Abstract: A random data generation circuit includes: a first shift register and a second shift register. The first shift register includes n output ends Q1 to Qn, the second shift register includes n output ends Qn+1 to Q2n, and each of the output ends outputs 1-bit data in a clock cycle of a clock signal; and a parallel-to-serial circuit, coupled to the output ends Q1 to Q2n and configured to convert parallel data output from Q1 to Q2n in a clock cycle into serial data for output. An initial value of the first shift register is different from an initial value of the second shift register. Data may be generated in parallel by using two shift registers, and the parallel data generated by the two shift registers is converted into serial data by using the parallel-to-serial circuit to be output.

Abstract: Consistent with the present disclosure, a method and related system for secure autonomic optical transport networks are disclosed. The method includes steps for adding a network element in an optical network. The method includes an initial step of verifying, with a new network element, a first identifier certificate from a proxy network element. In a further step, a second identifier certificate from the new network element is verified with the proxy element. A registrar is used for verifying the second identifier certificate from the proxy network element and sending domain specific parameters to the proxy network element for forwarding to the new network element Next, a local certificate is generated on the new network element. The local certificate is derived from a secure module and sent to the proxy network element for forwarding to the registrar. Further, the new network element in the autonomic domain is enrolled, with the registrar.

Abstract: A data processing method and system for a distributed database, and a device and a storage medium. The method comprises: sorting transactions in a transQueue by using a global timestamp TSO, creating a local transaction list by means of an XA Event and a waitTrans in the transQueue, and generating first-level sorting queues according to the local transaction list (102); for the first-level sorting queue of each DN, performing multi-path merging and sorting, so as to generate a global sorting queue (104); and for the global sorting queue, merging local transactions that have the same global timestamp TSO, and generating a global binary log Binlog (106). Therefore, the global orderliness and integrity of transactions during the process of processing and replicating data in a distributed database are ensured.

Abstract: Embodiments of the present application provide a data processing method, a distributed database system, an electronic device and a computer storage medium, wherein a data processing method is applied to a shard node of a distributed database system. The method comprises: receiving a physical DDL instruction converted from a logic DDL instruction for change of data in the distributed database system; executing the physical DDL instruction and generating a shard node mode snapshot for the shard node after the physical DDL instruction has been successfully executed; and if it is determined that the shard node mode snapshot is inconsistent with a global logic mode snapshot of the distributed database system, adjusting log data of the shard node aggregated into a global log to be consistent with the global logic mode snapshot.

Abstract: This application relates to the artificial intelligence field, and in particular, to an item recommendation method and apparatus, and a storage medium. The method includes: obtaining historical interaction data of a target object, where the historical interaction data indicates a historical interaction event between the target object and at least one item; obtaining a pre-trained target recommendation model, where the target recommendation model includes a graph neural network model with one convolutional layer, and the convolutional layer indicates an association relationship between a sample object and a sample item; and invoking, based on the historical interaction data, the target recommendation model to output a target item corresponding to the target object. In the embodiments of this application, a framework structure of the target recommendation model is simplified, so that model operation time is greatly reduced.

Abstract: A unified platform including an exosome-based method has been developed that uses only immunogenic epitopes for nanovaccine production. By eliminating these nonessential sequences from the full-length antigen, this new type of nanovaccine is safer as compared to those of existing vaccines. In addition, careful selection of targeting epitopes and incorporation of multiple epitope repeats into nanovaccine will make it more potent and precise than the traditional vaccines.

Abstract: Disclosed are an oxa-azasipro derivative, a preparation method therefor and a pharmaceutical use thereof. In particular, disclosed are an oxa-azasipro derivative as represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, and the use thereof as a therapeutic agent, especially the use thereof as a PI3K? inhibitor and the use thereof in the preparation of a drug for treating diseases or conditions improved by means of inhibiting PI3K?.

Abstract: Provided are a flexible insulated air duct and a modular flexible insulated air-duct system; the flexible insulated air duct includes an air-duct main body (1); the air-duct main body (1) includes an inner air-duct layer (5) and a heat-insulating layer (4) integrally formed on the inner air-duct layer (5); the inner air-duct layer (5) is arranged inside the heat-insulating layer (4), and the heat-insulating layer (4) is a rubber/plastic material. The modular flexible insulated air-duct system made by assembling a main air duct (7), a branched air duct (8), and a connecting air duct (9) may be rapidly connected on-site using a zip fastener to form an air-duct system having any configuration.

Abstract: Aerosol formulations of granisetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative nausea and vomiting (PONV) using the inhalation formulations.

Abstract: Aerosol formulations of ondansetron useful for pulmonary delivery are provided. The formulations are useful in the reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative nausea and vomiting (PONY) using the inhalation formulations.

