Patents by Inventor Beatrice Guardiola

Beatrice Guardiola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted heterocyclic compounds
    Patent number: 6602903
    Abstract: The invention relates to compounds of formula (I): and medicinal products containing the same are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: August 5, 2003
    Assignee: Les Laboratories Servier
    Inventors: Gérald Guillaumet, Marie-Claude Viaud, Ahmed Mamai, Isabelle Charton, Pierre Renard, Caroline Bennejean, Béatrice Guardiola, Philippe Daubos
  • Substituted heterocyclic compounds
    Publication number: 20020052400
    Abstract: The invention relates to compounds of formula (I): 1
    Type: Application
    Filed: August 28, 2001
    Publication date: May 2, 2002
    Applicant: ADIR ET COMPAGNIE
    Inventors: Gerald Guillaumet, Marie-Claude Viaud, Ahmed Mamai, Isabelle Charton, Pierre Renard, Caroline Bennejean, Beatrice Guardiola, Philippe Daubos
  • Substituted heterocyclic compounds, method for preparing and compositions containing same
    Patent number: 6313160
    Abstract: The invention relates to compounds of formula (I): wherein: R1, R2 and R3 are as defined in the description, X is as defined in the description, Y represents an oxygen atom, a sulphur atom, a C(H)q group, SO or SO2, n is equal to from 0 to 5, A represents a NR5R6 group, and medicinal products containing the same which are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: November 12, 1999
    Date of Patent: November 6, 2001
    Assignee: Adir et Compagnie
    Inventors: Gérald Guillaumet, Marie-Claude Viaud, Ahmed Mamai, Isabelle Charton, Pierre Renard, Caroline Bennejean, Béatrice Guardiola, Philippe Daubos
  • Heterocyclic compounds
    Patent number: 5919814
    Abstract: The invention relates to compound of general formula (I): ##STR1## wherein: Z represents O or CH.sub.2n is from 0 to 4R, X and Y are as defined in the description, andA represents ##STR2## wherein R.sup.1, R.sup.2, R.sup.6, R.sup.7 and T' are as defined in the description,and medicinal products containing the same are useful in treating or in preventing melatoninergic disorders.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: July 6, 1999
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Isabelle Charton, Ahmed Mamai, Pierre Renard, Bruno Pfeiffer, Philippe Delagrange, Beatrice Guardiola
  • Tricyclic amides
    Patent number: 5849781
    Abstract: The invention relates to a compound selected from these of formula (I): ##STR1## in which R.sub.7, R.sub.8, Y, n and A are as defined in the description, and medicinal product containing the same useful for treating a disorder of the melatoninergic system.
    Type: Grant
    Filed: October 1, 1997
    Date of Patent: December 15, 1998
    Assignee: Adir Et Compagnie
    Inventors: Michel Langlois, Monique Mathe-Allainmat, Philippe Delagrange, Pierre Renard, Beatrice Guardiola
  • Alkylated (hetero) cyclic compounds
    Patent number: 5780512
    Abstract: The invention relates to a compounds selected from these of formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description, and a medicinal product containing the same useful for treating a melatoninergic disorder.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: July 14, 1998
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Eric Fourmaintraux, Patrick Depreux, Philippe Delagrange, Pierre Renard, Beatrice Guardiola-Lemaitre
  • Arylalkyl(thio)carboxamides
    Patent number: 5721276
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which A, B, X and R.sub.1 are as defined in the description, and medicinal product containing the same useful for treating a disorder of the melatoninergic system.
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: February 24, 1998
    Assignee: Adir et Compagnie
    Inventors: Isabelle Lesieur, Patrick Depreux, Veronique Leclerc, Philippe Delagrange, Pierre Renard, Beatrice Guardiola Lemaitre
  • Tricyclic amides
    Patent number: 5712312
    Abstract: The invention relates to a compound selected from these of formula (I): ##STR1## in which R.sub.7, R.sub.8, Y, n and A are as defined in the description, and medicinal product containing the same useful for treating a disorder of the melatoninergic system.
    Type: Grant
    Filed: April 12, 1996
    Date of Patent: January 27, 1998
    Assignee: Adir et Compagnie
    Inventors: Michel Langlois, Monique Mathe-Allainmat, Philippe Delagrange, Pierre Renard, Beatrice Guardiola
  • Method of treating disorders of the melatoninergic system and a certain benzofuran containing compound
    Patent number: 5703121
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description,and Medicinal product containing the same useful for treating a disorder of the melatoninergic system.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: December 30, 1997
    Assignee: Adir Et Compagnie
    Inventors: Daniel Lesieur, Eric Fourmaintraux, Patrick Depreux, Philippe Delagrange, Pierre Renard, Beatrice Guardiola-Lemaitre
  • Alkylated (hetero) cyclic compounds
    Patent number: 5693665
    Abstract: The invention relates to a compounds selected from these of formula (I): ##STR1## in which: R.sub.1, R.sub.2, R.sub.3 and A are as defined in the description, and a medicinal product containing the same useful for treating a melatoninergic disorder.
