Patents by Inventor Bernhard Kutscher

Bernhard Kutscher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroary1 derivatives and their use as medicaments
    Patent number: 6638935
    Abstract: The invention relates to novel pyridine derivatives of formula 1, to their preparation and to their use as medicaments, in particular for treating tumors
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: October 28, 2003
    Assignee: Zentaris AG
    Inventors: Peter Emig, Eckhard Günther, Bernhard Kutscher, Bernd Nickel, Jürgen Schmidt, Anita Storch
  • LHRH antagonists having improved solubility properties
    Patent number: 6627609
    Abstract: The invention relates to peptides which contain N-methylated amino acid units and have improved water solubility. Medicaments in which the peptides according to the invention are contained can be used for the treatment of hormone-dependent tumours and hormone-influenced non-malignant disorders.
    Type: Grant
    Filed: March 14, 2000
    Date of Patent: September 30, 2003
    Assignee: Zentaris AG
    Inventors: Michael Bernd, Bernhard Kutscher, Eckhard Günther, Peter Romeis, Thomas Reissmann, Thomas Beckers
  • Methods of modulating serine/threonine protein kinase function with azabenzimidazole-based compounds
    Publication number: 20030181480
    Abstract: The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with azabenzimidazole-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to azabenzimidazole compounds and pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: November 15, 2002
    Publication date: September 25, 2003
    Applicant: Zentaris AG
    Inventors: Gerald McMahon, Heinz Weinberger, Bernhard Kutscher, Harald App
  • Novel phospholipid derivatives
    Publication number: 20030153533
    Abstract: Novel phospholipid derivatives of the General Formula I: 1
    Type: Application
    Filed: November 8, 2002
    Publication date: August 14, 2003
    Applicant: Zentaris AG
    Inventors: Gerhard Nossner, Bernhard Kutscher, Jurgen Engel, Wolfgang Schumacher, Jurij Stekar, Peter Hilgard
  • Process for the preparation of oxazaphosphorine-2-amines
    Publication number: 20030109737
    Abstract: A process for the preparation of oxazaphosphorine-2-amines of the formula (I) described by the reaction scheme 1
    Type: Application
    Filed: January 8, 2003
    Publication date: June 12, 2003
    Inventors: Ulf Niemeyer, Harald Niegel, Bernhard Kutscher, Ion Neda
  • Modifications of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene, and processes for their preparation
    Patent number: 6538151
    Abstract: The invention relates to novel modifications of the compound 2-amino-4-(4-fluorobenzylamino)-1-ethoxy-carbonylaminobenzene of the processes for their preparation and their use in pharmaceutical compositions.
    Type: Grant
    Filed: October 29, 1998
    Date of Patent: March 25, 2003
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Peter Meisel, Karl-Friedrich Landgraf, Jürgen Schäfer, Wilfried Thiel, Matthias Rischer, Alfred Olbrich, Bernhard Kutscher
  • Methods of using therapeutic phospholipid derivatives
    Patent number: 6479472
    Abstract: A method of treating protozoal and fungal diseases is described, in which an effective amount of a compound of formula I is administered to a host having a protozoal or fungal disease.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: November 12, 2002
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Gerhard Nössner, Bernhard Kutscher, Jürgen Engel, Wolfgang Schumacher, Jurij Stekar, Peter Hilgard
  • N-substituted indole-3glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action
    Publication number: 20020161025
    Abstract: The invention relates to novel N-substituted indole-3-glyoxylamides, to processes for their preparation and to their pharmaceutical use. The compounds have antiasthmatic, antiallergic and immunosuppressant/immunomodulating actions.
    Type: Application
    Filed: January 30, 2002
    Publication date: October 31, 2002
    Inventors: Guillaume Lebaut, Cecilia Menciu, Bernhard Kutscher, Peter Emig, Stefan Szelenyi, Kay Brune
  • Novel heteroary1 derivatives and their use as medicaments
    Publication number: 20020111354
    Abstract: The invention relates to novel pyridine derivatives of formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Application
    Filed: July 20, 2001
    Publication date: August 15, 2002
    Inventors: Peter Emig, Eckhard Gnther, Bernhard Kutscher, Bernd Nickel, J?uuml;rgen Schmidt, Anita Storch
  • Novel heteroaryl derivatives and their use as medicaments
    Publication number: 20020103214
    Abstract: The invention relates to novel quinoline derivatives of the formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Application
    Filed: July 20, 2001
    Publication date: August 1, 2002
    Inventors: Peter Emig, Eckhard Gnther, J?uuml;rgen Schmidt, Bernd Nickel, Bernhard Kutscher
  • N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action
    Patent number: 6344467
    Abstract: The invention relates to novel N-substituted indole-3-glyoxylamides, to processes for their preparation and to their pharmaceutical use. The compounds have antiasthmatic, antiallergic and immunosuppressant/immunomodulating actions.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: February 5, 2002
    Assignee: ASTA Medica AG
    Inventors: Guillaume Lebaut, Cécilia Menciu, Bernhard Kutscher, Peter Emig, Stefan Szelenyi, Kay Brune
  • Process for the preparation of oxazaphosphorine-2-amines
    Publication number: 20010047103
    Abstract: A process for the preparation of oxazaphosphorine-2-amines of the formula (I) described by the reaction scheme 1
    Type: Application
    Filed: December 7, 2000
    Publication date: November 29, 2001
    Applicant: Asta Medica Aktiengesellschaft
    Inventors: Ulf Niemeyer, Harald Niegel, Bernhard Kutscher, Ion Neda
  • Methods of modulating serine/threonine protein kinase function with quinazoline-based compounds
    Publication number: 20010014679
    Abstract: The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with quinazoline-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to quinazoline compounds and pharmaceutical compositions comprising these compounds.
