Patents by Inventor Beatrice Guardiola

Beatrice Guardiola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-aminochroman spiro compounds
    Patent number: 5420150
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, A and m are as defined in the description.Medicinal product which is useful for treating depression and anxiety.
    Type: Grant
    Filed: December 27, 1993
    Date of Patent: May 30, 1995
    Inventors: Gerald Guillaumet, Tchao Podona, Gerard Adam, Beatrice Guardiola, Pierre Renard
  • Naphthylalkylamines
    Patent number: 5420158
    Abstract: The invention relates to a compound selected from those of general formula (I): ##STR1## in which R, R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification, an optical isomer, and an addition salt thereof with a pharmaceutically-acceptable base.Medicinal product which is useful in the treatment of disorders linked to abnormal melatonin activity.
    Type: Grant
    Filed: March 23, 1993
    Date of Patent: May 30, 1995
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Daniel Lesieur, Patrick Depreux, Beatrice Guardiola-Lemaitre, Gerard Adam, Pierre Renard, Daniel H. Caignard
  • 3-aminochroman spiro compounds
    Patent number: 5397783
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, A and m are as defined in the description.Medicinal product which is useful for treating depression and anxiety.
    Type: Grant
    Filed: December 27, 1993
    Date of Patent: March 14, 1995
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Tchao Podona, Gerard Adam, Beatrice Guardiola, Pierre Renard
  • Thiochroman compounds
    Patent number: 5389668
    Abstract: The invention relates to compounds of the formula I: ##STR1## in which R.sub.1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, and medicinal products which are useful for treating Central Nervous System disorders.
    Type: Grant
    Filed: January 12, 1994
    Date of Patent: February 14, 1995
    Assignee: Adir Et Compagnie
    Inventors: Gerald Guillaumet, Gerard Coudert, Tchao Podona, Beatrice Guardiola-Lemaitre, Pierre Renard, Gerard Adam, Daniel Henri-Caignard
  • Naphthylethylureas
    Patent number: 5389683
    Abstract: A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are as defined in the specification, andmedicinal products containing the same which are in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: August 14, 1992
    Date of Patent: February 14, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Gerard Adam, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola-Lemaitre
  • (Aryl(alkyl)carbonyl)-heterocyclic compounds, compositions and use
    Patent number: 5387586
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## wherein Ar, n, B and A are as defined in the description, to their optical isomers, and to their addition salts there of with a pharmaceutically-acceptable acid or base.Medicinal product which is useful for treating pain and treating or preventing pathologies which require psychotropic agents.
    Type: Grant
    Filed: March 4, 1994
    Date of Patent: February 7, 1995
    Assignee: Adir et Compagnie
    Inventors: Ousmane Diouf, Daniel Lesieur, Patrick Depreux, Beatrice Guardiola-Lemaitre, Daniel-Henri Caignard, Pierre Renard, Gerard Adam
  • Naphthylethylureas and naphthylethylthioureas
    Patent number: 5385944
    Abstract: A compound selected from those of formula (I): ##STR1## in which the meanings of R, R.sub.1, R.sub.2 and X are defined in the specification, andmedicinal products containing the same which are useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: April 27, 1993
    Date of Patent: January 31, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Gerard Adam, Pierre Renard, Bruno Pfeiffer, Beatrice Guardiola-Lemaitre
  • Thiochroman compounds
    Patent number: 5385930
    Abstract: The invention relates to compounds of the formula I: ##STR1## in which R.sub.1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, and medicinal products which are useful for treating Central Nervous System disorders.
    Type: Grant
    Filed: January 14, 1994
    Date of Patent: January 31, 1995
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Gerard Coudert, Tchao Podona, Beatrice Guardiola-Lemaitre, Pierre Renard, Gerard Adam, Daniel Henri-Caignard
  • 2-(alkoxy benzothiazolinon-3yl) ethylamines
    Patent number: 5386034
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products. Useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: June 15, 1993
    Date of Patent: January 31, 1995
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Arylethylamine compounds
    Patent number: 5380750
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which Ar', R.sub.1 and R.sub.2 are as defined in the specification, an optical isomer,and an addition salt thereof with a pharmaceutically-acceptable acid or base.Medicinal product which is useful in treating or in preventing a disorder of the melatoninergic system.
    Type: Grant
    Filed: July 19, 1993
    Date of Patent: January 10, 1995
    Assignee: Adir et Compagnie
    Inventors: Daniel Lesieur, Said Yous, Patrick Depreux, Jean Andrieux, Gerard Adam, Daniel H. Caignard, Beatrice Guardiola
  • 3-aminochroman spiro compounds
    Patent number: 5376661
    Abstract: The invention relates to a compound selected from those of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, A and m are as defined in the description.Medicinal product which is useful for treating depression and anxiety.