    Type: Grant
    Filed: January 10, 1996
    Date of Patent: December 2, 1997
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Eric Fourmaintraux, Patrick Depreux, Philippe Delagrange, Pierre Renard, Beatrice Guardiola-Lemaitre
  • 5-(arloxymethyl)oxazolines
    Patent number: 5686477
    Abstract: The invention relates to compounds of formula (I): ##STR1## wherein: R.sub.1 and R.sub.2 are selected, each independently of the other, from hydrogen and an alkyl radical,A is selected from the radicals: ##STR2## wherein: R.sub.3 represents a radical selected from halogen, alkyl, alkoxy, amino, 2-acetyl, alkylamino, dialkylamino, carboxy, alkoxycarbonyl, trifluoromethyl and cyano,R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are selected, each independently of the others, from hydrogen, a halogen, an alkyl, alkoxy, amino, alkylamino, dialkylamino, carboxy, alkoxycarbonyl, cyano and a trifluoromethyl radical,R.sub.
    Type: Grant
    Filed: November 2, 1995
    Date of Patent: November 11, 1997
    Assignee: Adir et Compagnie
    Inventors: Christian Jarry, Isabelle Forfar, Jean-Jacques Bosc, Pierre Renard, Elizabeth Scalbert, Beatrice Guardiola
  • (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression
    Patent number: 5534517
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein Ar, n, B and A are as defined in the description, to their optical isomers, and to their addition salts there of with a pharmaceutically-acceptable acid or base. The compounds are useful for treating or preventing anxiety and depression.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: July 9, 1996
    Assignee: Adir Et Compagnie
    Inventors: Ousmane Diouf, Daniel Lesieur, Patrick Depreux, Beatrice Guardiola-Lemaitre, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • New aminoalkylchromones, processes for the preparation thereof
    Patent number: 5519023
    Abstract: The invention relates to compounds of the general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6 and Z are as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base and medicaments containing the same, useful in the treatment and prevention of stress, anxiety, and related ailments.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: May 21, 1996
    Assignee: Adir et Compagnie
    Inventors: Marc Payard, Genevieve Baziard-Mouysset, Gilbert De Saqui-Sannes, Beatrice Guardiola, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • 3-aminochroman compounds
    Patent number: 5510374
    Abstract: The invention relates to compounds of the formula (I): ##STR1## in which: Z represents oxygen,R.sub.1 represents alkyl,R.sub.2 represents hydrogen or alkyl,n represents 1 through 6,R.sub.3 represents unsubstituted or substituted phenylacylamino, and antidepressive and other medicinal products containing the same.
    Type: Grant
    Filed: July 18, 1994
    Date of Patent: April 23, 1996
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Beatrice Guardiola
  • Substituted piperazines for treatment of non-insulin-dependant diabetes
    Patent number: 5500426
    Abstract: A compound selected from those of formula (I): ##STR1## in which A represents ##STR2## X represents N--R.sub.4 or oxygen, and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, n and m are as defined in the description,useful in improving glucose tolerance in the treatment of non-insulin-dependent diabetes.
    Type: Grant
    Filed: April 19, 1995
    Date of Patent: March 19, 1996
    Assignee: Adir et Compagnie
    Inventors: Jean-Jacques Godfroid, Aazdine Lamouri, Estera Touboul, Xuan Wang, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola
  • Substituted piperazines for treatment of non-insulin dependent diabetes
    Patent number: 5492912
    Abstract: A compound selected from those of formula (I): ##STR1## in which A represents ##STR2## X represents N-R.sub.4 or oxygen, and R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, n and m are as defined in the description, useful in improving glucose tolerance in the treatment of non-insulin-dependent diabetes.
    Type: Grant
    Filed: July 21, 1994
    Date of Patent: February 20, 1996
    Assignee: Adir et Compagnie
    Inventors: Jean-Jacques Godfroid, Aazdine Lamouri, Estera Touboul, Xuan Wang, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola
  • Naphthylethylureas and naphthylethylthioureas
    Patent number: 5449689
    Abstract: A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are as defined in the specification, andmedicinal products containing the same which are useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: September 12, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Gerard Adam, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola-Lemaitre
  • Naphthylethylureas and naphthylethylthioureas
    Patent number: 5449690
    Abstract: A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are as defined in the specification, and medicinal products containing the same which are useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: September 12, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick DePreux, Gerard Adam, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola-Lemaitre
  • Benzoxazolinonyl substituted alkylamines
    Patent number: 5436348
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 5, 1994
    Date of Patent: July 25, 1995
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • 1-amidooctahydropyrido[2,1,-C][1,4]oxazine compounds
    Patent number: 5432173
    Abstract: The invention relates to the compounds of general formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and A are as defined in the description.their isomers, diastereoisomers, and enantiomers as well as their addition salts with a pharmaceutically acceptable inorganic or organic acid, andmedicinal products containing the same which are usable for the treatment of psycho-behavioral disorders.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: July 11, 1995
    Assignee: Adir et Compagnie
    Inventors: Henri P. Husson, Jean C. Quirion, Martine Bonin, Beatrice Guardiola, Gerard Adam, Pierre Renard