Abstract: Described herein are compositions and methods for treating a lung disorder associated with dysregulated VEGF signaling. The PR1P peptide (DRVQRQTTTVVA, SEQ ID NO: 1) and variants thereof are able to enhance VEGF signaling in the lungs and reduce lung cell apoptosis (e.g., induced by toxicity or injury), thus treating the disorder.

Abstract: Techniques and systems to reduce deflection of a riser extending from an offshore vessel. A device may include a fairing assembly having a body segment configured to at least partially circumferentially surround a main tube of a riser joint of the riser, and a tail segment. The tail segment is configured to retract into a collapsed position and extend into an expanded position along an expansion direction. An expanded width of the fairing assembly in the expanded position is between 20 to 200 percent greater than a collapsed width of the fairing assembly. In some embodiments, the collapsed width of the fairing assembly is less than 1.5 times a length across the main tube, and an expanded width of the fairing assembly is greater than 1.5 times the length of the main tube.

Abstract: Techniques and systems to reduce deflection of a riser extending from an offshore vessel. A device may include a fairing assembly having a body segment configured to at least partially circumferentially surround a main tube of a riser joint of the riser, and a tail segment. The tail segment is configured to retract into a collapsed position and extend into an expanded position along an expansion direction. An expanded width of the fairing assembly in the expanded position is between 20 to 200 percent greater than a collapsed width of the fairing assembly. In some embodiments, the collapsed width of the fairing assembly is less than 1.5 times a length across the main tube, and an expanded width of the fairing assembly is greater than 1.5 times the length of the main tube.

Abstract: Aspects of the disclosure provide for a circuit. In some examples, the circuit includes an amplifier having a first input configured to receive a signal representative of a condition related to a power converter, a second input configured to receive a reference signal, and an output, a PWM regulation circuit having an input coupled to the output of the amplifier, a first output configured to provide a first control signal for a high-side transistor of the power converter, and a second output configured to output a first control signal for a low-side transistor of the power converter, and a PFM regulation circuit having an input coupled to the output of the first amplifier, a first output configured to output a second control signal for the high-side transistor of the power converter, and a second output configured to output a second control signal for the low-side transistor of the power converter.

Abstract: An aerial rope tramway or slope hoist system suitable for use in an open pit mine or similar application. According to an embodiment, the aerial slope hoist system comprises an upper station and a lower station. The upper station is configured in proximity to a surface section of the open pit and the lower station is configured at a lower section of the open pit mine. According to an embodiment, the upper station comprises first and second towers and the lower station comprises first and second towers. The towers are configured to support respective ends of first and second suspension cable assemblies. Each of the suspension cable assemblies is configured to support and carry a trolley or skip. The system comprises a hoist configured to move the respective trolleys in opposite directions. The towers for the lower station are configured to be moveable and provide the capability to break down the system and/or lengthen or reduce the span of the system.

Abstract: Techniques and systems to provide pressure reduction of a fluid, for example, from a well. A device includes an input configured to be fluidly coupled to a well control device. The device also includes an output configured to be to be fluidly coupled to the well control device. The device further includes at least one valve configured to alter a pressure of a fluid received at the input and transmitted from the output.

Abstract: A physiologic sensor module includes at least one wearable sensor that is configured for wearing on a human body part and for measuring at least one biological signal. The module further includes at least one controller communicatively coupled to the wearable sensor and configured to receive the biological signal from the wearable sensor. The controller is further configured to process the biological signal in real-time, extract one or more clinical features from the biological signal, and based on the clinical features, determine detection of anaphylaxis.

Abstract: An injector module includes a housing, a reservoir, a superelastic needle, and an actuator. The reservoir is positioned in the housing and stores epinephrine therein. The superelastic needle is positioned within the housing in a retracted position and is fluidly coupled with the reservoir. The superelastic needle has a gauge between eighteen and twenty-five. The actuator is configured to apply an actuator force on the superelastic needle such that the superelastic needle is moved from the retracted position to an injecting position where a tip of the superelastic needle protrudes from the housing between about fifteen millimeters and about thirty-five millimeters.

Abstract: A physiologic sensor module includes at least one wearable sensor that is configured for wearing on a human body part and for measuring at least one biological signal. The module further includes at least one controller communicatively coupled to the wearable sensor and configured to receive the biological signal from the wearable sensor. The controller is further configured to process the biological signal in real-time, extract one or more clinical features from the biological signal, and based on the clinical features, determine detection of anaphylaxis.