    Type: Grant
    Filed: March 24, 1993
    Date of Patent: December 27, 1994
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Tchao Podona, Gerard Adam, Beatrice Guardiola, Pierre Renard
  • Thiochroman compounds
    Patent number: 5371103
    Abstract: The invention relates to compounds of the formula I: ##STR1## in which R.sub.1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, andmedicinal products which are useful for treating Central Nervous System disorders.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: December 6, 1994
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Gerard Coudert, Tchao Podona, Beatrice Guardiola-Lemaitre, Pierre Renard, Gerard Adam, Daniel Henri-Caignard
  • Alkoxy-3-[(Toluenesulfonylaminoalkyl)amino] chroman compounds
    Patent number: 5346916
    Abstract: The invention relates to compounds of the formula (I): ##STR1## in which: Z represents an oxygen atom or a sulfur atom,R.sub.1 represents a hydrogen atom or an alkyl group,R.sub.2 represents a hydrogen atom or an alkyl group,n is one to six, inclusive,R.sub.3 represents an amino group, substituted with phenylsulfonyl, andmedicinal products containing the same.
    Type: Grant
    Filed: March 16, 1993
    Date of Patent: September 13, 1994
    Assignee: Adir Et Compagnie
    Inventors: Gerald Guillaumet, Beatrice Guardiola
  • Naphthalene amides and sulphonamides, processes for their preparation and pharmaceutical compositions containing them
    Patent number: 5332759
    Abstract: The invention relates to compounds of the general formula (I): ##STR1## wherein R.sub.3 represents a group ##STR2## R.sub.1, R.sub.2, R.sub.6, R.sub.7 being as defined in the description. Medicinal product useful in treating a disorder due to vasodilatation of the vascular system.
    Type: Grant
    Filed: January 21, 1993
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Patrick Depreux, Daniel Lesieur, Habib Abdellaoui, Beatrice Guardiola, Gerard Adam, Pierre Renard, Bruno Pfeiffer
  • Thiochroman compounds
    Patent number: 5332741
    Abstract: The invention relates to compounds of the formula I: ##STR1## in which R.sub.1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, andmedicinal products which are useful for treating Central Nervous System disorders.
    Type: Grant
    Filed: May 17, 1993
    Date of Patent: July 26, 1994
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Gerard Coudert, Tchao Podona, Beatrice Guardiola-Lemaitre, Pierre Renard, Gerard Adam, Daniel Henri-Caignard
  • Benzoxazolinonyl alkylamides
    Patent number: 5326775
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: July 5, 1994
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzoxazalinonyl and benzothiazolinonyl ethyl isonicotine amides and piperidonamides
    Patent number: 5322849
    Abstract: Compounds of general formula (I): ##STR1## where R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: June 21, 1994
    Assignee: Adir Et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • Benzoxazolinonyl and benzothiazolinonyl ethyl morpholinoacetamides
    Patent number: 5322843
    Abstract: Compounds of general formula (I): ##STR1## wherein R, X, A, B and p are defined in the description. Medicinal products useful for treating sleep disorders comprising the same.
    Type: Grant
    Filed: April 28, 1993
    Date of Patent: June 21, 1994
    Assignee: Adir et Compagnie
    Inventors: Said Yous, Isabelle Lesieur, Patrick Depreux, Daniel H. Caignard, Beatrice Guardiola, Gerard Adam, Pierre Renard
  • N-[2-(7-lower-alkoxynaphth-1-yl)ethyl]benzamides
    Patent number: 5318994
    Abstract: Compounds of the formula: ##STR1## in which: A represents ##STR2## R represents linear or branched lower alkyl, R.sub.1 represents hydrogen or linear or branched lower alkyl, andR.sub.2 represents aryl or lower arylalkyl or aryl or lower arylalkyl substituted by lower alkyl, lower alkoxy, trifluoromethyl, or halogen, aryl means phenyl or naphthyl, as well as optical isomers, epimers and diastereoisomers and addition salts thereof with a pharmaceutically-acceptable acid, lower alkyl and lower alkoxy having 1 to 6 carbon atoms inclusive, andmedicaments containing the same which are useful for the treatment of disorders of the melatoninergic system.
    Type: Grant
    Filed: November 3, 1992
    Date of Patent: June 7, 1994
    Assignee: Adir et Compagnie
    Inventors: Jean Andrieux, Raymond Houssin, Said Yous, Beatrice Guardiola, Daniel Lesieur
  • 3-aminochroan compounds
    Patent number: 5314907
    Abstract: The invention relates to the derivatives of general formula (I): ##STR1## in which: Z represents an oxygen atom or a sulfur atom,R.sub.1 represents a hydrogen atom or an alkyl group,R.sub.2 represents a hydrogen atom or an alkyl group,1.ltoreq.n.ltoreq.6,R.sub.3 represents a nitrile group, an optionally substituted amino group or any one of the groups described in the description andmedicinal products containing the same.
    Type: Grant
    Filed: October 9, 1992
    Date of Patent: May 24, 1994
    Assignee: Adir et Compagnie
    Inventors: Gerald Guillaumet, Beatrice Guardiola