternal heart rate (mHR) values, and/or uterine activity (UA) values based on both the physiological measurements and the biopotential physiological data, and a graphical display communicatively connected to the controller to receives and visually presents the calculated fHR values, mHR values, and/or UA values.

Abstract: The present disclosure generally relates to logging user activities during a subset of a recurring time period. In some embodiments, based on received physiological data, a computer system enables logging of one or more user activities to be performed during a subset of a recurring time period. In some embodiments, based on performance of the one or more user activities during a subset of a recurring time period, a computer system enables logging of one or more user activities to be performed during a subset of a recurring time period for a predetermined period of time.

Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, the stent being formed of a plurality of struts forming cells. A valve assembly is disposed within the stent, the valve assembly including a plurality of leaflets and a cuff. At least one runner is coupled to a cell and configured to transition from a first configuration to a second configuration when the stent moves from the collapsed condition to the expanded condition.

Abstract: Techniques for determining reliability of a workload migration activity are disclosed. In one embodiment, sub-tasks associated with the workload migration activity may be determined. Further, statistical data associated with an execution of the sub-tasks corresponding to different instances of the workload migration activity may be retrieved. Furthermore, a reliability model may be trained through machine learning using the statistical data to determine reliability of the workload migration activity. Then, the reliability of a new workload migration activity may be determined using the trained reliability model.

Abstract: Loading systems for prosthetic heart valve devices are disclosed. A loading funnel is provided within a watertight interior space that is at least partially filled or fillable with biocompatible fluid. Funnel may have a cylindrical end to which is connected a delivery catheter having a lumen that will receive the collapsed prosthetic heart valve device. An expanded prosthetic heart valve device may be placed within the funnel and pushed or pulled into the funnel which provides a predictable, reliable and repeatable surface for collapsing the prosthetic heart valve device. Ultimately the prosthetic heart valve device is collapsed and translated into the lumen of the delivery catheter for further translation therealong and release into the heart chamber of interest.

Abstract: Loading systems for prosthetic heart valve devices are disclosed. A loading funnel is provided within a watertight interior space that is at least partially filled or fillable with biocompatible fluid. Funnel may have a cylindrical end to which is connected a delivery catheter having a lumen that will receive the collapsed prosthetic heart valve device. An expanded prosthetic heart valve device may be placed within the funnel and pushed or pulled into the funnel which provides a predictable, reliable and repeatable surface for collapsing the prosthetic heart valve device. Ultimately the prosthetic heart valve device is collapsed and translated into the lumen of the delivery catheter for further translation therealong and release into the heart chamber of interest.

Abstract: A device and method for predictably and controlling the collapsing of a collapsible and expandable stent for subsequent translation through a delivery sheath lumen to an anatomical target such as a heart valve or intravascular location for expansion and implantation. The loading device defines in inner lumen comprising a successively decreasing, from the proximal to the distal direction, inner diameter alternating between two sections of decreasing diameter and two sections of constant diameter until reaching the inner diameter of the delivery sheath. A fluid-filled reservoir is provided at the proximal end of the loading device that is configured to provide moisture or wetting for materials associated with or attached to the stent that require moisture retention. Thus, as the stent is being collapsed with the loading device, at least a portion of the stent may be immersed in the fluid reservoir to preserve the subject material.

Abstract: A prosthetic heart valve may include a stent having an inflow end, an outflow end, a collapsed condition, and an expanded condition. The prosthetic valve may also include a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets. The prosthetic valve and/or stent may include features to anchor the prosthetic valve to a native valve annulus and to seal the prosthetic valve with respect to the native valve annulus, such as planar and/or nonplanar annular sealing members coupled to ends of the stent. The stent may include one or more circumferential rows of anchor members or hooks extending radially outwardly from the stent. These hooks may be configured to extend in a particular direction when the stent is in the collapsed condition to facilitate resheathing of the stent if, upon deployment, a user determines the prosthetic heart valve is not positioned optimally.

Abstract: A method comprises the steps of using microcomputer circuitry and logic generating data format providing activation and deactivation of a portable air cooling unit and operating the blower fan at differing speeds optimizing and conserving the rate of expending pre-cooled refrigerant. First, deactivating the unit during periods when cooling is unnecessary. Using sensors, including proximity sensors, for sensing the data format of individuals. The logic upon detecting an individual within the predefined range generates data format activating the chilled air output and deactivating the unit upon not sensing objects. The data format associated with the objects, dimensional aspect of range and operations of the portable air cooling unit are stored in the memory. Additionally, the active coupling of the temperature sensors operates the fan at lower speeds when the outside temperature is within the cooler temperature setting spectrum. Alternatively, switches are provided for operating the portable air cooling units.