Abstract: The present invention discloses a multilayer composite rubber-plastic foam insulation material and a preparation method thereof. The composite rubber-plastic foam insulation material includes a two-layer structure; the two-layer structure includes an insulation layer and a first functional layer; the insulation layer and the first functional layer are both made of a rubber-plastic foam material; the first functional layer and the insulation layer are integrally molded by blending extrusion and vulcanization foaming, and the first functional layer and the insulation layer form an integral structure. The multilayer composite rubber-plastic foam insulation material provided by the present invention adopts a vulcanization foaming integral molding process, and not only ensures the thermal insulation property of the insulation layer, but also gives the functional layer corresponding functions by selecting different functional polymers, thereby satisfying a variety of personalized needs in engineering applications.

Abstract: The present disclosure provides for palonosetron formulations, such as aerosol formulations of palonosetron for pulmonary delivery. Also provided are uses of the formulation, such as reduction, elimination or prevention of nausea and vomiting associated with chemotherapy, radiation therapy, or surgery. Also provided are novel methods to treat chemotherapy-induced nausea and vomiting (CINV), radiation-induced nausea and vomiting (RINV), and post-operative nausea and vomiting (PONV) using the inhalation formulations.

Abstract: Provided are a flexible insulated air duct and a modular flexible insulated air-duct system; the flexible insulated air duct includes an air-duct main body (1); the air-duct main body (1) includes an inner air-duct layer (5) and a heat-insulating layer (4) integrally formed on the inner air-duct layer (5); the inner air-duct layer (5) is arranged inside the heat-insulating layer (4l), and the heat-insulating layer (4) is a rubber/plastic material. The modular flexible insulated air-duct system made by assembling a main air duct (7), a branched air duct (8), and a connecting air duct (9) may be rapidly connected on-site using a zip fastener to form an air-duct system having any configuration.

Abstract: A heteroaryl[4,3-c]pyrimidin-5-amine derivative, a preparation method therefor, and medical uses thereof are provided. Specifically, a heteroaryl[4,3-c]pyrimidin-5-amine derivative of formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, and uses thereof as therapeutic agents are provided. In particular, the provided compounds can be used as A2a receptor antagonists and for treatment of conditions or symptoms that are ameliorated by inhibiting the A2a receptor. The various substituent groups in the formula (I) have the meanings as described in the specification.

Abstract: Provided are a flexible insulated air duct and a modular flexible insulated air-duct system; the flexible insulated air duct includes an air-duct main body (1); the air-duct main body (1) includes an inner air-duct layer (5) and a heat-insulating layer (4) integrally formed on the inner air-duct layer (5); the inner air-duct layer (5) is arranged inside the heat-insulating layer (4), and the heat-insulating layer (4) is a rubber/plastic material. The modular flexible insulated air-duct system made by assembling a main air duct (7), a branched air duct (8), and a connecting air duct (9) may be rapidly connected on-site using a zip fastener to form an air-duct system having any configuration.

Abstract: An apparatus is described. The apparatus comprises a downstream wavelength selective switch having an input port, an optical path operable to carry an optical signal, an optical source providing amplified spontaneous emission (ASE) light, an optical switch having a first input coupled to the optical path, a second input coupled to the optical source and receiving the ASE light, and an output coupled to the input port of the downstream wavelength selective switch. The optical switch couples either the first input or the second input to the output. Further included is a photodiode operable to monitor the optical signal, detect an optical loss of signal of the optical signal, and output a switch signal to the optical switch such that the optical switch couples the second input receiving the ASE light to the output whereby the ASE light is directed to the input port of the downstream wavelength selective switch.

Abstract: The present invention discloses a multilayer composite rubber-plastic foam insulation material and a preparation method thereof. The composite rubber-plastic foam insulation material includes a two-layer structure; the two-layer structure includes an insulation layer and a first functional layer; the insulation layer and the first functional layer are both made of a rubber-plastic foam material; the first functional layer and the insulation layer are integrally molded by blending extrusion and vulcanization foaming, and the first functional layer and the insulation layer form an integral structure. The multilayer composite rubber-plastic foam insulation material provided by the present invention adopts a vulcanization foaming integral molding process, and not only ensures the thermal insulation property of the insulation layer, but also gives the functional layer corresponding functions by selecting different functional polymers, thereby satisfying a variety of personalized needs in engineering applications.

Abstract: Methods and systems for secure autonomic optical transport networks are disclosed, including a method of adding a network element in an optical network, comprising: verifying, with a new network element, a first identifier certificate from a proxy network element; verifying, with the proxy network element, a second identifier certificate from the new network element; using a registrar for verifying the second identifier certificate from the proxy network element and sending domain specific parameters to the proxy network element for forwarding to the new network element; generating, on the new network element, a local certificate derived from a secure module and sending it to the proxy network element for forwarding to the registrar; enrolling, with the registrar, the new network element in the autonomic domain; and signing, with the registrar, the local certificate and sending the signed local certificate to the new network element.