Patents by Inventor Benjamin Matthews

Benjamin Matthews has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250134949
    Abstract: Described herein are compositions and methods for treating a lung disorder associated with dysregulated VEGF signaling. The PR1P peptide (DRVQRQTTTVVA, SEQ ID NO: 1) and variants thereof are able to enhance VEGF signaling in the lungs and reduce lung cell apoptosis (e.g., induced by toxicity or injury), thus treating the disorder.
    Type: Application
    Filed: June 12, 2024
    Publication date: May 1, 2025
    Applicant: Children's Medical Center Corporation
    Inventors: Avner Adini, Benjamin Matthews
  • Publication number: 20240099592
    Abstract: A system includes a sensor configured to generate thoracic impedance data associated with a patient for a period of time, a memory storing machine-readable instructions, and a control system communicatively coupled to the sensor. The control system is arranged to provide control signals to one or more electronic devices and including one or more processors configured to execute the machine-readable instructions to analyze the generated thoracic impedance data associated with the patient; determine, based at least in part on the analysis, respiratory function signals and cardiac function signals, and whether the respiratory function signals and cardiac function signals satisfies a predetermined threshold, and cause an operation of the one or more electronic devices to be modified in response to determining the respiratory function signals and cardiac function signals satisfies the predetermined threshold.
    Type: Application
    Filed: October 8, 2020
    Publication date: March 28, 2024
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Benjamin MATTHEWS, Christopher NORVE
  • Publication number: 20200230199
    Abstract: Described herein are compositions and methods for treating a lung disorder associated with dysregulated VEGF signaling. The PR1P peptide (DRVQRQTTTVVA, SEQ ID NO: 1) and variants thereof are able to enhance VEGF signaling in the lungs and reduce lung cell apoptosis (e.g., induced by toxicity or injury), thus treating the disorder.
    Type: Application
    Filed: June 1, 2018
    Publication date: July 23, 2020
    Applicant: Children's Medical Center Corporation
    Inventors: Avner Adini, Benjamin Matthews
  • Publication number: 20180361062
    Abstract: A physiologic sensor module includes at least one wearable sensor that is configured for wearing on a human body part and for measuring at least one biological signal. The module further includes at least one controller communicatively coupled to the wearable sensor and configured to receive the biological signal from the wearable sensor. The controller is further configured to process the biological signal in real-time, extract one or more clinical features from the biological signal, and based on the clinical features, determine detection of anaphylaxis.
    Type: Application
    Filed: August 22, 2018
    Publication date: December 20, 2018
    Inventors: Andy H. Levine, Christoph Matthias Kanzler, Aymeric Guy, Daniel Leo Miranda, Joseph Mooney, Adam Zapotok, Samuel Berry, Huy Lam, Jonathan Sabaté del Río, John Osborne, Mustafa Karabas, Alan Dunne, James Niemi, Benjamin Matthews, Donald E. Ingber, Olivier Henry, Premananda Pai Indic
  • Publication number: 20180333533
    Abstract: An injector module includes a housing, a reservoir, a superelastic needle, and an actuator. The reservoir is positioned in the housing and stores epinephrine therein. The superelastic needle is positioned within the housing in a retracted position and is fluidly coupled with the reservoir. The superelastic needle has a gauge between eighteen and twenty-five. The actuator is configured to apply an actuator force on the superelastic needle such that the superelastic needle is moved from the retracted position to an injecting position where a tip of the superelastic needle protrudes from the housing between about fifteen millimeters and about thirty-five millimeters.
    Type: Application
    Filed: May 4, 2018
    Publication date: November 22, 2018
    Inventors: Andy H. Levine, Cristoph Matthias Kanzler, Aymeric Guy, Daniel Leo Miranda, Joseph Mooney, Adam Zapotok, Samuel Berry, Huy Lam, Jonathan Sabaté del Río, John Osborne, Mustafa Karabas, Alan Dunne, James Niemi, Benjamin Matthews, Donald E. Ingber, Olivier Henry, Premananda Pai Indic
  • Patent number: 10080841
    Abstract: A physiologic sensor module includes at least one wearable sensor that is configured for wearing on a human body part and for measuring at least one biological signal. The module further includes at least one controller communicatively coupled to the wearable sensor and configured to receive the biological signal from the wearable sensor. The controller is further configured to process the biological signal in real-time, extract one or more clinical features from the biological signal, and based on the clinical features, determine detection of anaphylaxis.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: September 25, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Andy H. Levine, Christoph Matthias Kanzler, Daniel Leo Miranda, Joseph Mooney, Huy Lam, John Osborne, Mustafa Karabas, Alan Dunne, James Niemi, Benjamin Matthews, Donald E. Ingber, Olivier Henry, Premananda Pai Indic
  • Publication number: 20170239418
    Abstract: A physiologic sensor module includes at least one wearable sensor that is configured for wearing on a human body part and for measuring at least one biological signal. The module further includes at least one controller communicatively coupled to the wearable sensor and configured to receive the biological signal from the wearable sensor. The controller is further configured to process the biological signal in real-time, extract one or more clinical features from the biological signal, and based on the clinical features, determine detection of anaphylaxis.
    Type: Application
    Filed: May 10, 2017
    Publication date: August 24, 2017
    Inventors: Andy H. Levine, Christoph Matthias Kanzler, Aymeric Guy, Daniel Leo Miranda, Joseph Mooney, Adam Zapotok, Samuel Berry, Huy Lam, Jonathan Sabaté del Río, John Osborne, Mustafa Karabas, Alan Dunne, James Niemi, Benjamin Matthews, Donald E. Ingber, Olivier Henry, Premananda Pai Indic
  • Publication number: 20160319301
    Abstract: The invention relates to methods and compositions for increasing resistance to infection by soybean cyst nematode on a soybean plant, plant part or plant cell. Nucleotide sequences that confer resistance to soybean cyst nematode when expressed in soybean are provided.
    Type: Application
    Filed: July 14, 2016
    Publication date: November 3, 2016
    Inventors: Xiang Huang, Benjamin Matthews
  • Publication number: 20140090105
    Abstract: The invention relates to methods and compositions for increasing resistance to infection by soybean cyst nematode on a soybean plant, plant part or plant cell. Nucleotide sequences that confer resistance to soybean cyst nematode when expressed in soybean are provided.
    Type: Application
    Filed: September 26, 2013
    Publication date: March 27, 2014
    Applicants: The United States of America, as Represented by the Secretary of Agriculture, Syngenta Participations AG
    Inventors: Xiang Huang, Benjamin Matthews