Abstract: Renin inhibitory peptides of the formula ##STR1## and analogs thereof inhibit renin and are useful for treating various forms of renin-associated hypertension and hyperaldosteronism.

Abstract: Peptides having the formula: ##STR1## and their use as pharmaceuticals are disclosed.

Abstract: Triazolobenzodiazepines of the formula: ##STR1## are disclosed which are antagonists of cholecystokinin (CCK).

Abstract: Renin inhibitory peptides of the formula ##STR1## and analogs thereof inhibit renin and are useful for treating various forms of renin-associated hypertension and hyperaldosteronism.

Abstract: Peptides having the formula ##STR1## and their use as pharmaceuticals are disclosed.

Abstract: A non-fermentation process for preparing a benzodiazepinedione of the formula: ##STR1## and intermediates is disclosed.

Abstract: A sampler for communicating with the interior of a vessel containing dry granular or powder materials extracts a sample of the material and conveys it to a point of collection. The sampler includes a tubular probe having an inlet opening toward an inner end and the probe is reciprocable into and out of the vessel for a flow of material into the inlet and through the probe to an outlet from the probe. To assist the material flow a jet of fluid is introduced into the inner end of the probe to aspirate material into the inlet opening and convey it through the probe, and when the probe is retracted from the vessel the jet purges the same of residual material. One or more valves are provided to control the jet of fluid and enable a momentary flow of fluid outwardly of the inlet opening when the probe is retracted to clear the opening of any material lodged therein.

Abstract: Novel quinazolino-1,4-benzodiazepin-5,13-diones, which have been found to be antagonists of the function of cholecystokinins (CCK), to the preparation of these compounds from compounds prepared by aerobic fermentation of certain Aspergillus alliaceus strains, and to the use of these compounds to antagonize the function of CCK, which antagonism is useful, e.g., for the treatment and prevention of disorders of the gastrointestinal, central nervous and appetite-regulatory systems of mammals, especially of humans.

Abstract: Novel quinazolino-1,4-benzodiazepin-5,13-dione derivatives, which are soluble in aqueous media and which have been found to be antagonists of the function of cholecystokinins (CCK), to the preparation of these compounds from compounds prepared by aerobic fermentation of certain Aspergillus alliaceus strains, and to the use of these compounds to antagonize the function of CCK, which antagonism is useful, e.g., for the treatment and prevention of disorders of the gastrointestinal, central nervous and appetite-regulatory systems of mammals, especially of humans.

Abstract: Novel indol-3-yl-quinazolino-1,4-benzodiazepin-5,13-diones, which are antagonists of the function of cholecystokinins (CCK), to the preparation of these compounds from compounds prepared by aerobic fermentation of certain Aspergillus alliaceus strains, and to the use of these compounds to antagonize the function of CCK, which antagonism is useful, e.g., for the treatment and prevention of disorders of the gastrointestinal, central nervous and appetite-regulatory systems of mammals, especially of humans.

Abstract: A device for measuring forces exerted by the jaws of a chuck under both static and dynamic rotary conditions is characterized by an elongate housing and a piston in a cylinder bore in the housing and extending generally perpendicular thereto. The piston and housing are adapted to be gripped between the jaws of the chuck to pressurize a fluid in the cylinder, and the pressure of the fluid is coupled with a gauge which is moved out of an end of the housing by an amount in accordance with the pressure, and therefore in accordance with the force exerted by the jaws, and a graduated scale on the gauge provides a visual indication of the force.

Abstract: Apparatus for spinning viscose rayon comprising an acid bath having an enclosure arranged for substantially completely trapping and collecting any gases emanating from said bath, a plurality of fiber-forming jets disposed substantially along beneath the surface of said acid bath, means for forcing aqueous xanthated alkali cellulose in liquid form into said jets and through said jets upwardly into said bath, and take-up means located within said enclosure above said bath for taking up the resulting fibers in an upward direction within said enclosure, and thence through an enclosed secondary hot bath for the purpose of stretching the cellulose-xanthate, regenerating it to cellulose, and for trapping and collecting gases and other chemicals.

Abstract: A sampler for communicating with the interior of a vessel containing a relatively viscous liquid under pressure extracts a liquid sample of predetermined volumetric displacement from the vessel and conveys the same to a point of collection. The sampler includes a body having a bore in communication with the interior of the vessel, a plunger reciprocable within the bore and a slider reciprocable within the bore rearwardly of the plunger. To obtain a liquid sample, the plunger is moved at least partially into the vessel to establish a sample chamber between the slider and plunger into which liquid flows. The plunger is then moved back into the bore with the sample captured between the plunger and slider until the sample is exposed to a discharge port in the bore, at which point further rearward movement of the sleeve is inhibited, so that continued rearward movement of the plunger forces the liquid out of the sample chamber and through the port.

Abstract: A cylinder is provided with a piston therein having a piston rod screw threadably engaging through one end cap so that rotation of the rod moves the piston along the cylinder. A filler is situated in the other end cap thus allowing the cylinder to be filled with refrigerant oil. An injection assembly is connected to the other end cap and includes a valve, a tube and a connector which may be connected to the high or low side of the refrigerant circuit of a refrigeration assembly such as an air conditioner. Once connected to the refrigerant circuit, a loosening of one union allows the refrigerant within the circuit to purge the line whereupon the union is tightened. The piston rod is marked with indicia along the length thereof so that rotation of the rod a predetermined distance indicates to the operator that a given amount of oil has been ejected from the cylinder and into the refrigerant system.

Abstract: An improved milking parlor construction comprising the combination of a modular unit which comprises a module which may be utilized in fabricating milking parlors of the type wherein a central milking pit area has juxtapositioned on either side a cattle stand wherein each of the modules is composed of a vertical upright member that may be supported in concrete or the like and from which a feed bowl and shroud and individual cattle feeding station gate may be hung. Superpositioned over the vertical upright, which is of hollow construction, is a feed conveyor having communication to the vertical upright member which has a feed chute terminating in the feed bowl by which feed may be fed to the feed bowl of each of the cattle stations. Means are utilized whereby one or plurality of the gates defining a captive station at which the cattle are milked and, incidentally fed, provides easy egress for the cattle to the exit corridor to leave the milking parlor structure.

Abstract: Dibenzo[a,d]cycloocten-5,12-(and 6,12)-imines, derivatives and pharmaceutically acceptable salts thereof are useful as anxiolytics, antidepressants, anticonvulsants, muscle relaxants and in the treatment of mixed anxiety-depression, minimal brain dysfunction and extrapyramidal disorders such as Parkinson's disease.

Abstract: 5-Substituted-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines, derivatives and pharmaceutically acceptable salts thereof are useful as anticonvulsants.

Abstract: Statine (Sta), a naturally-occurring amino acid and closely related derivatives, are prepared by a novel method involving an oxidative route to the requisite chiral .alpha.-aminoaldehyde intermediate, L-leucinal; the novel method may be illustrated by the following reaction scheme: ##STR1## .

Abstract: In stanchion constructions of the type used in feeding lots and/or milking parlors, it is desirable to be able to control the cattle stations as by locking the cattle in captive positions or, alternatively, having the cattle stations remain open to permit free feeding and the like.The herein disclosed invention employs simple mechanical expedients, not requiring expensive forming techniques and having simple structure such as an elongate bar or rod with simple abutments formed, if desired, by through bolts and nuts to cooperate with a simple latching member to provide the captive position at the cattle stations.The elongate member is supported for linear and radial or rotational movement, so as to permit selective positioning of the pivotal members making up the cattle receiving stations in a simple, expedient manner, requiring little, if any, maintenance and construction sophistication.