    Type: Application
    Filed: January 26, 2001
    Publication date: August 16, 2001
    Inventors: Peng C. Tang, Gerald McMahon, Heinz Weinberger, Bernhard Kutscher, Harald App
  • Specific immunophilin ligands as antiasthmatics and immunosuppressants
    Patent number: 6258815
    Abstract: The novel specific immunophilin ligands of the general formula I have an antiasthmatic and immunosuppressive action and are suitable for the preparation of drugs.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: July 10, 2001
    Assignee: ASTA Medica Aktiengesellschaft
    Inventors: Dietmar Reichert, Bernhard Kutscher, Holger Bang, Kay Brune, Gerhard Quinkert, Hans-Günter Schaible
  • Methods of modulating serine/thereonine protein kinase function with quinazoline-based compounds
    Patent number: 6204267
    Abstract: The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with quinazoline-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to quinazoline compounds and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: May 1, 1998
    Date of Patent: March 20, 2001
    Assignee: Sugen, Inc.
    Inventors: Peng C. Tang, Gerald McMahon, Heinz Weinberger, Bernhard Kutscher, Harald App
  • Methods of modulating serine/threonine protein kinase function with 5-azaquinoxaline-based compounds
    Patent number: 6180631
    Abstract: The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with 5-azaquinoxaline-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to 5-azaquinoxaline compounds and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: October 5, 1998
    Date of Patent: January 30, 2001
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Gerald McMahon, Heinz Weinberger, Bernhard Kutscher, Harald App
  • Phospholipid derivatives
    Patent number: 6172050
    Abstract: Phospholipid derivatives of Formula X: wherein A is the ring system in which R is a linear or branched alkyl radical having 10 to 24 carbon atoms which may contain one or more double or triple bonds; R1 and R2 are independently hydrogen or linear alkyl radicals having 1 to 3 carbon atoms; y is 0, 1, 2 or 3; m and n are independently 0 or in an integer, with the proviso that m+n is between 2 and 8; or A is a tropanio or quinuclidinio ring system, which is linked via a carbon-carbon bond and is optionally substituted by one or more methyl groups; processes for the preparation of the derivatives, and methods for treating tumors therewith.
    Type: Grant
    Filed: August 4, 1997
    Date of Patent: January 9, 2001
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Gerhard Nössner, Bernhard Kutscher, J{umlaut over (u)}rgen Engel, Wolfgang Schumacher, Jurij Stekar, Peter Hilgard
  • Methods of modulating serine/threonine protein kinase function with azabenzimidazole-based compounds
    Patent number: 6093728
    Abstract: The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with azabenzimidazole-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In addition, the invention describes methods of preventing and treating serine/threonine protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to azabenzimidazole compounds and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: July 25, 2000
    Assignee: Asta Medica Aktiengesellschaft
    Inventors: Gerald McMahon, Heinz Weinberger, Bernhard Kutscher, Harald App
  • N-substituted indole-3 glyoxylamides having anti-asthmatic antiallergic and immunosuppressant/immuno-modulating action
    Patent number: 6008231
    Abstract: The invention relates to novel N-substituted indole-3-glyoxylamides, to processes for their preparation and to their pharmaceutical use. The compounds have antiasthmatic, antiallergic and immuno-suppressant/immunomodulating actions.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: December 28, 1999
    Assignee: ASTA Medica Aktiengesellschgt
    Inventors: Guillaume Lebaut, Cecilia Menciu, Bernhard Kutscher, Peter Emig, Stefan Szelenyi, Kay Brune
  • Nova- and decapeptides in the preparation of a drug for the treatment of aids
    Patent number: 5985834
    Abstract: Described are LHRH-antagonistic and bombesin-antagonistic nona- and decapeptides suitable for use in the preparation of a drug for the treatment of AIDS and ARC as well as for use in the preparation of an immunostimulation drug.
    Type: Grant
    Filed: December 18, 1995
    Date of Patent: November 16, 1999
    Assignee: ASTA Medica AG
    Inventors: Jurgen Engel, Bernhard Kutscher, Michael Bernd, Ulf Niemeyer