Abstract: An aerial rope tramway or slope hoist system suitable for use in an open pit mine or similar application. According to an embodiment, the aerial slope hoist system comprises an upper station and a lower station. The upper station is configured in proximity to a surface section of the open pit and the lower station is configured at a lower section of the open pit mine. According to an embodiment, the upper station comprises first and second towers and the lower station comprises first and second towers. The towers are configured to support respective ends of first and second suspension cable assemblies. Each of the suspension cable assemblies is configured to support and carry a trolley or skip. The system comprises a hoist configured to move the respective trolleys in opposite directions. The towers for the lower station are configured to be moveable and provide the capability to break down the system and/or lengthen or reduce the span of the system.

Abstract: Yeast cells are genetically modified to disrupt a native metabolic pathway from dihydroxyacetone to glycerol. In certain aspects, the yeast cell is of the genera Kluyveromyces, Candida or Issatchenkia. In other aspects, the yeast cell is capable of producing at least one organic acid, such as lactate. The yeast cells produce significantly less glycerol than the wild-type strains, and usually produce greater yields of desired fermentation products. Yeast cells of the invention often grow well when cultivated, despite their curtailed glycerol production.

Abstract: Techniques and systems to provide pressure reduction of a fluid, for example, from a well. A device includes an input configured to be fluidly coupled to a well control device. The device also includes an output configured to be to be fluidly coupled to the well control device. The device further includes at least one valve configured to alter a pressure of a fluid received at the input and transmitted from the output.

Abstract: A physiologic sensor module includes at least one wearable sensor that is configured for wearing on a human body part and for measuring at least one biological signal. The module further includes at least one controller communicatively coupled to the wearable sensor and configured to receive the biological signal from the wearable sensor. The controller is further configured to process the biological signal in real-time, extract one or more clinical features from the biological signal, and based on the clinical features, determine detection of anaphylaxis.

Abstract: The invention relates to methods and compositions for increasing resistance to infection by soybean cyst nematode on a soybean plant, plant part or plant cell. Nucleotide sequences that confer resistance to soybean cyst nematode when expressed in soybean are provided.

Abstract: The present invention provides Rotavirus antigenic polypeptides or antigens that elicit an immune response in animal or human against rotavirus, compositions comprising said rotavirus polypeptides, methods of vaccination against rotavirus, and kits for use with such methods and compositions. The invention further provide novel expression vectors for producing the vaccine antigenic polypeptides.

Abstract: Ultrasound thin film tags are disclosed. The tags include a pattern of regions, wherein the pattern is configured to create thin film interference when scanned with ultrasound energy. The tags can be placed in various locations within the article including interior surfaces and they can be used to encode a variety of information about the article. Devices and methods for scanning and decoding the tags are also disclosed.

Abstract: A method of an apparatus control pressure in the patient interface. A vent valve may be used with a respiratory device, where the vent valve may selectively block fluid communication between components, such as the flow generator, the patient interface, and/or the vent. An expiratory flow model may be used to determine an expiratory characteristic such as an expiratory flow rate or pressure in the patient interface where an indicative measure may not be available. The expiratory flow model may receive inputs based on a measure of the patient's respiration, such as the tidal volume, peak inspiratory flow rate or length of inspiration. The expiratory characteristic may be used by a controller to control a pressure in the patient interface to provide respiratory therapy to a patient at or close to a target pressure.

Abstract: Disclosed herein are compositions and methods for treating or preventing the build-up or entrapment of fecal matter in the colon. The compositions and methods disclose a delayed release laxative that provides for the release of the laxative if colon-specific conditions are achieved, otherwise the laxative passes out of the body. The condition specific release of laxatives prevents harmful side effects from excessive use of non-delayed release laxatives.

Abstract: The present invention encompasses porcine epidemic diarrhea virus (PEDV) vaccines or compositions. The vaccine or composition may be a vaccine or composition containing inactivated PEDV. The invention also encompasses epitopes or immunogens which can be used to protect porcine animals against PEDV.

Abstract: Technologies are disclosed for a method and a device for detecting device colonization. Disclosed herein is an indwelling medical device configured to detect a biofilm. The device comprises a substrate configured to contact blood and a detecting material, disposed with the substrate, configured to detect the presence of a biofilm thereon. The detecting material is soluble in blood, removable by kidneys from the blood, and passable to urine by the kidneys for detection in the urine. A method for detecting the growth of a biofilm on an indwelling medical and a method for making an indwelling medical device are also disclosed herein.