Abstract: The present invention provides a prosthetic heart valve device with improved fit and/or apposition between the device frame and left atrial tissue and/or the device base and the annular tissue of the left atrium to improve shifting of the implanted device and/or mitigate paravalvular leakage. The improved fit and/or apposition arises in various embodiments by providing or allowing an asymmetrical frame and/or frame base and/or providing a lower lip to aid in conforming to the asymmetrical shape of the atrium and/or ensure firm positioning therein. An additional benefit of these arrangement(s) is mitigation of paravalvular leakage as a result of improved fit and seal. In certain embodiments, the asymmetry of the frame assists with delivery of the device into the atrium.

Abstract: Techniques for determining reliability of a workload migration activity are disclosed. In one embodiment, sub-tasks associated with the workload migration activity may be determined. Further, statistical data associated with an execution of the sub-tasks corresponding to different instances of the workload migration activity may be retrieved. Furthermore, a reliability model may be trained through machine learning using the statistical data to determine reliability of the workload migration activity. Then, the reliability of a new workload migration activity may be determined using the trained reliability model.

Abstract: A method modifies how content is broadcast based on the tone and format of the content. One or more processors retrieve a set of rules that describe a tone and format for proposed content that is to be broadcast to an intended target, and determine whether the proposed content conforms to the set of rules. In response to determining that the proposed content does not conform to the set of rules, the processor(s) modify how the proposed content is broadcast to the intended target. The processor(s) generate an enriched content of the modified content by applying, to the modified content, content metatags that describe a content of the modified content, and then analyze the enriched content to calculate a trustworthiness index (TI) for the enriched content. The processors further modify how content is broadcast to the intended target based on the TI of the enriched content.

Abstract: A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent extending between a proximal end and a distal end. The stent includes an annulus section adjacent the proximal end and having a first diameter, a plurality of first struts forming cells, and a plurality of second struts connected to the annulus section and forming a plurality of deflecting cells expandable to define a second diameter larger than the first diameter. A valve assembly is disposed within the stent and a cuff is coupled to the stent and covers the plurality of deflecting cells.

Abstract: The invention provides methods, devices and systems for delivering, positioning and/or repositioning an expandable prosthetic heart valve in a patient's heart chamber. At least one non-looped wire and looped wire pair is operatively connected with an expanded prosthetic heart valve that is collapsed within a delivery catheter lumen having its distal end positioned in the subject heart chamber. The collapsed prosthetic heart valve is translated through the delivery catheter lumen to and out of its distal end where the prosthetic heart valve expands to a working configuration. The wire(s) of the non-looped and looped wire pair may be manipulated by pulling proximately or pushing distally to position or reposition the expanded prosthetic stent into position, then released from connection with the positioned stent and withdrawn from the patient.

Abstract: Techniques for determining reliability of a workload migration activity are disclosed. In one embodiment, sub-tasks associated with the workload migration activity may be determined. Further, statistical data associated with an execution of the sub-tasks corresponding to different instances of the workload migration activity may be retrieved. Furthermore, a reliability model may be trained through machine learning using the statistical data to determine reliability of the workload migration activity. Then, the reliability of a new workload migration activity may be determined using the trained reliability model.

Abstract: A method for transferring memory pages to a first and a second page repository identifies pages in a memory sharing operation for transfer to a first page repository and pages in a memory migration operation for transfer to a second page repository. Pages in the memory migration operation may be prepared for transfer prior to transfer of the pages in the memory sharing operation. Transferring pages in the migration operation may remove the need to transfer pages in the memory sharing operation.

Abstract: Systems and methods of maternal and fetal monitoring include acquiring ultrasound physiological data with an ultrasound transducer. A plurality of electrodes acquire biopotential physiological data from the skin of a patient. A controller receives the ultrasound and biopotential physiological data and calculates fetal heart rate (fHR) values, maternal heart rate (mHR) values, and uterine activity (UA) values from the ultrasound and biopotential physiological data.

Abstract: The present disclosure generally relates to logging health-related events and for health-related coaching. In some embodiments, an event is logged by associating an action with a specific time and a user sentiment. In some embodiments, an event challenge, associated with a log entry, is transmitted to an external electronic device.

Abstract: A collapsible and expandable prosthetic heart valve stent is provided and comprising an outer section, a valve support defining a flow channel therethrough, a transition section configured to smoothly transition the outer section to the valve support. The valve support is disposed within an interior defined by the outer section, with the inflow end of the valve support disposed inside the outer section's interior. In some cases, the outflow end of the valve support is at least partially defined by the transition section. The prosthetic leaflets are disposed on the inner surface of the valve support's flow channel and are located at or above the annulus of the heart chamber. A paravalvular leakage mitigation system is attached to the stent to mitigate retrograde blood flow and/or regurgitation.